{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:29:31Z","timestamp":1786116571384,"version":"build-2736575974"},"reference-count":58,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T00:00:00Z","timestamp":1733184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008483","name":"NOMIS Stiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008483","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004328","name":"Genentech","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004328","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004337","name":"Roche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004337","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001109","name":"Flinn Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001109","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007637","name":"Departamento Administrativo de Ciencia, Tecnolog\u00eda e Innovaci\u00f3n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007637","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010292","name":"Banner Alzheimer\u2019s Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010292","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Prevention of Alzheimer's Disease"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.tjpad.2024.100030","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T06:39:24Z","timestamp":1737614364000},"page":"100030","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Basal forebrain global functional connectivity is preserved in asymptomatic presenilin-1 E280A mutation carriers: Results from the Colombia cohort"],"prefix":"10.1016","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8861-3183","authenticated-orcid":false,"given":"Alice","family":"Grazia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3353-3167","authenticated-orcid":false,"given":"Martin","family":"Dyrba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8075-4253","authenticated-orcid":false,"given":"Nunzio","family":"Pomara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna G.","family":"Temp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2600-9022","authenticated-orcid":false,"given":"Michel J.","family":"Grothe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan J.","family":"Teipel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.tjpad.2024.100030_bib0001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s13670-018-0234-4","article-title":"Recent advances in cholinergic imaging and cognitive decline-Revisiting the cholinergic hypothesis of dementia","volume":"7","author":"Bohnen","year":"2018","journal-title":"Curr Geriatr Rep"},{"key":"10.1016\/j.tjpad.2024.100030_bib0002","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0079-6123(08)62112-3","article-title":"Chapter 28 The systems-level organization of cholinergic innervation in the human cerebral cortex and its alterations in Alzheimer's disease","volume":"109","author":"Mesulam","year":"1996","journal-title":"Prog Brain Res"},{"issue":"9","key":"10.1016\/j.tjpad.2024.100030_bib0003","article-title":"Atrophy of the Cholinergic Basal Forebrain Over the Adult Age Range and in Early Stages of Alzheimer's Disease","volume":"71","author":"Groethe","year":"2012","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.tjpad.2024.100030_bib0004","doi-asserted-by":"crossref","first-page":"13249","DOI":"10.1038\/ncomms13249","article-title":"Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer's pathology","volume":"7","author":"Schmitz","year":"2016","journal-title":"Nat Commun"},{"issue":"3","key":"10.1016\/j.tjpad.2024.100030_bib0005","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1002\/hbm.24417","article-title":"The corticotopic organization of the human basal forebrain as revealed by regionally selective functional connectivity profiles","volume":"40","author":"Fritz","year":"2018","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.tjpad.2024.100030_bib0006","article-title":"Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer's disease spectrum","volume":"28","author":"Herdick","year":"2020","journal-title":"NeuroImage: Clinical"},{"key":"10.1016\/j.tjpad.2024.100030_bib0007","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1148\/radiol.2018180268","article-title":"Relationship between basal forebrain resting-state functional connectivity and brain amyloid-b deposition in cognitively intact older adults with subjective memory complaints","volume":"290","author":"Chiesa","year":"2019","journal-title":"Radiology"},{"issue":"1","key":"10.1016\/j.tjpad.2024.100030_bib0008","doi-asserted-by":"crossref","DOI":"10.1186\/alzrt59","article-title":"Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease","volume":"3","author":"Bateman","year":"2011","journal-title":"Alzheimer Res Ther"},{"issue":"2","key":"10.1016\/j.tjpad.2024.100030_bib0009","article-title":"Descripcion de una familia con demencia presenil tipo Alzheimer \/Description of a family with presenile dementia type Alzheimer","volume":"12","author":"Cornejo","year":"1987","journal-title":"Acta M\u00e9dica Colombiana"},{"key":"10.1016\/j.tjpad.2024.100030_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/S1474-4422(10)70323-9","article-title":"Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study","volume":"10","author":"Acosta-Baena","year":"2011","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.tjpad.2024.100030_bib0011","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.trci.2018.02.002","volume":"4","author":"Tariot","year":"2018","journal-title":"Alzheimer Dement (N Y)"},{"issue":"12","key":"10.1016\/j.tjpad.2024.100030_bib0012","first-page":"70227","article-title":"Florbetapir PET analysis of amyloid-\u03b2 deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study","volume":"11","author":"Fleisher","year":"2013","journal-title":"Lancet Neurol"},{"issue":"11","key":"10.1016\/j.tjpad.2024.100030_bib0013","doi-asserted-by":"crossref","first-page":"655","DOI":"10.33588\/rn.4511.2007086","article-title":"Validity and reliability of the CERAD-Col neuropsychological battery","volume":"45","author":"Aguirre-Acevedo","year":"2007","journal-title":"Rev Neurol"},{"key":"10.1016\/j.tjpad.2024.100030_bib0014","article-title":"Neural networks in autosomal dominant Alzheimer's disease: insights from functional magnetic resonance imaging studies","volume":"14","author":"Qiu","year":"2022","journal-title":"Front Aging (Albany NY) Neurosci"},{"issue":"8","key":"10.1016\/j.tjpad.2024.100030_bib0015","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1212\/WNL.0b013e3182a1aafe","article-title":"Impaired default network functional connectivity in autosomal dominant Alzheimer disease","volume":"81","author":"Chhatwal","year":"2013","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/j.tjpad.2024.100030_bib0016","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.3233\/JAD-191065","article-title":"Functional connectivity of default mode network subsystems in the presymptomatic stage of autosomal dominant Alzheimer's disease","volume":"73","author":"Zhao","year":"2020","journal-title":"J Alzheimer Dis"},{"issue":"1","key":"10.1016\/j.tjpad.2024.100030_bib0017","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s13195-019-0572-2","article-title":"Effects of gene mutation and disease progression on representative neural circuits in familial Alzheimer's disease","volume":"12","author":"Quan","year":"2020","journal-title":"Alzheimer Res Ther"},{"issue":"3","key":"10.1016\/j.tjpad.2024.100030_bib0018","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1001\/jamaneurol.2014.3314","article-title":"Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study","volume":"72","author":"Fleisher","year":"2015","journal-title":"JAMA Neurol"},{"issue":"6","key":"10.1016\/j.tjpad.2024.100030_bib0019","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1002\/ana.22105","article-title":"Hippocampal hyperactivation in presymptomatic familial Alzheimer's disease","volume":"68","author":"Quiroz","year":"2010","journal-title":"Ann Neurol"},{"key":"10.1016\/j.tjpad.2024.100030_bib0020","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1002\/alz.12843","article-title":"A public resource of baseline data from the Alzheimer\u2018s Prevention Initiative Autosomal-Dominant Alzheimer\u2018s Disease Trial","volume":"19","author":"Reiman","year":"2022","journal-title":"Alzheimer Dement"},{"key":"10.1016\/j.tjpad.2024.100030_bib0021","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/(SICI)1098-1004(1997)10:3<186::AID-HUMU2>3.0.CO;2-H","article-title":"E280A PS-1 mutation causes Alzheimer's disease but age of onset is not modified by ApoE alleles","volume":"10","author":"Lendon","year":"1997","journal-title":"Hum Mutat"},{"key":"10.1016\/j.tjpad.2024.100030_bib0022","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1002\/alz.12109","article-title":"Baseline demographic, clinical, and cognitive characteristics of the Alzheimer's Prevention Initiative (API) Autosomal-Dominant Alzheimer's Disease Colombia Trial","volume":"16","author":"Rios-Romenets","year":"2020","journal-title":"Alzheimer Dement"},{"issue":"3","key":"10.1016\/j.tjpad.2024.100030_bib0023","doi-asserted-by":"crossref","DOI":"10.1002\/mrm.1910350312","article-title":"Movement-related effects in fMRI time-series","volume":"35","author":"Friston","year":"1996","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.tjpad.2024.100030_bib0024","article-title":"Comparing data-driven physiological denoising approaches for resting-state fMRI: implications for the study of aging","volume":"18","author":"Golestani","year":"2024","journal-title":"Front (Boulder) Front Neurosci"},{"key":"10.1016\/j.tjpad.2024.100030_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2019.116231","article-title":"Model-based physiological noise removal in fast fMRI","volume":"205","author":"Agrawal","year":"2020","journal-title":"Neuroimage"},{"key":"10.1016\/j.tjpad.2024.100030_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2020.116614","article-title":"Identifying and removing widespread signal deflections from fMRI data: rethinking the global signal regression problem","volume":"212","author":"Aquino","year":"2020","journal-title":"Neuroimage"},{"key":"10.1016\/j.tjpad.2024.100030_bib0027","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.neuroimage.2017.02.036","article-title":"The global signal in fMRI: nuisance or Information?","volume":"150","author":"Liu","year":"2017","journal-title":"Neuroimage"},{"key":"10.1016\/j.tjpad.2024.100030_bib0028","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1006\/nimg.2002.1132","article-title":"Improved optimization for the robust and accurate linear registration and motion correction of brain images","volume":"17","author":"Jenkinson","year":"2002","journal-title":"Neuroimage"},{"issue":"3","key":"10.1016\/j.tjpad.2024.100030_bib0029","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1016\/j.neuroimage.2011.10.018","article-title":"Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion","volume":"59","author":"Power","year":"2012","journal-title":"Neuroimage"},{"issue":"6","key":"10.1016\/j.tjpad.2024.100030_bib0030","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1038\/s41386-020-0624-0","article-title":"Evaluating global brain connectivity as an imaging marker for depression: influence of preprocessing strategies and placebo-controlled ketamine treatment","volume":"45","author":"Kraus","year":"2020","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"10.1016\/j.tjpad.2024.100030_bib0031","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1007\/s11682-016-9599-1","article-title":"Resting-state global functional connectivity as a biomarker of cognitive reserve in mild cognitive impairment","volume":"11","author":"Franzmeier","year":"2017","journal-title":"Brain Imaging Behav"},{"issue":"26","key":"10.1016\/j.tjpad.2024.100030_bib0032","doi-asserted-by":"crossref","first-page":"8988","DOI":"10.1523\/JNEUROSCI.0536-12.2012","article-title":"Global connectivity of prefrontal cortex predicts cognitive control and intelligence","volume":"32","author":"Cole","year":"2012","journal-title":"J Neurosci"},{"issue":"4","key":"10.1016\/j.tjpad.2024.100030_bib0033","first-page":"1903","article-title":"Regional homogeneity approach to fMRI data analysis","volume":"20","author":"Zang","year":"2003","journal-title":"Neuroimage"},{"key":"10.1016\/j.tjpad.2024.100030_bib0034","article-title":"Advances and pitfalls in the analysis and interpretation of resting-state FMRI data","volume":"4","author":"Cole","year":"2010","journal-title":"Front Syst Neurosci"},{"key":"10.1016\/j.tjpad.2024.100030_bib0035","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.bbr.2017.01.027","article-title":"Modulation on brain gray matter activity and white matter integrity by APOE \u03b54 risk gene in cognitively intact elderly: a multimodal neuroimaging study","volume":"322","author":"Cai","year":"2017","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.tjpad.2024.100030_bib0036","article-title":"Using regional homogeneity to reveal altered spontaneous activity in patients with mild cognitive impairment","author":"Wang","year":"2015","journal-title":"Biomed Res Int"},{"issue":"2","key":"10.1016\/j.tjpad.2024.100030_bib0037","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1016\/j.neuroimage.2011.08.049","article-title":"Altered spontaneous activity in Alzheimer's disease and mild cognitive impairment revealed by Regional Homogeneity","volume":"59","author":"Zhang","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.tjpad.2024.100030_bib0038","first-page":"15","article-title":"Changes of regional neural activity homogeneity in preclinical Alzheimer's disease: compensation and dysfunction","author":"Zhang","year":"2021","journal-title":"Front Neurosci"},{"key":"10.1016\/j.tjpad.2024.100030_bib0039","series-title":"Proceedings of 5-th Berkeley Symposium on Mathematical Statistics and Probability","article-title":"Some methods for classification and analysis of multivariate observations","author":"MacQueen","year":"1967"},{"key":"10.1016\/j.tjpad.2024.100030_bib0040","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1002\/alz.12374","article-title":"How Bayesian statistics may help answer some of the controversial questions in clinical research on Alzheimer's disease","volume":"17","author":"Temp","year":"2021","journal-title":"Alzheimer Dement"},{"issue":"1","key":"10.1016\/j.tjpad.2024.100030_bib0041","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3758\/s13423-017-1343-3","article-title":"Bayesian inference for psychology. Part I: theoretical advantages and practical ramifications","volume":"25","author":"Wagenmakers","year":"2018","journal-title":"Psychon Bull Rev"},{"key":"10.1016\/j.tjpad.2024.100030_bib0042","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jhealeco.2007.09.009","article-title":"Two-stage residual inclusion estimation: addressing endogeneity in health econometric modeling","volume":"27","author":"Terza","year":"2008","journal-title":"J Health N Hav Econ."},{"key":"10.1016\/j.tjpad.2024.100030_bib0043","doi-asserted-by":"crossref","first-page":"813","DOI":"10.3758\/s13423-020-01798-5","article-title":"The JASP guidelines for conducting and reporting a Bayesian analysis","volume":"28","author":"van Doorn","year":"2021","journal-title":"Psychon Bull Rev"},{"issue":"5","key":"10.1016\/j.tjpad.2024.100030_bib0044","doi-asserted-by":"crossref","DOI":"10.1093\/braincomms\/fcad262","article-title":"for the Alzheimer's Disease Neuroimaging Initiative. Basal forebrain activity predicts functional degeneration in the entorhinal cortex in Alzheimer's disease","volume":"5","author":"Mieling","year":"2023","journal-title":"Brain commun"},{"issue":"7","key":"10.1016\/j.tjpad.2024.100030_bib0045","doi-asserted-by":"crossref","DOI":"10.1097\/00001756-200105250-00018","article-title":"Survival and plasticity of basal forebrain cholinergic systems in mice transgenic for presenilin-1 and amyloid precursor protein mutant genes","volume":"12","author":"Hernandez","year":"2001","journal-title":"Neuroreport"},{"issue":"3","key":"10.1016\/j.tjpad.2024.100030_bib0046","doi-asserted-by":"crossref","DOI":"10.1089\/brain.2020.0808","article-title":"Resting-state functional connectivity disruption as a pathological biomarker in autosomal dominant Alzheimer disease","volume":"11","author":"Smith","year":"2021","journal-title":"Brain Connect"},{"issue":"1","key":"10.1016\/j.tjpad.2024.100030_bib0047","doi-asserted-by":"crossref","first-page":"e30","DOI":"10.1212\/WNL.0000000000008696","article-title":"Plasma tau correlates with basal forebrain atrophy rates in people at risk for Alzheimer disease","volume":"94","author":"Cavedo","year":"2020","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/j.tjpad.2024.100030_bib0048","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1093\/cercor\/bhz224","article-title":"Atrophy of basal forebrain initiates with tau pathology in individuals at risk for Alzheimer's disease","volume":"30","author":"Cantero","year":"2020","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.tjpad.2024.100030_bib0049","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2022.119511","article-title":"Covariance-based vs. correlation-based functional connectivity dissociates healthy aging from Alzheimer disease","volume":"261","author":"Strain","year":"2022","journal-title":"Neuroimage"},{"key":"10.1016\/j.tjpad.2024.100030_bib0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.ceca.2021.102362","article-title":"Mitochondrial dysfunction in neurodegenerative diseases: a focus on iPSC-derived neuronal models","volume":"94","author":"Trombetta-Lima","year":"2021","journal-title":"Cell Calc"},{"key":"10.1016\/j.tjpad.2024.100030_bib0051","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.neuint.2009.08.005","article-title":"Regional brain metabolism with cytochrome c oxidase histochemistry in a PS1\/A246E mouse model of autosomal dominant Alzheimer's disease: correlations with behavior and oxidative stress","volume":"55","author":"Strazielle","year":"2009","journal-title":"Neurochem Int"},{"issue":"11268","key":"10.1016\/j.tjpad.2024.100030_bib0052","article-title":"Basal forebrain volume and metabolism in carriers of the Colombian mutation for autosomal dominant Alzheimer's disease","volume":"14","author":"Teipel","year":"2024","journal-title":"Sci Rep"},{"key":"10.1016\/j.tjpad.2024.100030_bib0053","doi-asserted-by":"crossref","DOI":"10.1038\/s41591-023-02318-3","article-title":"Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man","volume":"29","author":"Lopera","year":"2023","journal-title":"Nat Med"},{"key":"10.1016\/j.tjpad.2024.100030_bib0054","article-title":"Differences changes in cerebellar functional connectivity between mild cognitive impairment and alzheimer's disease: a seed-based approach","volume":"12","author":"Fanyu","year":"2021","journal-title":"Front Neurol"},{"key":"10.1016\/j.tjpad.2024.100030_bib0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2021.102749","article-title":"PET evidence of preclinical cerebellar amyloid plaque deposition in autosomal dominant Alzheimer's disease-causing Presenilin-1 E280A mutation carriers","volume":"31","author":"Ghisays","year":"2021","journal-title":"Neuroimage Clin"},{"issue":"12","key":"10.1016\/j.tjpad.2024.100030_bib0056","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21124443","article-title":"Heavy Tau burden with subtle amyloid \u03b2 accumulation in the cerebral cortex and cerebellum in a case of familial Alzheimer's disease with APP Osaka Mutation","volume":"21","author":"Shimada","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.tjpad.2024.100030_bib0057","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s13195-018-0424-5","article-title":"Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzheimer's disease (BLAZE)","volume":"10","author":"Salloway","year":"2018","journal-title":"Alzheimers Res Ther"},{"issue":"7","key":"10.1016\/j.tjpad.2024.100030_bib0058","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1038\/s41591-021-01369-8","article-title":"A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease","volume":"27","author":"Salloway","year":"2021","journal-title":"Nat Med"}],"container-title":["The Journal of Prevention of Alzheimer's Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2274580724006228?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2274580724006228?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T10:48:38Z","timestamp":1786013318000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2274580724006228"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":58,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S2274580724006228"],"URL":"https:\/\/doi.org\/10.1016\/j.tjpad.2024.100030","relation":{},"ISSN":["2274-5807"],"issn-type":[{"value":"2274-5807","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Basal forebrain global functional connectivity is preserved in asymptomatic presenilin-1 E280A mutation carriers: Results from the Colombia cohort","name":"articletitle","label":"Article Title"},{"value":"The Journal of Prevention of Alzheimer's Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjpad.2024.100030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Masson SAS on behalf of SERDI Publisher.","name":"copyright","label":"Copyright"}],"article-number":"100030"}}