{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T09:46:51Z","timestamp":1789984011408,"version":"4.0.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017618","name":"National Institute of Diabetes and Digestive and Kidney Diseases Division of Diabetes Endocrinology and Metabolic Diseases","doi-asserted-by":"publisher","award":["R01 DK107390 01"],"award-info":[{"award-number":["R01 DK107390 01"]}],"id":[{"id":"10.13039\/100017618","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.tjnut.2024.10.007","type":"journal-article","created":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T02:00:26Z","timestamp":1728525626000},"page":"3585-3591","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Preliminary Evidence Supports that Long-Term Consumption of Higher-Protein Breakfast Promotes Higher Expression of Select miRNA Associated with Cardiometabolic Health in Adolescents"],"prefix":"10.1016","volume":"154","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-8261-2392","authenticated-orcid":false,"given":"Kamille A","family":"Piacquadio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee M","family":"Margolis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jess A","family":"Gwin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather J","family":"Leidy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tjnut.2024.10.007_bib1","year":"2021","journal-title":"Obesity and overweight [Internet]"},{"issue":"2","key":"10.1016\/j.tjnut.2024.10.007_bib2","doi-asserted-by":"crossref","first-page":"387","DOI":"10.3390\/nu11020387","article-title":"A\u00a0systematic review of the association of skipping breakfast with weight and cardiometabolic risk factors in children and adolescents. What should we better investigate in the future?","volume":"11","author":"Monzani","year":"2019","journal-title":"Nutrients"},{"issue":"7","key":"10.1016\/j.tjnut.2024.10.007_bib3","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1017\/S1368980012000973","article-title":"Breakfast consumption and CVD risk factors in European adolescents: the HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) study","volume":"16","author":"Hallstr\u00f6m","year":"2013","journal-title":"Public Health Nutr"},{"key":"10.1016\/j.tjnut.2024.10.007_bib4","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2023.1222536","article-title":"The effect of breakfast on childhood obesity: a systematic review and meta-analysis","volume":"10","author":"Wang","year":"2023","journal-title":"Front Nutr"},{"issue":"3","key":"10.1016\/j.tjnut.2024.10.007_bib5","doi-asserted-by":"crossref","first-page":"613S","DOI":"10.3945\/an.115.010314","article-title":"The effects of breakfast consumption and composition on metabolic wellness with a focus on carbohydrate metabolism","volume":"7","author":"Maki","year":"2016","journal-title":"Adv. Nutr."},{"issue":"9","key":"10.1016\/j.tjnut.2024.10.007_bib6","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1002\/oby.21185","article-title":"A\u00a0high-protein breakfast prevents body fat gain, through reductions in daily intake and hunger, in \u201cBreakfast skipping\u201d adolescents","volume":"23","author":"Leidy","year":"2015","journal-title":"Obesity (Silver Spring)"},{"issue":"9","key":"10.1016\/j.tjnut.2024.10.007_bib7","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1038\/ijo.2015.101","article-title":"A\u00a0pilot study examining the effects of consuming a high-protein vs normal-protein breakfast on free-living glycemic control in overweight\/obese \u2018breakfast skipping\u2019 adolescents","volume":"39","author":"Bauer","year":"2015","journal-title":"Int. J. Obes. (Lond)."},{"issue":"4","key":"10.1016\/j.tjnut.2024.10.007_bib8","doi-asserted-by":"crossref","first-page":"677","DOI":"10.3945\/ajcn.112.053116","article-title":"Beneficial effects of a higher-protein breakfast on the appetitive, hormonal, and neural signals controlling energy intake regulation in overweight\/obese, \u201cbreakfast-skipping,\u201d late-adolescent girls","volume":"97","author":"Leidy","year":"2013","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.tjnut.2024.10.007_bib9","doi-asserted-by":"crossref","first-page":"402","DOI":"10.3389\/fendo.2018.00402","article-title":"Overview of microRNA biogenesis, mechanisms of actions, and circulation","volume":"9","author":"O\u2019Brien","year":"2018","journal-title":"Front Endocrinol. (Lausanne)."},{"issue":"2","key":"10.1016\/j.tjnut.2024.10.007_bib10","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1097\/MOL.0b013e328350a425","article-title":"Lipid-based carriers of microRNAs and intercellular communication","volume":"23","author":"Vickers","year":"2012","journal-title":"Curr. Opin. Lipidol."},{"issue":"7","key":"10.1016\/j.tjnut.2024.10.007_bib11","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1111\/apm.12389","article-title":"Profiling peripheral microRNAs in obesity and type 2 diabetes mellitus","volume":"123","author":"Wu","year":"2015","journal-title":"APMIS"},{"issue":"12","key":"10.1016\/j.tjnut.2024.10.007_bib12","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.3390\/cells8121533","article-title":"MicroRNA signatures as future biomarkers for diagnosis of diabetes states","volume":"8","author":"Vasu","year":"2019","journal-title":"Cells"},{"issue":"7","key":"10.1016\/j.tjnut.2024.10.007_bib13","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1038\/aps.2018.30","article-title":"miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges","volume":"39","author":"Zhou","year":"2018","journal-title":"Acta Pharmacol. Sin."},{"issue":"6","key":"10.1016\/j.tjnut.2024.10.007_bib14","doi-asserted-by":"crossref","first-page":"770","DOI":"10.3390\/nu16060770","article-title":"The impact of diet on miRNA regulation and its implications for health: a systematic review","volume":"16","author":"DeLucas","year":"2024","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.tjnut.2024.10.007_bib15","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s12263-020-0660-8","article-title":"Inflexibility of the plasma miRNA response following a high-carbohydrate meal in overweight insulin-resistant women","volume":"15","author":"Ramzan","year":"2020","journal-title":"Genes Nutr"},{"issue":"3","key":"10.1016\/j.tjnut.2024.10.007_bib16","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1093\/ajcn\/81.3.564","article-title":"Genetic and environmental influences on eating behavior: the Swedish Young Male Twins Study","volume":"81","author":"Tholin","year":"2005","journal-title":"Am. J. Clin. Nutr."},{"issue":"4","key":"10.1016\/j.tjnut.2024.10.007_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0153200","article-title":"Comparison of methodologies to detect low levels of hemolysis in serum for accurate assessment of serum microRNAs","volume":"11","author":"Shah","year":"2016","journal-title":"PLOS ONE"},{"issue":"9","key":"10.1016\/j.tjnut.2024.10.007_bib18","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","article-title":"A\u00a0new mathematical model for relative quantification in real-time RT-PCR","volume":"29","author":"Pfaffl","year":"2001","journal-title":"Nucleic Acids Res"},{"issue":"6","key":"10.1016\/j.tjnut.2024.10.007_bib19","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1016\/j.tjnut.2024.04.026","article-title":"Higher expression of miR-15b-5p with inclusion of fresh, lean beef as part of a healthy dietary pattern is inversely associated with markers of cardio-metabolic disease risk","volume":"154","author":"Piacquadio","year":"2024","journal-title":"J.\u00a0Nutr."},{"issue":"6","key":"10.1016\/j.tjnut.2024.10.007_bib20","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1002\/oby.22791","article-title":"Breakfast skipping, body composition, and cardiometabolic risk: a systematic review and meta-analysis of randomized trials","volume":"28","author":"Bonnet","year":"2020","journal-title":"Obesity (Silver Spring)"},{"issue":"2","key":"10.1016\/j.tjnut.2024.10.007_bib21","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.devcel.2008.07.002","article-title":"The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis","volume":"15","author":"Wang","year":"2008","journal-title":"Dev. Cell."},{"issue":"6","key":"10.1016\/j.tjnut.2024.10.007_bib22","doi-asserted-by":"crossref","first-page":"10567","DOI":"10.3390\/ijms150610567","article-title":"The role of circulating microRNA-126 (miR-126): a novel biomarker for screening prediabetes and newly diagnosed type 2 diabetes mellitus","volume":"15","author":"Liu","year":"2014","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.tjnut.2024.10.007_bib23","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1002\/oby.22704","article-title":"Levels of circulating miR-122 are associated with weight loss and metabolic syndrome","volume":"28","author":"Hess","year":"2020","journal-title":"Obesity (Silver Spring)"},{"issue":"5","key":"10.1016\/j.tjnut.2024.10.007_bib24","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.beem.2016.11.010","article-title":"MicroRNAs in lipid metabolism and atherosclerosis","volume":"30","author":"Giral","year":"2016","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.tjnut.2024.10.007_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102531","article-title":"Association between lipid peroxidation biomarkers and microRNA expression profiles","volume":"58","author":"Zhao","year":"2022","journal-title":"Redox Biol"},{"issue":"7893","key":"10.1016\/j.tjnut.2024.10.007_bib26","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/s41586-021-04234-3","article-title":"MicroRNA sequence codes for small extracellular vesicle release and cellular retention","volume":"601","author":"Garcia-Martin","year":"2022","journal-title":"Nature"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316624010745?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316624010745?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T01:06:06Z","timestamp":1764551166000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316624010745"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":26,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S0022316624010745"],"URL":"https:\/\/doi.org\/10.1016\/j.tjnut.2024.10.007","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preliminary Evidence Supports that Long-Term Consumption of Higher-Protein Breakfast Promotes Higher Expression of Select miRNA Associated with Cardiometabolic Health in Adolescents","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjnut.2024.10.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 American Society for Nutrition. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}