{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T18:13:05Z","timestamp":1790100785177,"version":"4.0.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.tjnut.2023.12.004","type":"journal-article","created":{"date-parts":[[2023,12,9]],"date-time":"2023-12-09T17:50:14Z","timestamp":1702144214000},"page":"535-542","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Lactobacillus amylovorus Promotes Lactose Utilization in Small Intestine and Enhances Intestinal Barrier Function in Intrauterine Growth Restricted Piglets"],"prefix":"10.1016","volume":"154","author":[{"given":"Yujun","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youwei","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinbiao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaolai","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9427-3824","authenticated-orcid":false,"given":"Junjun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tjnut.2023.12.004_bib1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4137\/CMPed.S40070","article-title":"Intrauterine growth restriction: antenatal and postnatal aspects","volume":"10","author":"Sharma","year":"2016","journal-title":"Clin. Med. Insights Pediatr."},{"issue":"9","key":"10.1016\/j.tjnut.2023.12.004_bib2","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1002\/mrd.22842","article-title":"Physiological alterations associated with intrauterine growth restriction in fetal pigs: causes and insights for nutritional optimization","volume":"84","author":"Wang","year":"2017","journal-title":"Mol. Reprod. Dev."},{"issue":"9","key":"10.1016\/j.tjnut.2023.12.004_bib3","doi-asserted-by":"crossref","first-page":"2316","DOI":"10.2527\/jas.2006-156","article-title":"Board-Invited Review: Intrauterine growth retardation: implications for the animal sciences","volume":"84","author":"Wu","year":"2006","journal-title":"J.\u00a0Anim. Sci."},{"key":"10.1016\/j.tjnut.2023.12.004_bib4","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/4876078","article-title":"Milk fat globule membrane supplementation promotes neonatal growth and alleviates inflammation in low-birth-weight mice treated with lipopolysaccharide","volume":"2019","author":"Huang","year":"2019","journal-title":"Biomed Res. Int."},{"key":"10.1016\/j.tjnut.2023.12.004_bib5","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1038\/nrgastro.2014.66","article-title":"Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic","volume":"11","author":"Hill","year":"2014","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.tjnut.2023.12.004_bib6","doi-asserted-by":"crossref","first-page":"797","DOI":"10.3389\/fmicb.2019.00797","article-title":"Characterization of the early life microbiota development and predominant Lactobacillus species at distinct gut segments of low- and normal-birth-weight piglets","volume":"10","author":"Li","year":"2019","journal-title":"Front. Microbiol."},{"issue":"4","key":"10.1016\/j.tjnut.2023.12.004_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0094891","article-title":"Lactobacillus amylovorus inhibits the TLR4 inflammatory signaling triggered by enterotoxigenic Escherichia coli via modulation of the negative regulators and involvement of TLR2 in intestinal Caco-2 cells and pig explants","volume":"9","author":"Finamore","year":"2014","journal-title":"PLOS ONE"},{"issue":"1","key":"10.1016\/j.tjnut.2023.12.004_bib8","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1186\/s12866-016-0847-8","article-title":"Differential protection by cell wall components of Lactobacillus amylovorus DSM 16698T against alterations of membrane barrier and NF-kB activation induced by enterotoxigenic F4+ Escherichia coli on intestinal cells","volume":"16","author":"Roselli","year":"2016","journal-title":"BMC Microbiol"},{"key":"10.1016\/j.tjnut.2023.12.004_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.846991","article-title":"Tibetan pig-derived probiotic Lactobacillus amylovorus SLZX20-1 improved intestinal function via producing enzymes and regulating intestinal microflora","volume":"9","author":"Shen","year":"2022","journal-title":"Front. Nutr."},{"key":"10.1016\/j.tjnut.2023.12.004_bib10","article-title":"Strain specificity of lactobacilli with promoted colonization by galactooligosaccharides administration in protecting intestinal barriers during Salmonella infection","author":"Wu","year":"2023","journal-title":"J. Adv. Res."},{"issue":"6","key":"10.1016\/j.tjnut.2023.12.004_bib11","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1016\/j.tjnut.2023.04.016","article-title":"Proinflammatory polarization of macrophages causes intestinal inflammation in low-birth-weight piglets and mice","volume":"153","author":"Zhang","year":"2023","journal-title":"J.\u00a0Nutr."},{"key":"10.1016\/j.tjnut.2023.12.004_bib12","doi-asserted-by":"crossref","first-page":"20506","DOI":"10.1021\/acsomega.0c02667","article-title":"Short administration of combined prebiotics improved microbial colonization, gut barrier, and growth performance of neonatal piglets","volume":"5","author":"Wu","year":"2020","journal-title":"ACS Omega"},{"issue":"10","key":"10.1016\/j.tjnut.2023.12.004_bib13","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1017\/S1751731116000690","article-title":"Nutrient-intake-level-dependent regulation of intestinal development in newborn intrauterine growth-restricted piglets via glucagon-like peptide-2","volume":"10","author":"Liu","year":"2016","journal-title":"Animal"},{"issue":"2","key":"10.1016\/j.tjnut.2023.12.004_bib14","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.aninu.2020.07.012","article-title":"Early life administration of milk fat globule membrane promoted SCFA-producing bacteria colonization, intestinal barriers and growth performance of neonatal piglets","volume":"7","author":"Wu","year":"2021","journal-title":"Anim. Nutr."},{"key":"10.1016\/j.tjnut.2023.12.004_bib15","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/s40104-018-0291-8","article-title":"Recent progress of porcine milk components and mammary gland function","volume":"9","author":"Zhang","year":"2018","journal-title":"J.\u00a0Anim. Sci. Biotechnol."},{"issue":"7","key":"10.1016\/j.tjnut.2023.12.004_bib16","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.3390\/ani10071218","article-title":"Evaluation of oral administration of Lactobacillus plantarum CAM6 strain as an alternative to antibiotics in weaned pigs","volume":"10","author":"Betancur","year":"2020","journal-title":"Animals (Basel)"},{"issue":"6","key":"10.1016\/j.tjnut.2023.12.004_bib17","first-page":"766","article-title":"Effects of probiotics on growth performance, blood parameters, and antibody stimulation in piglets","volume":"47","author":"Dlamini","year":"2017","journal-title":"S.\u00a0Afr. J. Anim. Sci."},{"issue":"5","key":"10.1016\/j.tjnut.2023.12.004_bib18","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1007\/s11427-022-2229-1","article-title":"Spraying compound probiotics improves growth performance and immunity and modulates gut microbiota and blood metabolites of suckling piglets","volume":"66","author":"Huang","year":"2022","journal-title":"Sci. China Life Sc."},{"issue":"3","key":"10.1016\/j.tjnut.2023.12.004_bib19","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1301\/nr.2003.marr.91-99","article-title":"Probiotics: considerations for human health","volume":"61","author":"Sanders","year":"2003","journal-title":"Nutr. Rev."},{"issue":"1","key":"10.1016\/j.tjnut.2023.12.004_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/19490976.2020.1830699","article-title":"Exposure to soil environments during earlier life stages is distinguishable in the gut microbiome of adult mice","volume":"13","author":"Liu","year":"2021","journal-title":"Gut. Microbes."},{"key":"10.1016\/j.tjnut.2023.12.004_bib21","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s12866-015-0372-1","article-title":"Lactobacillus reuteri I5007 modulates tight junction protein expression in IPEC-J2 cells with LPS stimulation and in newborn piglets under normal conditions","volume":"15","author":"Yang","year":"2015","journal-title":"BMC Microbiol"},{"key":"10.1016\/j.tjnut.2023.12.004_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.609722","article-title":"Probiotic gastrointestinal transit and colonization after oral administration: a long journey","volume":"11","author":"Han","year":"2021","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.tjnut.2023.12.004_bib23","doi-asserted-by":"crossref","first-page":"7260","DOI":"10.1039\/D1FO00084E","article-title":"Maternal galactooligosaccharides supplementation programmed immune defense, microbial colonization and intestinal development in piglets","volume":"12","author":"Wu","year":"2021","journal-title":"Food Funct"},{"issue":"1","key":"10.1016\/j.tjnut.2023.12.004_bib24","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1007\/s12602-018-9511-y","article-title":"Probiotic Lactobacillus johnsonii BS15 promotes growth performance, intestinal immunity, and gut microbiota in piglets","volume":"12","author":"Xin","year":"2020","journal-title":"Probiotics Antimicrob. Proteins."},{"issue":"10","key":"10.1016\/j.tjnut.2023.12.004_bib25","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1007\/s00125-018-4656-5","article-title":"Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2","volume":"61","author":"Ghezzi","year":"2018","journal-title":"Diabetologia"},{"issue":"5","key":"10.1016\/j.tjnut.2023.12.004_bib26","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1093\/biolre\/ioaa005","article-title":"Maternal curcumin supplementation ameliorates placental function and fetal growth in mice with intrauterine growth retardation","volume":"102","author":"Qi","year":"2020","journal-title":"Biol. Reprod."}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623727910?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623727910?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T05:46:10Z","timestamp":1758347170000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316623727910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["S0022316623727910"],"URL":"https:\/\/doi.org\/10.1016\/j.tjnut.2023.12.004","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lactobacillus amylovorus Promotes Lactose Utilization in Small Intestine and Enhances Intestinal Barrier Function in Intrauterine Growth Restricted Piglets","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjnut.2023.12.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American Society for Nutrition. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}