{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:39:27Z","timestamp":1787791167655,"version":"build-2784847793"},"reference-count":86,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.tjnut.2023.09.012","type":"journal-article","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T04:38:46Z","timestamp":1694752726000},"page":"3327-3340","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["L-arabinose Attenuates LPS-Induced Intestinal Inflammation and Injury through Reduced M1 Macrophage Polarization"],"prefix":"10.1016","volume":"153","author":[{"given":"Luyuan","family":"Kang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaman","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yisi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6041-4887","authenticated-orcid":false,"given":"Dandan","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tjnut.2023.09.012_bib1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3389\/fimmu.2019.00049","article-title":"Multidrug-resistant pseudomonas aeruginosa accelerate intestinal, extra-intestinal, and systemic inflammatory responses in human microbiota-associated mice with subacute ileitis","volume":"10","author":"Heimesaat","year":"2019","journal-title":"Front. Immunol."},{"issue":"12","key":"10.1016\/j.tjnut.2023.09.012_bib2","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1038\/nrgastro.2015.150","article-title":"The global burden of IBD: from 2015 to 2025","volume":"12","author":"Kaplan","year":"2015","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S2468-1253(19)30333-4","article-title":"GBD 2017 Inflammatory Bowel Disease Collaborators, The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990\u20132017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"5","year":"2020","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"10.1016\/j.tjnut.2023.09.012_bib4","first-page":"558","article-title":"The role of infection in inflammatory bowel disease: initiation, exacerbation and protection","volume":"9","author":"Lidar","year":"2009","journal-title":"Israeli Med. Assoc. J."},{"issue":"6917","key":"10.1016\/j.tjnut.2023.09.012_bib5","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/nature01326","article-title":"The immunopathogenesis of sepsis","volume":"420","author":"Cohen","year":"2002","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.tjnut.2023.09.012_bib6","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1038\/s41590-019-0368-3","article-title":"Innate immunity to intracellular LPS","volume":"20","author":"Rathinam","year":"2019","journal-title":"Nat. Immunol."},{"issue":"11","key":"10.1016\/j.tjnut.2023.09.012_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jas\/skab296","article-title":"Bisdemethoxycurcumin attenuates lipopolysaccharide-induced intestinal damage through improving barrier integrity, suppressing inflammation, and modulating gut microbiota in broilers","volume":"99","author":"Zhang","year":"2021","journal-title":"J.\u00a0Anim. Sci."},{"issue":"22","key":"10.1016\/j.tjnut.2023.09.012_bib8","doi-asserted-by":"crossref","first-page":"11811","DOI":"10.1039\/D2FO02598A","article-title":"Curcumin alleviates LPS-induced intestinal homeostatic imbalance through reshaping gut microbiota structure and regulating group 3 innate lymphoid cells in chickens","volume":"13","author":"Ruan","year":"2022","journal-title":"Food Funct"},{"issue":"2","key":"10.1016\/j.tjnut.2023.09.012_bib9","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1039\/C4FO00638K","article-title":"The effect of low or high molecular weight oat beta-glucans on the inflammatory and oxidative stress status in the colon of rats with LPS-induced enteritis","volume":"6","author":"Wilczak","year":"2015","journal-title":"Food Funct"},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib10","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3382\/ps.2009-00243","article-title":"The effects of berberine on the magnitude of the acute inflammatory response induced by Escherichia coli lipopolysaccharide in broiler chickens","volume":"89","author":"Shen","year":"2010","journal-title":"Poult. Sci."},{"issue":"11","key":"10.1016\/j.tjnut.2023.09.012_bib11","doi-asserted-by":"crossref","first-page":"5389","DOI":"10.1016\/j.psj.2020.08.007","article-title":"Effects of dietary pyrroloquinoline quinone disodium supplementation on inflammatory responses, oxidative stress, and intestinal morphology in broiler chickens challenged with lipopolysaccharide","volume":"99","author":"Zheng","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.tjnut.2023.09.012_bib12","doi-asserted-by":"crossref","first-page":"718356","DOI":"10.3389\/fnut.2021.718356","article-title":"Inflammatory and microbiota-related regulation of the intestinal epithelial barrier","volume":"8","author":"Barbara","year":"2021","journal-title":"Front. Nutr."},{"issue":"2","key":"10.1016\/j.tjnut.2023.09.012_bib13","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/path.4133","article-title":"Macrophage plasticity and polarization in tissue repair and remodelling","volume":"229","author":"Mantovani","year":"2013","journal-title":"J.\u00a0Pathol."},{"issue":"9","key":"10.1016\/j.tjnut.2023.09.012_bib14","doi-asserted-by":"crossref","first-page":"6425","DOI":"10.1002\/jcp.26429","article-title":"Macrophage plasticity, polarization, and function in health and disease","volume":"233","author":"Shapouri","year":"2018","journal-title":"J.\u00a0Cell Physiol."},{"key":"10.1016\/j.tjnut.2023.09.012_bib15","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1146\/annurev-physiol-022516-034339","article-title":"Macrophage polarization","volume":"79","author":"Murray","year":"2017","journal-title":"Annu. Rev. Physiol."},{"issue":"21","key":"10.1016\/j.tjnut.2023.09.012_bib16","doi-asserted-by":"crossref","first-page":"4111","DOI":"10.1007\/s00018-015-1995-y","article-title":"Macrophage polarization in pathology","volume":"72","author":"Sica","year":"2015","journal-title":"Cell Mol. Life Sci."},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00011-015-0874-1","article-title":"Macrophage polarization: the link between inflammation and related diseases","volume":"65","author":"Bashir","year":"2016","journal-title":"Inflamm. Res."},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib18","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.immuni.2014.06.008","article-title":"Macrophage activation and polarization: nomenclature and experimental guidelines","volume":"41","author":"Murray","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.tjnut.2023.09.012_bib19","doi-asserted-by":"crossref","first-page":"514","DOI":"10.3389\/fimmu.2014.00514","article-title":"From monocytes to M1\/M2 macrophages: phenotypical vs. functional differentiation","volume":"5","author":"Italiani","year":"2014","journal-title":"Front. Immunol."},{"issue":"11","key":"10.1016\/j.tjnut.2023.09.012_bib20","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/nri3073","article-title":"Protective and pathogenic functions of macrophage subsets","volume":"11","author":"Murray","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.tjnut.2023.09.012_bib21","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3389\/fimmu.2018.00087","article-title":"Control of intestinal inflammation, colitis-associated tumorigenesis, and macrophage polarization by fibrinogen-like protein 2","volume":"9","author":"Zhu","year":"2018","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.tjnut.2023.09.012_bib22","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/cmi.2014.15","article-title":"Chemerin aggravates DSS-induced colitis by suppressing M2 macrophage polarization","volume":"11","author":"Lin","year":"2014","journal-title":"Cell Mol. Immunol."},{"issue":"4","key":"10.1016\/j.tjnut.2023.09.012_bib23","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/imm.12741","article-title":"Ficolin-A\/2, acting as a new regulator of macrophage polarization, mediates the inflammatory response in experimental mouse colitis","volume":"151","author":"Yang","year":"2017","journal-title":"Immunology"},{"issue":"6","key":"10.1016\/j.tjnut.2023.09.012_bib24","first-page":"1297","article-title":"Monocyte and M1 macrophage-induced barrier defect contributes to chronic intestinal inflammation in IBD","volume":"21","author":"Lissner","year":"2015","journal-title":"Inflamm. Bowel Dis."},{"issue":"11","key":"10.1016\/j.tjnut.2023.09.012_bib25","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1093\/intimm\/dxy054","article-title":"Macrophages in inflammation, repair and regeneration","volume":"30","author":"Oishi","year":"2018","journal-title":"Int. Immunol."},{"issue":"2","key":"10.1016\/j.tjnut.2023.09.012_bib26","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1039\/C2FO30156C","article-title":"Characterization of polarized THP-1 macrophages and polarizing ability of LPS and food compounds","volume":"4","author":"Chanput","year":"2013","journal-title":"Food Funct"},{"issue":"8","key":"10.1016\/j.tjnut.2023.09.012_bib27","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.3390\/molecules23081880","article-title":"Decursinol angelate inhibits LPS-induced macrophage polarization through modulation of the NF\u03baB and MAPK signaling pathways","volume":"23","author":"Islam","year":"2018","journal-title":"Molecules"},{"issue":"15","key":"10.1016\/j.tjnut.2023.09.012_bib28","doi-asserted-by":"crossref","first-page":"7856","DOI":"10.3390\/ijms22157856","article-title":"Histatin-1 attenuates LPS-induced inflammatory signaling in RAW264.7 macrophages","volume":"22","author":"Lee","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.tjnut.2023.09.012_bib29","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1080\/07328303.2018.1491049","article-title":"Novel approaches for biotechnological production and application of L-arabinose","volume":"37","author":"Feh\u00e9r","year":"2018","journal-title":"J.\u00a0Carbohydr. Chem."},{"issue":"4","key":"10.1016\/j.tjnut.2023.09.012_bib30","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1039\/D0FO02163F","article-title":"L-arabinose suppresses gluconeogenesis through modulating AMP-activated protein kinase in metabolic disorder mice","volume":"12","author":"Wang","year":"2021","journal-title":"Food Funct"},{"issue":"12","key":"10.1016\/j.tjnut.2023.09.012_bib31","doi-asserted-by":"crossref","first-page":"3054","DOI":"10.3390\/nu11123054","article-title":"L-arabinose elicits gut-derived hydrogen production and ameliorates metabolic syndrome in C57BL\/6J mice on high-fat-diet","volume":"11","author":"Zhao","year":"2019","journal-title":"Nutrients"},{"issue":"12","key":"10.1016\/j.tjnut.2023.09.012_bib32","doi-asserted-by":"crossref","first-page":"3638","DOI":"10.1021\/acs.jafc.0c07167","article-title":"L-arabinose attenuates gliadin-induced food allergy via regulation of Th1\/Th2 balance and upregulation of regulatory T cells in mice","volume":"69","author":"Wang","year":"2021","journal-title":"J.\u00a0Agric. Food Chem."},{"issue":"48","key":"10.1016\/j.tjnut.2023.09.012_bib33","doi-asserted-by":"crossref","first-page":"13299","DOI":"10.1021\/acs.jafc.9b05829","article-title":"L-arabinose inhibits colitis by modulating gut microbiota in mice","volume":"67","author":"Li","year":"2019","journal-title":"J.\u00a0Agric. Food Chem."},{"issue":"3","key":"10.1016\/j.tjnut.2023.09.012_bib34","doi-asserted-by":"crossref","first-page":"111087","DOI":"10.1016\/j.celrep.2022.111087","article-title":"Cooperative action of gut-microbiota-accessible carbohydrates improves host metabolic function","volume":"40","author":"Tomioka","year":"2022","journal-title":"Cell Rep"},{"issue":"3","key":"10.1016\/j.tjnut.2023.09.012_bib35","doi-asserted-by":"crossref","first-page":"59","DOI":"10.12938\/bmfh.31.59","article-title":"Effect of dietary L-arabinose on the intestinal microbiota and metabolism of dietary daidzein in adult mice","volume":"31","author":"Tamura","year":"2012","journal-title":"Biosci. Microbiota Food Health."},{"key":"10.1016\/j.tjnut.2023.09.012_bib36","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1080\/00071669208417446","article-title":"Nutritional value of D-xylose and L-arabinose for broiler chicks","volume":"33","author":"Schutte","year":"1992","journal-title":"Br. Poult. Sci."},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib37","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s40168-022-01458-x","article-title":"Gut microbiota-derived ursodeoxycholic acid alleviates low birth weight-induced colonic inflammation by enhancing M2 macrophage polarization","volume":"11","author":"Pi","year":"2023","journal-title":"Microbiome"},{"key":"10.1016\/j.tjnut.2023.09.012_bib38","article-title":"Strain specificity of lactobacilli with promoted colonization by galactooligosaccharides administration in protecting intestinal barriers during Salmonella infection","author":"Wu","year":"2023","journal-title":"J.\u00a0Adv. Res."},{"key":"10.1016\/j.tjnut.2023.09.012_bib39","article-title":"Bacillus coagulans TL3 inhibits LPS-induced caecum damage in rat by regulating the TLR4\/MyD88\/NF-\u03baB and Nrf2 signal pathways and modulating intestinal microflora","volume":"2022","author":"Wang","year":"2022","journal-title":"Oxid. Med. Cell Longev."},{"key":"10.1016\/j.tjnut.2023.09.012_bib40","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/4876078","article-title":"Milk fat globule membrane supplementation promotes neonatal growth and alleviates inflammation in low-birth-weight mice treated with lipopolysaccharide","volume":"2019","author":"Huang","year":"2019","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.tjnut.2023.09.012_bib41","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/0034-5288(93)90038-H","article-title":"Villus height and crypt depth in weaned and unweaned pigs, reared under various circumstances in the Netherlands","volume":"53","author":"Nabuurs","year":"1993","journal-title":"Res. Veterinal Sci."},{"key":"10.1016\/j.tjnut.2023.09.012_bib42","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.dib.2015.09.029","article-title":"Differential expression patterns of Nqo1, AKR1B8 and Ho-1 in the liver and small intestine of C57BL\/6 mice treated with sulforaphane","volume":"5","author":"Luo","year":"2015","journal-title":"Data Brief"},{"issue":"4","key":"10.1016\/j.tjnut.2023.09.012_bib43","doi-asserted-by":"crossref","first-page":"46","DOI":"10.5409\/wjcp.v2.i4.46","article-title":"Bacterial colonization and intestinal mucosal barrier development","volume":"2","author":"Huang","year":"2013","journal-title":"World J. Clin. Pediatr."},{"issue":"9","key":"10.1016\/j.tjnut.2023.09.012_bib44","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1016\/j.immuni.2022.08.005","article-title":"Macrophages in the gut: masters in multitasking","volume":"55","author":"Delfini","year":"2022","journal-title":"Immunity"},{"issue":"24","key":"10.1016\/j.tjnut.2023.09.012_bib45","doi-asserted-by":"crossref","first-page":"9517","DOI":"10.1073\/pnas.1119038109","article-title":"Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization","volume":"109","author":"Arranz","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA."},{"issue":"3","key":"10.1016\/j.tjnut.2023.09.012_bib46","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.cgh.2006.12.009","article-title":"Gut microbiota: mining for therapeutic potential","volume":"5","author":"O'Hara","year":"2007","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.tjnut.2023.09.012_bib47","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.coi.2014.07.003","article-title":"The cross talk between microbiota and the immune system: metabolites take center stage","volume":"30","author":"Shapiro","year":"2014","journal-title":"Curr. Opin. Immunol."},{"issue":"14","key":"10.1016\/j.tjnut.2023.09.012_bib48","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1101\/gad.284091.116","article-title":"Metabolites: messengers between the microbiota and the immune system","volume":"30","author":"Levy","year":"2016","journal-title":"Genes Dev"},{"issue":"22","key":"10.1016\/j.tjnut.2023.09.012_bib49","doi-asserted-by":"crossref","first-page":"6949","DOI":"10.3390\/molecules26226949","article-title":"Quercetin prevents LPS-induced oxidative stress and inflammation by modulating NOX2\/ROS\/NF-kB in lung epithelial cells","volume":"26","author":"Sul","year":"2021","journal-title":"Molecules"},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib50","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s12967-021-02745-1","article-title":"Panaxydol attenuates ferroptosis against LPS-induced acute lung injury in mice by Keap1-Nrf2\/HO-1 pathway","volume":"19","author":"Li","year":"2021","journal-title":"J.\u00a0Transl. Med."},{"issue":"2","key":"10.1016\/j.tjnut.2023.09.012_bib51","doi-asserted-by":"crossref","first-page":"9367","DOI":"10.1080\/21655979.2021.2001913","article-title":"Ferrostatin-1 alleviates lipopolysaccharide-induced cardiac dysfunction","volume":"12","author":"Xiao","year":"2021","journal-title":"Bioengineered"},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib52","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/labinvest.3700366","article-title":"Lipopolysaccharide signaling in endothelial cells","volume":"86","author":"Dauphinee","year":"2006","journal-title":"Lab Invest"},{"issue":"12","key":"10.1016\/j.tjnut.2023.09.012_bib53","doi-asserted-by":"crossref","DOI":"10.1111\/jfbc.13991","article-title":"Effects of L-arabinose by hypoglycemic and modulating gut microbiome in a high-fat diet- and streptozotocin-induced mouse model of type 2 diabetes mellitus","volume":"45","author":"Shen","year":"2021","journal-title":"J.\u00a0Food Biochem."},{"issue":"9","key":"10.1016\/j.tjnut.2023.09.012_bib54","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201700814","article-title":"Flaxseed oil attenuates intestinal damage and inflammation by regulating necroptosis and TLR4\/NOD signaling pathways following lipopolysaccharide challenge in a piglet model","volume":"62","author":"Zhu","year":"2018","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.tjnut.2023.09.012_bib55","doi-asserted-by":"crossref","first-page":"107272","DOI":"10.1016\/j.intimp.2020.107272","article-title":"Effect of gut microbiota on LPS-induced acute lung injury by regulating the TLR4\/NF-kB signaling pathway","volume":"91","author":"Tang","year":"2021","journal-title":"Int. Immunopharmacol."},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib56","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jaci.2009.05.038","article-title":"Intestinal barrier function: molecular regulation and disease pathogenesis","volume":"124","author":"Groschwitz","year":"2009","journal-title":"J.\u00a0Allergy Clin. Immunol."},{"issue":"4","key":"10.1016\/j.tjnut.2023.09.012_bib57","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/nrmicro2538","article-title":"Mucin dynamics and enteric pathogens","volume":"9","author":"McGuckin","year":"2011","journal-title":"Nat. Rev. Microbiol."},{"issue":"3","key":"10.1016\/j.tjnut.2023.09.012_bib58","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/mi.2008.5","article-title":"Mucins in the mucosal barrier to infection","volume":"1","author":"Linden","year":"2008","journal-title":"Mucosal. Immunol."},{"issue":"5","key":"10.1016\/j.tjnut.2023.09.012_bib59","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1136\/jcp.2003.013292","article-title":"MUC1 and MUC2 in pancreatic neoplasia","volume":"57","author":"Levi","year":"2004","journal-title":"J.\u00a0Clin. Pathol."},{"issue":"9","key":"10.1016\/j.tjnut.2023.09.012_bib60","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/nri.2017.52","article-title":"The non-canonical NF-\u03baB pathway in immunity and inflammation","volume":"17","author":"Sun","year":"2017","journal-title":"Nat. Rev. Immunol."},{"issue":"3","key":"10.1016\/j.tjnut.2023.09.012_bib61","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1097\/QCO.0b013e3282f88b5d","article-title":"Mycobacterial interaction with innate receptors: TLRs, C-type lectins, and NLRs","volume":"21","author":"Jo","year":"2008","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.tjnut.2023.09.012_bib62","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.arr.2017.02.004","article-title":"Targeting the TLR4 signaling pathway by polyphenols: a novel therapeutic strategy for neuroinflammation","volume":"36","author":"Rahimifard","year":"2017","journal-title":"Ageing Res. Rev."},{"issue":"9","key":"10.1016\/j.tjnut.2023.09.012_bib63","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1038\/labinvest.2010.85","article-title":"Cellular and molecular mechanisms regulating the hepatic erythropoietin expression during acute-phase response: a role for IL-6","volume":"90","author":"Ramadori","year":"2010","journal-title":"Lab. Invest."},{"key":"10.1016\/j.tjnut.2023.09.012_bib64","doi-asserted-by":"crossref","first-page":"9867150","DOI":"10.1155\/2018\/9867150","article-title":"Tanshinone IIA sodium sulfonate attenuates LPS-induced intestinal injury in mice","volume":"2018","author":"Yang","year":"2018","journal-title":"Gastroenterol. Res. Pract."},{"issue":"13","key":"10.1016\/j.tjnut.2023.09.012_bib65","doi-asserted-by":"crossref","first-page":"3328","DOI":"10.3390\/ijms20133328","article-title":"The NLRP3 inflammasome: an overview of mechanisms of activation and regulation","volume":"20","author":"Kelley","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"5963","key":"10.1016\/j.tjnut.2023.09.012_bib66","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1126\/science.1184003","article-title":"The NLRP3 inflammasome: a sensor for metabolic danger?","volume":"327","author":"Schroder","year":"2010","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.tjnut.2023.09.012_bib67","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.jhep.2016.12.018","article-title":"HBV inhibits LPS-induced NLRP3 inflammasome activation and IL-1beta production via suppressing the NF-\u03baB pathway and ROS production","volume":"66","author":"Yu","year":"2017","journal-title":"J.\u00a0Hepatol."},{"issue":"5","key":"10.1016\/j.tjnut.2023.09.012_bib68","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1002\/mnfr.201100715","article-title":"\u03b2-glucans are involved in immune-modulation of THP-1 macrophages","volume":"56","author":"Chanput","year":"2012","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.tjnut.2023.09.012_bib69","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2172-8-1","article-title":"Transcriptional profiling of the LPS induced NF-kappaB response in macrophages","volume":"8","author":"Sharif","year":"2007","journal-title":"BMC Immunol"},{"issue":"6","key":"10.1016\/j.tjnut.2023.09.012_bib70","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/S0091-6749(99)70189-2","article-title":"Increased expression of the CD80 accessory molecule by alveolar macrophages in asthmatic subjects and its functional involvement in allergen presentation to autologous TH2 lymphocytes","volume":"103","author":"Burastero","year":"1999","journal-title":"J.\u00a0Allergy Clin. Immun."},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib71","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.imbio.2017.10.005","article-title":"The impact of interferon-regulatory factors to macrophage differentiation and polarization into M1 and M2","volume":"223","author":"Chistiakov","year":"2018","journal-title":"Immunobiology"},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib72","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1089\/wound.2011.0307","article-title":"Regulation of macrophage polarization and wound healing","volume":"1","author":"Ferrante","year":"2012","journal-title":"Adv. Wound Care (New Rochelle)."},{"key":"10.1016\/j.tjnut.2023.09.012_bib73","doi-asserted-by":"crossref","first-page":"496","DOI":"10.5604\/17322693.1150133","article-title":"Different pathways of macrophage activation and polarization","volume":"69","author":"Juhas","year":"2015","journal-title":"Postepy Hig. Med. Dosw. (Online)."},{"issue":"4","key":"10.1016\/j.tjnut.2023.09.012_bib74","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.bbrc.2020.10.062","article-title":"TRPM7 modulates macrophage polarization by STAT1\/STAT6 pathways in RAW264.7 cells","volume":"533","author":"Li","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"13","key":"10.1016\/j.tjnut.2023.09.012_bib75","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1084\/jem.20061884","article-title":"Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement","volume":"203","author":"Chieppa","year":"2006","journal-title":"J.\u00a0Exp. Med."},{"issue":"5707","key":"10.1016\/j.tjnut.2023.09.012_bib76","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1126\/science.1102901","article-title":"CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance","volume":"307","author":"Niess","year":"2005","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.tjnut.2023.09.012_bib77","doi-asserted-by":"crossref","first-page":"G504","DOI":"10.1152\/ajpgi.00312.2011","article-title":"Berberine promotes recovery of colitis and inhibits inflammatory responses in colonic macrophages and epithelial cells in DSS-treated mice","volume":"302","author":"Yan","year":"2012","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"4","key":"10.1016\/j.tjnut.2023.09.012_bib78","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.cmet.2020.09.004","article-title":"The gut microbiota at the service of immunometabolism","volume":"32","author":"Michaudel","year":"2020","journal-title":"Cell Metab"},{"issue":"5","key":"10.1016\/j.tjnut.2023.09.012_bib79","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1002\/ptr.7429","article-title":"Anti-inflammatory effect of Rhein on ulcerative colitis via inhibiting PI3K\/Akt\/mTOR signaling pathway and regulating gut microbiota","volume":"36","author":"Dong","year":"2022","journal-title":"Phytother. Res."},{"issue":"4","key":"10.1016\/j.tjnut.2023.09.012_bib80","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/s41575-019-0258-z","article-title":"Gut microbiota-derived metabolites as key actors in inflammatory bowel disease","volume":"17","author":"Lavelle","year":"2020","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib81","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.2009.01514.x","article-title":"Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine","volume":"294","author":"Louis","year":"2009","journal-title":"FEMS Microbiol. Lett."},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib82","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1128\/CMR.00058-16","article-title":"Clinical and pathophysiological overview of acinetobacter infections: a century of challenges","volume":"30","author":"Wong","year":"2017","journal-title":"Clin. Microbiol. Rev."},{"issue":"3","key":"10.1016\/j.tjnut.2023.09.012_bib83","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1159\/000360010","article-title":"Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD","volume":"39","author":"Wong","year":"2014","journal-title":"Am. J. Nephrol."},{"key":"10.1016\/j.tjnut.2023.09.012_bib84","doi-asserted-by":"crossref","first-page":"821780","DOI":"10.3389\/fcimb.2022.821780","article-title":"Gut microbiome and metabolome changes in mice with acute vestibular deficit","volume":"12","author":"Li","year":"2022","journal-title":"Front. Cell Infect. Microbiol."},{"issue":"1","key":"10.1016\/j.tjnut.2023.09.012_bib85","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/mi.2014.44","article-title":"Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathway","volume":"8","author":"Park","year":"2015","journal-title":"Mucosal. Immunol."},{"issue":"5","key":"10.1016\/j.tjnut.2023.09.012_bib86","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.chom.2015.03.005","article-title":"Crosstalk between microbiota-derived short-chain fatty acids and intestinal epithelial HIF augments tissue barrier function","volume":"17","author":"Kelly","year":"2015","journal-title":"Cell Host. Microbe."}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623726072?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623726072?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T05:46:30Z","timestamp":1758347190000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316623726072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":86,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S0022316623726072"],"URL":"https:\/\/doi.org\/10.1016\/j.tjnut.2023.09.012","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"L-arabinose Attenuates LPS-Induced Intestinal Inflammation and Injury through Reduced M1 Macrophage Polarization","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjnut.2023.09.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American Society for Nutrition. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}