{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T13:06:14Z","timestamp":1792760774984,"version":"4.5.0"},"reference-count":14,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T00:00:00Z","timestamp":1625616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Taiwanese Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.tjog.2021.07.016","type":"journal-article","created":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T02:31:03Z","timestamp":1630981863000},"page":"874-877","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Long-term outcome of fetus with ameliorated cystic hygroma"],"prefix":"10.1016","volume":"60","author":[{"given":"Keiko","family":"Kagawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironori","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiho","family":"Nagayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Horie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayo","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosuke","family":"Baba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manabu","family":"Ogoyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotada","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rie","family":"Usui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihide","family":"Ohkuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeki","family":"Matsubara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tjog.2021.07.016_bib1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0146-0005(99)80042-1","article-title":"Cystic hygroma in the fetus and newborn","volume":"23","author":"Gallagher","year":"1999","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.tjog.2021.07.016_bib2","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1080\/00016340701644843","article-title":"Characteristics and outcome of fetal cystic hygroma diagnosed in the first trimester","volume":"86","author":"Graesslin","year":"2007","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.tjog.2021.07.016_bib3","first-page":"127","article-title":"Management and outcomes of cystic hygromas: experience of a tertiary center","volume":"20","author":"Orgul","year":"2017","journal-title":"J\u00a0Ultrasound"},{"key":"10.1016\/j.tjog.2021.07.016_bib4","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1002\/pd.1423","article-title":"Karyotype and outcome of fetuses diagnosed with cystic hygroma in the first trimester in relation to nuchal translucency thickness","volume":"26","author":"Kharrat","year":"2006","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.tjog.2021.07.016_bib5","doi-asserted-by":"crossref","first-page":"245e50","DOI":"10.1046\/j.1469-0705.2000.00223.x","article-title":"Prognostic value of ultrasound findings of fetal cystic hygroma detected in early pregnancy by transvaginal sonography","volume":"16","author":"Rosati","year":"2000","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.tjog.2021.07.016_bib6","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.ejogrb.2013.07.043","article-title":"Fetal cystic hygroma: the importance of natural history","volume":"170","author":"Noia","year":"2013","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.tjog.2021.07.016_bib7","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/S0002-9378(12)90906-0","article-title":"First-trimester simple hygroma: cause and outcome","volume":"168","author":"Johnson","year":"1993","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.tjog.2021.07.016_bib8","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1515\/jpme.1995.23.4.283","article-title":"First trimester diagnosis of cystic hygromata using transvaginal ultrasound and cytogenetic evaluation","volume":"23","author":"Podobnik","year":"1995","journal-title":"J\u00a0Perinat Med"},{"key":"10.1016\/j.tjog.2021.07.016_bib9","first-page":"288e94","article-title":"First-trimester septated cystic hygroma: prevalence, natural history, and pediatric outcome","volume":"106","author":"Malone","year":"2005","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.tjog.2021.07.016_bib10","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/AOG.0b013e318264f829","article-title":"First-trimester cystic hygroma: relationship of nuchal translucency thickness and outcomes","volume":"120","author":"Scholl","year":"2012","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.tjog.2021.07.016_bib11","first-page":"43","article-title":"Nuchal thickening or cystic hygromas in first- and early second-trimester fetuses: prognosis and outcome","volume":"82","author":"Nadel","year":"1993","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.tjog.2021.07.016_bib12","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1002\/pd.4799","article-title":"First trimester cystic hygroma: does early detection matter?","volume":"36","author":"Scholl","year":"2016","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.tjog.2021.07.016_bib13","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.gyobfe.2005.07.031","article-title":"Increased nuchal translucency and cystic hygroma in the first trimester: prenatal diagnosis and neonatal outcome","volume":"33","author":"Ducarme","year":"2005","journal-title":"Gynecol Obstet Fertil"},{"key":"10.1016\/j.tjog.2021.07.016_bib14","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1097\/01.AOG.0000201979.23031.32","article-title":"Cystic hygromas, nuchal edema, and nuchal translucency at 11-14 weeks of gestation","volume":"107","author":"Molina","year":"2006","journal-title":"Obstet Gynecol"}],"container-title":["Taiwanese Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1028455921001881?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1028455921001881?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T18:20:23Z","timestamp":1760898023000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1028455921001881"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S1028455921001881"],"URL":"https:\/\/doi.org\/10.1016\/j.tjog.2021.07.016","relation":{},"ISSN":["1028-4559"],"issn-type":[{"value":"1028-4559","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term outcome of fetus with ameliorated cystic hygroma","name":"articletitle","label":"Article Title"},{"value":"Taiwanese Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjog.2021.07.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}