{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T19:08:35Z","timestamp":1763665715955,"version":"build-2065373602"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T00:00:00Z","timestamp":1742947200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Travel Medicine and Infectious Disease"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.tmaid.2025.102846","type":"journal-article","created":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T06:04:35Z","timestamp":1743141875000},"page":"102846","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Screening for Chagas disease in Latin-American pregnant women and their newborns: A prospective observational, multicenter study in Milan, Italy"],"prefix":"10.1016","volume":"65","author":[{"given":"Federico","family":"Sabaini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Giacomelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatrice","family":"Tassis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariagrazia","family":"Ierardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Maria","family":"Marconi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Ronchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Cetin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lea","family":"Testa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Savasi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Fabbri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Alabiso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greta","family":"Nova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Vignali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikita","family":"Alfieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vania","family":"Giacomet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Beltrami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Casalini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margherita","family":"Longo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Grosso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romualdo","family":"Grande","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0569-9407","authenticated-orcid":false,"given":"Spinello","family":"Antinori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10422","key":"10.1016\/j.tmaid.2025.102846_bib1","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0140-6736(23)01787-7","article-title":"Chagas disease","volume":"403","author":"De Sousa","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.tmaid.2025.102846_bib2","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.ejim.2017.05.001","article-title":"Chagas disease in Europe: a review for the internist in the globalized world","volume":"43","author":"Antinori","year":"2017","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.tmaid.2025.102846_bib3","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.actatropica.2016.01.002","article-title":"A global systematic review of Chagas disease prevalence among migrants","volume":"156","author":"Conners","year":"2016","journal-title":"Acta Trop"},{"issue":"1","key":"10.1016\/j.tmaid.2025.102846_bib4","doi-asserted-by":"crossref","DOI":"10.1093\/jtm\/taaa170","article-title":"Trypanosoma cruzi infection in Latin American pregnant women living outside endemic countries and frequency of congenital transmission: a systematic review and meta-analysis","volume":"28","author":"Colombo","year":"2021","journal-title":"J Travel Med"},{"issue":"4","key":"10.1016\/j.tmaid.2025.102846_bib5","doi-asserted-by":"crossref","first-page":"e439","DOI":"10.1016\/S2214-109X(17)30073-6","article-title":"Cost-effectiveness of Chagas disease screening in Latin American migrants at primary health-care centres in Europe: a Markov model analysis","volume":"5","author":"Requena-M\u00e9ndez","year":"2017","journal-title":"Lancet Global Health"},{"issue":"11","key":"10.1016\/j.tmaid.2025.102846_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006809","article-title":"The economic value of identifying and treating Chagas disease patients earlier and the impact on Trypanosoma cruzi transmission","volume":"12","author":"Bartsch","year":"2018","journal-title":"PLos Negl Trop Dis"},{"issue":"2","key":"10.1016\/j.tmaid.2025.102846_bib7","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.actatropica.2011.02.012","article-title":"Economic evaluation of Chagas disease screening of pregnant Latin American women and of their infants in a non-endemic area","volume":"118","author":"Sicuri","year":"2011","journal-title":"Acta Trop"},{"issue":"1","key":"10.1016\/j.tmaid.2025.102846_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0011895","article-title":"Efficacy of short-course treatment for prevention of congenital transmission of Chagas disease: a retrospective cohort study","volume":"18","author":"Moscatelli","year":"2024","journal-title":"PLos Negl Trop Dis"},{"key":"10.1016\/j.tmaid.2025.102846_bib9","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1093\/infdis\/jix087","article-title":"Treatment of infected women of childbearing age prevents congenital Trypanosoma cruzi infection by eliminating the parasitemia detected by PCR","volume":"215","author":"Murcia","year":"2017","journal-title":"J Infect Dis"},{"key":"10.1016\/j.tmaid.2025.102846_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0008912","article-title":"Prospective historically controlled study to evaluate the efficacy and safety of a new pediatric formulation of nifurtimox in children aged 0 to 17 years with Chagas disease one year after treatment (CHICO)","volume":"15","author":"Altcheh","year":"2021","journal-title":"PLos Negl Trop Dis"},{"key":"10.1016\/j.tmaid.2025.102846_bib11","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1007\/s11739-020-02387-z","article-title":"Chagas disease in Italy: updated estimates","volume":"15","author":"Campolmi","year":"2020","journal-title":"Intern Emerg Med"},{"issue":"1","key":"10.1016\/j.tmaid.2025.102846_bib12","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1186\/s12879-018-3118-5","article-title":"Serological evaluation for Chagas disease in migrants from Latin American countries in Rome, Italy","volume":"18","author":"Pane","year":"2018","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.tmaid.2025.102846_bib13","doi-asserted-by":"crossref","first-page":"1340e1","DOI":"10.1016\/j.cmi.2018.03.017","article-title":"Chagas disease knocks on our door: a cross-sectional study among Latin American immigrants in Milan, Italy","volume":"24","author":"Antinori","year":"2018","journal-title":"Clin Microbiol Infect"},{"issue":"1","key":"10.1016\/j.tmaid.2025.102846_bib14","doi-asserted-by":"crossref","DOI":"10.1093\/jtm\/taaa201","article-title":"Ongoing mother-to-child transmission of Chagas disease in Italy: 2014-2018 estimates","volume":"28","author":"Zammarchi","year":"2021","journal-title":"J Travel Med"},{"key":"10.1016\/j.tmaid.2025.102846_bib15","article-title":"Family cluster of Chagas disease among Bolivian immigrants in Italy: high rate of maternal-fetal transmission","volume":"43","author":"Antinori","year":"2022","journal-title":"Trav Med Infect Dis"},{"issue":"1","key":"10.1016\/j.tmaid.2025.102846_bib16","first-page":"93","article-title":"Congenital chagas disease in a Bolivian newborn in Bergamo, Italy","volume":"26","author":"Bargiggia","year":"2018","journal-title":"Infez Med"},{"issue":"5","key":"10.1016\/j.tmaid.2025.102846_bib17","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2018-001069","article-title":"The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America","volume":"3","author":"Picado","year":"2018","journal-title":"BMJ Glob Health"},{"key":"10.1016\/j.tmaid.2025.102846_bib18","unstructured":"Istituto Superiore di Sanit\u00e0. Aggiornate le linee guida sulla gravidanza fisiologica: nuove raccomandazioni su informazioni e screening per le malattie infettive (aggiornate al 30\/01\/2024). https:\/\/www.iss.it\/it\/web\/guest\/-\/gravidanza-fisiologica."},{"issue":"3","key":"10.1016\/j.tmaid.2025.102846_bib19","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1002\/ijgo.15812","article-title":"Screening of Chagas disease in pregnant women-recommendation by the Italian National Institute of Health, 2023","volume":"167","author":"Ornaghi","year":"2024","journal-title":"Int J Gynaecol Obstet"},{"issue":"9","key":"10.1016\/j.tmaid.2025.102846_bib20","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.cmi.2016.06.001","article-title":"Serodiscordance in chronic Chagas disease diagnosis: a real problem in non-endemic countries","volume":"22","author":"Moure","year":"2016","journal-title":"Clin Microbiol Infect"},{"issue":"26","key":"10.1016\/j.tmaid.2025.102846_bib21","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2019.24.26.19-00011","article-title":"Epidemiology of congenital Chagas disease 6 years after implementation of a public health surveillance system, Catalonia, 2010 to 2015","volume":"24","author":"Basile","year":"2019","journal-title":"Euro Surveill"},{"key":"10.1016\/j.tmaid.2025.102846_bib22","first-page":"1","article-title":"Prevalence of Chagas disease in Latin American pregnant women in Madrid, Spain: a multicentre cross-sectional study from 2011 to 2016","author":"Herrero-Martinez","year":"2023","journal-title":"Trop Med Int Health"},{"key":"10.1016\/j.tmaid.2025.102846_bib23","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.tmaid.2018.04.011","article-title":"Congenital Chagas disease in a non-endemic area: results from a control programme in Bergamo province, Northern Italy","volume":"25","author":"Rodari","year":"2018","journal-title":"Travel Med Infect Dis"},{"issue":"2","key":"10.1016\/j.tmaid.2025.102846_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003540","article-title":"Prevalence of Chagas disease in Latin American migrants living in Europe: a systematic review and meta-analysis","volume":"9","author":"Requena-M\u00e9ndez","year":"2015","journal-title":"PLos Negl Trop Dis"},{"issue":"12","key":"10.1016\/j.tmaid.2025.102846_bib25","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.49120","article-title":"Targeted maternal chagas disease screening among individuals born in a chagas-endemic country","volume":"7","author":"Proa\u00f1o","year":"2024","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.tmaid.2025.102846_bib26","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1007\/s00404-011-2081-9","article-title":"Chagas disease in Latin American pregnant immigrants: experience in a non-endemic country","volume":"285","author":"Ramos","year":"2021","journal-title":"Arch Gynecol Obstet"},{"issue":"3","key":"10.1016\/j.tmaid.2025.102846_bib27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0009281","article-title":"Chagas disease screening in pregnant Latin American women: adherence to a systematic screening protocol in a non-endemic country","volume":"15","author":"Llenas-Garcia","year":"2020","journal-title":"PLos Negl Trop Dis"},{"key":"10.1016\/j.tmaid.2025.102846_bib28","series-title":"Periodo 2010-2022","article-title":"Informe sobre el Programa de prevenci\u00f2n i control de la Enfermedad de Chagas congenita en Catalu\u0148a","author":"Ciruela","year":"2024"},{"key":"10.1016\/j.tmaid.2025.102846_bib29","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1080\/23744235.2023.2222817","article-title":"Chagas disease prevalence among migrants from El Salvador in Milan: a cross-sectional study of an often-overlooked population","volume":"55","author":"Beltrami","year":"2023","journal-title":"Infect Dis (London)"},{"issue":"2","key":"10.1016\/j.tmaid.2025.102846_bib30","first-page":"243","article-title":"Prevention of congenital Chagas disease by screening mothers and monitoring of serological tests of neonates: the seven years' experience","volume":"31","author":"Raglio","year":"2023","journal-title":"Infez Med"},{"issue":"1","key":"10.1016\/j.tmaid.2025.102846_bib31","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3390\/microorganisms11010154","article-title":"A questionnaire integrated with the digital medical record improved the coverage of a control program for congenital chagas disease in tuscany, Italy","volume":"11","author":"Barbiero","year":"2023","journal-title":"Microorganisms"},{"issue":"9","key":"10.1016\/j.tmaid.2025.102846_bib32","article-title":"Prevention of congenital chagas disease by trypanocide treatment in women of reproductive age: a meta-analysis of observational studies","volume":"18","author":"Aquino de Moraes","year":"2024","journal-title":"PLos Negl Trop Dis"}],"container-title":["Travel Medicine and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1477893925000523?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1477893925000523?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T20:35:32Z","timestamp":1762547732000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1477893925000523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":32,"alternative-id":["S1477893925000523"],"URL":"https:\/\/doi.org\/10.1016\/j.tmaid.2025.102846","relation":{},"ISSN":["1477-8939"],"issn-type":[{"type":"print","value":"1477-8939"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Screening for Chagas disease in Latin-American pregnant women and their newborns: A prospective observational, multicenter study in Milan, Italy","name":"articletitle","label":"Article Title"},{"value":"Travel Medicine and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tmaid.2025.102846","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102846"}}