{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:12:42Z","timestamp":1786997562102,"version":"build-2736575974"},"reference-count":39,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004731","name":"Zhejiang Province Natural Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.tjnut.2024.07.012","type":"journal-article","created":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T05:34:13Z","timestamp":1721108053000},"page":"2909-2919","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["A Comprehensive Investigation of Dietary Micronutrient Intakes and Risk of Alcoholic Liver Disease"],"prefix":"10.1016","volume":"154","author":[{"given":"Jiayu","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yudan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohui","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingying","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songtao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.tjnut.2024.07.012_bib1","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/hep.30866","article-title":"Diagnosis and treatment of alcohol-associated liver diseases: 2019 practice guidance from the American Association for the Study of Liver Diseases","volume":"71","author":"Crabb","year":"2020","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.tjnut.2024.07.012_bib2","first-page":"307","article-title":"Practice Guideline Committee of the American Association for the Study of Liver Diseases, Practice Parameters Committee of the American College of Gastroenterology, Alcoholic liver disease","volume":"51","author":"O\u2019Shea","year":"2010","journal-title":"Hepatology"},{"issue":"2","key":"10.1016\/j.tjnut.2024.07.012_bib3","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.jhep.2021.10.005","article-title":"A\u00a0genetic risk score and diabetes predict development of alcohol-related cirrhosis in drinkers","volume":"76","author":"Whitfield","year":"2022","journal-title":"J.\u00a0Hepatol."},{"issue":"3","key":"10.1016\/j.tjnut.2024.07.012_bib4","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1093\/alcalc\/agab060","article-title":"The role of micronutrients in the pathogenesis of alcohol-related liver disease","volume":"57","author":"Nicoll","year":"2022","journal-title":"Alcohol Alcohol"},{"issue":"31","key":"10.1016\/j.tjnut.2024.07.012_bib5","doi-asserted-by":"crossref","first-page":"4567","DOI":"10.3748\/wjg.v26.i31.4567","article-title":"Current understanding of the metabolism of micronutrients in chronic alcoholic liver disease","volume":"26","author":"Wu","year":"2020","journal-title":"World J. Gastroenterol."},{"issue":"8","key":"10.1016\/j.tjnut.2024.07.012_bib6","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1053\/j.gastro.2016.01.037","article-title":"Genetic factors that affect risk of alcoholic and nonalcoholic fatty liver disease","volume":"150","author":"Anstee","year":"2016","journal-title":"Gastroenterology"},{"issue":"12","key":"10.1016\/j.tjnut.2024.07.012_bib7","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1038\/ng.3417","article-title":"A\u00a0genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis","volume":"47","author":"Buch","year":"2015","journal-title":"Nat. Genet."},{"issue":"5","key":"10.1016\/j.tjnut.2024.07.012_bib8","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1002\/hep.31535","article-title":"Genome-wide association study and meta-analysis on alcohol-associated liver cirrhosis identifies genetic risk factors","volume":"73","author":"Schwantes-An","year":"2021","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.tjnut.2024.07.012_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.diabet.2023.101499","article-title":"A\u00a0healthful plant-based diet is associated with lower type 2 diabetes risk via improved metabolic state and organ function: a prospective cohort study","volume":"50","author":"Thompson","year":"2024","journal-title":"Diabetes Metab"},{"issue":"5","key":"10.1016\/j.tjnut.2024.07.012_bib10","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.1007\/s00394-021-02535-x","article-title":"Describing a new food group classification system for UK Biobank: analysis of food groups and sources of macro- and micronutrients in 208,200 participants","volume":"60","author":"Piernas","year":"2021","journal-title":"Eur. J. Nutr."},{"issue":"7","key":"10.1016\/j.tjnut.2024.07.012_bib11","doi-asserted-by":"crossref","first-page":"4019","DOI":"10.1007\/s00394-021-02558-4","article-title":"Description of the updated nutrition calculation of the Oxford WebQ questionnaire and comparison with the previous version among 207,144 participants in UK Biobank","volume":"60","author":"Perez-Cornago","year":"2021","journal-title":"Eur. J. Nutr."},{"issue":"1","key":"10.1016\/j.tjnut.2024.07.012_bib12","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/oxfordjournals.aje.a114366","article-title":"Total energy intake: implications for epidemiologic analyses","volume":"124","author":"Willett","year":"1986","journal-title":"Am. J. Epidemiol."},{"issue":"1","key":"10.1016\/j.tjnut.2024.07.012_bib13","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/s41572-018-0014-7","article-title":"Alcoholic liver disease","volume":"4","author":"Seitz","year":"2018","journal-title":"Nat. Rev. Dis. Primers."},{"issue":"24","key":"10.1016\/j.tjnut.2024.07.012_bib14","doi-asserted-by":"crossref","first-page":"5335","DOI":"10.3390\/nu14245335","article-title":"Diet and risk of non-alcoholic fatty liver disease, cirrhosis, and liver cancer: a large prospective cohort study in UK Biobank","volume":"14","author":"Guo","year":"2022","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.tjnut.2024.07.012_bib15","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1186\/s12916-022-02622-8","article-title":"Alcohol consumption and hepatocellular carcinoma: novel insights from a prospective cohort study and nonlinear Mendelian randomization analysis","volume":"20","author":"Liu","year":"2022","journal-title":"BMC Med"},{"key":"10.1016\/j.tjnut.2024.07.012_bib16","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.envint.2018.12.037","article-title":"Associations of multiple plasma metals with the risk of ischemic stroke: a case-control study","volume":"125","author":"Wen","year":"2019","journal-title":"Environ. Int."},{"issue":"19","key":"10.1016\/j.tjnut.2024.07.012_bib17","doi-asserted-by":"crossref","first-page":"8785","DOI":"10.1039\/D3FO02069J","article-title":"Ultra-processed food consumption, mediating biomarkers, and risk of chronic obstructive pulmonary disease: a prospective cohort study in the UK Biobank","volume":"14","author":"He","year":"2023","journal-title":"Food Funct"},{"issue":"3","key":"10.1016\/j.tjnut.2024.07.012_bib18","first-page":"220","article-title":"Relationships between nutrition, alcohol use, and liver disease, Alcohol Res","volume":"27","author":"Lieber","year":"2003","journal-title":"Health"},{"issue":"3","key":"10.1016\/j.tjnut.2024.07.012_bib19","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.jhep.2010.03.029","article-title":"Impaired homocysteine transsulfuration is an indicator of alcoholic liver disease","volume":"53","author":"Medici","year":"2010","journal-title":"J.\u00a0Hepatol."},{"key":"10.1016\/j.tjnut.2024.07.012_bib20","doi-asserted-by":"crossref","DOI":"10.12659\/MSM.924602","article-title":"Differential metabolic pathways and metabolites in a C57BL\/6J mouse model of alcoholic liver disease","volume":"26","author":"Ma","year":"2020","journal-title":"Med. Sci. Monit."},{"issue":"4","key":"10.1016\/j.tjnut.2024.07.012_bib21","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1530-0277.1987.tb01329.x","article-title":"Pyridoxine deficiency and ethanol-induced liver injury","volume":"11","author":"Diehl","year":"1987","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"3","key":"10.1016\/j.tjnut.2024.07.012_bib22","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1158\/1055-9965.EPI-12-1169","article-title":"Alcohol consumption, folate intake, hepatocellular carcinoma, and liver disease mortality, Cancer Epidemiol","volume":"22","author":"Persson","year":"2013","journal-title":"Biomarkers Prev."},{"issue":"1","key":"10.1016\/j.tjnut.2024.07.012_bib23","doi-asserted-by":"crossref","first-page":"G54","DOI":"10.1152\/ajpgi.00542.2004","article-title":"Chronic ethanol feeding and folate deficiency activate hepatic endoplasmic reticulum stress pathway in micropigs","volume":"289","author":"Esfandiari","year":"2005","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"1\u20132","key":"10.1016\/j.tjnut.2024.07.012_bib24","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.cccn.2004.12.012","article-title":"Oxidative stress and antioxidant status in patients with alcoholic liver disease","volume":"355","author":"Masalkar","year":"2005","journal-title":"Clin. Chim. Acta."},{"issue":"1","key":"10.1016\/j.tjnut.2024.07.012_bib25","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S0168-8278(03)00476-8","article-title":"A\u00a0randomized placebo controlled trial of vitamin E for alcoholic hepatitis","volume":"40","author":"Mezey","year":"2004","journal-title":"J.\u00a0Hepatol."},{"issue":"2","key":"10.1016\/j.tjnut.2024.07.012_bib26","doi-asserted-by":"crossref","first-page":"82","DOI":"10.3109\/15376510903559950","article-title":"Influence of vitamin E on alcohol-induced changes in antioxidant defenses in mice liver","volume":"20","author":"Kaur","year":"2010","journal-title":"Toxicol. Mech. Methods."},{"issue":"2","key":"10.1016\/j.tjnut.2024.07.012_bib27","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1093\/alcalc\/agaa001","article-title":"Lower serum magnesium concentrations are associated with specific heavy drinking markers, pro-inflammatory response and early-stage alcohol-associated liver injury","volume":"55","author":"Vatsalya","year":"2020","journal-title":"Alcohol Alcohol"},{"issue":"3","key":"10.1016\/j.tjnut.2024.07.012_bib28","first-page":"523","article-title":"Serum concentration of zinc, copper, manganese and magnesium in patients with liver cirrhosis","volume":"30","author":"Raheli\u0107","year":"2006","journal-title":"Coll. Antropol."},{"issue":"1","key":"10.1016\/j.tjnut.2024.07.012_bib29","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-18076-5","article-title":"Magnesium intake and mortality due to liver diseases: results from the Third National Health and Nutrition Examination Survey Cohort","volume":"7","author":"Wu","year":"2017","journal-title":"Sci. Rep."},{"issue":"11","key":"10.1016\/j.tjnut.2024.07.012_bib30","doi-asserted-by":"crossref","first-page":"2088","DOI":"10.1017\/S1368980018000642","article-title":"Intakes of magnesium, calcium and risk of fatty liver disease and prediabetes","volume":"21","author":"Li","year":"2018","journal-title":"Public Health Nutr"},{"issue":"11","key":"10.1016\/j.tjnut.2024.07.012_bib31","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1177\/0960327111401049","article-title":"Influence of selenium and\/or magnesium on alleviation alcohol induced oxidative stress in rats, normalization function of liver and changes in serum lipid parameters","volume":"30","author":"Markiewicz-G\u00f3rka","year":"2011","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.tjnut.2024.07.012_bib32","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2017-220921","article-title":"Copper deficiency caused by excessive alcohol consumption","volume":"2017","author":"Shibazaki","year":"2017","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.tjnut.2024.07.012_bib33","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3389\/fphys.2020.00369","article-title":"Dietary copper plays an important role in maintaining intestinal barrier integrity during alcohol-induced liver disease through regulation of the intestinal HIF-1\u03b1 signaling pathway and oxidative stress","volume":"11","author":"Lin","year":"2020","journal-title":"Front. Physiol."},{"issue":"1","key":"10.1016\/j.tjnut.2024.07.012_bib34","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/ajg.2009.593","article-title":"Alcoholic liver disease","volume":"105","author":"O'Shea","year":"2010","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.tjnut.2024.07.012_bib35","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.nut.2019.05.004","article-title":"Creatine supplementation exacerbates ethanol-induced hepatic damage in mice","volume":"66","author":"Marinello","year":"2019","journal-title":"Nutrition"},{"issue":"4","key":"10.1016\/j.tjnut.2024.07.012_bib36","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1111\/j.1572-0241.1999.01006.x","article-title":"The ratio of aspartate aminotransferase to alanine aminotransferase: potential value in differentiating nonalcoholic steatohepatitis from alcoholic liver disease","volume":"94","author":"Sorbi","year":"1999","journal-title":"Am. J. Gastroenterol."},{"issue":"4","key":"10.1016\/j.tjnut.2024.07.012_bib37","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1093\/alcalc\/agh074","article-title":"High AST\/ALT ratio may indicate advanced alcoholic liver disease rather than heavy drinking","volume":"39","author":"Nyblom","year":"2004","journal-title":"Alcohol Alcohol"},{"issue":"3","key":"10.1016\/j.tjnut.2024.07.012_bib38","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/alcalc\/agl004","article-title":"Serum osteoprotegerin and RANKL levels in chronic alcoholic liver disease","volume":"41","author":"Garc\u00eda-Valdecasas-Campelo","year":"2006","journal-title":"Alcohol Alcohol"},{"issue":"4","key":"10.1016\/j.tjnut.2024.07.012_bib39","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1093\/oxfordjournals.alcalc.a044918","article-title":"The interactions of insulin-like growth factor I(IGF-I) with protein-calorie malnutrition in patients with alcoholic liver disease: V.A. Cooperative Study on Alcoholic Hepatitis VI","volume":"24","author":"Mendenhall","year":"1989","journal-title":"Alcohol Alcohol"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316624003936?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316624003936?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:16:09Z","timestamp":1759331769000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316624003936"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":39,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["S0022316624003936"],"URL":"https:\/\/doi.org\/10.1016\/j.tjnut.2024.07.012","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Comprehensive Investigation of Dietary Micronutrient Intakes and Risk of Alcoholic Liver Disease","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjnut.2024.07.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 American Society for Nutrition. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}