{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T14:48:57Z","timestamp":1781880537681,"version":"3.54.5"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T00:00:00Z","timestamp":1768608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003793","name":"Heart and Lung Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004348","name":"Region Stockholm","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004348","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002960","name":"Region V\u00e4sterbotten","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002960","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology in Vitro"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.tiv.2026.106199","type":"journal-article","created":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T16:39:58Z","timestamp":1768667998000},"page":"106199","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Chemical characterisation and cytotoxic analysis of an electronic cigarette and heated tobacco product compared to a conventional cigarette in human lung cell lines"],"prefix":"10.1016","volume":"112","author":[{"given":"Gregory","family":"Rankin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e5kan","family":"Wingfors","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"\u00d6berg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Blomberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linnea","family":"Hedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny A.","family":"Bosson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Lundb\u00e4ck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tiv.2026.106199_bb0005","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s12012-019-09516-x","article-title":"Acute effects of electronic cigarette inhalation on the vasculature and the conducting airways","volume":"19","author":"Antoniewicz","year":"2019","journal-title":"Cardiovasc. Toxicol."},{"key":"10.1016\/j.tiv.2026.106199_bb0010","doi-asserted-by":"crossref","first-page":"H262","DOI":"10.1152\/ajpheart.00192.2020","article-title":"Acute and chronic sympathomimetic effects of e-cigarette and tobacco cigarette smoking: role of nicotine and non-nicotine constituents","volume":"319","author":"Arastoo","year":"2020","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"Suppl. 2","key":"10.1016\/j.tiv.2026.106199_bb0015","first-page":"S18","article-title":"Clinical pharmacology of electronic nicotine delivery systems (ENDS): implications for benefits and risks in the promotion of the combusted tobacco endgame","volume":"61","author":"Benowitz","year":"2021","journal-title":"J. Clin. Pharmacol."},{"issue":"11","key":"10.1016\/j.tiv.2026.106199_bib263","doi-asserted-by":"crossref","first-page":"2675","DOI":"10.1007\/s00216-020-02502-1","article-title":"Comprehensive chemical characterization of aerosol generated by heated tobacco product by untargeted screeening","volume":"412","author":"Bentley","year":"2020","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.tiv.2026.106199_bb0020","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.010455","article-title":"Acute effects of heat-not-burn, electronic vaping, and traditional tobacco combustion cigarettes: the Sapienza University of Rome-vascular assessment of Proatherosclerotic effects of smoking (SUR - VAPES) 2 randomized trial","volume":"8","author":"Biondi-Zoccai","year":"2019","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.tiv.2026.106199_bb0025","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1021\/acs.chemrestox.0c00088","article-title":"Free radical production and characterization of heat-not-burn cigarettes in comparison to conventional and electronic cigarettes","volume":"33","author":"Bitzer","year":"2020","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tiv.2026.106199_bb0030","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1021\/acs.chemrestox.8b00089","article-title":"Presence of the carcinogen N\u2019-Nitrosonornicotine in saliva of E-cigarette users","volume":"31","author":"Bustamante","year":"2018","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tiv.2026.106199_bb0035","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s13181-020-00772-w","article-title":"Review of health consequences of electronic cigarettes and the outbreak of electronic cigarette, or vaping, product use-associated lung injury","volume":"16","author":"Cao","year":"2020","journal-title":"J. Med. Toxicol."},{"issue":"9","key":"10.1016\/j.tiv.2026.106199_bb0040","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1164\/rccm.201811-2087OC","article-title":"Electronic cigarette vapor with nicotine causes airway Mucociliary dysfunction preferentially via TRPA1 receptors","volume":"200","author":"Chung","year":"2019","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.tiv.2026.106199_bb0045","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1136\/tobaccocontrol-2017-054104","article-title":"iQOS: evidence of pyrolysis and release of a toxicant from plastic","volume":"28","author":"Davis","year":"2019","journal-title":"Tob. Control"},{"key":"10.1016\/j.tiv.2026.106199_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.123417","article-title":"Comparison of the chemical composition of aerosols from heated tobacco products, electronic cigarettes and tobacco cigarettes and their toxic impacts on the human bronchial epithelial BEAS-2B cells","volume":"401","author":"Dusautoir","year":"2021","journal-title":"J. Hazard. Mater."},{"issue":"6","key":"10.1016\/j.tiv.2026.106199_bb0055","doi-asserted-by":"crossref","first-page":"L1064","DOI":"10.1152\/ajplung.00525.2020","article-title":"Differential responses to e-cigarette generated aerosols from humectants and different forms of nicotine in epithelial cells from nonsmokers and smokers","volume":"320","author":"Escobar","year":"2021","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"10.1016\/j.tiv.2026.106199_bb0060","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1111\/add.14365","article-title":"Carbonyl emissions from a novel heated tobacco product (IQOS): comparison with an e-cigarette and a tobacco cigarette","volume":"113","author":"Farsalinos","year":"2018","journal-title":"Addiction"},{"key":"10.1016\/j.tiv.2026.106199_bb0065","doi-asserted-by":"crossref","first-page":"H1234","DOI":"10.1152\/ajpheart.00708.2020","article-title":"Heat-not-burn tobacco products: an emerging threat to cardiovascular health","volume":"319","author":"Fried","year":"2020","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"12","key":"10.1016\/j.tiv.2026.106199_bb0070","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1136\/thoraxjnl-2015-208039","article-title":"Chronic electronic cigarette exposure in mice induces features of COPD in a nicotine-dependent manner","volume":"71","author":"Garcia-Arcos","year":"2016","journal-title":"Thorax"},{"key":"10.1016\/j.tiv.2026.106199_bb0075","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1164\/rccm.201710-2033OC","article-title":"Chronic E-cigarette exposure alters the human bronchial epithelial proteome","volume":"198","author":"Ghosh","year":"2018","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.tiv.2026.106199_bb0080","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.toxlet.2011.09.029","article-title":"Analysis of nicotine-induced DNA damage in cells of the human respiratory tract","volume":"208","author":"Ginzkey","year":"2012","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.tiv.2026.106199_bb0085","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2018.5937","article-title":"Comparison of nicotine and toxicant exposure in users of electronic cigarettes and combustible cigarettes","volume":"1","author":"Goniewicz","year":"2018","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.tiv.2026.106199_bb0090","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1465-9921-9-47","article-title":"Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study","volume":"9","author":"Hackett","year":"2008","journal-title":"Respir. Res."},{"key":"10.1016\/j.tiv.2026.106199_bb0095","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1177\/2047487320918365","article-title":"Acute effect of heat-not-burn versus standard cigarette smoking on arterial stiffness and wave reflections in young smokers","volume":"28","author":"Ioakeimidis","year":"2021","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.tiv.2026.106199_bb0100","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1093\/ntr\/ntz021","article-title":"Characterization of volatile organic compound metabolites in cigarette smokers, electronic nicotine device users, dual users, and nonusers of tobacco","volume":"22","author":"Keith","year":"2020","journal-title":"Nicotine Tob. Res."},{"issue":"7","key":"10.1016\/j.tiv.2026.106199_bb0105","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1021\/acs.chemrestox.2c00110","article-title":"Effects of common e-liquid Flavorants and added nicotine on toxicant formation during vaping analyzed by (1)H NMR spectroscopy","volume":"35","author":"Kerber","year":"2022","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tiv.2026.106199_bb0110","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1093\/ntr\/nts172","article-title":"Nornicotine nitrosation in saliva and its relation to endogenous synthesis of N\u2019-nitrosonornicotine in humans","volume":"15","author":"Knezevich","year":"2013","journal-title":"Nicotine Tob. Res."},{"key":"10.1016\/j.tiv.2026.106199_bb0115","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1093\/ntr\/ntu078","article-title":"Carbonyl compounds in electronic cigarette vapors: effects of nicotine solvent and battery output voltage","volume":"16","author":"Kosmider","year":"2014","journal-title":"Nicotine Tob. Res."},{"key":"10.1016\/j.tiv.2026.106199_bb0120","first-page":"E1560","article-title":"E-cigarette smoke damages DNA and reduces repair activity in mouse lung, heart, and bladder as well as in human lung and bladder cells","volume":"115","author":"Lee","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"3","key":"10.1016\/j.tiv.2026.106199_bb0125","doi-asserted-by":"crossref","DOI":"10.4491\/eer.2023.601","article-title":"Acetic acid production by the two-step thermal treatment of tobacco filter","volume":"29","author":"Lee","year":"2024","journal-title":"Environ. Eng. Res."},{"key":"10.1016\/j.tiv.2026.106199_bb0130","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1093\/ntr\/nty089","article-title":"Comparison of urinary biomarkers of exposure in humans using electronic cigarettes, combustible cigarettes, and smokeless tobacco","volume":"21","author":"Lorkiewicz","year":"2019","journal-title":"Nicotine Tob. Res."},{"key":"10.1016\/j.tiv.2026.106199_bb0135","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s12012-023-09802-9","article-title":"Electronic cigarette vaping with nicotine causes increased thrombogenicity and impaired microvascular function in healthy volunteers: a randomised clinical trial","volume":"23","author":"Lyytinen","year":"2023","journal-title":"Cardiovasc. Toxicol."},{"key":"10.1016\/j.tiv.2026.106199_bb0140","article-title":"Use of heated tobacco products (IQOS) causes an acute increase in arterial stiffness and platelet thrombus formation","author":"Lyytinen","year":"2023","journal-title":"Atherosclerosis"},{"issue":"1","key":"10.1016\/j.tiv.2026.106199_bb0145","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s12931-024-02697-2","article-title":"In vitro toxicological evaluation of aerosols generated by a 4th generation vaping device using nicotine salts in an air-liquid interface system","volume":"25","author":"Mercier","year":"2024","journal-title":"Respir. Res."},{"key":"10.1016\/j.tiv.2026.106199_bb0150","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21020652","article-title":"A summary of in vitro and in vivo studies evaluating the impact of E-cigarette exposure on living organisms and the environment","volume":"21","author":"Merecz-Sadowska","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tiv.2026.106199_bb0155","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.atherosclerosis.2020.02.010","article-title":"Electronic cigarettes containing nicotine increase endothelial and platelet derived extracellular vesicles in healthy volunteers","volume":"301","author":"Mobarrez","year":"2020","journal-title":"Atherosclerosis"},{"issue":"6","key":"10.1016\/j.tiv.2026.106199_bb0160","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1021\/acs.chemrestox.8b00381","article-title":"High-nicotine electronic cigarette products: toxicity of JUUL fluids and aerosols correlates strongly with nicotine and some flavor chemical concentrations","volume":"32","author":"Omaiye","year":"2019","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tiv.2026.106199_bb0165","article-title":"Acute effects of a heat-not-burn tobacco product on pulmonary function","volume":"56","author":"Pataka","year":"2020","journal-title":"Medicina (Kaunas)"},{"issue":"1","key":"10.1016\/j.tiv.2026.106199_bib264","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/s12931-023-02438-x","article-title":"Transcriptomic responses in the blood and sputum of cigarette of cigarette smokers compared to e-cigarette vapers","volume":"24","author":"Perez","year":"2023","journal-title":"Respir. Res."},{"key":"10.1016\/j.tiv.2026.106199_bb0170","author":"Phillip Morris International (PMI)"},{"issue":"1","key":"10.1016\/j.tiv.2026.106199_bb0175","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s12950-023-00367-6","article-title":"Lipid from electronic cigarette-aerosol both with and without nicotine induced pro-inflammatory macrophage polarization and disrupted phagocytosis","volume":"20","author":"Rahman","year":"2023","journal-title":"J. Inflamm. (Lond)"},{"key":"10.1016\/j.tiv.2026.106199_bb0180","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1002\/jat.3799","article-title":"The toxic potential of a fourth-generation E-cigarette on human lung cell lines and tissue explants","volume":"39","author":"Rankin","year":"2019","journal-title":"J. Appl. Toxicol."},{"issue":"5","key":"10.1016\/j.tiv.2026.106199_bb0185","doi-asserted-by":"crossref","first-page":"L557","DOI":"10.1152\/ajplung.00453.2021","article-title":"Nicotine aerosols diminish airway CFTR function and mucociliary clearance","volume":"324","author":"Rasmussen","year":"2023","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"issue":"6","key":"10.1016\/j.tiv.2026.106199_bb0190","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00951-2022","article-title":"Nicotine promotes e-cigarette vapour-induced lung inflammation and structural alterations","volume":"61","author":"Roxlau","year":"2023","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.tiv.2026.106199_bb0195","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1136\/tobaccocontrol-2018-054419","article-title":"Heat-not-burn tobacco products: a systematic literature review","volume":"28","author":"Simonavicius","year":"2019","journal-title":"Tob. Control"},{"key":"10.1016\/j.tiv.2026.106199_bb0200","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s00428-020-02943-0","article-title":"Vaping-related lung injury","volume":"478","author":"Smith","year":"2021","journal-title":"Virchows Arch."},{"key":"10.1016\/j.tiv.2026.106199_bb0205","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.healthpol.2021.02.003","article-title":"Emerging electronic cigarette policies in European member states, Canada, and the United States","volume":"125","author":"Snell","year":"2021","journal-title":"Health Policy"},{"issue":"6","key":"10.1016\/j.tiv.2026.106199_bb0210","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1021\/acs.chemrestox.8b00400","article-title":"Hydroxyl radicals in E-cigarette vapor and E-vapor oxidative potentials under different vaping patterns","volume":"32","author":"Son","year":"2019","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tiv.2026.106199_bb0215","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph191710528","article-title":"Challenges in predicting the change in the cumulative exposure of new tobacco and related products based on emissions and toxicity dose-response data","volume":"19","author":"Staal","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.tiv.2026.106199_bb0220","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12931-018-0778-z","article-title":"Altered lung biology of healthy never smokers following acute inhalation of E-cigarettes","volume":"19","author":"Staudt","year":"2018","journal-title":"Respir. Res."},{"key":"10.1016\/j.tiv.2026.106199_bb0225","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1136\/tobaccocontrol-2017-053808","article-title":"Comparing the cancer potencies of emissions from vapourised nicotine products including E-cigarettes with those of tobacco smoke","volume":"27","author":"Stephens","year":"2018","journal-title":"Tob. Control"},{"key":"10.1016\/j.tiv.2026.106199_bb0230","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1080\/15376516.2021.1884922","article-title":"Review of data on chemical content in an aerosol resulting from heating a tobacco or a solution used in e-cigarettes and in the smoke generated from the reference cigarettes","volume":"31","author":"Szparaga","year":"2021","journal-title":"Toxicol. Mech. Methods"},{"key":"10.1016\/j.tiv.2026.106199_bb0235","doi-asserted-by":"crossref","first-page":"22111","DOI":"10.1021\/acsomega.2c01527","article-title":"Should IQOS emissions be considered as smoke and harmful to health? A review of the chemical evidence","volume":"7","author":"Uguna","year":"2022","journal-title":"ACS Omega"},{"key":"10.1016\/j.tiv.2026.106199_bb0240","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0234189","article-title":"Electronic nicotine delivery system design and aerosol toxicants: a systematic review","volume":"15","author":"Ward","year":"2020","journal-title":"PloS One"},{"key":"10.1016\/j.tiv.2026.106199_bb0245","series-title":"WHO Global Report on Trends in Prevalence of Tobacco Use 2000\u20132025","year":"2021"},{"issue":"26","key":"10.1016\/j.tiv.2026.106199_bb0250","doi-asserted-by":"crossref","first-page":"4360","DOI":"10.1016\/j.atmosenv.2011.05.049","article-title":"Characterization of the size-distribution of aerosols and particle-bound content of oxygenated PAHs, PAHs, and n-alkanes in urban environments in Afghanistan","volume":"45","author":"Wingfors","year":"2011","journal-title":"Atmos. Environ."},{"key":"10.1016\/j.tiv.2026.106199_bb0255","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s13105-016-0465-9","article-title":"Tobacco nitrosamines as culprits in disease: mechanisms reviewed","volume":"72","author":"Yalcin","year":"2016","journal-title":"J. Physiol. Biochem."},{"key":"10.1016\/j.tiv.2026.106199_bb0260","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph18126651","article-title":"Exposure to heated tobacco products and adverse health effects, a systematic review","volume":"18","author":"Znyk","year":"2021","journal-title":"Int. J. Environ. Res. Public Health"}],"container-title":["Toxicology in Vitro"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088723332600007X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088723332600007X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T15:56:33Z","timestamp":1770220593000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S088723332600007X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":54,"alternative-id":["S088723332600007X"],"URL":"https:\/\/doi.org\/10.1016\/j.tiv.2026.106199","relation":{},"ISSN":["0887-2333"],"issn-type":[{"value":"0887-2333","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chemical characterisation and cytotoxic analysis of an electronic cigarette and heated tobacco product compared to a conventional cigarette in human lung cell lines","name":"articletitle","label":"Article Title"},{"value":"Toxicology in Vitro","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tiv.2026.106199","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"106199"}}