{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:41:07Z","timestamp":1791981667708,"version":"4.4.0"},"reference-count":8,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T00:00:00Z","timestamp":1191196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicology in Vitro"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1016\/j.tiv.2007.03.016","type":"journal-article","created":{"date-parts":[[2007,4,15]],"date-time":"2007-04-15T07:12:35Z","timestamp":1176621155000},"page":"1220-1226","source":"Crossref","is-referenced-by-count":166,"title":["Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro"],"prefix":"10.1016","volume":"21","author":[{"given":"A.","family":"Natsch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Gfeller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Rothaupt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Ellis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tiv.2007.03.016_bib1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1021\/tx050312l","article-title":"Cytosolic and nuclear protein targets of thiol-reactive electrophiles","volume":"19","author":"Dennehy","year":"2006","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tiv.2007.03.016_bib2","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/j.0105-1873.2005.00683.x","article-title":"Hapten-protein binding: from theory to practical application in the in vitro prediction of skin sensitization","volume":"53","author":"Divkovic","year":"2005","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.tiv.2007.03.016_bib3","doi-asserted-by":"crossref","first-page":"10070","DOI":"10.1073\/pnas.0502402102","article-title":"Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2","volume":"102","author":"Eggler","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.tiv.2007.03.016_bib4","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1093\/toxsci\/kfh213","article-title":"Development of a peptide reactivity assay for screening contact allergens","volume":"81","author":"Gerberick","year":"2004","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tiv.2007.03.016_bib5","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1111\/j.0105-1873.2004.00290.x","article-title":"A chemical dataset for evaluation of alternative approaches to skin-sensitization testing","volume":"50","author":"Gerberick","year":"2004","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.tiv.2007.03.016_bib6","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1021\/tx060102o","article-title":"Mechanistic applicability domain for non-animal based prediction of toxicological endpoints. QSAR analysis of the Schiff base applicability domain for skin sensitization","volume":"19","author":"Roberts","year":"2006","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tiv.2007.03.016_bib7","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/0003-2697(69)90064-5","article-title":"Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione","volume":"27","author":"Tietze","year":"1969","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.tiv.2007.03.016_bib8","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1073\/pnas.0307301101","article-title":"Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers","volume":"101","author":"Wakabayashi","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"}],"container-title":["Toxicology in Vitro"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0887233307001294?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0887233307001294?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,8]],"date-time":"2019-01-08T03:28:01Z","timestamp":1546918081000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0887233307001294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["S0887233307001294"],"URL":"https:\/\/doi.org\/10.1016\/j.tiv.2007.03.016","relation":{},"ISSN":["0887-2333"],"issn-type":[{"value":"0887-2333","type":"print"}],"subject":[],"published":{"date-parts":[[2007,10]]}}}