{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:02:44Z","timestamp":1777496564142,"version":"3.51.4"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"publisher","award":["2015\/20221-7"],"award-info":[{"award-number":["2015\/20221-7"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"publisher","award":["2016\/03455-7"],"award-info":[{"award-number":["2016\/03455-7"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["2015\/20221-7"],"award-info":[{"award-number":["2015\/20221-7"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["2016\/03455-7"],"award-info":[{"award-number":["2016\/03455-7"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology in Vitro"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.tiv.2021.105211","type":"journal-article","created":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T14:17:46Z","timestamp":1625667466000},"page":"105211","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Effect of processing methods on the cytotoxicity of methyl methacrylate-based ocular prostheses: An in vitro study"],"prefix":"10.1016","volume":"76","author":[{"given":"Emily Vivianne Freitas","family":"da Silva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo Coelho","family":"Goiato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandro Basso","family":"Bitencourt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoav","family":"Finer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor Gustavo Balera","family":"Brito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline Satie","family":"Takamiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra Helena Penha","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela Micheline","family":"dos Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tiv.2021.105211_bb0005","series-title":"Imunologia celular e molecular. 2a ed.","first-page":"253","article-title":"Citocinas","author":"Abbas","year":"1998"},{"key":"10.1016\/j.tiv.2021.105211_bb0010","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0022-3913(09)60200-6","article-title":"Effect of polymerization methods and thermal cycling on color stability of acrylic resin denture teeth","volume":"102","author":"Assun\u00e7\u00e3o","year":"2009","journal-title":"J. Prosthet. Dent."},{"key":"10.1016\/j.tiv.2021.105211_bb0015","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1002\/jbm.b.31473","article-title":"In vitro comparison of the cytotoxicity of acetal resin, heat-polymerized resin, and auto-polymerized resin as denture base materials","volume":"91","author":"Ata","year":"2009","journal-title":"J. Biomed. Mater. Res. - Part B Appl. Biomater."},{"key":"10.1016\/j.tiv.2021.105211_bb0020","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.actbio.2008.07.021","article-title":"N-Acetyl cysteine prevents suppression of oral fibroblast function on poly(methylmethacrylate) resin","volume":"5","author":"Att","year":"2009","journal-title":"Acta Biomater."},{"key":"10.1016\/j.tiv.2021.105211_bb0025","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1080\/08958370500225240","article-title":"Toxicity assessment of industrial chemicals and airborne contaminants: transition from In Vivo to In Vitro test methods: a review","volume":"17","author":"Bakand","year":"2005","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.tiv.2021.105211_bb0030","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1002\/jbm.b.31194","article-title":"In vitro cytotoxicity of maxillofacial silicone elastomers: effect of accelerated aging","volume":"89B","author":"Bal","year":"2009","journal-title":"J. Biomed. Mater. Res. Part B Appl. Biomater."},{"key":"10.1016\/j.tiv.2021.105211_bb0035","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1741-2358.2008.00218.x","article-title":"Bond strength of denture teeth to acrylic resin: effect of thermocycling and polymerisation methods","volume":"25","author":"Barbosa","year":"2008","journal-title":"Gerodontology"},{"key":"10.1016\/j.tiv.2021.105211_bb0040","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1741-2358.2008.00262.x","article-title":"Effect of monomer treatment and polymerisation methods on the bond strength of resin teeth to denture base material","volume":"26","author":"Barbosa","year":"2009","journal-title":"Gerodontology"},{"key":"10.1016\/j.tiv.2021.105211_bb0045","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.memsci.2015.05.059","article-title":"Facile evaluation of coating thickness on membranes using ATR-FTIR","volume":"492","author":"Bass","year":"2015","journal-title":"J. Membr. Sci."},{"key":"10.1016\/j.tiv.2021.105211_bb0050","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1002\/jbm.b.30377","article-title":"Influence of polymerization method, curing process, and length of time of storage in water on the residual methyl methacrylate content in dental acrylic resins","volume":"76","author":"Bayraktar","year":"2006","journal-title":"J. Biomed. Mater. Res. - Part B Appl. Biomater."},{"key":"10.1016\/j.tiv.2021.105211_bb0055","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1136\/bmj.321.7258.424","article-title":"Science commentary: Th1 and Th2 responses: what are they?","volume":"321","author":"Berger","year":"2000","journal-title":"Bmj"},{"key":"10.1016\/j.tiv.2021.105211_bb0060","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.bbi.2010.12.012","article-title":"Stress hormones increase cell proliferation and regulates interleukin-6 secretion in human oral squamous cell carcinoma cells","volume":"25","author":"Bernab\u00e9","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.tiv.2021.105211_bb0065","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1590\/S1678-77572011005000002","article-title":"Effect of leaching residual methyl methacrylate concentrations on in vitro cytotoxicity of heat polymerized denture base acrylic resin processed with different polymerization cycles","volume":"19","author":"Bural","year":"2011","journal-title":"J. Appl. Oral Sci."},{"key":"10.1016\/j.tiv.2021.105211_bb0070","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/j.dental.2011.08.007","article-title":"Effect of post-polymerization heat-treatments on degree of conversion, leaching residual MMA and in vitro cytotoxicity of autopolymerizing acrylic repair resin","volume":"27","author":"Bural","year":"2011","journal-title":"Dent. Mater."},{"key":"10.1016\/j.tiv.2021.105211_bb0075","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1532-849X.2009.00522.x","article-title":"Color stability, surface roughness, and surface porosity of acrylic resins for eye sclera polymerized by different heat sources","volume":"19","author":"Canadas","year":"2010","journal-title":"J. Prosthodont."},{"key":"10.1016\/j.tiv.2021.105211_bb0080","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0022-3913(12)60037-7","article-title":"Cytotoxicity of denture base and hard chairside reline materials: a systematic review","volume":"107","author":"Chaves","year":"2012","journal-title":"J. Prosthet. Dent."},{"key":"10.1016\/j.tiv.2021.105211_bb0085","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1034\/j.1600-0722.2000.00730.x","article-title":"Patterns of cell death induced by eluates from denture base acrylic resins in U-937 human monoblastoid cells","volume":"108","author":"Cimpan","year":"2000","journal-title":"Eur. J. Oral Sci."},{"key":"10.1016\/j.tiv.2021.105211_bb0090","first-page":"851","article-title":"Brignole-Baudouin. Hyperosmolarity potentiates toxic effects of benzalkonium chloride on conjunctival epithelial cells in vitro","volume":"18","author":"Clouzeau","year":"2012","journal-title":"Mol. Vis."},{"key":"10.1016\/j.tiv.2021.105211_bb0095","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.prosdent.2004.01.006","article-title":"The effect of polymerization cycles on porosity of microwave-processed denture base resin","volume":"91","author":"Compagnoni","year":"2004","journal-title":"J. Prosthet. Dent."},{"key":"10.1016\/j.tiv.2021.105211_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.prosdent.2016.06.001","article-title":"Effect of different methods of polymerizing ocular prosthesis acrylic resin on a human conjunctival cell line","volume":"116","author":"da Silva","year":"2016","journal-title":"J. Prosthet. Dent."},{"key":"10.1016\/j.tiv.2021.105211_bb0105","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.tiv.2016.08.005","article-title":"Toxicity analysis of ocular prosthesis acrylic resin with or without pigment incorporation in human conjunctival cell line","volume":"36","author":"da Silva","year":"2016","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.tiv.2021.105211_bb0110","article-title":"Influence of preparation and exposure periods of eluates from ocular prosthesis acrylic resin in human conjunctival cell line","volume":"23","author":"da Silva","year":"2019","journal-title":"Iran. Biomed. J."},{"issue":"180\u20138","key":"10.1016\/j.tiv.2021.105211_bb0115","article-title":"Evaluation of cellular toxicity of three denture base acrylic resins","volume":"9","author":"Ebrahimi Saravi","year":"2012","journal-title":"J. Dent. (Tehran)."},{"key":"10.1016\/j.tiv.2021.105211_bb0120","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1590\/S1806-83242009000300007","article-title":"Assessment of the flexural strength of two heat-curing acrylic resins for artificial eyes","volume":"23","author":"Fernandes","year":"2008","journal-title":"Braz. Oral Res."},{"key":"10.1016\/j.tiv.2021.105211_bb0125","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.clae.2009.12.008","article-title":"Effect of weathering and thickness on roughness of acrylic resin and ocular button","volume":"33","author":"Fernandes","year":"2010","journal-title":"Contact Lens Anterior Eye"},{"issue":"B","key":"10.1016\/j.tiv.2021.105211_bb0130","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1002\/jbm.b.32673","article-title":"Biocompatibility of polymethylmethacrylate resins used in dentistry","volume":"100","author":"Gautam","year":"2012","journal-title":"J. Biomed. Mater. Res. - Part B Appl. Biomater."},{"key":"10.1016\/j.tiv.2021.105211_bb0135","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1590\/S1678-77572010000600018","article-title":"Chromatic stability of acrylic resins of artificial eyes submitted to accelerated aging and polishing","volume":"18","author":"Goiato","year":"2010","journal-title":"J. Appl. Oral Sci."},{"key":"10.1016\/j.tiv.2021.105211_bb0140","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1111\/j.1741-2358.2011.00570.x","article-title":"Effect of disinfection and storage on the flexural strength of ocular prosthetic acrylic resins","volume":"29","author":"Goiato","year":"2012","journal-title":"Gerodontology"},{"key":"10.1016\/j.tiv.2021.105211_bb0145","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.1741-2358.2012.00676.x","article-title":"Effect of thermal cycling and disinfection on colour stability of denture base acrylic resin","volume":"30","author":"Goiato","year":"2013","journal-title":"Gerodontology"},{"key":"10.1016\/j.tiv.2021.105211_bb0150","doi-asserted-by":"crossref","first-page":"203","DOI":"10.3109\/03091902.2013.774444","article-title":"Effect of thermal cycling and disinfection on microhardness of acrylic resin denture base","volume":"37","author":"Goiato","year":"2013","journal-title":"J. Med. Eng. Technol."},{"key":"10.1016\/j.tiv.2021.105211_bb0155","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3109\/01676830.2014.881395","article-title":"Fabrication techniques for ocular prostheses-an overview","volume":"33","author":"Goiato","year":"2014","journal-title":"Orbit"},{"key":"10.1016\/j.tiv.2021.105211_bb0160","doi-asserted-by":"crossref","first-page":"679","DOI":"10.17219\/acem\/33009","article-title":"Acrylic resin cytotoxicity for denture base - literature review","volume":"24","author":"Goiato","year":"2015","journal-title":"Adv. Clin. Exp. Med."},{"key":"10.1016\/j.tiv.2021.105211_bb0165","doi-asserted-by":"crossref","first-page":"926","DOI":"10.2319\/072407-343.1","article-title":"Cytotoxicity of two autopolymerized acrylic resins used in orthodontics","volume":"78","author":"Gon\u00e7alves","year":"2008","journal-title":"Angle Orthod."},{"key":"10.1016\/j.tiv.2021.105211_bb0170","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.saa.2015.06.084","article-title":"FT-IR and FT-Raman studies of cross-linking processes with Ca2+ ions, glutaraldehyde and microwave radiation for polymer composition of poly(acrylic acid)\/sodium salt of carboxymethyl starch - In moulding sands","volume":"151","author":"Grabowska","year":"2015","journal-title":"Part II. Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.tiv.2021.105211_bb0175","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/toxsci\/kfp149","article-title":"Are in vitro tests suitable for regulatory use?","volume":"111","author":"Hartung","year":"2009","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tiv.2021.105211_bb0180","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1042\/bj2650621","article-title":"Interleukin-6 and the acute phase response","volume":"265","author":"Heinrich","year":"1990","journal-title":"Biochem. J."},{"key":"10.1016\/j.tiv.2021.105211_bb0185","first-page":"439","article-title":"Cytotoxic effects of denture base materials on a permanent human oral epithelial cell line and on primary human oral fibroblasts in vitro","volume":"14","author":"Huang","year":"2001","journal-title":"Int. J. Prosthodont."},{"key":"10.1016\/j.tiv.2021.105211_bb0190","article-title":"ISO 10993-5: biological evaluation of medical devices \u2013 Part 5: Tests for in vitro cytotoxicity. Genebra","author":"International Organization for Standardization","year":"2009","journal-title":"ISO"},{"key":"10.1016\/j.tiv.2021.105211_bb0195","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1002\/(SICI)1097-4628(19970207)63:6<787::AID-APP11>3.0.CO;2-S","article-title":"Microwave polymerization of poly(methyl acrylate): conversion studies at variable power","volume":"63","author":"Jacob","year":"1997","journal-title":"J. Appl. Polym. Sci."},{"key":"10.1016\/j.tiv.2021.105211_bb0200","first-page":"340","article-title":"Cytotoxicity of denture base resins: effect of water bath and microwave postpolymerization heat treatments","volume":"17","author":"Jorge","year":"2004","journal-title":"Int. J. Prosthodont."},{"key":"10.1016\/j.tiv.2021.105211_bb0205","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1741-2358.2007.00146.x","article-title":"Biocompatibility of denture base acrylic resins evaluated in culture of L929 cells. Effect of polymerisation cycle and post-polymerisation treatments","volume":"24","author":"Jorge","year":"2007","journal-title":"Gerodontology"},{"key":"10.1016\/j.tiv.2021.105211_bb0210","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.dental.2005.09.002","article-title":"Involvement of oxidative stress in mutagenicity and apoptosis caused by dental resin monomers in cell cultures","volume":"22","author":"Lee","year":"2006","journal-title":"Dent. Mater."},{"key":"10.1016\/j.tiv.2021.105211_bb0215","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.2147\/IJN.S29945","article-title":"Antitumor activity of celastrol nanoparticles in a xenograft retinoblastoma tumor model","volume":"7","author":"Li","year":"2012","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.tiv.2021.105211_bb0220","doi-asserted-by":"crossref","first-page":"142","DOI":"10.5966\/sctm.2011-0018","article-title":"Concise review: role of mesenchymal stem cells in wound repair","volume":"1","author":"Maxson","year":"2012","journal-title":"Stem Cells Transl. Med."},{"key":"10.1016\/j.tiv.2021.105211_bb0225","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.dental.2008.01.010","article-title":"Cytotoxicity of silica-glass fiber reinforced composites","volume":"24","author":"Meri\u00e7","year":"2008","journal-title":"Dent. Mater."},{"key":"10.1016\/j.tiv.2021.105211_bb0230","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.biocel.2004.04.007","article-title":"Mcl-1","volume":"37","author":"Michels","year":"2005","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.tiv.2021.105211_bb0235","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1532-849X.2011.00772.x","article-title":"Silver distribution and release from an antimicrobial Denture Base resin containing silver colloidal nanoparticles","volume":"21","author":"Monteiro","year":"2012","journal-title":"J. Prosthodont."},{"key":"10.1016\/j.tiv.2021.105211_bb0240","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1016\/j.joen.2011.08.004","article-title":"Studies on the expression of fibroblast growth factor-2 from odontoblast-like cells","volume":"37","author":"Oliveira","year":"2011","journal-title":"J. Endod."},{"key":"10.1016\/j.tiv.2021.105211_bb0245","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1002\/jbm.b.31430","article-title":"Enzyme-catalyzed hydrolysis of dentin adhesives containing a new urethane-based trimethacrylate monomer","volume":"91","author":"Park","year":"2009","journal-title":"J. Biomed. Mater. Res. - Part B Appl. Biomater."},{"key":"10.1016\/j.tiv.2021.105211_bb0250","first-page":"707","article-title":"A survey of prosthetic eye wearers to investigate mucoid discharge","volume":"6","author":"Pine","year":"2012","journal-title":"Clin. Ophthalmol."},{"key":"10.1016\/j.tiv.2021.105211_bb0255","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.mehy.2013.04.024","article-title":"A proposed model of the response of the anophthalmic socket to prosthetic eye wear and its application to the management of mucoid discharge","volume":"81","author":"Pine","year":"2013","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.tiv.2021.105211_bb0260","doi-asserted-by":"crossref","first-page":"2334","DOI":"10.1002\/jbm.a.35770","article-title":"Development of a nanofibrous wound dressing with an antifibrogenic properties in vitro and in vivo model","volume":"104","author":"Poormasjedi-Meibod","year":"2016","journal-title":"J. Biomed. Mater. Res. - Part A"},{"key":"10.1016\/j.tiv.2021.105211_bb0265","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jpor.2012.08.006","article-title":"Custom ocular prosthesis: comparison of two different techniques","volume":"57","author":"Prithviraj","year":"2013","journal-title":"J. Prosthodont. Res."},{"key":"10.1016\/j.tiv.2021.105211_bb0270","doi-asserted-by":"crossref","first-page":"12347","DOI":"10.3390\/s120912347","article-title":"Multiple applications of alamar blue as an indicator of metabolic function and cellular health in cell viability bioassays","volume":"12","author":"Rampersad","year":"2012","journal-title":"Sensors (Switzerland)"},{"key":"10.1016\/j.tiv.2021.105211_bb0275","doi-asserted-by":"crossref","first-page":"913","DOI":"10.3109\/02713680903198045","article-title":"Tissue engineering for conjunctival reconstruction: established methods and future outlooks","volume":"34","author":"Schrader","year":"2009","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.tiv.2021.105211_bb0280","first-page":"73","article-title":"Cytotoxicity of denture base resins","volume":"10","author":"Sheridan","year":"1997","journal-title":"Int. J. Prosthodont."},{"key":"10.1016\/j.tiv.2021.105211_bb0285","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1165\/ajrcmb\/8.6.640","article-title":"Type IV collagen production by rat pulmonary alveolar epithelial cells","volume":"8","author":"Simon","year":"1993","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.tiv.2021.105211_bb0290","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/j.1741-2358.2011.00463.x","article-title":"Effect of water storage and heat treatment on the cytotoxicity of soft liners","volume":"29","author":"Tay","year":"2012","journal-title":"Gerodontology"},{"key":"10.1016\/j.tiv.2021.105211_bb0295","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/318481","article-title":"TGF-\u03b2: an important mediator of allergic disease and a molecule with dual activity in cancer development","volume":"2014","author":"Tirado-Rodriguez","year":"2014","journal-title":"J Immunol Res"},{"key":"10.1016\/j.tiv.2021.105211_bb0300","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1177\/039463201202500310","article-title":"Morphological analysis and interleukin release in human gingival fibroblasts seeded on different denture base acrylic resins","volume":"25","author":"Trubiani","year":"2012","journal-title":"Int. J. Immunopathol. Pharmacol."},{"key":"10.1016\/j.tiv.2021.105211_bb0305","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.yrtph.2008.02.002","article-title":"Replacement of in vivo acute oral toxicity studies by in vitro cytotoxicity methods: opportunities, limits and regulatory status","volume":"51","author":"Ukelis","year":"2008","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.tiv.2021.105211_bb0310","first-page":"363","article-title":"Residual monomer of reline acrylic resins","volume":"23","author":"Urban","year":"2007","journal-title":"Effect of water-bath and microwave post-polymerization treatments. Dent. Mater."},{"key":"10.1016\/j.tiv.2021.105211_bb0315","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.dental.2008.10.017","article-title":"Effect of water-bath post-polymerization on the mechanical properties, degree of conversion, and leaching of residual compounds of hard chairside reline resins","volume":"25","author":"Urban","year":"2009","journal-title":"Dent. Mater."},{"key":"10.1016\/j.tiv.2021.105211_bb0320","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0165-6147(93)90201-T","article-title":"IL-2\/IL-2 receptor system: a target for rational immune intervention","volume":"14","author":"Waldmann","year":"1993","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.tiv.2021.105211_bb0325","doi-asserted-by":"crossref","first-page":"446","DOI":"10.2165\/00003495-199346030-00009","article-title":"Interleukin-2. A review of its pharmacological properties and therapeutic use in patients with cancer","volume":"46","author":"Whittington","year":"1993","journal-title":"Drugs"},{"key":"10.1016\/j.tiv.2021.105211_bb0330","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1179\/135100009X392430","article-title":"N -acetyl cysteine restores viability and function of rat odontoblast-like cells impaired by polymethylmethacrylate dental resin extract","volume":"14","author":"Yamada","year":"2009","journal-title":"Redox Rep."},{"key":"10.1016\/j.tiv.2021.105211_bb0335","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1080\/09553000701558977","article-title":"Matrix-Metallo-proteinases and their tissue inhibitors in radiation-induced lung injury","volume":"83","author":"Yang","year":"2007","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.tiv.2021.105211_bb0340","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1067\/mpr.2002.124490","article-title":"Evaluation of porosity in microwave-processed acrylic resin using a photographic method","volume":"87","author":"Yannikakis","year":"2002","journal-title":"J. Prosthet. Dent."}],"container-title":["Toxicology in Vitro"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0887233321001363?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0887233321001363?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:37:50Z","timestamp":1760135870000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0887233321001363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":68,"alternative-id":["S0887233321001363"],"URL":"https:\/\/doi.org\/10.1016\/j.tiv.2021.105211","relation":{},"ISSN":["0887-2333"],"issn-type":[{"value":"0887-2333","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of processing methods on the cytotoxicity of methyl methacrylate-based ocular prostheses: An in vitro study","name":"articletitle","label":"Article Title"},{"value":"Toxicology in Vitro","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tiv.2021.105211","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105211"}}