{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T17:10:20Z","timestamp":1793985020745,"version":"4.8.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:00:00Z","timestamp":1773187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005224","name":"Deutsches Zentrum f\u00fcr Neurodegenerative Erkrankungen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005224","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008131","name":"Rheinische Friedrich-Wilhelms-Universit\u00e4t Bonn","doi-asserted-by":"publisher","award":["DRKS00007966"],"award-info":[{"award-number":["DRKS00007966"]}],"id":[{"id":"10.13039\/501100008131","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008131","name":"Rheinische Friedrich-Wilhelms-Universit\u00e4t Bonn","doi-asserted-by":"publisher","award":["04\/05\/2015"],"award-info":[{"award-number":["04\/05\/2015"]}],"id":[{"id":"10.13039\/501100008131","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Prevention of Alzheimer's Disease"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.tjpad.2026.100544","type":"journal-article","created":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T03:51:26Z","timestamp":1774669886000},"page":"100544","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Plasma GFAP outperforms CSF GFAP in detecting amyloid pathology and is associated with increased risk of clinical progression in early Alzheimer\u2019s disease"],"prefix":"10.1016","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-0689-8825","authenticated-orcid":false,"given":"Arda C.","family":"Cetindag","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carola G.","family":"Schipke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5484-9710","authenticated-orcid":false,"given":"Hermann","family":"Esselmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels","family":"Kruse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1492-5330","authenticated-orcid":false,"given":"Jens","family":"Wiltfang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Fliessbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4485-1929","authenticated-orcid":false,"given":"Carolin","family":"Miklitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9335-9594","authenticated-orcid":false,"given":"Franziska","family":"Maier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Buerger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4090-547X","authenticated-orcid":false,"given":"Daniel","family":"Janowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ewers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"St\u00f6cklein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Perneczky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4547-6240","authenticated-orcid":false,"given":"Boris-Stephan","family":"Rauchmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4299-6240","authenticated-orcid":false,"given":"Carolin","family":"Kurz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3586-3194","authenticated-orcid":false,"given":"Stefan","family":"Teipel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo","family":"Kilimann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doreen","family":"Goerss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Laske","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9118-0621","authenticated-orcid":false,"given":"Sebastian","family":"Sodenkamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elham","family":"Najafpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2589-6440","authenticated-orcid":false,"given":"Michael","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8262-4356","authenticated-orcid":false,"given":"Sandra","family":"Roeske","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7244-2014","authenticated-orcid":false,"given":"Ingo","family":"Frommann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3812-023X","authenticated-orcid":false,"given":"Melina","family":"Stark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3137-7516","authenticated-orcid":false,"given":"Frederic","family":"Brosseron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4991-763X","authenticated-orcid":false,"given":"Alfredo","family":"Ramirez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Kleineidam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7596-0979","authenticated-orcid":false,"given":"Josef","family":"Priller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8976-7309","authenticated-orcid":false,"given":"Eike Jakob","family":"Spruth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Gemenetzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Slawek","family":"Altenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emrah","family":"D\u00fczel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5865-4176","authenticated-orcid":false,"given":"Wenzel","family":"Glanz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2014-4098","authenticated-orcid":false,"given":"Enise I.","family":"Incesoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Butryn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Bauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Jessen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0568-2998","authenticated-orcid":false,"given":"Oliver","family":"Peters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tjpad.2026.100544_bib0001","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-4939-7704-8_1","article-title":"Epidemiology of dementia: the burden on society, the challenges for research","volume":"1750","author":"Wolters","year":"2018","journal-title":"Methods Mol Biol"},{"issue":"1","key":"10.1016\/j.tjpad.2026.100544_bib0002","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1056\/NEJMoa2212948","article-title":"Lecanemab in early Alzheimer's Disease","volume":"388","author":"van Dyck","year":"2023","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.tjpad.2026.100544_bib0003","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.jalz.2018.02.018","article-title":"NIA-AA Research Framework: toward a biological definition of Alzheimer's disease","volume":"14","author":"Jr","year":"2018","journal-title":"Alzheimers Dement"},{"issue":"2","key":"10.1016\/j.tjpad.2026.100544_bib0004","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.molmed.2018.11.006","article-title":"Astrocyte biomarkers in Alzheimer's disease","volume":"25","author":"Carter","year":"2019","journal-title":"Trends Mol Med"},{"issue":"3","key":"10.1016\/j.tjpad.2026.100544_bib0005","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/j.ajpath.2011.05.047","article-title":"Reactive glia not only associates with plaques but also parallels tangles in Alzheimer's disease","volume":"179","author":"Serrano-Pozo","year":"2011","journal-title":"Am J Pathol"},{"key":"10.1016\/j.tjpad.2026.100544_bib0006","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/1742-2094-10-90","article-title":"\u00b3H-deprenyl and \u00b3H-PIB autoradiography show different laminar distributions of astroglia and fibrillar \u03b2-amyloid in Alzheimer brain","volume":"10","author":"Marutle","year":"2013","journal-title":"J Neuroinflammation"},{"key":"10.1016\/j.tjpad.2026.100544_bib0007","doi-asserted-by":"crossref","DOI":"10.1038\/srep45496","article-title":"Cortical laminar tau deposits and activated astrocytes in Alzheimer's disease visualised by 3H-THK5117 and 3H-deprenyl autoradiography","volume":"7","author":"Lemoine","year":"2017","journal-title":"Sci Rep."},{"issue":"2","key":"10.1016\/j.tjpad.2026.100544_bib0008","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/jnc.13399","article-title":"Glial fibrillar acidic protein in the cerebrospinal fluid of Alzheimer's disease, dementia with lewy bodies, and frontotemporal lobar degeneration","volume":"136","author":"Ishiki","year":"2016","journal-title":"J Neurochem"},{"issue":"1","key":"10.1016\/j.tjpad.2026.100544_bib0009","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1159\/000050753","article-title":"The cerebrospinal fluid level of glial fibrillary acidic protein is increased in cerebrospinal fluid from Alzheimer's disease patients and correlates with severity of dementia","volume":"46","author":"Fukuyama","year":"2001","journal-title":"Eur Neurol"},{"issue":"3","key":"10.1016\/j.tjpad.2026.100544_bib0010","doi-asserted-by":"crossref","first-page":"541","DOI":"10.3233\/JAD-2009-1075","article-title":"Glial fibrillary acidic protein and protein S-100B: different concentration pattern of glial proteins in cerebrospinal fluid of patients with Alzheimer's disease and Creutzfeldt-Jakob disease","volume":"17","author":"Jesse","year":"2009","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.tjpad.2026.100544_bib0011","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1001\/jamaneurol.2021.3671","article-title":"Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer Disease continuum","volume":"78","author":"Benedet","year":"2021","journal-title":"JAMA Neurol."},{"issue":"3","key":"10.1016\/j.tjpad.2026.100544_bib0012","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.3233\/JAD-200608","article-title":"Serum glial fibrillary acidic protein (GFAP) is a marker of disease severity in frontotemporal lobar degeneration","volume":"77","author":"Benussi","year":"2020","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.tjpad.2026.100544_bib0013","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.neurobiolaging.2021.02.012","article-title":"Astrogliosis and episodic memory in late life: higher GFAP is related to worse memory and white matter microstructure in healthy aging and Alzheimer's disease","volume":"103","author":"Bettcher","year":"2021","journal-title":"Neurobiol Aging"},{"issue":"3","key":"10.1016\/j.tjpad.2026.100544_bib0014","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/alz.12745","article-title":"Amyloid-beta misfolding and GFAP predict risk of clinical Alzheimer's disease diagnosis within 17 years","volume":"19","author":"Beyer","year":"2023","journal-title":"Alzheimers Dement"},{"issue":"6","key":"10.1016\/j.tjpad.2026.100544_bib0015","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1136\/jnnp-2021-327788","article-title":"Differential levels of plasma biomarkers of neurodegeneration in lewy body dementia, Alzheimer's disease, frontotemporal dementia and progressive supranuclear palsy","volume":"93","author":"Chouliaras","year":"2022","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"1","key":"10.1016\/j.tjpad.2026.100544_bib0016","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s13195-021-00804-9","article-title":"Plasma glial fibrillary acidic protein detects Alzheimer pathology and predicts future conversion to Alzheimer dementia in patients with mild cognitive impairment","volume":"13","author":"Cicognola","year":"2021","journal-title":"Alzheimers Res Ther"},{"issue":"13","key":"10.1016\/j.tjpad.2026.100544_bib0017","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.0000000000200035","article-title":"Association of CSF, plasma, and imaging markers of neurodegeneration with clinical progression in people with subjective cognitive decline","volume":"98","author":"Ebenau","year":"2022","journal-title":"Neurology"},{"issue":"7","key":"10.1016\/j.tjpad.2026.100544_bib0018","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1002\/alz.12283","article-title":"The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease","volume":"17","author":"Simr\u00e9n","year":"2021","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.tjpad.2026.100544_bib0019","doi-asserted-by":"crossref","DOI":"10.1093\/braincomms\/fcab008","article-title":"Detection of \u03b2-amyloid posi- tivity in Alzheimer\u2019s Disease Neuroimaging Initiative participants with demographics, cognition. MRI and plasma biomarkers","volume":"3","author":"Tosun","year":"2021","journal-title":"Brain Commun"},{"key":"10.1016\/j.tjpad.2026.100544_bib0020","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1002\/alz.12447","article-title":"Diagnostic and prog- nostic plasma biomarkers for preclinical Alzheimer\u2019s disease","volume":"18","author":"Chatterjee","year":"2022","journal-title":"Alzhei- mer\u2019s & Dementia"},{"key":"10.1016\/j.tjpad.2026.100544_bib0021","doi-asserted-by":"crossref","first-page":"4270","DOI":"10.1007\/s00415-022-11055-5","article-title":"Plasma neurofil- ament light chain as a biomarker of Alzheimer\u2019s disease in Subjec- tive cognitive decline and mild cognitive impairment","volume":"269","author":"Giacomucci","year":"2022","journal-title":"J Neurol"},{"issue":"3","key":"10.1016\/j.tjpad.2026.100544_bib0022","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s10072-023-07065-4","article-title":"The role of plasma neurofilament light chain and glial fibrillary acidic protein in subjective cognitive decline and mild cognitive impairment","volume":"45","author":"Mazzeo","year":"2024","journal-title":"Neurol Sci"},{"key":"10.1016\/j.tjpad.2026.100544_bib0023","doi-asserted-by":"crossref","DOI":"10.1186\/s13195-022-01093-6","article-title":"Diagnostic value of plasma p-tau181, NfL, and GFAP in a clinical setting cohort of prevalent neurodegenerative dementias","volume":"14","author":"Baiardi","year":"2022","journal-title":"Alzheimers Res. Ther."},{"issue":"1","key":"10.1016\/j.tjpad.2026.100544_bib0024","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s13195-017-0314-2","article-title":"Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE)","volume":"10","author":"Jessen","year":"2018","journal-title":"Alzheimers Res Ther"},{"issue":"2","key":"10.1016\/j.tjpad.2026.100544_bib0025","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1002\/alz.12674","article-title":"Subjective cognitive decline and stage 2 of Alzheimer disease in patients from memory centers","volume":"19","author":"Jessen","year":"2023","journal-title":"Alzheimers Dement"},{"issue":"6","key":"10.1016\/j.tjpad.2026.100544_bib0026","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.jalz.2014.01.001","article-title":"Subjective Cognitive Decline Initiative (SCD-I) Working Group. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease","volume":"10","author":"Jessen","year":"2014","journal-title":"Alzheimers Dement"},{"issue":"3","key":"10.1016\/j.tjpad.2026.100544_bib0027","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.jalz.2016.09.012","article-title":"Subjective Cognitive Decline Initiative (SCD-I) Working Group. Implementation of subjective cognitive decline criteria in research studies","volume":"13","author":"Molinuevo","year":"2017","journal-title":"Alzheimers Dement"},{"issue":"3","key":"10.1016\/j.tjpad.2026.100544_bib0028","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.jalz.2011.03.008","article-title":"The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease","volume":"7","author":"Albert","year":"2011","journal-title":"Alzheimers Dement."},{"issue":"3","key":"10.1016\/j.tjpad.2026.100544_bib0029","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jalz.2011.03.005","article-title":"The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease","volume":"7","author":"McKhann","year":"2011","journal-title":"Alzheimers Dement."},{"issue":"6","key":"10.1016\/j.tjpad.2026.100544_bib0030","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1002\/alz.12896","article-title":"Amyloid futures in the expanding pathology of brain aging and dementia","volume":"19","author":"Thorwald","year":"2023","journal-title":"Alzheimers Dement"},{"issue":"9","key":"10.1016\/j.tjpad.2026.100544_bib0031","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.3390\/cells12091309","article-title":"GFAP as a potential biomarker for Alzheimer's Disease: A systematic review and meta-analysis","volume":"12","author":"Kim","year":"2023","journal-title":"Cells."},{"key":"10.1016\/j.tjpad.2026.100544_bib0032","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1375302","article-title":"Plasma GFAP, NfL and pTau 181 detect preclinical stages of dementia","volume":"15","author":"Ingannato","year":"2024","journal-title":"Front Endocrinol (Lausanne)."},{"issue":"1","key":"10.1016\/j.tjpad.2026.100544_bib0033","article-title":"Plasma biomarker trajectories: impact of AD genetic risk and clinical progression","volume":"17","author":"Pettigrew","year":"2025","journal-title":"Alzheimers Dement (Amst)"},{"key":"10.1016\/j.tjpad.2026.100544_bib0034","doi-asserted-by":"crossref","DOI":"10.1038\/s41591-025-03605-x","article-title":"Blood-based biomarkers of Alzheimer's disease and incident dementia in the community","author":"Grande","year":"2025","journal-title":"Nat Med"},{"key":"10.1016\/j.tjpad.2026.100544_bib0035","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.pneurobio.2016.01.001","article-title":"Astrogliosis: an integral player in the pathogenesis of Alzheimer's disease","volume":"144","author":"Osborn","year":"2016","journal-title":"Prog Neurobiol"},{"issue":"1","key":"10.1016\/j.tjpad.2026.100544_bib0036","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2967\/jnumed.110.087031","article-title":"Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG","volume":"53","author":"Carter","year":"2012","journal-title":"J Nucl Med"},{"issue":"Pt 3","key":"10.1016\/j.tjpad.2026.100544_bib0037","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1093\/brain\/awv404","article-title":"Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer's disease","volume":"139","author":"Rodriguez-Vieitez","year":"2016","journal-title":"Brain."},{"issue":"1","key":"10.1016\/j.tjpad.2026.100544_bib0038","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/s13195-020-00682-7","article-title":"Combination of plasma amyloid beta(1-42\/1-40) and glial fibrillary acidic protein strongly associates with cerebral amyloid pathology","volume":"12","author":"Verberk","year":"2020","journal-title":"Alzheimers Res Ther"},{"issue":"6","key":"10.1016\/j.tjpad.2026.100544_bib0039","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1016\/j.ajpath.2013.02.031","article-title":"A phenotypic change but not proliferation underlies glial responses in Alzheimer disease","volume":"182","author":"Serrano-Pozo","year":"2013","journal-title":"Am J Pathol"},{"issue":"4","key":"10.1016\/j.tjpad.2026.100544_bib0040","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/S1474-4422(15)70016-5","article-title":"Neuroinflammation in Alzheimer's disease","volume":"14","author":"Heneka","year":"2015","journal-title":"Lancet Neurol"},{"issue":"8","key":"10.1016\/j.tjpad.2026.100544_bib0041","doi-asserted-by":"crossref","first-page":"5132","DOI":"10.1002\/alz.13909","article-title":"Plasma amyloid beta X-42\/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease","volume":"20","author":"Vogelgsang","year":"2024","journal-title":"Alzheimers Dement"},{"issue":"3","key":"10.1016\/j.tjpad.2026.100544_bib0042","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1001\/jamaneurol.2023.5319","article-title":"Diagnostic accuracy of a plasma phosphorylated tau 217 immunoassay for Alzheimer Disease pathology","volume":"81","author":"Ashton","year":"2024","journal-title":"JAMA Neurol"}],"container-title":["The Journal of Prevention of Alzheimer's Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2274580726000683?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2274580726000683?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T02:57:34Z","timestamp":1792724254000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2274580726000683"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":42,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S2274580726000683"],"URL":"https:\/\/doi.org\/10.1016\/j.tjpad.2026.100544","relation":{},"ISSN":["2274-5807"],"issn-type":[{"value":"2274-5807","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Plasma GFAP outperforms CSF GFAP in detecting amyloid pathology and is associated with increased risk of clinical progression in early Alzheimer\u2019s disease","name":"articletitle","label":"Article Title"},{"value":"The Journal of Prevention of Alzheimer's Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tjpad.2026.100544","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Masson SAS on behalf of SERDI Publisher.","name":"copyright","label":"Copyright"}],"article-number":"100544"}}