{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T20:24:43Z","timestamp":1783110283821,"version":"3.54.6"},"reference-count":67,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002842","name":"Chiang Mai University","doi-asserted-by":"publisher","award":["138\/2567"],"award-info":[{"award-number":["138\/2567"]}],"id":[{"id":"10.13039\/501100002842","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010731","name":"Faculty of Medicine, Chiang Mai University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.tjnut.2026.101574","type":"journal-article","created":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T22:50:43Z","timestamp":1777762243000},"page":"101574","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of a Mixed Herbal and Fruit Dietary Supplement Shot on Antioxidant Status, Oxidative Stress Parameters, Skin Parameters, and Safety Profiles in Middle-Aged Women: A Randomized, Double-Blind, Placebo-Controlled Trial"],"prefix":"10.1016","volume":"156","author":[{"given":"Kornvipa","family":"Settakorn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pannita","family":"Anek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingkwan","family":"Na Takuathung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pattarachon","family":"Apisitwittaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakkrit","family":"Aisara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kantirat","family":"Yaja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeeraporn","family":"Chitphan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ratchanon","family":"Inpan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preeyaporn","family":"Klinjan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tattiya","family":"Kantasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nahathai","family":"Dukaew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kankanit","family":"Yeerong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wichaya","family":"Karat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4649-597X","authenticated-orcid":false,"given":"Nut","family":"Koonrungsesomboon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tjnut.2026.101574_bib1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.bbi.2022.05.016","article-title":"Stress-induced biological aging: a review and guide for research priorities","volume":"104","author":"Polsky","year":"2022","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.tjnut.2026.101574_bib2","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.mayocp.2020.07.033","article-title":"Hormonal and metabolic changes of aging and the influence of lifestyle modifications","volume":"96","author":"Pataky","year":"2021","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.tjnut.2026.101574_bib3","doi-asserted-by":"crossref","first-page":"4972","DOI":"10.18103\/mra.v12i1.4972","article-title":"Hormonal-metabolic trajectory of menopausal transition in a normoglycemic cohort of women with different blood pressure levels","volume":"12","author":"Ruyatkina","year":"2024","journal-title":"Med. Res. Arch."},{"key":"10.1016\/j.tjnut.2026.101574_bib4","article-title":"Women\u2019s health, hormonal balance, and personal autonomy","volume":"10","author":"Segarra","year":"2023","journal-title":"Front. Med. (Lausanne)."},{"key":"10.1016\/j.tjnut.2026.101574_bib5","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1080\/15427609.2015.1068048","article-title":"Mind the gap in the middle: a call to study midlife","volume":"12","author":"Lachman","year":"2015","journal-title":"Res. Hum. Dev."},{"key":"10.1016\/j.tjnut.2026.101574_bib6","series-title":"Oxidative Stress and Chronic Degenerative Diseases\u2014A Role for Antioxidants","first-page":"331","article-title":"Aging, oxidative stress and antioxidants","author":"Milisav","year":"2013"},{"key":"10.1016\/j.tjnut.2026.101574_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2022.827900","article-title":"A comprehensive overview of the complex role of oxidative stress in aging, the contributing environmental stressors and emerging antioxidant therapeutic interventions","volume":"14","author":"Iakovou","year":"2022","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.tjnut.2026.101574_bib8","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1111\/ics.12728","article-title":"Oxidative stress in the skin: impact and related protection","volume":"43","author":"Chen","year":"2021","journal-title":"Int. J. Cosmet. Sci."},{"key":"10.1016\/j.tjnut.2026.101574_bib9","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s40142-022-00205-w","article-title":"Genetic, social, and lifestyle drivers of healthy aging and longevity","volume":"10","author":"Castruita","year":"2022","journal-title":"Curr. Genet. Med. Rep."},{"key":"10.1016\/j.tjnut.2026.101574_bib10","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.3390\/antiox11061121","article-title":"Focus on the contribution of oxidative stress in skin aging","volume":"11","author":"Papaccio","year":"2022","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.tjnut.2026.101574_bib11","doi-asserted-by":"crossref","first-page":"545","DOI":"10.3390\/biom5020545","article-title":"Oxidative stress in aging human skin","volume":"5","author":"Rinnerthaler","year":"2015","journal-title":"Biomolecules"},{"key":"10.1016\/j.tjnut.2026.101574_bib12","doi-asserted-by":"crossref","first-page":"22","DOI":"10.2174\/1567205016666190809161115","article-title":"Skin ageing: pathophysiology and current market treatment approaches","volume":"13","author":"Chaudhary","year":"2020","journal-title":"Curr. Aging Sci."},{"key":"10.1016\/j.tjnut.2026.101574_bib13","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-01573-z","article-title":"Defining skin aging and its risk factors: a systematic review and meta-analysis","volume":"11","author":"Wong","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tjnut.2026.101574_bib14","doi-asserted-by":"crossref","DOI":"10.1111\/jocd.16688","article-title":"Influences on skin and intrinsic aging: biological, environmental, and therapeutic insights","volume":"24","author":"Hussein","year":"2025","journal-title":"J. Cosmet. Dermatol."},{"key":"10.1016\/j.tjnut.2026.101574_bib15","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.clindermatol.2021.11.001","article-title":"Reproduction, skin aging, and sleep in middle-aged women","volume":"40","author":"Xerfan","year":"2022","journal-title":"Clin. Dermatol."},{"key":"10.1016\/j.tjnut.2026.101574_bib16","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1177\/0963689717725755","article-title":"Fighting against skin aging: the way from bench to bedside","volume":"27","author":"Zhang","year":"2018","journal-title":"Cell Transplant"},{"key":"10.1016\/j.tjnut.2026.101574_bib17","doi-asserted-by":"crossref","first-page":"174","DOI":"10.3390\/antiox13020174","article-title":"Ascorbic acid treatments as effective and safe anti-aging therapies for sensitive skin","volume":"13","author":"Jaros-Sajda","year":"2024","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.tjnut.2026.101574_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2021.102388","article-title":"Quantitative assessment of age-dependent changes in porphyrins from fluorescence images of ultraviolet photography by image processing","volume":"35","author":"Wu","year":"2021","journal-title":"Photodiagnosis Photodyn. Ther."},{"key":"10.1016\/j.tjnut.2026.101574_bib19","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s40101-025-00408-4","article-title":"Dietary interventions in skin ageing: a systematic review and meta-analysis","volume":"44","author":"Ng","year":"2025","journal-title":"J. Physiol. Anthropol."},{"key":"10.1016\/j.tjnut.2026.101574_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.806470","article-title":"Dietary polyphenols and their role in oxidative stress-induced human diseases: insights into protective effects, antioxidant potentials and mechanism(s) of action","volume":"13","author":"Rudrapal","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.tjnut.2026.101574_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2025.111489","article-title":"Flavonoids and their role in oxidative stress, inflammation, and human diseases","volume":"413","author":"Jomova","year":"2025","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.tjnut.2026.101574_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101471","article-title":"Antioxidant supplements and endurance exercise: current evidence and mechanistic insights","volume":"35","author":"Mason","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.tjnut.2026.101574_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2020.e05382","article-title":"Characterization of phytochemicals, minerals and in vitro medicinal activities of bael (Aegle marmelos L.) pulp and differently dried edible leathers","volume":"6","author":"Hazra","year":"2020","journal-title":"Heliyon"},{"key":"10.1016\/j.tjnut.2026.101574_bib24","doi-asserted-by":"crossref","DOI":"10.3390\/ijms231810889","article-title":"Aegle marmelos (L.) Correa: an underutilized fruit with high nutraceutical values: a review","volume":"23","author":"Sharma","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tjnut.2026.101574_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.focha.2025.100935","article-title":"Aegle marmelos (L.): an underutilized plant with incredible pharmaceutical and nutritional potential","volume":"6","author":"Yadav","year":"2025","journal-title":"Food Chem. Adv"},{"key":"10.1016\/j.tjnut.2026.101574_bib26","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.fitote.2008.01.007","article-title":"Antioxidant activity of banana flavonoids","volume":"79","author":"Vijayakumar","year":"2008","journal-title":"Fitoterapia"},{"key":"10.1016\/j.tjnut.2026.101574_bib27","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1007\/s13197-015-2096-5","article-title":"Antihypercholesterolemic and antioxidant effect of sterol rich methanol extract of stem of Musa sapientum (banana) in cholesterol fed wistar rats","volume":"53","author":"Dikshit","year":"2016","journal-title":"J. Food Sci. Technol."},{"key":"10.1016\/j.tjnut.2026.101574_bib28","article-title":"Houttuynia Cordata Thunb.: a comprehensive review of traditional applications, phytochemistry","volume":"123","author":"Wei","year":"2024","journal-title":"pharmacology and safety, Phytomedicine"},{"key":"10.1016\/j.tjnut.2026.101574_bib29","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3390\/antiox11020221","article-title":"Hyperoside and quercitrin in Houttuynia cordata extract attenuate UVB-induced human keratinocyte cell damage and oxidative stress via modulation of MAPKs and Akt signaling pathway","volume":"11","author":"Charachit","year":"2022","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.tjnut.2026.101574_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2022.e10386","article-title":"The therapeutic potential of Houttuynia cordata: a current review","volume":"8","author":"Laldinsangi","year":"2022","journal-title":"Heliyon"},{"key":"10.1016\/j.tjnut.2026.101574_bib31","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1002\/jat.4198","article-title":"Acute and subacute toxicity evaluation of Houttuynia cordata ethanol extract and plasma metabolic profiling analysis in both male and female rats","volume":"41","author":"Chen","year":"2021","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.tjnut.2026.101574_bib32","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jep.2016.05.023","article-title":"Angelica sinensis in China-A review of botanical profile, ethnopharmacology, phytochemistry and chemical analysis","volume":"190","author":"Wei","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.tjnut.2026.101574_bib33","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1002\/ptr.1617","article-title":"Antioxidant activities of some common ingredients of traditional Chinese medicine, Angelica sinensis, Lycium barbarum and Poria cocos","volume":"18","author":"Wu","year":"2004","journal-title":"Phytother. Res."},{"key":"10.1016\/j.tjnut.2026.101574_bib34","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.3390\/ijms18112331","article-title":"Polyphenol-rich dry common beans (Phaseolus vulgaris L.) and their health benefits","volume":"18","author":"Ganesan","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tjnut.2026.101574_bib35","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s13765-013-3048-2","article-title":"Changes in phenolic compounds (Isoflavones and Phenolic acids) and antioxidant properties in high-protein soybean (Glycine max L., cv. Saedanbaek) for different roasting conditions","volume":"56","author":"Lee","year":"2013","journal-title":"J. Korean Soc. Appl. Biol. Chem."},{"key":"10.1016\/j.tjnut.2026.101574_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2020.109578","article-title":"Effect of soy products and isoflavones on oxidative stress parameters: a systematic review and meta-analysis of randomized controlled trials","volume":"137","author":"Morvaridzadeh","year":"2020","journal-title":"Food Res. Int."},{"key":"10.1016\/j.tjnut.2026.101574_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2024.106055","article-title":"The effects of SOY extract nutraceuticals on postmenopausal women\u2019s health: a randomized, double-blind, placebo-controlled trial","volume":"113","author":"Na Takuathung","year":"2024","journal-title":"J. Funct. Foods."},{"key":"10.1016\/j.tjnut.2026.101574_bib38","doi-asserted-by":"crossref","first-page":"4001","DOI":"10.3390\/ijms26094001","article-title":"Skin photoprotection and anti-aging benefits of a combination of rosemary and grapefruit extracts: evidence from in vitro models and human study","volume":"26","author":"Navarro","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tjnut.2026.101574_bib39","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/8915729","article-title":"Bioactive flavonoids, antioxidant behaviour, and cytoprotective effects of dried grapefruit peels (Citrus paradisi Macf.)","volume":"2016","author":"Castro-Vazquez","year":"2016","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.tjnut.2026.101574_bib40","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1179\/135100004225004742","article-title":"Antioxidant efficacy of black pepper (Piper nigrum L.) and piperine in rats with high fat diet induced oxidative stress","volume":"9","author":"Vijayakumar","year":"2004","journal-title":"Redox Rep"},{"key":"10.1016\/j.tjnut.2026.101574_bib41","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1159\/000441683","article-title":"The therapeutic potential of resistant starch in modulation of insulin resistance, endotoxemia, oxidative stress and antioxidant biomarkers in women with type 2 diabetes: a randomized controlled clinical trial","volume":"68","author":"Karimi","year":"2016","journal-title":"Ann. Nutr. Metab."},{"key":"10.1016\/j.tjnut.2026.101574_bib42","doi-asserted-by":"crossref","first-page":"4169","DOI":"10.3390\/molecules26144169","article-title":"Chemical analysis, toxicity study, and free-radical scavenging and iron-binding assays involving coffee (Coffea arabica) extracts","volume":"26","author":"Hutachok","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.tjnut.2026.101574_bib43","doi-asserted-by":"crossref","DOI":"10.1002\/fsn3.70329","article-title":"Phytochemical analysis and anti-lipid accumulation effects of Pulsed Electric Field (PEF)-Processed black rice and green tea extracts in oleic acid-induced hepatocytes","volume":"13","author":"Paradee","year":"2025","journal-title":"Food Sci. Nutr."},{"key":"10.1016\/j.tjnut.2026.101574_bib44","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1177\/1090820X13510170","article-title":"Development and psychometric evaluation of the FACE-Q Aging Appraisal Scale and Patient-Perceived Age Visual Analog Scale","volume":"33","author":"Panchapakesan","year":"2013","journal-title":"Aesthet. Surg. J."},{"key":"10.1016\/j.tjnut.2026.101574_bib45","first-page":"151","article-title":"Phytonutrients as therapeutic agents, J. Complement. Integr","volume":"11","author":"Gupta","year":"2014","journal-title":"Med."},{"key":"10.1016\/j.tjnut.2026.101574_bib46","first-page":"261","article-title":"Juices and beverages with a controlled phenolic content and antioxidant capacity","volume":"13","author":"Owczarek","year":"2004","journal-title":"Pol. J. Food Nutr. Sci."},{"key":"10.1016\/j.tjnut.2026.101574_bib47","doi-asserted-by":"crossref","first-page":"797","DOI":"10.3390\/antiox9090797","article-title":"Polyphenols by generating H(2)O(2), affect cell redox signaling, inhibit PTPs and activate Nrf2 axis for adaptation and cell surviving: in vitro, in vivo and human health","volume":"9","author":"Kanner","year":"2020","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.tjnut.2026.101574_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1240433","article-title":"Nrf2-mediated therapeutic effects of dietary flavones in different diseases","volume":"14","author":"Huang","year":"2023","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.tjnut.2026.101574_bib49","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1083\/jcb.201708007","article-title":"Superoxide dismutases: dual roles in controlling ROS damage and regulating ROS signaling","volume":"217","author":"Wang","year":"2018","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.tjnut.2026.101574_bib50","doi-asserted-by":"crossref","first-page":"6939","DOI":"10.1039\/D1TB00720C","article-title":"Superoxide dismutase nanozyme: an emerging star for anti-oxidation","volume":"9","author":"Zhao","year":"2021","journal-title":"J. Mater. Chem. B."},{"key":"10.1016\/j.tjnut.2026.101574_bib51","article-title":"Oxidative stress: signaling pathways, biological functions, and disease","volume":"6","author":"Liu","year":"2025","journal-title":"MedComm (2020)"},{"key":"10.1016\/j.tjnut.2026.101574_bib52","first-page":"373","article-title":"Superoxide dismutase and neurological disorders, IBRO Neurosci","volume":"16","author":"Chidambaram","year":"2024","journal-title":"Rep"},{"key":"10.1016\/j.tjnut.2026.101574_bib53","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.3390\/antiox11122345","article-title":"Nrf2 and oxidative stress: a general overview of mechanisms and implications in human disease","volume":"11","author":"Ngo","year":"2022","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.tjnut.2026.101574_bib54","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.3390\/biom15081130","article-title":"Therapeutic applications and mechanisms of superoxide dismutase (SOD) in different pathogenesis","volume":"15","author":"Anwar","year":"2025","journal-title":"Biomolecules"},{"key":"10.1016\/j.tjnut.2026.101574_bib55","doi-asserted-by":"crossref","first-page":"834","DOI":"10.3390\/antiox12040834","article-title":"Cellular compartmentalization, glutathione transport and its relevance in some pathologies","volume":"12","author":"V\u00e1zquez-Meza","year":"2023","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.tjnut.2026.101574_bib56","doi-asserted-by":"crossref","first-page":"280","DOI":"10.11002\/fsp.2025.32.2.280","article-title":"Antioxidant and anti-wrinkle effects of fermented Houttuynia cordata extract","volume":"32","author":"Park","year":"2025","journal-title":"Food Sci. Preserv."},{"key":"10.1016\/j.tjnut.2026.101574_bib57","doi-asserted-by":"crossref","first-page":"308","DOI":"10.4161\/derm.22804","article-title":"Skin anti-aging strategies","volume":"4","author":"Ganceviciene","year":"2012","journal-title":"Dermatoendocrinol"},{"key":"10.1016\/j.tjnut.2026.101574_bib58","doi-asserted-by":"crossref","first-page":"4839","DOI":"10.3390\/molecules28124839","article-title":"Skin pigmentation types, causes and treatment-a review","volume":"28","author":"Thawabteh","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.tjnut.2026.101574_bib59","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.2147\/CCID.S479411","article-title":"Tranexamic acid for the treatment of hyperpigmentation and telangiectatic disorders other than melasma: an update","volume":"17","author":"Chen","year":"2024","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"10.1016\/j.tjnut.2026.101574_bib60","doi-asserted-by":"crossref","DOI":"10.1128\/mSphere.00793-19","article-title":"Porphyrin production and regulation in cutaneous Propionibacteria","volume":"5","author":"Barnard","year":"2020","journal-title":"mSphere"},{"key":"10.1016\/j.tjnut.2026.101574_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2021.102575","article-title":"Porphyrins produced by acneic Cutibacterium acnes strains activate the inflammasome by inducing K(+) leakage","volume":"24","author":"Spittaels","year":"2021","journal-title":"iScience"},{"key":"10.1016\/j.tjnut.2026.101574_bib62","first-page":"1433","article-title":"Markers of oxidative stress in patients with acne: a literature review","volume":"13","author":"Popa","year":"2023","journal-title":"Life (Basel)"},{"key":"10.1016\/j.tjnut.2026.101574_bib63","doi-asserted-by":"crossref","first-page":"4024","DOI":"10.1038\/s41598-018-22132-z","article-title":"Inhibitory effects of superoxide dismutase 3 on Propionibacterium acnes-induced skin inflammation","volume":"8","author":"Nguyen","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tjnut.2026.101574_bib64","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.30574\/wjarr.2024.23.3.2738","article-title":"A comprehensive review of acne\u2019s facial impact and the therapeutic potential of Indian herbal medicine","volume":"23","author":"Tiwari","year":"2024","journal-title":"World J. Adv. Res. Rev."},{"key":"10.1016\/j.tjnut.2026.101574_bib65","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1111\/j.1749-6632.1998.tb10669.x","article-title":"Oral irritant effects of nicotine. Psychophysical evidence for decreased sensation following repeated application of and lack of cross-desensitization to capsaicin","volume":"855","author":"Dessirier","year":"1998","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.tjnut.2026.101574_bib66","doi-asserted-by":"crossref","first-page":"587","DOI":"10.13005\/bpj\/2641","article-title":"Effect of lifestyle factors on serum antioxidant concentrations in apparently healthy individuals","volume":"16","author":"Rangaraju","year":"2023","journal-title":"Biomed. Pharmacol. J."},{"key":"10.1016\/j.tjnut.2026.101574_bib67","doi-asserted-by":"crossref","DOI":"10.29219\/fnr.v65.5619","article-title":"Antioxidant and reduced skin-ageing effects of a polyphenol-enriched dietary supplement in response to air pollution: a randomized, double-blind, placebo-controlled study","volume":"65","author":"Nobile","year":"2021","journal-title":"Food Nutr. Res."}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316626002233?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316626002233?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T19:55:29Z","timestamp":1783108529000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316626002233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":67,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S0022316626002233"],"URL":"https:\/\/doi.org\/10.1016\/j.tjnut.2026.101574","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of a Mixed Herbal and Fruit Dietary Supplement Shot on Antioxidant Status, Oxidative Stress Parameters, Skin Parameters, and Safety Profiles in Middle-Aged Women: A Randomized, Double-Blind, Placebo-Controlled Trial","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjnut.2026.101574","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc. on behalf of American Society for Nutrition.","name":"copyright","label":"Copyright"}],"article-number":"101574"}}