{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:34:13Z","timestamp":1790627653314,"version":"4.1.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007270","name":"University of Michigan","doi-asserted-by":"publisher","award":["BMU 20140481"],"award-info":[{"award-number":["BMU 20140481"]}],"id":[{"id":"10.13039\/100007270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007937","name":"Peking University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007937","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL127203"],"award-info":[{"award-number":["HL127203"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007270","name":"University of Michigan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007937","name":"Peking University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007937","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL127203"],"award-info":[{"award-number":["HL127203"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology in Vitro"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.tiv.2018.05.004","type":"journal-article","created":{"date-parts":[[2018,5,9]],"date-time":"2018-05-09T12:52:07Z","timestamp":1525870327000},"page":"95-105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"special_numbering":"C","title":["Variation in doses and duration of particulate matter exposure in bronchial epithelial cells results in upregulation of different genes associated with airway disorders"],"prefix":"10.1016","volume":"51","author":[{"given":"Priya","family":"Tripathi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Furong","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne M.","family":"Scruggs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yahong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2090-6331","authenticated-orcid":false,"given":"Steven K.","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tiv.2018.05.004_bb0005","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/ng1256","article-title":"Positional cloning of a novel gene influencing asthma from chromosome 2q14","volume":"35","author":"Allen","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.tiv.2018.05.004_bb0010","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.mrfmmm.2011.06.011","article-title":"Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: the role of polycyclic aromatic hydrocarbons","volume":"714","author":"Andrysik","year":"2011","journal-title":"Mutat. Res."},{"key":"10.1016\/j.tiv.2018.05.004_bb0015","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1165\/rcmb.2015-0391TR","article-title":"Transforming growth factor-beta: master regulator of the respiratory system in health and disease","volume":"54","author":"Aschner","year":"2016","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0020","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1023\/A:1007653900063","article-title":"Airborne particles evoke an inflammatory response in human airway epithelium. Activation of transcription factors","volume":"15","author":"Baeza-Squiban","year":"1999","journal-title":"Cell Biol. Toxicol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0025","first-page":"256","article-title":"A polymorphism in ORMDL3 is associated not only with asthma without rhinitis but also with chronic obstructive pulmonary disease","volume":"23","author":"Balantic","year":"2013","journal-title":"J Investig Allergol Clin Immunol"},{"key":"10.1016\/j.tiv.2018.05.004_bb0030","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.rmed.2011.11.007","article-title":"The role of SPINK5 in asthma related physiological events in the airway epithelium","volume":"106","author":"Birben","year":"2012","journal-title":"Respir. Med."},{"key":"10.1016\/j.tiv.2018.05.004_bb0035","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1152\/physiolgenomics.00096.2015","article-title":"Gene expression profiling of the effects of organic dust in lung epithelial and THP-1 cells reveals inductive effects on inflammatory and immune response genes","volume":"48","author":"Boggaram","year":"2016","journal-title":"Physiol. Genomics"},{"key":"10.1016\/j.tiv.2018.05.004_bb0040","first-page":"L25","article-title":"Mechanisms of GM-CSF increase by diesel exhaust particles in human airway epithelial cells","volume":"278","author":"Boland","year":"2000","journal-title":"Am. J. Phys. Lung Cell. Mol. Phys."},{"key":"10.1016\/j.tiv.2018.05.004_bb0045","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.envres.2014.10.010","article-title":"Genotoxic and epigenotoxic effects of fine particulate matter from rural and urban sites in Lebanon on human bronchial epithelial cells","volume":"136","author":"Borgie","year":"2015","journal-title":"Environ. Res."},{"key":"10.1016\/j.tiv.2018.05.004_bb0050","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.tiv.2012.11.008","article-title":"Development of a repeated exposure protocol of human bronchial epithelium in vitro to study the long-term effects of atmospheric particles","volume":"27","author":"Boublil","year":"2013","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.tiv.2018.05.004_bb0055","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/j.1365-2222.2009.03383.x","article-title":"Interleukin-13: prospects for new treatments","volume":"40","author":"Brightling","year":"2010","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.tiv.2018.05.004_bb0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/08958370802105405","article-title":"Effects of metals within ambient air particulate matter (PM) on human health","volume":"21","author":"Chen","year":"2009","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0065","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1016\/S0140-6736(13)62064-4","article-title":"China tackles the health effects of air pollution","volume":"382","author":"Chen","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.tiv.2018.05.004_bb0070","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.envres.2014.12.015","article-title":"Temporal-spatial variations of the physicochemical characteristics of air pollution Particulate Matter (PM2.5-0.3) and toxicological effects in human bronchial epithelial cells (BEAS-2B)","volume":"137","author":"Dergham","year":"2015","journal-title":"Environ. Res."},{"key":"10.1016\/j.tiv.2018.05.004_bb0075","doi-asserted-by":"crossref","first-page":"2513","DOI":"10.1056\/NEJMoa1702747","article-title":"Air pollution and mortality in the medicare population","volume":"376","author":"Di","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.tiv.2018.05.004_bb0080","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.toxlet.2014.04.010","article-title":"Global gene expression profiling of human bronchial epithelial cells exposed to airborne fine particulate matter collected from Wuhan, China","volume":"228","author":"Ding","year":"2014","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.tiv.2018.05.004_bb0085","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1743-8977-7-18","article-title":"Polycyclic aromatic hydrocarbon components contribute to the mitochondria-antiapoptotic effect of fine particulate matter on human bronchial epithelial cells via the aryl hydrocarbon receptor","volume":"7","author":"Ferecatu","year":"2010","journal-title":"Part Fibre Toxicol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0090","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1743-8977-10-25","article-title":"Growth of human bronchial epithelial cells at an air-liquid interface alters the response to particle exposure","volume":"10","author":"Ghio","year":"2013","journal-title":"Part Fibre Toxicol."},{"issue":"Suppl. 1","key":"10.1016\/j.tiv.2018.05.004_bb0095","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1080\/08958370701490551","article-title":"Assessing the role of particulate matter size and composition on gene expression in pulmonary cells","volume":"19","author":"Graff","year":"2007","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0100","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.pupt.2005.02.008","article-title":"ADAM33: a newly identified protease involved in airway remodelling","volume":"19","author":"Holgate","year":"2006","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.tiv.2018.05.004_bb0105","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1086\/338242","article-title":"Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma","volume":"70","author":"Howard","year":"2002","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.tiv.2018.05.004_bb0110","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1080\/10937404.2013.832649","article-title":"The role of in vitro gene expression profiling in particulate matter health research","volume":"16","author":"Huang","year":"2013","journal-title":"J. Toxicol. Environ. Health B Crit. Rev."},{"key":"10.1016\/j.tiv.2018.05.004_bb0115","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.scitotenv.2018.01.304","article-title":"Characterization and source identification of fine particulate matter in urban Beijing during the 2015 spring festival","volume":"628-629","author":"Ji","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.tiv.2018.05.004_bb0120","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/1476-069X-11-75","article-title":"Particulate matter air pollution and respiratory symptoms in individuals having either asthma or chronic obstructive pulmonary disease: a European multicentre panel study","volume":"11","author":"Karakatsani","year":"2012","journal-title":"Environ. Health"},{"key":"10.1016\/j.tiv.2018.05.004_bb0125","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.anai.2014.12.003","article-title":"Dipeptidyl-peptidase 10 as a genetic biomarker for the aspirin-exacerbated respiratory disease phenotype","volume":"114","author":"Kim","year":"2015","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.tiv.2018.05.004_bb0130","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.taap.2018.01.024","article-title":"Investigating mitochondrial dysfunction in human lung cells exposed to redox-active PM components","volume":"342","author":"Lavrich","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0135","article-title":"Urban particulate matter down-regulates filaggrin via COX2 expression\/PGE2 production leading to skin barrier dysfunction","volume":"6","author":"Lee","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tiv.2018.05.004_bb0140","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/nature15371","article-title":"The contribution of outdoor air pollution sources to premature mortality on a global scale","volume":"525","author":"Lelieveld","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.tiv.2018.05.004_bb0145","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.tiv.2017.04.014","article-title":"Transcriptomic analyses of human bronchial epithelial cells BEAS-2B exposed to atmospheric fine particulate matter PM2.5","volume":"42","author":"Li","year":"2017","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.tiv.2018.05.004_bb0150","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/1743-8977-10-63","article-title":"Cell cycle alterations induced by urban PM2.5 in bronchial epithelial cells: characterization of the process and possible mechanisms involved","volume":"10","author":"Longhin","year":"2013","journal-title":"Part Fibre Toxicol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0155","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.envpol.2015.11.013","article-title":"Integrative transcriptomic and protein analysis of human bronchial BEAS-2B exposed to seasonal urban particulate matter","volume":"209","author":"Longhin","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.tiv.2018.05.004_bb0160","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.envpol.2016.05.015","article-title":"Physico-chemical properties and biological effects of diesel and biomass particles","volume":"215","author":"Longhin","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.tiv.2018.05.004_bb0165","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.envpol.2017.08.099","article-title":"Atmospheric levels and cytotoxicity of polycyclic aromatic hydrocarbons and oxygenated-PAHs in PM2.5 in the Beijing-Tianjin-Hebei region","volume":"231","author":"Niu","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.tiv.2018.05.004_bb0170","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/pr.2013.186","article-title":"17q21 locus and ORMDL3: an increased risk for childhood asthma","volume":"75","author":"Ono","year":"2014","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.tiv.2018.05.004_bb0175","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.tox.2009.01.028","article-title":"Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution","volume":"259","author":"Ovrevik","year":"2009","journal-title":"Toxicology"},{"key":"10.1016\/j.tiv.2018.05.004_bb0180","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1165\/ajrcmb.19.1.3132","article-title":"Air pollution particles induce IL-6 gene expression in human airway epithelial cells via NF-kappaB activation","volume":"19","author":"Quay","year":"1998","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0185","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1093\/toxsci\/kfm018","article-title":"Assessing toxicity of fine and nanoparticles: comparing in vitro measurements to in vivo pulmonary toxicity profiles","volume":"97","author":"Sayes","year":"2007","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tiv.2018.05.004_bb0190","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1177\/096032706072520","article-title":"Particulate matter properties and health effects: consistency of epidemiological and toxicological studies","volume":"25","author":"Schwarze","year":"2006","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0195","doi-asserted-by":"crossref","first-page":"9862","DOI":"10.1007\/s11356-016-6228-x","article-title":"Human bronchial epithelial cells exposed in vitro to diesel exhaust particles exhibit alterations in cell rheology and cytotoxicity associated with decrease in antioxidant defenses and imbalance in pro- and anti-apoptotic gene expression","volume":"23","author":"Seriani","year":"2016","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.tiv.2018.05.004_bb0200","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1289\/ehp.1103594","article-title":"Ambient particulate matter induces interleukin-8 expression through an alternative NF-kappaB (nuclear factor-kappa B) mechanism in human airway epithelial cells","volume":"119","author":"Silbajoris","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.tiv.2018.05.004_bb0205","doi-asserted-by":"crossref","first-page":"6342","DOI":"10.1038\/s41598-017-06791-y","article-title":"Environment changes genetic effects on respiratory conditions and allergic phenotypes","volume":"7","author":"Song","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tiv.2018.05.004_bb0210","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1289\/ehp.1104389","article-title":"Respiratory health effects of airborne particulate matter: the role of particle size, composition, and oxidative potential-the RAPTES project","volume":"120","author":"Strak","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.tiv.2018.05.004_bb0215","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0891-5849(03)00280-6","article-title":"Reactive oxygen species in pulmonary inflammation by ambient particulates","volume":"35","author":"Tao","year":"2003","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.tiv.2018.05.004_bb0220","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1093\/toxsci\/kfl165","article-title":"Particokinetics in vitro: dosimetry considerations for in vitro nanoparticle toxicity assessments","volume":"95","author":"Teeguarden","year":"2007","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tiv.2018.05.004_bb0225","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1093\/aje\/kwm218","article-title":"Invited commentary: heterogeneity of particulate matter health risks","volume":"166","author":"Tolbert","year":"2007","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0230","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/572025","article-title":"ADAM metallopeptidase domain 33 (ADAM33): a promising target for asthma","volume":"2014","author":"Tripathi","year":"2014","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.tiv.2018.05.004_bb0235","doi-asserted-by":"crossref","DOI":"10.1093\/toxsci\/kfy053","article-title":"Air-liquid interface: relevant in vitro models for investigating air pollutant-induced pulmonary toxicity","author":"Upadhyay","year":"2018","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tiv.2018.05.004_bb0240","doi-asserted-by":"crossref","first-page":"4398","DOI":"10.21037\/jtd.2017.09.135","article-title":"Urban particulate matter triggers lung inflammation via the ROS-MAPK-NF-kappaB signaling pathway","volume":"9","author":"Wang","year":"2017","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.tiv.2018.05.004_bb0245","doi-asserted-by":"crossref","first-page":"25071","DOI":"10.1007\/s11356-017-0090-3","article-title":"Fine particle matters induce DNA damage and G2\/M cell cycle arrest in human bronchial epithelial BEAS-2B cells","volume":"24","author":"Wu","year":"2017","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.tiv.2018.05.004_bb0250","first-page":"E69","article-title":"The impact of PM2.5 on the human respiratory system","volume":"8","author":"Xing","year":"2016","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.tiv.2018.05.004_bb0255","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1002\/tox.22102","article-title":"Pro-inflammatory response and oxidative stress induced by specific components in ambient particulate matter in human bronchial epithelial cells","volume":"31","author":"Yang","year":"2016","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0260","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.etap.2017.06.012","article-title":"Effects of 1,4-naphthoquinone aged carbon black particles on the cell membrane of human bronchial epithelium","volume":"54","author":"Zhang","year":"2017","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0265","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1165\/rcmb.2008-0105OC","article-title":"Regulation of COX-2 expression and IL-6 release by particulate matter in airway epithelial cells","volume":"40","author":"Zhao","year":"2009","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.tiv.2018.05.004_bb0270","article-title":"Transcriptomic analyses of the biological effects of airborne PM2.5 exposure on human bronchial epithelial cells","volume":"10","author":"Zhou","year":"2015","journal-title":"PLoS One"}],"container-title":["Toxicology in Vitro"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0887233318301553?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0887233318301553?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:30:16Z","timestamp":1760135416000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0887233318301553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":54,"alternative-id":["S0887233318301553"],"URL":"https:\/\/doi.org\/10.1016\/j.tiv.2018.05.004","relation":{},"ISSN":["0887-2333"],"issn-type":[{"value":"0887-2333","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Variation in doses and duration of particulate matter exposure in bronchial epithelial cells results in upregulation of different genes associated with airway disorders","name":"articletitle","label":"Article Title"},{"value":"Toxicology in Vitro","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tiv.2018.05.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}