{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T06:24:41Z","timestamp":1789885481755,"version":"4.0.1"},"reference-count":13,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,5,11]],"date-time":"2016-05-11T00:00:00Z","timestamp":1462924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","award":["MOST-103-2314-B-195-010"],"award-info":[{"award-number":["MOST-103-2314-B-195-010"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","award":["MOST-104-2314-B-195-009"],"award-info":[{"award-number":["MOST-104-2314-B-195-009"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004861","name":"MacKay Memorial Hospital","doi-asserted-by":"publisher","award":["MMH-E-105-04"],"award-info":[{"award-number":["MMH-E-105-04"]}],"id":[{"id":"10.13039\/501100004861","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Taiwanese Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.tjog.2016.05.002","type":"journal-article","created":{"date-parts":[[2016,6,23]],"date-time":"2016-06-23T01:36:53Z","timestamp":1466645813000},"page":"419-422","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Prenatal diagnosis of mosaic small supernumerary marker chromosome 17 associated with ventricular septal defect, developmental delay, and speech delay"],"prefix":"10.1016","volume":"55","author":[{"given":"Chih-Ping","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Chiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kung-Liahng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fu-Nan","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Schu-Rern","family":"Chern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peih-Shan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen-Ni","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin-Wen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun-Ping","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weu-Lin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayseen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tjog.2016.05.002_bib1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1159\/000079572","article-title":"Small supernumerary marker chromosomes (sSMC) in humans","volume":"107","author":"Liehr","year":"2004","journal-title":"Cytogenet Genome Res"},{"key":"10.1016\/j.tjog.2016.05.002_bib2","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1586\/erm.09.17","article-title":"Handling small supernumerary marker chromosomes in prenatal diagnostics","volume":"9","author":"Liehr","year":"2009","journal-title":"Expert Rev Mol Diagn"},{"key":"10.1016\/j.tjog.2016.05.002_bib3","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/978-1-59745-066-9_2","article-title":"Characterization of prenatally assessed de novo small supernumerary marker chromosomes by molecular cytogenetics","volume":"444","author":"Liehr","year":"2008","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.tjog.2016.05.002_bib4","first-page":"995","article-title":"De novo balanced chromosome rearrangements and extra marker chromosomes identified at prenatal diagnosis: clinical significance and distribution of breakpoints","volume":"49","author":"Warburton","year":"1991","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.tjog.2016.05.002_bib5","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/(SICI)1096-8628(19980203)75:4<355::AID-AJMG4>3.0.CO;2-P","article-title":"FISH and molecular study of autosomal supernumerary marker chromosomes excluding those derived from chromosomes 15 and 22: I. Results of 26 new cases","volume":"75","author":"Crolla","year":"1998","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.tjog.2016.05.002_bib6","first-page":"719","article-title":"Frequency of small supernumerary marker chromosomes in prenatal, newborn, developmentally retarded and infertility diagnostics","volume":"19","author":"Liehr","year":"2007","journal-title":"Int J Mol Med"},{"key":"10.1016\/j.tjog.2016.05.002_bib7","unstructured":"Liehr T. Small supernumerary marker chromosomes. Available at http:\/\/ssmc-tl.com\/sSMC.html. [Accessed 22 March 2016]."},{"issue":"1","key":"10.1016\/j.tjog.2016.05.002_bib8","first-page":"S37","article-title":"Potocki-Lupski syndrome and Turner syndrome in two patients with mosaicism for a marker chromosomes","volume":"19","author":"Capovia","year":"2011","journal-title":"Chromosome Res"},{"key":"10.1016\/j.tjog.2016.05.002_bib9","series-title":"Identification of de novo sSMC 17 associated with developmental delay and dysmorphic features. AABC2013, 10th Balkan congress of human genetics 2nd Alpe Adria meeting of human genetics, Bled, Slovenia 10\u201312","first-page":"p155","author":"Hovnik","year":"2013"},{"key":"10.1016\/j.tjog.2016.05.002_bib10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.psychres.2015.03.022","article-title":"A\u00a0mosaic small supernumerary marker chromosome 17 in a patient with Tourette syndrome, ADHD and intellectual disability: a case story and review of the literature","volume":"228","author":"Cornelius","year":"2015","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.tjog.2016.05.002_bib11","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1038\/ng.2681","article-title":"ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3","volume":"45","author":"Hoff","year":"2013","journal-title":"Nat Genet"},{"key":"10.1016\/j.tjog.2016.05.002_bib12","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1002\/ajmg.a.37512","article-title":"Compound heterozygous mutations in NEK8 in siblings with end-stage renal disease with hepatic and cardiac anomalies","volume":"170A","author":"Rajagopalan","year":"2016","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.tjog.2016.05.002_bib13","doi-asserted-by":"crossref","first-page":"H945","DOI":"10.1152\/ajpheart.00918.2013","article-title":"Poldip2 controls vascular smooth muscle cell migration by regulating focal adhesion turnover and force polarization","volume":"307","author":"Datla","year":"2014","journal-title":"Am J Physiol Heart Circ Physiol"}],"container-title":["Taiwanese Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1028455916300560?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1028455916300560?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T18:14:43Z","timestamp":1760897683000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1028455916300560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["S1028455916300560"],"URL":"https:\/\/doi.org\/10.1016\/j.tjog.2016.05.002","relation":{},"ISSN":["1028-4559"],"issn-type":[{"value":"1028-4559","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prenatal diagnosis of mosaic small supernumerary marker chromosome 17 associated with ventricular septal defect, developmental delay, and speech delay","name":"articletitle","label":"Article Title"},{"value":"Taiwanese Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjog.2016.05.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016, Taiwan Association of Obstetrics & Gynecology. Published by Elsevier Taiwan LLC.","name":"copyright","label":"Copyright"}]}}