{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T23:35:48Z","timestamp":1780616148557,"version":"3.54.1"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Travel Medicine and Infectious Disease"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.tmaid.2021.102117","type":"journal-article","created":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T11:37:54Z","timestamp":1623497874000},"page":"102117","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Ototoxic hearing loss from antimalarials: A systematic narrative review"],"prefix":"10.1016","volume":"43","author":[{"given":"Lauren K.","family":"Dillard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2312-8026","authenticated-orcid":false,"given":"Amanda M.","family":"Fullerton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine M.","family":"McMahon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tmaid.2021.102117_bib1","series-title":"World malaria report 2019","author":"World Health Organization","year":"2020"},{"key":"10.1016\/j.tmaid.2021.102117_bib2","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1016\/S0140-6736(07)60602-3","article-title":"Global burden of childhood hearing impairment and disease control priorities for developing countries","volume":"369","author":"Olusanya","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.tmaid.2021.102117_bib3","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1097\/AUD.0b013e31803126b6","article-title":"Hearing impairment and health-related quality of life: The Blue Mountains hearing study","volume":"28","author":"Chia","year":"2007","journal-title":"Ear Hear"},{"issue":"Suppl_2","key":"10.1016\/j.tmaid.2021.102117_bib4","doi-asserted-by":"crossref","first-page":"S256","DOI":"10.1093\/geront\/gnw033","article-title":"Aging and hearing health: The life-course approach","volume":"56","author":"Davis","year":"2016","journal-title":"Gerontologist"},{"key":"10.1016\/j.tmaid.2021.102117_bib5","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.1016\/S0140-6736(17)31363-6","article-title":"Dementia prevention, intervention, and care","volume":"390","author":"Livingston","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.tmaid.2021.102117_bib6","author":"United Nations"},{"key":"10.1016\/j.tmaid.2021.102117_bib7","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.apmr.2019.08.468","article-title":"Rehabilitation is a global health priority","volume":"101","author":"Heinemann","year":"2020","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.tmaid.2021.102117_bib8","series-title":"WHO model lists of essential medicines","author":"World Health Organization","year":"2019"},{"key":"10.1016\/j.tmaid.2021.102117_bib9","doi-asserted-by":"crossref","first-page":"140","DOI":"10.3181\/00379727-20-69","article-title":"On the effect of certain drugs, notably quinine, on the acuity of hearing","volume":"20","author":"Pohlman","year":"1922","journal-title":"Exp Biol Med"},{"key":"10.1016\/j.tmaid.2021.102117_bib10","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1001\/archotol.1959.00730040329006","article-title":"Ototoxicity of quinine in experimental animals","volume":"70","author":"Hennebert","year":"1959","journal-title":"Arch Otolaryngol"},{"key":"10.1016\/j.tmaid.2021.102117_bib11","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/bcpt.12640","article-title":"Concentration\u2013response relationship of hearing impairment caused by quinine and salicylate: pharmacological similarities but different molecular mechanisms","volume":"120","author":"Alvan","year":"2017","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"10.1016\/j.tmaid.2021.102117_bib12","doi-asserted-by":"crossref","first-page":"76","DOI":"10.3109\/03005368209081451","article-title":"Some historical aspects of ototoxicity","volume":"16","author":"Stephens","year":"1982","journal-title":"Br J Audiol"},{"key":"10.1016\/j.tmaid.2021.102117_bib13","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3109\/03005368209081452","article-title":"The pharmacology of ototoxic drugs","volume":"16","author":"Harpur","year":"1982","journal-title":"Br J Audiol"},{"key":"10.1016\/j.tmaid.2021.102117_bib14","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1001\/jama.1946.02870160015006","article-title":"Activity of a new antimalarial agent","volume":"130","author":"Loeb","year":"1946","journal-title":"chloroquine (SN 7618). JAMA"},{"key":"10.1016\/j.tmaid.2021.102117_bib15","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1007\/s10067-007-0662-6","article-title":"Chloroquine ototoxicity","volume":"26","author":"Bortoli","year":"2007","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.tmaid.2021.102117_bib16","article-title":"Chloroquine and hydroxychloroquine ototoxicity; potential implications for SARS-CoV-2 treatment. A brief review of the literature","author":"De Luca","year":"2020","journal-title":"Am J Otolaryngol"},{"key":"10.1016\/j.tmaid.2021.102117_bib17","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1126\/science.1105787","article-title":"Mefloquine (WR 142,490) in the treatment of human malaria","volume":"190","author":"Trenholme","year":"1975","journal-title":"Science"},{"key":"10.1016\/j.tmaid.2021.102117_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12936-016-1391-6","article-title":"Psychiatric effects of malaria and anti-malarial drugs: historical and modern perspectives","volume":"15","author":"Nevin","year":"2016","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2021.102117_bib19","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1038\/nrmicro2239","article-title":"Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria","volume":"7","author":"Eastman","year":"2009","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.tmaid.2021.102117_bib20","series-title":"Novartis. Novartis malaria initiative","year":"2007"},{"key":"10.1016\/j.tmaid.2021.102117_bib21","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0035-9203(94)90469-3","article-title":"Neurotoxicity in animals due to arteether and artemether","volume":"88","author":"Brewer","year":"1994","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"10.1016\/j.tmaid.2021.102117_bib22","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0361-9230(97)00339-0","article-title":"Dose-dependent brainstem neuropathology following repeated arteether administration in rats","volume":"45","author":"Genovese","year":"1998","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.tmaid.2021.102117_bib23","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/s004290050326","article-title":"Arteether-induced brain injury in Macaca mulatta. I. The precerebellar nuclei: the lateral reticular nuclei, paramedian reticular nuclei, and perihypoglossal nuclei","volume":"201","author":"Petras","year":"2000","journal-title":"Anat Embryol"},{"key":"10.1016\/j.tmaid.2021.102117_bib24","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3109\/10408441003610571","article-title":"Toxicity of the antimalarial artemisinin and its dervatives","volume":"40","author":"Efferth","year":"2010","journal-title":"Crit Rev Toxicol"},{"key":"10.1016\/j.tmaid.2021.102117_bib25","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.neuro.2011.03.003","article-title":"Neurological assessments after treatment with the antimalarial \u03b2-arteether in neonatal and adult rats","volume":"32","author":"Erickson","year":"2011","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.tmaid.2021.102117_bib26","doi-asserted-by":"crossref","first-page":"62","DOI":"10.4269\/ajtmh.13-0702","article-title":"Neuroauditory toxicity of artemisinin combination therapies\u2014have safety concerns been addressed?","volume":"91","author":"Ramos-Mart\u00edn","year":"2014","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.tmaid.2021.102117_bib27","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.ijsu.2010.02.007","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"8","author":"Moher","year":"2010","journal-title":"Int J Surg"},{"key":"10.1016\/j.tmaid.2021.102117_bib28","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1016\/S0140-6736(08)61492-0","article-title":"Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: a randomised, single-blind, multicentre trial","volume":"372","author":"Abdulla","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.tmaid.2021.102117_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/360540","article-title":"Reversible audiometric threshold changes in children with uncomplicated malaria","volume":"2013","author":"Adjei","year":"2013","journal-title":"J Trop Med"},{"key":"10.1016\/j.tmaid.2021.102117_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2875-7-127","article-title":"Amodiaquine-artesunate vs artemether-lumefantrine for uncomplicated malaria in Ghanaian children: a randomized efficacy and safety trial with one year follow-up","volume":"7","author":"Adjei","year":"2008","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2021.102117_bib31","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s10096-007-0264-x","article-title":"Selective ambulatory management of imported falciparum malaria: a 5-year prospective study","volume":"26","author":"Bottieau","year":"2007","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.tmaid.2021.102117_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2875-11-212","article-title":"Therapy of uncomplicated falciparum malaria in Europe: MALTHER\u2013a prospective observational multicentre study","volume":"11","author":"Bouchaud","year":"2012","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2021.102117_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2875-7-233","article-title":"Auditory assessment of patients with acute uncomplicated Plasmodium falciparum malaria treated with three-day mefloquine-artesunate on the north-western border of Thailand","volume":"7","author":"Carrara","year":"2008","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2021.102117_bib34","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4269\/ajtmh.2012.11-0192","article-title":"Randomized, prospective, three-arm study to confirm the auditory safety and efficacy of artemether-lumefantrine in Colombian patients with uncomplicated Plasmodium falciparum malaria","volume":"86","author":"Carrasquilla","year":"2012","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.tmaid.2021.102117_bib35","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/tropej\/fmh069","article-title":"A randomized open label clinical trial to compare the efficacy and safety of intravenous quinine followed by oral malarone vs. intravenous quinine followed by oral quinine in the treatment of severe malaria","volume":"51","author":"Esamai","year":"2005","journal-title":"J Trop Pediatr"},{"key":"10.1016\/j.tmaid.2021.102117_bib36","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.ijporl.2010.02.010","article-title":"Sensorineural deafness in Tanzanian children\u2014is ototoxicity a significant cause? A pilot study","volume":"74","author":"Freeland","year":"2010","journal-title":"Int J Pediatr Otolarngol"},{"key":"10.1016\/j.tmaid.2021.102117_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2875-8-196","article-title":"Artemisinin-naphthoquine combination (ARCO\u2122) therapy for uncomplicated falciparum malaria in adults of Papua New Guinea: a preliminary report on safety and efficacy","volume":"8","author":"Hombhanje","year":"2009","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2021.102117_bib38","doi-asserted-by":"crossref","first-page":"211","DOI":"10.4269\/ajtmh.2006.74.211","article-title":"A case-control auditory evaluation of patients treated with artemether-lumefantrine","volume":"74","author":"Hutagalung","year":"2006","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.tmaid.2021.102117_bib39","first-page":"86","article-title":"Efficacy of loading versus standard doses of quinine in cerebral malaria","volume":"36","author":"Khan","year":"2011","journal-title":"RMJ"},{"key":"10.1016\/j.tmaid.2021.102117_bib40","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/1475-2875-11-102","article-title":"Treatment outcome of intravenous artesunate in patients with severe malaria in The Netherlands and Belgium","volume":"11","author":"Kreeftmeijer-Vegter","year":"2012","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2021.102117_bib41","doi-asserted-by":"crossref","first-page":"3884","DOI":"10.1128\/AAC.00039-16","article-title":"Efficacy and safety of pyronaridine-artesunate for treatment of uncomplicated Plasmodium falciparum malaria in western Cambodia","volume":"60","author":"Leang","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"10.1016\/j.tmaid.2021.102117_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2875-11-184","article-title":"Efficacy of artemether-lumefantrine, the nationally-recommended artemisinin combination for the treatment of uncomplicated falciparum malaria, in southern Laos","volume":"11","author":"Mayxay","year":"2012","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2021.102117_bib43","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.trstmh.2006.02.017","article-title":"No hearing loss associated with the use of artemether\u2013lumefantrine to treat experimental human malaria","volume":"100","author":"McCall","year":"2006","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"10.1016\/j.tmaid.2021.102117_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2875-11-413","article-title":"Open-label trial of three dosage regimens of fixed-dose combination of artemisinin and naphthoquine for treating uncomplicated falciparum malaria in Calabar, Nigeria","volume":"11","author":"Meremikwu","year":"2012","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2021.102117_bib45","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s40261-016-0385-z","article-title":"Safety profile of artemether-lumefantrine: a cohort event monitoring study in public health facilities in Tanzania","volume":"36","author":"Mssusa","year":"2016","journal-title":"Clin Drug Invest"},{"key":"10.1016\/j.tmaid.2021.102117_bib46","doi-asserted-by":"crossref","first-page":"453","DOI":"10.4103\/1119-3077.104527","article-title":"Prevalence of ototoxicity in University of Benin Teaching Hospital, Benin city: a 5. year review","volume":"15","author":"Obasikene","year":"2012","journal-title":"Niger J Clin Pract"},{"key":"10.1016\/j.tmaid.2021.102117_bib47","doi-asserted-by":"crossref","first-page":"600","DOI":"10.3855\/jidc.2769","article-title":"Clinical and laboratory predictors of outcome in cerebral malaria in suburban Nigeria","volume":"7","author":"Oluwayemi","year":"2013","journal-title":"J Infect Dev Ctries"},{"key":"10.1016\/j.tmaid.2021.102117_bib48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12916-015-0366-8","article-title":"Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions-a prospective multicenter cohort study","volume":"13","author":"Schmutzhard","year":"2015","journal-title":"BMC Med"},{"key":"10.1016\/j.tmaid.2021.102117_bib49","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.tmaid.2005.02.003","article-title":"Effects of weight, age, and time on artemether\u2013lumefantrine associated ototoxicity and evidence of irreversibility","volume":"4","author":"Toovey","year":"2006","journal-title":"Trav Med Infect Dis"},{"key":"10.1016\/j.tmaid.2021.102117_bib50","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1288\/00005537-195204000-00001","article-title":"Further observations concerning the toxic effects of streptomycin and quinine on the auditory organ of Guinea pigs","volume":"62","author":"Ruedi","year":"1952","journal-title":"Laryngoscope"},{"key":"10.1016\/j.tmaid.2021.102117_bib51","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/0304-3940(90)90393-N","article-title":"Quinine causes isolated outer hair cells to change length","volume":"116","author":"Karlsson","year":"1990","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.tmaid.2021.102117_bib52","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0378-5955(01)00229-5","article-title":"Quinine-induced alterations of electrically evoked otoacoustic emissions and cochlear potentials in Guinea pigs","volume":"154","author":"Zheng","year":"2001","journal-title":"Hear Res"},{"key":"10.1016\/j.tmaid.2021.102117_bib53","first-page":"76","article-title":"Ototoxic effects of mefloquine in cochlear organotypic cultures","volume":"4","author":"Ding","year":"2009","journal-title":"J Otolaryngol"},{"key":"10.1016\/j.tmaid.2021.102117_bib54","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.tmaid.2008.12.004","article-title":"Mefloquine neurotoxicity: a literature review","volume":"7","author":"Toovey","year":"2009","journal-title":"Trav Med Infect Dis"},{"key":"10.1016\/j.tmaid.2021.102117_bib55","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0091-3057(98)00019-7","article-title":"Behavioral and neural toxicity of arteether in rats","volume":"60","author":"Genovese","year":"1998","journal-title":"Pharmacol Biol Behav"},{"key":"10.1016\/j.tmaid.2021.102117_bib56","doi-asserted-by":"crossref","first-page":"423","DOI":"10.4269\/ajtmh.2002.67.423","article-title":"Neuropathologic toxicity of artemisinin derivatives in a mouse model","volume":"67","author":"Nontprasert","year":"2002","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.tmaid.2021.102117_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1179\/146532811X12925735813724","article-title":"Deafness: malaria as a forgotten cause","volume":"31","author":"Zhao","year":"2011","journal-title":"Ann Trop Paediatr"},{"key":"10.1016\/j.tmaid.2021.102117_bib58","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0165-5876(85)80024-0","article-title":"A study of deafness in West Africa: the Gambian hearing health project","volume":"10","author":"McPherson","year":"1985","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.tmaid.2021.102117_bib59","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/S1474-4422(05)70247-7","article-title":"Pathogenesis, clinical features, and neurological outcome of cerebral malaria","volume":"4","author":"Idro","year":"2005","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.tmaid.2021.102117_bib60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12936-019-2840-9","article-title":"A long-term follow-up study on otoacoustic emissions testing in paediatric patients with severe malaria in Gabon","volume":"18","author":"Reiterer","year":"2019","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2021.102117_bib61","article-title":"Prevalence of aminoglycoside-induced hearing loss in drug-resistant tuberculosis patients: A systematic review","volume":"5122","author":"Dillard","year":"2021","journal-title":"J Infect"}],"container-title":["Travel Medicine and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1477893921001587?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1477893921001587?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:07:04Z","timestamp":1761487624000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1477893921001587"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":61,"alternative-id":["S1477893921001587"],"URL":"https:\/\/doi.org\/10.1016\/j.tmaid.2021.102117","relation":{},"ISSN":["1477-8939"],"issn-type":[{"value":"1477-8939","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ototoxic hearing loss from antimalarials: A systematic narrative review","name":"articletitle","label":"Article Title"},{"value":"Travel Medicine and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tmaid.2021.102117","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102117"}}