{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:27:27Z","timestamp":1790872047324,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T00:00:00Z","timestamp":1589500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004861","name":"Mackay Memorial Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004861","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MMH-E-109-04"],"award-info":[{"award-number":["MMH-E-109-04"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Taiwanese Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.tjog.2020.05.023","type":"journal-article","created":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T10:55:21Z","timestamp":1594205721000},"page":"604-606","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prenatal diagnosis of mosaicism for trisomy 12 in a single colony at amniocentesis in a pregnancy with a favorable outcome"],"prefix":"10.1016","volume":"59","author":[{"given":"Chih-Ping","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao-Yun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Schu-Rern","family":"Chern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin-Wen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang-Tzu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Lin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Yi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayseen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tjog.2020.05.023_bib1","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.tjog.2013.11.001","article-title":"Interphase FISH on uncultured amniocytes at repeat amniocentesis for rapid diagnosis of true mosaicism in a case of level II mosaicism involving trisomy 21 in a single colony from an in situ culture of amniocytes","volume":"53","author":"Chen","year":"2014","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.tjog.2020.05.023_bib2","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.tjog.2016.05.005","article-title":"Rapid diagnosis of pseudomosaicism in a case of level II mosaicism for trisomy 5 in a single colony from an in situ culture of amniocytes and a review of mosaic trisomy 5 at amniocentesis","volume":"55","author":"Chen","year":"2016","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.tjog.2020.05.023_bib3","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.tjog.2017.01.007","article-title":"Prenatal diagnosis of mosaicism for trisomy 15 in a single colony at amniocentesis with a favorable fetal outcome","volume":"56","author":"Chen","year":"2017","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.tjog.2020.05.023_bib4","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.tjog.2017.05.007","article-title":"Prenatal diagnosis of mosaicism for trisomy 2 in a single colony at amniocentesis in a pregnancy with a favorable outcome","volume":"56","author":"Chen","year":"2017","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.tjog.2020.05.023_bib5","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/j.tjog.2019.09.022","article-title":"Prenatal diagnosis of mosaicism for trisomy 7 in a single colony at amniocentesis in a pregnancy with a favorable fetal outcome","volume":"58","author":"Chen","year":"2019","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.tjog.2020.05.023_bib6","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.tjog.2020.01.027","article-title":"Prenatal diagnosis of mosaicism for trisomy 11 in a single colony at amniocentesis in a pregnancy with a favorable outcome","volume":"59","author":"Chen","year":"2020","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.tjog.2020.05.023_bib7","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.tjog.2020.03.020","article-title":"Prenatal diagnosis of mosaicism for double trisomies of trisomy 11 and trisomy 12 in a single colony at amniocentesis in a pregnancy with a favorable outcome","volume":"59","author":"Chen","year":"2020","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.tjog.2020.05.023_bib8","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/(SICI)1097-0223(199703)17:3<201::AID-PD56>3.0.CO;2-H","article-title":"Rare trisomy mosaicism diagnosed in amniocytes, involving an autosome other than chromosomes 13, 18, 20, and 21: karyotype\/phenotype correlations","volume":"17","author":"Hsu","year":"1997","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.tjog.2020.05.023_bib9","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.tjog.2013.06.008","article-title":"Prenatal diagnosis of mosaic trisomy 12 associated with congenital overgrowth","volume":"52","author":"Chen","year":"2013","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.tjog.2020.05.023_bib10","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.tjog.2013.01.012","article-title":"Mosaic trisomy 12 at amniocentesis: prenatal diagnosis and molecular genetic analysis","volume":"52","author":"Chen","year":"2013","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.tjog.2020.05.023_bib11","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.tjog.2016.08.006","article-title":"Prenatal diagnosis of low-level mosaicism for trisomy 12 associated with a favorable pregnancy outcome","volume":"55","author":"Chen","year":"2016","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.tjog.2020.05.023_bib12","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.tjog.2017.01.005","article-title":"Prenatal diagnosis and molecular cytogenetic characterization of low-level mosaic trisomy 12 at amniocentesis associated with a favorable pregnancy outcome","volume":"56","author":"Chen","year":"2017","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.tjog.2020.05.023_bib13","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1139\/g77-061","article-title":"Trisomy 12 mosaicism in an infertile man","volume":"19","author":"Richer","year":"1977","journal-title":"Can J Genet Cytol"},{"key":"10.1016\/j.tjog.2020.05.023_bib14","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/ajmg.1320140308","article-title":"First report of mosaic trisomy 12 in a liveborn individual","volume":"14","author":"Patil","year":"1983","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.tjog.2020.05.023_bib15","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1136\/jmg.31.3.253","article-title":"Trisomy 12 mosaicism in a 7 year old girl with dysmorphic features and normal mental development","volume":"31","author":"English","year":"1994","journal-title":"J\u00a0Med Genet"},{"key":"10.1016\/j.tjog.2020.05.023_bib16","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1002\/pd.1970151106","article-title":"Mosaicism for trisomy 12: four cases with varying outcomes","volume":"15","author":"Bischoff","year":"1995","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.tjog.2020.05.023_bib17","first-page":"A111","article-title":"Trisomy 12 mosaicism in a girl with multiple minor anomalies","volume":"59","author":"Aughton","year":"1996","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.tjog.2020.05.023_bib18","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1002\/1096-8628(20001218)95:5<444::AID-AJMG7>3.0.CO;2-X","article-title":"Trisomy 12 mosaicism confirmed in multiple organs from a liveborn child","volume":"95","author":"DeLozier-Blanchet","year":"2000","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.tjog.2020.05.023_bib19","first-page":"173","article-title":"A\u00a0case of trisomy 12 mosaicism with pituitary malformation and polycystic ovary syndrome","volume":"17","author":"Boulard","year":"2006","journal-title":"Genet Counsel"},{"key":"10.1016\/j.tjog.2020.05.023_bib20","doi-asserted-by":"crossref","first-page":"261","DOI":"10.3109\/01443615.2010.547952","article-title":"A\u00a0case of trisomy 12 mosaicism presenting antenatally with fetal cardiomyopathy","volume":"31","author":"Parasuraman","year":"2011","journal-title":"J\u00a0Obstet Gynaecol"},{"key":"10.1016\/j.tjog.2020.05.023_bib21","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1002\/ajmg.a.35354","article-title":"Novel clinical findings in a case of postnatally diagnosed trisomy 12 mosaicism","volume":"158A","author":"Al-Hertani","year":"2012","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.tjog.2020.05.023_bib22","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1002\/ajmg.a.38194","article-title":"Clinical features of trisomy 12 mosaicism - report and review","volume":"173A","author":"Hong","year":"2017","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.tjog.2020.05.023_bib23","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1159\/000498836","article-title":"Mosaic trisomy 12 associated with overgrowth detected in fibroblast cell lines","volume":"157","author":"Gasparini","year":"2019","journal-title":"Cytogenet Genome Res"},{"key":"10.1016\/j.tjog.2020.05.023_bib24","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1002\/ajmg.a.61482","article-title":"Four children with postnatally diagnosed mosaic trisomy 12: clinical features, literature review, and current diagnostic capabilities of genetic testing","volume":"182A","author":"Hu","year":"2020","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.tjog.2020.05.023_bib25","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1089\/dna.1993.12.227","article-title":"Cytogenetic evidence of involvement of chromosome regions 15q12 and 12q15 in conditions with associated overgrowth","volume":"12","author":"Wajntal","year":"1993","journal-title":"DNA Cell Biol"},{"key":"10.1016\/j.tjog.2020.05.023_bib26","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/ajmg.a.30300","article-title":"Assisted reproductive technology and congenital overgrowth: some speculations on a case of Pallister-Killian syndrome","volume":"130A","author":"Chiurazzi","year":"2004","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.tjog.2020.05.023_bib27","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.ejmg.2006.10.008","article-title":"Duplication of (12)(pter-q13.3) combined with deletion of (22)(pter-q11.2) in a patient with features of both chromosome aberrations","volume":"50","author":"Tyshchenko","year":"2007","journal-title":"Eur J Med Genet"},{"key":"10.1016\/j.tjog.2020.05.023_bib28","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1002\/pd.2319","article-title":"Genetic considerations in the prenatal diagnosis of overgrowth syndromes","volume":"29","author":"Vora","year":"2009","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.tjog.2020.05.023_bib29","first-page":"247","article-title":"Pallister Killian syndrome: unusual significant postnatal overgrowth in a girl with otherwise typical presentation","volume":"34","author":"Frkovi\u0107","year":"2010","journal-title":"Coll Antropol"},{"key":"10.1016\/j.tjog.2020.05.023_bib30","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.3324\/haematol.2010.036897","article-title":"An unexpected transmission of von Willebrand disease type 3: the first case of maternal uniparental disomy 12","volume":"96","author":"Boisseau","year":"2011","journal-title":"Haematologica"},{"key":"10.1016\/j.tjog.2020.05.023_bib31","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.cca.2013.08.013","article-title":"Microarray analysis unmasked paternal uniparental disomy of chromosome 12 in a patient with isolated sulfite oxidase deficiency","volume":"426","author":"Cho","year":"2013","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.tjog.2020.05.023_bib32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0131157","article-title":"Detection of hereditary1,25-hydroxyvitamin D-resistant rickets caused by uniparental disomy of chromosome 12 using genome-wide single nucleotide polymorphism array","volume":"10","author":"Tamura","year":"2015","journal-title":"PloS One"}],"container-title":["Taiwanese Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1028455920301224?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1028455920301224?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T18:18:18Z","timestamp":1760897898000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1028455920301224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["S1028455920301224"],"URL":"https:\/\/doi.org\/10.1016\/j.tjog.2020.05.023","relation":{},"ISSN":["1028-4559"],"issn-type":[{"value":"1028-4559","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prenatal diagnosis of mosaicism for trisomy 12 in a single colony at amniocentesis in a pregnancy with a favorable outcome","name":"articletitle","label":"Article Title"},{"value":"Taiwanese Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjog.2020.05.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}