{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T15:29:00Z","timestamp":1793287740294,"version":"4.5.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Taiwanese Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.tjog.2025.10.011","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T22:55:38Z","timestamp":1777071338000},"page":"520-525","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["First trimester pre-eclampsia screening using FMF-UtA-PAPPA algorithm in Hong Kong: A low-cost alternative to PlGF"],"prefix":"10.1016","volume":"65","author":[{"given":"Suet Yin","family":"Ho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linus Lin Tai","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin Wai","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10053","key":"10.1016\/j.tjog.2025.10.011_bib1","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1016\/S0140-6736(16)31470-2","article-title":"Global, regional, and national levels of maternal mortality, 1990\u20132015: a systematic analysis for the global Burden of Disease Study 2015","volume":"388","author":"Kassebaum","year":"2016","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.tjog.2025.10.011_bib2","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1002\/uog.17455","article-title":"Multicenter screening for pre-eclampsia by maternal factors and biomarkers at 11\u201313 weeks' gestation: comparison with NICE guidelines and ACOG recommendations","volume":"49","author":"O'Gorman","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"3","key":"10.1016\/j.tjog.2025.10.011_bib3","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1002\/ijgo.12741","article-title":"Good clinical practice advice: first trimester screening and prevention of pre-eclampsia in singleton pregnancy","volume":"144","year":"2019","journal-title":"Int J Gynecol Obstet"},{"issue":"6","key":"10.1016\/j.tjog.2025.10.011_bib4","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1002\/uog.17399","article-title":"Accuracy of competing-risks model in screening for pre-eclampsia by maternal factors and biomarkers at 11\u201313 weeks' gestation","volume":"49","author":"O'Gorman","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"5","key":"10.1016\/j.tjog.2025.10.011_bib5","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1111\/jog.15908","article-title":"First-trimester preterm preeclampsia prediction model for prevention with low-dose aspirin","volume":"50","author":"Pooh","year":"2024","journal-title":"J Obstet Gynaecol"},{"issue":"1","key":"10.1016\/j.tjog.2025.10.011_bib6","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/jog.14524","article-title":"Current update of first trimester preeclampsia screening in Asia","volume":"47","author":"Lin","year":"2021","journal-title":"J Obstet Gynaecol"},{"issue":"16","key":"10.1016\/j.tjog.2025.10.011_bib7","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1161\/CIRCULATIONAHA.124.069907","article-title":"Implementation of first-trimester screening and prevention of preeclampsia: a stepped wedge cluster-randomized trial in Asia","volume":"150","author":"Nguyen-Hoang","year":"2024","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.tjog.2025.10.011_bib8","doi-asserted-by":"crossref","first-page":"650.e1","DOI":"10.1016\/j.ajog.2019.09.041","article-title":"Prospective evaluation of screening performance of first-trimester prediction models for preterm preeclampsia in an Asian population","volume":"221","author":"Chaemsaithong","year":"2019","journal-title":"Am J Obstet Gynecol"},{"issue":"4","key":"10.1016\/j.tjog.2025.10.011_bib9","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1002\/uog.18816","article-title":"ASPRE trial: performance of screening for preterm pre-eclampsia","volume":"50","author":"Rolnik","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"6","key":"10.1016\/j.tjog.2025.10.011_bib10","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1002\/uog.5331","article-title":"Screening for trisomy 21 by maternal age, fetal nuchal translucency thickness, free beta-human chorionic gonadotropin and pregnancy-associated plasma protein-A","volume":"31","author":"Kagan","year":"2008","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.tjog.2025.10.011_bib11","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/1471-0528.16361","article-title":"Implementation of routine first trimester combined screening for pre-eclampsia: a clinical effectiveness study","volume":"128","author":"Guy","year":"2021","journal-title":"BJOG"},{"issue":"2","key":"10.1016\/j.tjog.2025.10.011_bib12","first-page":"101","article-title":"Prospective assessment of the Hong Kong Hospital Authority universal Down syndrome screening programme","volume":"19","author":"Sahota","year":"2013","journal-title":"Hong Kong Med J"},{"key":"10.1016\/j.tjog.2025.10.011_bib13","series-title":"Risk assessment: risk for preeclampsia - 11+0 to 14+1 weeks","year":"2025"},{"key":"10.1016\/j.tjog.2025.10.011_bib14","series-title":"Hypertension in pregnancy: diagnosis and management","year":"2019"},{"issue":"8","key":"10.1016\/j.tjog.2025.10.011_bib15","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1111\/1471-0528.17096","article-title":"Serum PlGF compared with PAPP-A in first trimester screening for preterm pre-eclampsia: adjusting for the effect of aspirin treatment","volume":"129","author":"Wright","year":"2022","journal-title":"BJOG"},{"issue":"2","key":"10.1016\/j.tjog.2025.10.011_bib16","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/1471-0528.17598","article-title":"First trimester screening for pre-eclampsia and targeted aspirin prophylaxis: a cost-effectiveness cohort study","volume":"131","author":"Nzelu","year":"2024","journal-title":"BJOG"},{"issue":"6","key":"10.1016\/j.tjog.2025.10.011_bib17","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1002\/uog.19039","article-title":"Comparison of diagnostic accuracy of early screening for pre-eclampsia by NICE guidelines and a method combining maternal factors and biomarkers: results of SPREE","volume":"51","author":"Tan","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"7491","key":"10.1016\/j.tjog.2025.10.011_bib18","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1136\/bmj.38380.674340.E0","article-title":"Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies","volume":"330","author":"Duckitt","year":"2005","journal-title":"BMJ"},{"issue":"6","key":"10.1016\/j.tjog.2025.10.011_bib19","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1213\/ANE.0000000000000705","article-title":"Outcomes for extremely premature infants","volume":"120","author":"Glass","year":"2015","journal-title":"Anesth Analg"},{"issue":"2","key":"10.1016\/j.tjog.2025.10.011_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2022.100815","article-title":"The implementation of preeclampsia screening and prevention (IMPRESS) study","volume":"5","author":"Johnson","year":"2023","journal-title":"Am J Obstet Gynecol MFM"},{"key":"10.1016\/j.tjog.2025.10.011_bib21","series-title":"The fetal medicine foundation. FMF certification: preeclampsia screening","year":"2025"},{"issue":"3","key":"10.1016\/j.tjog.2025.10.011_bib22","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ajog.2017.11.561","article-title":"Aspirin for the prevention of preterm and term preeclampsia: systematic review and metaanalysis","volume":"218","author":"Roberge","year":"2018","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.tjog.2025.10.011_bib23","doi-asserted-by":"crossref","first-page":"204.e1","DOI":"10.1016\/j.ajog.2020.08.008","article-title":"Pregnancy outcomes in nulliparous women with positive first-trimester preterm preeclampsia screening test: the great obstetrical syndromes cohort study","volume":"224","author":"Boutin","year":"2021","journal-title":"Am J Obstet Gynecol"}],"container-title":["Taiwanese Journal of Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1028455926001002?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1028455926001002?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T21:35:36Z","timestamp":1778794536000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1028455926001002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S1028455926001002"],"URL":"https:\/\/doi.org\/10.1016\/j.tjog.2025.10.011","relation":{},"ISSN":["1028-4559"],"issn-type":[{"value":"1028-4559","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"First trimester pre-eclampsia screening using FMF-UtA-PAPPA algorithm in Hong Kong: A low-cost alternative to PlGF","name":"articletitle","label":"Article Title"},{"value":"Taiwanese Journal of Obstetrics and Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjog.2025.10.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}