{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T02:12:04Z","timestamp":1788487924163,"version":"build-2803163510"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010581","name":"State Administration for Market Regulation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010581","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology in Vitro"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.tiv.2026.106267","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T23:29:04Z","timestamp":1780961344000},"page":"106267","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Multi-endpoint in vitro toxicity profiling of heated tobacco products versus e-cigarettes under air-liquid interface exposure"],"prefix":"10.1016","volume":"116","author":[{"given":"Hongjuan","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yushan","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peizhen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ningning","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaning","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shulei","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tiv.2026.106267_bb0005","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1016\/j.tiv.2015.06.016","article-title":"Evaluation of an air-liquid interface cell culture model for studies on the inflammatory and cytotoxic responses to tobacco smoke aerosols","volume":"29","author":"Azzopardi","year":"2015","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.tiv.2026.106267_bb0010","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1177\/026119291704500305","article-title":"In vitro exposure systems and dosimetry assessment tools for inhaled tobacco products: workshop proceedings, conclusions and paths forward for in vitro model use","volume":"45","author":"Behrsing","year":"2017","journal-title":"Altern. Lab. Anim"},{"key":"10.1016\/j.tiv.2026.106267_bb0015","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.toxlet.2020.10.005","article-title":"Optimization of aqueous aerosol extract (AqE) generation from e-cigarettes and tobacco heating products for in vitro cytotoxicity testing","volume":"335","author":"Bozhilova","year":"2020","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.tiv.2026.106267_bb0020","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.fct.2017.05.023","article-title":"A novel hybrid tobacco product that delivers a tobacco flavour note with vapour aerosol (part 2): in vitro biological assessment and comparison with different tobacco-heating products","volume":"106","author":"Breheny","year":"2017","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.tiv.2026.106267_bb0025","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/nyas.12977","article-title":"Electronic cigarettes: what are they and what do they do?","volume":"1394","author":"Breland","year":"2017","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.tiv.2026.106267_bb0030","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/j.cub.2015.03.008","article-title":"Molecular signatures of major depression","volume":"25","author":"Cai","year":"2015","journal-title":"Curr. Biol."},{"key":"10.1016\/j.tiv.2026.106267_bb0035","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1021\/acs.chemrestox.1c00309","article-title":"Formation of redox-active Duroquinone from vaping of vitamin E acetate contributes to oxidative lung injury","volume":"35","author":"Canchola","year":"2022","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tiv.2026.106267_bb0040","first-page":"182","article-title":"Induction of cytotoxicity,inflammatory factor release and apoptosis by cigarettes with different tar releases","volume":"32","author":"Chenfeng","year":"2020","journal-title":"Cancer\u00b7Aberration\u00b7Mutation"},{"key":"10.1016\/j.tiv.2026.106267_bb0045","doi-asserted-by":"crossref","DOI":"10.1186\/s12931-025-03302-w","article-title":"Unflavored electronic cigarette exposure induces alterations in airway ciliary structure and function","volume":"26","author":"Durra","year":"2025","journal-title":"Respir. Res."},{"key":"10.1016\/j.tiv.2026.106267_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.123417","article-title":"Comparison of the chemical composition of aerosols from heated tobacco products, electronic cigarettes and tobacco cigarettes and their toxic impacts on the human bronchial epithelial BEAS-2B cells","volume":"401","author":"Dusautoir","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.tiv.2026.106267_bb0055","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1021\/acs.chemrestox.9b00490","article-title":"In vitro toxicity and chemical characterization of aerosol derived from electronic cigarette humectants using a newly developed exposure system","volume":"33","author":"Escobar","year":"2020","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tiv.2026.106267_bb0060","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.yrtph.2017.10.006","article-title":"Assessment of novel tobacco heating product THP1.0. Part 3: comprehensive chemical characterisation of harmful and potentially harmful aerosol emissions","volume":"93","author":"Forster","year":"2018","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.tiv.2026.106267_bb0065","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s00424-023-02809-9","article-title":"Comparative study of the effects of cigarette smoke versus next-generation tobacco and nicotine product extracts on inflammatory biomarkers of human monocytes","volume":"475","author":"Giebe","year":"2023","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.tiv.2026.106267_bb0070","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1021\/acs.chemrestox.5b00321","article-title":"In vitro systems toxicology assessment of a candidate modified risk tobacco product shows reduced toxicity compared to that of a conventional cigarette","volume":"29","author":"Gonzalez-Suarez","year":"2016","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tiv.2026.106267_bb0075","first-page":"1","article-title":"Establishing an air-liquid interface exposure system for exposure of lung cells to gases","author":"Gu\u00e9nette","year":"2022","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.tiv.2026.106267_bb0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.yrtph.2017.08.006","article-title":"Comparative assessment of HPHC yields in the tobacco heating system THS2.2 and commercial cigarettes","volume":"90","author":"Jaccard","year":"2017","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.tiv.2026.106267_bb0085","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.yrtph.2017.09.016","article-title":"Assessment of tobacco heating product THP1.0. Part 5: in vitro dosimetric and cytotoxic assessment","volume":"93","author":"Jaunky","year":"2018","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.tiv.2026.106267_bb0090","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1016\/j.toxrep.2022.11.001","article-title":"Characterization of smoke and aerosol deliveries from combustible cigarettes, heated tobacco products and electronic nicotine delivery systems in the Vitrocell\u00ae mammalian 6\/48 exposure module","volume":"9","author":"Keyser","year":"2022","journal-title":"Toxicol. Rep."},{"key":"10.1016\/j.tiv.2026.106267_bb0095","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.tiv.2012.08.030","article-title":"Validation of an in vitro exposure system for toxicity assessment of air-delivered nanomaterials","volume":"27","author":"Kim","year":"2013","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.tiv.2026.106267_bb0100","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1089\/aivt.2017.0034","article-title":"Air-liquid Interface in vitro models for respiratory toxicology research: consensus workshop and recommendations","volume":"4","author":"Lacroix","year":"2018","journal-title":"Appl. In Vitro Toxicol."},{"key":"10.1016\/j.tiv.2026.106267_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2023.114866","article-title":"Air-liquid interface cultures to model drug delivery through the mucociliary epithelial barrier","volume":"198","author":"Lee","year":"2023","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.tiv.2026.106267_bb0110","doi-asserted-by":"crossref","DOI":"10.3390\/toxics12020128","article-title":"Metabolomics provides novel insights into the potential toxicity associated with heated tobacco products, electronic cigarettes, and tobacco cigarettes on human bronchial epithelial BEAS-2B cells","volume":"12","author":"Lenski","year":"2024","journal-title":"Toxics"},{"key":"10.1016\/j.tiv.2026.106267_bb0115","doi-asserted-by":"crossref","DOI":"10.1186\/1743-8977-6-32","article-title":"A dose-controlled system for air-liquid interface cell exposure and application to zinc oxide nanoparticles","volume":"6","author":"Lenz","year":"2009","journal-title":"Part. Fibre Toxicol."},{"key":"10.1016\/j.tiv.2026.106267_bb0120","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.tiv.2016.07.019","article-title":"In vitro toxicity testing of cigarette smoke based on the air-liquid interface exposure: a review","volume":"36","author":"Li","year":"2016","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.tiv.2026.106267_bb0125","doi-asserted-by":"crossref","DOI":"10.1002\/bmc.4634","article-title":"Simultaneous determination of plasma nicotine and cotinine by UHPLC-MS\/MS in C57BL\/6 mice and its application in a pharmacokinetic study","volume":"33","author":"Liu","year":"2019","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.tiv.2026.106267_bb0130","article-title":"E-cigarette market proportion by nicotine claims in the United States","volume":"54","author":"Ma","year":"2025","journal-title":"Prev. Med. Rep."},{"key":"10.1016\/j.tiv.2026.106267_bb0135","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1021\/acs.chemrestox.6b00188","article-title":"Chemical composition of aerosol from an E-cigarette: a quantitative comparison with cigarette smoke","volume":"29","author":"Margham","year":"2016","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tiv.2026.106267_bb0140","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.yrtph.2017.09.008","article-title":"Assessing modified risk tobacco and nicotine products: description of the scientific framework and assessment of a closed modular electronic cigarette","volume":"90","author":"Murphy","year":"2017","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.tiv.2026.106267_bb0145","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/cpdd.1322","article-title":"A randomized control study in healthy adult smokers to assess reduced exposure to selected cigarette smoke constituents in switching to the novel heated tobacco product DT3.0a","volume":"13","author":"Nishihara","year":"2024","journal-title":"Clin. Pharmacol. Drug Dev."},{"key":"10.1016\/j.tiv.2026.106267_bb0150","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.radonc.2011.05.055","article-title":"Retention of \u03b3H2AX foci as an indication of lethal DNA damage","volume":"101","author":"Olive","year":"2011","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.tiv.2026.106267_bb0155","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1080\/19768354.2021.1915380","article-title":"The anti-cancer effect of betulinic acid in u937 human leukemia cells is mediated through ROS-dependent cell cycle arrest and apoptosis","volume":"25","author":"Park","year":"2021","journal-title":"Anim. Cells Syst. (Seoul)"},{"key":"10.1016\/j.tiv.2026.106267_bb0160","series-title":"In-Vitro Cell Exposure Studies for the Assessment of Nanoparticle Toxicity in the Lung: A Dialog Between Aeerosol Science and Biology","author":"Paur","year":"2011"},{"issue":"Suppl. 2","key":"10.1016\/j.tiv.2026.106267_bb0165","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1016\/j.yrtph.2016.10.001","article-title":"Evaluation of the tobacco heating system 2.2. Part 2: chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol","volume":"81","author":"Schaller","year":"2016","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.tiv.2026.106267_bb0170","doi-asserted-by":"crossref","DOI":"10.1186\/s12974-026-03712-7","article-title":"Heated tobacco and cigarette smoke modulate CD4+ T cell activation and neuroinflammation in a context-dependent manner","volume":"23","author":"Scharf","year":"2026","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.tiv.2026.106267_bb0175","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/978-1-0716-2364-0_10","article-title":"Human bronchial epithelial cell culture models for cigarette smoke and vaping studies","volume":"2506","author":"Schaunaman","year":"2022","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.tiv.2026.106267_bb0180","doi-asserted-by":"crossref","first-page":"3915","DOI":"10.3390\/ijerph120403915","article-title":"Evaluation of E-cigarette liquid vapor and mainstream cigarette smoke after direct exposure of primary human bronchial epithelial cells","volume":"12","author":"Scheffler","year":"2015","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.tiv.2026.106267_bb0185","series-title":"A Comparison of Accelerated Solvent Extraction, Soxhlet Extraction, and Ultrasonic-Assisted Extraction for Analysis of Terpenoids and Sterols in Tobacco","first-page":"1003","volume":"383","author":"Shen","year":"2005"},{"key":"10.1016\/j.tiv.2026.106267_bb0190","article-title":"Heated tobacco products for smoking cessation and reducing smoking prevalence","volume":"1","author":"Tattan-Birch","year":"2022","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.tiv.2026.106267_bb0195","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.yrtph.2017.08.016","article-title":"Assessment of novel tobacco heating product THP1.0. Part 6: a comparative in vitro study using contemporary screening approaches","volume":"93","author":"Taylor","year":"2018","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.tiv.2026.106267_bb0200","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/j.etp.2013.06.001","article-title":"A review of in vitro cigarette smoke exposure systems","volume":"65","author":"Thorne","year":"2013","journal-title":"Exp. Toxicol. Pathol."},{"key":"10.1016\/j.tiv.2026.106267_bb0205","doi-asserted-by":"crossref","first-page":"629","DOI":"10.3109\/08958378.2015.1080773","article-title":"A comparative assessment of cigarette smoke aerosols using an in vitro air-liquid interface cytotoxicity test","volume":"27","author":"Thorne","year":"2015","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.tiv.2026.106267_bb0210","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.toxlet.2016.12.006","article-title":"The comparative in vitro assessment of e-cigarette and cigarette smoke aerosols using the \u03b3H2AX assay and applied dose measurements","volume":"265","author":"Thorne","year":"2017","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.tiv.2026.106267_bb0215","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.toxrep.2020.08.013","article-title":"The genotoxicological assessment of a tobacco heating product relative to cigarette smoke using the in vitro micronucleus assay","volume":"7","author":"Thorne","year":"2020","journal-title":"Toxicol. Rep."},{"key":"10.1016\/j.tiv.2026.106267_bb0220","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.lfs.2016.12.009","article-title":"3\u2019-Hydroxy-4\u2032-methoxy-\u03b2-methyl-\u03b2-nitrostyrene inhibits tumor growth through ROS generation and GSH depletion in lung cancer cells","volume":"172","author":"Tsai","year":"2017","journal-title":"Life Sci."},{"key":"10.1016\/j.tiv.2026.106267_bb0225","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1093\/toxsci\/kfy053","article-title":"Air-liquid Interface: relevant in vitro models for investigating air pollutant-induced pulmonary toxicity","volume":"164","author":"Upadhyay","year":"2018","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tiv.2026.106267_bb0230","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.toxlet.2020.06.017","article-title":"Harmful chemicals of heat not burn product and its induced oxidative stress of macrophages at air-liquid interface: comparison with ultra-light cigarette","volume":"331","author":"Wang","year":"2020","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.tiv.2026.106267_bb0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.tiv.2021.105173","article-title":"In vitro toxicological evaluation of a tobacco heating product THP COO and 3R4F research reference cigarette on human lung cancer cells","volume":"74","author":"Wang","year":"2021","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.tiv.2026.106267_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.tiv.2020.104866","article-title":"A comparative in vitro toxicity assessment of electronic vaping product e-liquids and aerosols with tobacco cigarette smoke","volume":"66","author":"Wieczorek","year":"2020","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.tiv.2026.106267_bb0245","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.envpol.2017.04.080","article-title":"The use of a 0.20 \u03bcm particulate matter filter decreases cytotoxicity in lung epithelial cells following air-liquid interface exposure to motorcycle exhaust","volume":"227","author":"Yu","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.tiv.2026.106267_bb0250","doi-asserted-by":"crossref","DOI":"10.3390\/toxics11100847","article-title":"Impact of electronic cigarettes, heated tobacco products and conventional cigarettes on the generation of oxidative stress and genetic and epigenetic lesions in human bronchial epithelial BEAS-2B cells","volume":"11","author":"Zarcone","year":"2023","journal-title":"Toxics"},{"key":"10.1016\/j.tiv.2026.106267_bb0255","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1039\/C7TX00109F","article-title":"Regulating temperature and relative humidity in air-liquid interface in vitro systems eliminates cytotoxicity resulting from control air exposures","volume":"6","author":"Zavala","year":"2017","journal-title":"Toxicol. Res. (Camb.)"},{"key":"10.1016\/j.tiv.2026.106267_bb0260","doi-asserted-by":"crossref","DOI":"10.1186\/s12302-025-01258-8","article-title":"Next-generation high-throughput in vitro exposure system for early hazard ranking and comparative assessment of cigarette smoke and heated tobacco aerosols","volume":"37","author":"Zimmermann-Klemd","year":"2025","journal-title":"Environ. Sci. Eur."}],"container-title":["Toxicology in Vitro"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0887233326000755?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0887233326000755?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T01:14:07Z","timestamp":1788484447000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0887233326000755"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":52,"alternative-id":["S0887233326000755"],"URL":"https:\/\/doi.org\/10.1016\/j.tiv.2026.106267","relation":{},"ISSN":["0887-2333"],"issn-type":[{"value":"0887-2333","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multi-endpoint in vitro toxicity profiling of heated tobacco products versus e-cigarettes under air-liquid interface exposure","name":"articletitle","label":"Article Title"},{"value":"Toxicology in Vitro","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tiv.2026.106267","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106267"}}