{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T18:41:15Z","timestamp":1760899275369,"version":"build-2065373602"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T00:00:00Z","timestamp":1636761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Taiwanese Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.tjog.2021.11.028","type":"journal-article","created":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T18:22:10Z","timestamp":1644949330000},"page":"157-162","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prenatal diagnosis of de novo isochromosome 4p with an unbalanced t(4;9) translocation in a fetus with congenital anomalies: A case report and literature review"],"prefix":"10.1016","volume":"61","author":[{"given":"Yan-Yi","family":"Yao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-Cheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Bi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.tjog.2021.11.028_bib1","first-page":"127","article-title":"De novo trisomy 4p by 4p isochromosome","volume":"19","author":"Andr\u00e9","year":"1976","journal-title":"Ann Genet"},{"issue":"1","key":"10.1016\/j.tjog.2021.11.028_bib2","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1002\/ajmg.a.30084","article-title":"A\u00a0new patient with pure trisomy 4p resulting from isochromosome formation and whole arm translocation","volume":"128A","author":"Zahed","year":"2004","journal-title":"Am J Med Genet A"},{"issue":"4","key":"10.1016\/j.tjog.2021.11.028_bib3","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1159\/000371606","article-title":"Instability of isochromosome 4p in a child with pure trisomy 4p syndrome features and entire 4q-arm translocation","volume":"144","author":"Pota","year":"2014","journal-title":"Cytogenet Genome Res"},{"issue":"6","key":"10.1016\/j.tjog.2021.11.028_bib4","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/BF02029349","article-title":"Clinical manifestations of trisomy 4p syndrome","volume":"154","author":"Patel","year":"1995","journal-title":"Eur J Pediatr"},{"issue":"2","key":"10.1016\/j.tjog.2021.11.028_bib5","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s00381-015-2957-2","article-title":"Clinical and neuroradiological features of the 9p deletion syndrome","volume":"32","author":"Spazzapan","year":"2016","journal-title":"Childs Nerv Syst"},{"issue":"1","key":"10.1016\/j.tjog.2021.11.028_bib6","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/ajmg.a.30535","article-title":"A\u00a0patient with isochromosome 18q, radial-thumb aplasia, thrombocytopenia, and an unbalanced 10;18 chromosome translocation","volume":"133A","author":"Sahoo","year":"2005","journal-title":"Am J Med Genet A"},{"issue":"5","key":"10.1016\/j.tjog.2021.11.028_bib7","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1034\/j.1399-0004.1999.550512.x","article-title":"Pure trisomy 10p involving an isochromosome 10p","volume":"55","author":"Berend","year":"1999","journal-title":"Clin Genet"},{"issue":"3","key":"10.1016\/j.tjog.2021.11.028_bib8","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/pd.1102","article-title":"Prenatal diagnosis of trisomy 4p: a new locus for holoprosencephaly?","volume":"25","author":"Karmous-Benailly","year":"2005","journal-title":"Prenat Diagn"},{"issue":"6","key":"10.1016\/j.tjog.2021.11.028_bib9","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1399-0004.1977.tb00953.x","article-title":"Trisomy 4p: five new observations and overview","volume":"12","author":"Dallapiccola","year":"1977","journal-title":"Clin Genet"},{"issue":"4","key":"10.1016\/j.tjog.2021.11.028_bib10","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1002\/ajmg.a.33916","article-title":"Microduplication of 4p16.3 due to an unbalanced translocation resulting in a mild phenotype","volume":"155A","author":"Carmany","year":"2011","journal-title":"Am J Med Genet A"},{"issue":"9","key":"10.1016\/j.tjog.2021.11.028_bib11","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1002\/ajmg.a.36099","article-title":"Segregation of a 4p16.3 duplication with a characteristic appearance, macrocephaly, speech delay and mild intellectual disability in a 3-generation family","volume":"161A","author":"Sch\u00f6newolf-Greulich","year":"2013","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.tjog.2021.11.028_bib12","doi-asserted-by":"crossref","first-page":"561","DOI":"10.3389\/fgene.2020.00561","article-title":"Candidate genes associated with neurological findings in a patient with trisomy 4p16.3 and monosomy 5p15.2","volume":"11","author":"Corr\u00eaa","year":"2020","journal-title":"Front Genet"},{"issue":"9","key":"10.1016\/j.tjog.2021.11.028_bib13","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1002\/ajmg.a.35489","article-title":"Chromosome 9p deletion syndrome and sex reversal: novel findings and redefinition of the critically deleted regions","volume":"158A","author":"Onesimo","year":"2012","journal-title":"Am J Med Genet A"},{"issue":"6","key":"10.1016\/j.tjog.2021.11.028_bib14","doi-asserted-by":"crossref","first-page":"619","DOI":"10.4103\/1008-682X.194420","article-title":"Sex determination and maintenance: the role of DMRT1 and FOXL2","volume":"19","author":"Huang","year":"2017","journal-title":"Asian J Androl"},{"issue":"3","key":"10.1016\/j.tjog.2021.11.028_bib15","doi-asserted-by":"crossref","first-page":"272","DOI":"10.4274\/balkanmedj.2017.0378","article-title":"Haploinsufficiency of the DMRT gene cluster in a case with 46,XY ovotesticular disorder of sexual development","volume":"35","author":"Eser","year":"2018","journal-title":"Balkan Med J"},{"issue":"2\u20133","key":"10.1016\/j.tjog.2021.11.028_bib16","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1159\/000445862","article-title":"Ring chromosome 9 and chromosome 9p deletion syndrome in a patient associated with developmental delay: a case report and review of the literature","volume":"148","author":"Sivasankaran","year":"2016","journal-title":"Cytogenet Genome Res"},{"issue":"9","key":"10.1016\/j.tjog.2021.11.028_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1002278","article-title":"Heterozygous mutations of FREM1 are associated with an increased risk of isolated metopic craniosynostosis in humans and mice","volume":"7","author":"Vissers","year":"2011","journal-title":"PLoS Genet"},{"issue":"4","key":"10.1016\/j.tjog.2021.11.028_bib18","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1399-0004.1987.tb03308.x","article-title":"Isochromosome (18q) in siblings","volume":"32","author":"Kr\u00fcger","year":"1987","journal-title":"Clin Genet"}],"container-title":["Taiwanese Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1028455921003326?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1028455921003326?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T18:20:17Z","timestamp":1760898017000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1028455921003326"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["S1028455921003326"],"URL":"https:\/\/doi.org\/10.1016\/j.tjog.2021.11.028","relation":{},"ISSN":["1028-4559"],"issn-type":[{"type":"print","value":"1028-4559"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prenatal diagnosis of de novo isochromosome 4p with an unbalanced t(4;9) translocation in a fetus with congenital anomalies: A case report and literature review","name":"articletitle","label":"Article Title"},{"value":"Taiwanese Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjog.2021.11.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}