{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T23:45:32Z","timestamp":1762299932634,"version":"build-2065373602"},"reference-count":37,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T00:00:00Z","timestamp":1630713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008903","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["MOHW109-TDU-B-212-114005"],"award-info":[{"award-number":["MOHW109-TDU-B-212-114005"]}],"id":[{"id":"10.13039\/100008903","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007404","name":"Clinical Trial Center, China Medical University Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007404","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Taiwanese Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.tjog.2021.09.002","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T18:40:17Z","timestamp":1637001617000},"page":"1047-1053","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["A short length of gonadotropin hyperstimulation is sufficient to achieve an optimal IVF outcome in advance-aged women"],"prefix":"10.1016","volume":"60","author":[{"given":"Le Tien","family":"Hsu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzu Hsuan","family":"Chin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shang Yu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan Yan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu Bin","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chia Lin","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.tjog.2021.09.002_bib1","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1093\/humrep\/dem046","article-title":"International estimates of infertility prevalence and treatment-seeking: potential need and demand for infertility medical care","volume":"22","author":"Boivin","year":"2007","journal-title":"Hum Reprod"},{"issue":"4","key":"10.1016\/j.tjog.2021.09.002_bib2","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1111\/1471-0528.14966","article-title":"Epidemiology of infertility in China: a population-based study","volume":"125","author":"Zhou","year":"2018","journal-title":"Bjog"},{"issue":"3","key":"10.1016\/j.tjog.2021.09.002_bib3","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s10815-017-1088-y","article-title":"One thousand seventy-eight autologous IVF cycles in women 45 years and older: the largest single-center cohort to date","volume":"35","author":"Gunnala","year":"2018","journal-title":"J\u00a0Assist Reprod Genet"},{"issue":"2","key":"10.1016\/j.tjog.2021.09.002_bib4","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.tjog.2019.01.006","article-title":"Cumulative live birth rate of advanced-age women more than 40 with or without poor ovarian response","volume":"58","author":"Yin","year":"2019","journal-title":"Taiwan J Obstet Gynecol"},{"issue":"3","key":"10.1016\/j.tjog.2021.09.002_bib5","doi-asserted-by":"crossref","DOI":"10.1093\/hropen\/hoaa032","article-title":"ART in Europe, 2016: results generated from European registries by ESHRE","volume":"2020","author":"Wyns","year":"2020","journal-title":"Hum Reprod Open"},{"issue":"8","key":"10.1016\/j.tjog.2021.09.002_bib6","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1093\/humrep\/deaa090","article-title":"International committee for monitoring assisted reproductive technologies world report: assisted reproductive technology 2012\u2020","volume":"35","author":"de Mouzon","year":"2020","journal-title":"Hum Reprod"},{"issue":"2","key":"10.1016\/j.tjog.2021.09.002_bib7","first-page":"1","article-title":"Assisted reproductive technology surveillance--United States, 2002","volume":"54","author":"Wright","year":"2005","journal-title":"MMWR Surveillance Summ"},{"issue":"2","key":"10.1016\/j.tjog.2021.09.002_bib8","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1093\/humupd\/dmz046","article-title":"Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis","volume":"26","author":"Zhang","year":"2020","journal-title":"Hum Reprod Update"},{"issue":"8","key":"10.1016\/j.tjog.2021.09.002_bib9","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1093\/humrep\/dem135","article-title":"Morphometric characteristics of the primordial to primary follicle transition in the human ovary in relation to age","volume":"22","author":"Westergaard","year":"2007","journal-title":"Hum Reprod"},{"issue":"3","key":"10.1016\/j.tjog.2021.09.002_bib10","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1093\/humrep\/deg138","article-title":"Do cycle disturbances explain the age-related decline of female fertility? Cycle characteristics of women aged over 40 years compared with a reference population of young women","volume":"18","author":"van Zonneveld","year":"2003","journal-title":"Hum Reprod"},{"issue":"3","key":"10.1016\/j.tjog.2021.09.002_bib11","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1530\/JOE-15-0246","article-title":"Aging-related premature luteinization of granulosa cells is avoided by early oocyte retrieval","volume":"226","author":"Wu","year":"2015","journal-title":"J\u00a0Endocrinol"},{"issue":"1","key":"10.1016\/j.tjog.2021.09.002_bib12","first-page":"23","article-title":"With low ovarian reserve, Highly Individualized Egg Retrieval (HIER) improves IVF results by avoiding premature luteinization","volume":"11","author":"Wu","year":"2018","journal-title":"J\u00a0Ovarian Res"},{"year":"1999","series-title":"In-vitro culture of human blastocyst","author":"Dk","key":"10.1016\/j.tjog.2021.09.002_bib13"},{"key":"10.1016\/j.tjog.2021.09.002_bib14","first-page":"7327","article-title":"Pregnancy outcomes after different cycle regimens for frozen-thawed embryo transfer: a retrospective study using propensity score matching","author":"Wang","year":"2020","journal-title":"Front Med"},{"issue":"3","key":"10.1016\/j.tjog.2021.09.002_bib15","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.fertnstert.2017.06.005","article-title":"The international glossary on infertility and fertility care","volume":"108","author":"Zegers-Hochschild","year":"2017","journal-title":"Fertil Steril"},{"year":"2018","series-title":"Assisted reproductive technology fertility clinic success rates report","key":"10.1016\/j.tjog.2021.09.002_bib16"},{"issue":"5","key":"10.1016\/j.tjog.2021.09.002_bib17","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/S1472-6483(10)60654-2","article-title":"Impact of duration and dose of gonadotrophins on IVF outcomes","volume":"13","author":"Martin","year":"2006","journal-title":"Reprod Biomed Online"},{"issue":"7","key":"10.1016\/j.tjog.2021.09.002_bib18","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.1093\/humrep\/des141","article-title":"The duration of pre-ovulatory serum progesterone elevation before hCG administration affects the outcome of IVF\/ICSI cycles","volume":"27","author":"Huang","year":"2012","journal-title":"Hum Reprod"},{"issue":"2","key":"10.1016\/j.tjog.2021.09.002_bib19","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ejogrb.2012.02.025","article-title":"The relationship of premature progesterone rise with serum estradiol levels and number of follicles in GnRH antagonist\/recombinant FSH-stimulated cycles","volume":"162","author":"Kyrou","year":"2012","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"6","key":"10.1016\/j.tjog.2021.09.002_bib20","doi-asserted-by":"crossref","first-page":"431","DOI":"10.3109\/09513590.2014.895984","article-title":"Timing of human chorionic gonadotropin (hCG) hormone administration in IVF\/ICSI protocols using GnRH agonist or antagonists: a systematic review and meta-analysis","volume":"30","author":"Chen","year":"2014","journal-title":"Gynecol Endocrinol"},{"issue":"3","key":"10.1016\/j.tjog.2021.09.002_bib21","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1007\/s11845-016-1526-3","article-title":"The duration of gonadotropin stimulation does not alter the clinical pregnancy rate in IVF or ICSI cycles","volume":"186","author":"Purandare","year":"2017","journal-title":"Ir J Med Sci"},{"key":"10.1016\/j.tjog.2021.09.002_bib22","first-page":"9327","article-title":"Impact of maternal age on oocyte and embryo competence","author":"Cimadomo","year":"2018","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.tjog.2021.09.002_bib23","first-page":"785108320","article-title":"Mechanisms of oocyte aneuploidy associated with advanced maternal age","author":"Mikwar","year":"2020","journal-title":"Mutat Res"},{"issue":"1","key":"10.1016\/j.tjog.2021.09.002_bib24","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1530\/jrf.0.1020123","article-title":"Association between the duration of dominance of the ovulatory follicle and pregnancy rate in beef heifers","volume":"102","author":"Mihm","year":"1994","journal-title":"J\u00a0Reprod Fertil"},{"issue":"2","key":"10.1016\/j.tjog.2021.09.002_bib25","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1530\/jrf.0.1160293","article-title":"Effect of dominant follicle persistence on follicular fluid oestradiol and inhibin and on oocyte maturation in heifers","volume":"116","author":"Mihm","year":"1999","journal-title":"J\u00a0Reprod Fertil"},{"key":"10.1016\/j.tjog.2021.09.002_bib26","first-page":"283","article-title":"Real-world menstrual cycle characteristics of more than 600,000 menstrual cycles","author":"Bull","year":"2019","journal-title":"NPJ Digit Med"},{"issue":"1","key":"10.1016\/j.tjog.2021.09.002_bib27","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0093-691X(96)00336-6","article-title":"Oocyte growth, capacitation and final maturation in cattle","volume":"47","author":"Hyttel","year":"1997","journal-title":"Theriogenology"},{"key":"10.1016\/j.tjog.2021.09.002_bib28","first-page":"2012938138","article-title":"Biology and biotechnology of follicle development","author":"Palma","year":"2012","journal-title":"Sci World J"},{"issue":"4","key":"10.1016\/j.tjog.2021.09.002_bib29","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/BF02212930","article-title":"In\u00a0vitro maturation and fertilization of oocytes isolated from aged mice: a strategy to rescue valuable genetic resources","volume":"12","author":"Eppig","year":"1995","journal-title":"J\u00a0Assist Reprod Genet"},{"issue":"6","key":"10.1016\/j.tjog.2021.09.002_bib30","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.rbmo.2020.02.005","article-title":"The association between follicle size and oocyte development as a function of final follicular maturation triggering","volume":"40","author":"Mohr-Sasson","year":"2020","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.tjog.2021.09.002_bib31","first-page":"85","article-title":"Developmental changes in cells and matrix during follicle growth","author":"Rodgers","year":"1998","journal-title":"Gametes Dev Funct"},{"issue":"1","key":"10.1016\/j.tjog.2021.09.002_bib32","first-page":"1","article-title":"Comparative analysis of follicle morphology and oocyte diameter in four mammalian species (mouse, hamster, pig, and human)","volume":"3","author":"Griffin","year":"2006","journal-title":"J\u00a0Exp Clin Assist Reprod"},{"issue":"1","key":"10.1016\/j.tjog.2021.09.002_bib33","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1095\/biolreprod.104.032003","article-title":"Follicle-stimulating hormone affects metaphase I chromosome alignment and increases aneuploidy in mouse oocytes matured in\u00a0vitro","volume":"72","author":"Roberts","year":"2005","journal-title":"Biol Reprod"},{"issue":"5","key":"10.1016\/j.tjog.2021.09.002_bib34","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/S1472-6483(10)61163-7","article-title":"FSH: what is the highest dose for ovarian stimulation that makes sense on an evidence-based level?","volume":"11","author":"Dorn","year":"2005","journal-title":"Reprod Biomed Online"},{"issue":"1","key":"10.1016\/j.tjog.2021.09.002_bib35","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1210\/endo.137.1.8536637","article-title":"Proliferation of microvascular endothelial cells in the primate corpus luteum during the menstrual cycle and simulated early pregnancy","volume":"137","author":"Christenson","year":"1996","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.tjog.2021.09.002_bib36","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1111\/j.1447-0756.2003.00166.x","article-title":"Premature luteinization defined as progesterone estradiol ratio >1 on hCG administration day seems to adversely affect clinical outcome in long gonadotropin-releasing hormone agonist cycles","volume":"30","author":"Oz\u00e7akir","year":"2004","journal-title":"J\u00a0Obstet Gynaecol Res"},{"issue":"7","key":"10.1016\/j.tjog.2021.09.002_bib37","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1093\/molehr\/gas008","article-title":"Ovarian reserve status in young women is associated with altered gene expression in membrana granulosa cells","volume":"18","author":"Skiadas","year":"2012","journal-title":"Mol Hum Reprod"}],"container-title":["Taiwanese Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1028455921002424?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1028455921002424?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T18:19:27Z","timestamp":1760897967000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1028455921002424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S1028455921002424"],"URL":"https:\/\/doi.org\/10.1016\/j.tjog.2021.09.002","relation":{},"ISSN":["1028-4559"],"issn-type":[{"type":"print","value":"1028-4559"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A short length of gonadotropin hyperstimulation is sufficient to achieve an optimal IVF outcome in advance-aged women","name":"articletitle","label":"Article Title"},{"value":"Taiwanese Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjog.2021.09.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}