{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:41:04Z","timestamp":1792726864773,"version":"4.5.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Travel Medicine and Infectious Disease"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.tmaid.2026.103031","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T15:02:44Z","timestamp":1792162964000},"page":"103031","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Management of uncomplicated Plasmodium falciparum malaria with artemisinin-based combination therapy: Factors associated with hospitalization and clinical, biological, and parasitological outcomes"],"prefix":"10.1016","volume":"74","author":[{"given":"Sally Oceane","family":"Minka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Wumba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Souad","family":"Bani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Pradines","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marylin","family":"Madamet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8794-8923","authenticated-orcid":false,"given":"Oc\u00e9ane","family":"Delandre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3760-3537","authenticated-orcid":false,"given":"Emilie","family":"Javelle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9875-7973","authenticated-orcid":false,"given":"Fadi Hillary","family":"Minka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4867-2423","authenticated-orcid":false,"given":"Marc","family":"Thellier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine","family":"Houze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tmaid.2026.103031_bib1","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1016\/S0140-6736(23)01249-7","article-title":"Malaria","volume":"402","author":"Poespoprodjo","year":"2023","journal-title":"Lancet"},{"key":"10.1016\/j.tmaid.2026.103031_bib2","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1016\/j.cmi.2024.06.021","article-title":"How to manage adult patients with malaria in the non-endemic setting","volume":"30","author":"Antinori","year":"2024","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.tmaid.2026.103031_bib3","series-title":"World malaria report","year":"2025"},{"key":"10.1016\/j.tmaid.2026.103031_bib4","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.idnow.2021.08.002","article-title":"Imported malaria in metropolitan France, from recommendations to clinical practice \u2013 proposal for improvement","volume":"51","author":"Dupr\u00e9","year":"2021","journal-title":"Infect Dis Now"},{"key":"10.1016\/j.tmaid.2026.103031_bib5","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2020.25.36.1900579","article-title":"Mortality from malaria in France, 2005 to 2014","volume":"25","author":"Kendjo","year":"2020","journal-title":"Euro Surveill"},{"key":"10.1016\/j.tmaid.2026.103031_bib6","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.medmal.2019.06.002","article-title":"Changes in malaria epidemiology in France and worldwide, 2000\u20132015","volume":"50","author":"Thellier","year":"2020","journal-title":"M\u00e9decine Mal Infect"},{"key":"10.1016\/j.tmaid.2026.103031_bib7","first-page":"S7","article-title":"Paludisme autochtone en France hexagonale de 2021 \u00e0 2025 : hausse du nombre de cas","volume":"5","author":"Krug","year":"2026","journal-title":"M\u00e9decine Mal Infect Form"},{"key":"10.1016\/j.tmaid.2026.103031_bib8","series-title":"Prise en charge et pr\u00e9vention du paludisme d\u2019importation Mise \u00e0 jour 2017 des RPC 2007","year":"2017"},{"key":"10.1016\/j.tmaid.2026.103031_bib9","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.medmal.2019.07.011","article-title":"Management and treatment of uncomplicated imported malaria in adults. Update of the French malaria clinical guidelines","volume":"50","author":"Epelboin","year":"2020","journal-title":"M\u00e9decine Mal Infect"},{"key":"10.1016\/j.tmaid.2026.103031_bib10","series-title":"Artemisinin resistance and artemisinin-based combination therapy efficacy: status report","year":"2018"},{"key":"10.1016\/j.tmaid.2026.103031_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0264339","article-title":"Therapeutic efficacy of artemether-lumefantrine, artesunate-amodiaquine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Sub-Saharan Africa: a systematic review and meta-analysis","volume":"17","author":"Marwa","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.tmaid.2026.103031_bib12","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s12936-018-2265-x","article-title":"Efficacy and safety of artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Sudan: a systematic review and meta-analysis","volume":"17","author":"Adam","year":"2018","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2026.103031_bib13","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1038\/s41598-018-37113-5","article-title":"Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method","volume":"9","author":"Funck-Brentano","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.tmaid.2026.103031_bib14","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1093\/cid\/ciw710","article-title":"High rate of treatment failures in nonimmune travelers treated with artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria in Sweden: retrospective comparative analysis of effectiveness and case series","volume":"64","author":"Sond\u00e9n","year":"2017","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.tmaid.2026.103031_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.tmaid.2023.102549","article-title":"Artemether-lumefantrine, mefloquine and atovaquone-proguanil in the treatment of uncomplicated Plasmodium falciparum malaria in travellers: a retrospective comparative study of efficacy and treatment failures","volume":"52","author":"Grebenyuk","year":"2023","journal-title":"Travel Med Infect Dis"},{"key":"10.1016\/j.tmaid.2026.103031_bib16","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The strengthening the reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"61","author":"Von Elm","year":"2008","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.tmaid.2026.103031_bib17","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1186\/1475-2875-12-399","article-title":"Atovaquone-proguanil in the treatment of imported uncomplicated Plasmodium falciparum malaria: a prospective observational study of 553 cases","volume":"12","author":"Cordel","year":"2013","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2026.103031_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actatropica.2018.10.007","article-title":"Effect of Plasmodium falciparum infection on blood parameters and their association with clinical severity in adults of Odisha, India","volume":"190","author":"Dhangadamajhi","year":"2019","journal-title":"Acta Trop"},{"key":"10.1016\/j.tmaid.2026.103031_bib19","volume":". 81","author":"Rubin","year":"2004"},{"key":"10.1016\/j.tmaid.2026.103031_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.imu.2023.101382","article-title":"A comparison of imputation methods for categorical data","volume":"42","author":"Memon","year":"2023","journal-title":"Inform Med Unlocked"},{"key":"10.1016\/j.tmaid.2026.103031_bib21","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1186\/s12936-016-1364-9","article-title":"The Imported malaria hospitalization study group. Hospitalization and ambulatory care in imported-malaria: evaluation of trends and impact on mortality. A prospective multicentric 14-year observational study","volume":"15","author":"Casalino","year":"2016","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2026.103031_bib22","article-title":"New guidelines reduce the risk of hospitalization for adult patients with uncomplicated Plasmodium falciparum malaria: an observational, multicenter, retrospective French study","volume":"54","author":"Oceane Minka","year":"2024","journal-title":"Infect Dis Now"},{"key":"10.1016\/j.tmaid.2026.103031_bib23","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1186\/s12916-015-0324-5","article-title":"The clinical implications of thrombocytopenia in adults with severe falciparum malaria: a retrospective analysis","volume":"13","author":"Hanson","year":"2015","journal-title":"BMC Med"},{"key":"10.1016\/j.tmaid.2026.103031_bib24","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1182\/blood-2018-08-865618","article-title":"Platelets in malaria pathogenesis","volume":"132","author":"O'Sullivan","year":"2018","journal-title":"Blood"},{"key":"10.1016\/j.tmaid.2026.103031_bib25","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.actatropica.2009.10.011","article-title":"Factors contributing to anaemia after uncomplicated Plasmodium falciparum malaria in children","volume":"113","author":"Sowunmi","year":"2010","journal-title":"Acta Trop"},{"key":"10.1016\/j.tmaid.2026.103031_bib26","doi-asserted-by":"crossref","first-page":"614","DOI":"10.4269\/ajtmh.2001.65.614","article-title":"Factors contributing to anemia after uncomplicated falciparum malaria","volume":"65","author":"Price","year":"2001","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.tmaid.2026.103031_bib27","doi-asserted-by":"crossref","DOI":"10.1093\/jtm\/taad001","article-title":"Post-treatment haemolysis is common following oral artemisinin combination therapy of uncomplicated malaria in travellers","volume":"30","author":"Kurth","year":"2023","journal-title":"J Trav Med"},{"key":"10.1016\/j.tmaid.2026.103031_bib28","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2021-245718","article-title":"Fatal case of delayed-onset haemolytic anaemia after oral artemether\u2013lumefantrine","volume":"14","author":"Gustafsson","year":"2021","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.tmaid.2026.103031_bib29","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1080\/00034983.2000.11813577","article-title":"Comparative clinical characteristics and response to oral antimalarial therapy of children with and without Plasmodium falciparum hyperparasitaemia in an endemic area","volume":"94","author":"Sowunmi","year":"2000","journal-title":"Ann Trop Med Parasitol"},{"key":"10.1016\/j.tmaid.2026.103031_bib30","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.tmaid.2017.04.008","article-title":"Comparing imported malaria in adults and children presenting to an Italian teaching hospital: a 10-year retrospective study","volume":"17","author":"Luise","year":"2017","journal-title":"Travel Med Infect Dis"},{"key":"10.1016\/j.tmaid.2026.103031_bib31","first-page":"44","article-title":"Clinical and laboratory profile of hospitalized malarial patients: an agra-based Study","volume":"64","author":"Deshwal","year":"2016","journal-title":"J Assoc Phys India"},{"key":"10.1016\/j.tmaid.2026.103031_bib32","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/j.1708-8305.2011.00554.x","article-title":"Diagnosis and therapy for hospitalized imported malaria in adults in Italy","volume":"18","author":"Antinori","year":"2011","journal-title":"J Trav Med"},{"key":"10.1016\/j.tmaid.2026.103031_bib33","article-title":"Imported malaria: a 20-year retrospective study from a tertiary public hospital in Brussels, Belgium","volume":"54","author":"Leys","year":"2024","journal-title":"Infect Dis Now"},{"key":"10.1016\/j.tmaid.2026.103031_bib34","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.4269\/ajtmh.20-0299","article-title":"Epidemiology of Plasmodium falciparum malaria and risk factors for severe disease in Hubei Province, China","volume":"103","author":"Xia","year":"2020","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.tmaid.2026.103031_bib35","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.1691","article-title":"Epidemiologic trends in malaria incidence among travelers returning to Metropolitan France, 1996-2016","volume":"2","author":"Kendjo","year":"2019","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.tmaid.2026.103031_bib36","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1186\/s12936-017-2007-5","article-title":"Epidemiological and clinical assessment of a shared territorial malaria guideline in the 10 years of its implementation (Barcelona, North Metropolitan Area, Catalonia, Spain, 2007\u20132016)","volume":"16","author":"M\u00f2dol","year":"2017","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2026.103031_bib37","doi-asserted-by":"crossref","first-page":"e13","DOI":"10.1016\/j.ejim.2018.07.024","article-title":"Epidemiological and clinical characteristics of imported malaria in adults in Milan, Italy, 2010\u20132015","volume":"57","author":"Antinori","year":"2018","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.tmaid.2026.103031_bib38","doi-asserted-by":"crossref","DOI":"10.1093\/jtm\/tax081","article-title":"Imported malaria in northern Italy: epidemiology and clinical features observed over 18 years in the teaching hospital of brescia","volume":"25","author":"Zanotti","year":"2018","journal-title":"J Trav Med"},{"key":"10.1016\/j.tmaid.2026.103031_bib39","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s12936-020-3104-4","article-title":"A systematic review of factors affecting adherence to malaria chemoprophylaxis amongst travellers from non-endemic countries","volume":"19","author":"Ahluwalia","year":"2020","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2026.103031_bib40","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.idnow.2022.06.004","article-title":"Should anti-malarial chemoprophylaxis be reimbursed in France? A cost-effectiveness analysis of different reimbursement strategies","volume":"52","author":"Fiorina","year":"2022","journal-title":"Infect Dis Now"},{"key":"10.1016\/j.tmaid.2026.103031_bib41","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0174503","article-title":"Post-licensure safety evaluation of dihydroartemisinin piperaquine in the three major ecological zones across Ghana","volume":"12","author":"Oduro","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.tmaid.2026.103031_bib42","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s12936-016-1099-7","article-title":"Treatment outcomes in a safety observational study of dihydroartemisinin\/piperaquine (Eurartesim\u00ae) in the treatment of uncomplicated malaria at public health facilities in four African countries","volume":"15","author":"Adjei","year":"2016","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2026.103031_bib43","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1186\/s12936-024-05082-y","article-title":"Therapeutic efficacy and safety of artemether-lumefantrine combination therapy for the treatment of uncomplicated Plasmodium falciparum malaria at Teda Health Centre, northwest Ethiopia, 2022\/23","volume":"23","author":"Woldesenbet","year":"2024","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2026.103031_bib44","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1186\/s12936-018-2494-z","article-title":"Efficacy of artemether\u2013lumefantrine and dihydroartemisinin\u2013piperaquine for the treatment of uncomplicated malaria in Papua New Guinea","volume":"17","author":"Tavul","year":"2018","journal-title":"Malar J"},{"key":"10.1016\/j.tmaid.2026.103031_bib45","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1186\/s12936-026-05931-y","article-title":"Efficacy of artemether-lumefantrine for uncomplicated plasmodium falciparum malaria treatment in Mozambique: a systematic review and meta-analysis","volume":"25","author":"Nhama","year":"2026","journal-title":"Malar J"}],"container-title":["Travel Medicine and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1477893926000815?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1477893926000815?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:32:41Z","timestamp":1792726361000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1477893926000815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":45,"alternative-id":["S1477893926000815"],"URL":"https:\/\/doi.org\/10.1016\/j.tmaid.2026.103031","relation":{},"ISSN":["1477-8939"],"issn-type":[{"value":"1477-8939","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Management of uncomplicated Plasmodium falciparum malaria with artemisinin-based combination therapy: Factors associated with hospitalization and clinical, biological, and parasitological outcomes","name":"articletitle","label":"Article Title"},{"value":"Travel Medicine and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tmaid.2026.103031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"103031"}}