{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T11:38:01Z","timestamp":1792582681910,"version":"4.5.0"},"reference-count":48,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T00:00:00Z","timestamp":1747958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["09150172010047"],"award-info":[{"award-number":["09150172010047"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009425","name":"Landsteiner Foundation for Blood Transfusion Research","doi-asserted-by":"publisher","award":["1931F"],"award-info":[{"award-number":["1931F"]}],"id":[{"id":"10.13039\/100009425","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012023","name":"Stichting Sanquin Bloedvoorziening","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012023","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019573","name":"Amsterdam University Medical Centers","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019573","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003180","name":"UvA-Amsterdam UMC","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003180","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine Reviews"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.tmrv.2025.150904","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T11:27:55Z","timestamp":1747999675000},"page":"150904","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Combinations of Non-di(2-ethylhexyl) Phthalate Collection Sets, Storage Bags and Additive Solutions for Red Blood Cells"],"prefix":"10.1016","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4923-2289","authenticated-orcid":false,"given":"Stefan F.","family":"van Wonderen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christie","family":"Vermeulen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Lagerberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3453-7186","authenticated-orcid":false,"given":"Alexander P.J.","family":"Vlaar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas R.L.","family":"Klei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tmrv.2025.150904_bib0001","first-page":"82","article-title":"Red blood cell storage: the story so far","volume":"8","author":"D'Alessandro","year":"2010","journal-title":"Blood Transfus"},{"key":"10.1016\/j.tmrv.2025.150904_bib0002","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/j.1423-0410.1984.tb01603.x","article-title":"Invention and development of the blood bag","volume":"47","author":"Walter","year":"1984","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0003","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1056\/NEJM197211302872203","article-title":"Migration of a phthalate ester plasticizer from polyvinyl chloride blood bags into stored human blood and its localization in human tissues","volume":"287","author":"Jaeger","year":"1972","journal-title":"N Engl J Med"},{"key":"10.1016\/j.tmrv.2025.150904_bib0004","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1126\/science.170.3956.460","article-title":"Plasticizers from plastic devices extraction, metabolism, and accumulation by biological systems","volume":"170","author":"Jaeger","year":"1970","journal-title":"Science"},{"key":"10.1016\/j.tmrv.2025.150904_bib0005","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1182\/bloodadvances.2018029629","article-title":"Effects of aged stored autologous red blood cells on human plasma metabolome","volume":"3","author":"D'Alessandro","year":"2019","journal-title":"Blood Adv"},{"key":"10.1016\/j.tmrv.2025.150904_bib0006","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1182\/blood.V64.6.1270.1270","article-title":"Characterization of erythrocyte quality during the refrigerated storage of whole blood containing di-(2-ethylhexyl) phthalate","volume":"64","author":"Estep","year":"1984","journal-title":"Blood"},{"key":"10.1016\/j.tmrv.2025.150904_bib0007","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1046\/j.1537-2995.1984.24685066808.x","article-title":"Incorporation of plasticizer into red cells during storage","volume":"24","author":"Rock","year":"1984","journal-title":"Transfusion"},{"key":"10.1016\/j.tmrv.2025.150904_bib0008","first-page":"150","article-title":"Stabilization of red blood cells by the plasticizer, diethylhexylphthalate","volume":"48","author":"Horowitz","year":"1985","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0009","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1182\/blood.V71.2.448.448","article-title":"The effect of the plasticizer di-2-ethylhexyl phthalate on the survival of stored RBCs","volume":"71","author":"AuBuchon","year":"1988","journal-title":"Blood"},{"key":"10.1016\/j.tmrv.2025.150904_bib0010","doi-asserted-by":"crossref","first-page":"11899","DOI":"10.1021\/acs.langmuir.0c01964","article-title":"Stabilization of lipid membranes through partitioning of the blood bag plasticizer di-2-ethylhexyl phthalate (DEHP)","volume":"36","author":"Bider","year":"2020","journal-title":"Langmuir"},{"key":"10.1016\/j.tmrv.2025.150904_bib0011","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.yrtph.2016.01.013","article-title":"The safety of medical devices containing DEHP plasticized PVC or other plasticizers on neonates and other groups possibly at risk (2015 update)","volume":"76","author":"Testai","year":"2016","journal-title":"Regul Toxicol Pharmacol"},{"key":"10.1016\/j.tmrv.2025.150904_bib0012","unstructured":"SCENIHR (Scientific Committee on Emerging and Newly-Identified Health Risks), Scientific Opinion on the safety of medical devices containing DEHP-plasticized PVC or other plasticizers on neonates and other groups possibly at risk. 2015. Available from: https:\/\/commission.europa.eu\/, accessed on May 1, 2025."},{"key":"10.1016\/j.tmrv.2025.150904_bib0013","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1186\/s12889-024-17801-w","article-title":"Exposure to di-2-ethylhexyl phthalate (DEHP) increases the risk of cancer","volume":"24","author":"Yang","year":"2024","journal-title":"BMC Public Health"},{"key":"10.1016\/j.tmrv.2025.150904_bib0014","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1289\/ehp.6202","article-title":"In utero exposure to di-(2-ethylhexyl)phthalate and duration of human pregnancy","volume":"111","author":"Latini","year":"2003","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.tmrv.2025.150904_bib0015","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1289\/ehp.9852","article-title":"Di(2-ethylhexyl) phthalate metabolites may alter thyroid hormone levels in men","volume":"115","author":"Meeker","year":"2007","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.tmrv.2025.150904_bib0016","series-title":"Opinion of the Member State Committee on ECHA\u2019s draft recommendation for the first amendment of existing entries in Annex XIV of the REACH Regulation Final","year":"2019"},{"key":"10.1016\/j.tmrv.2025.150904_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.yrtph.2019.104546","article-title":"Guidelines on the benefit-risk assessment of the presence of phthalates in certain medical devices covering phthalates which are carcinogenic, mutagenic, toxic to reproduction (CMR) or have endocrine-disrupting (ED) properties","volume":"111","author":"De Jong","year":"2020","journal-title":"Regulat Toxicol Pharmacol"},{"key":"10.1016\/j.tmrv.2025.150904_bib0018","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/vox.12099","article-title":"Should DEHP be eliminated in blood bags?","volume":"106","author":"van der Meer","year":"2014","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0019","first-page":"199","article-title":"Survival of red cells stored for 21 and 35 days in a non-di-(2-ethylhexyl)phthalate plastic container","volume":"53","author":"Myhre","year":"1987","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0020","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/vox.12472","article-title":"Storage of red blood cells in a novel polyolefin blood container: a pilot in vitro study","volume":"112","author":"Gulliksson","year":"2017","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0021","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1111\/trf.14583","article-title":"In vitro evaluation of di(2-ethylhexyl)terephthalate-plasticized polyvinyl chloride blood bags for red blood cell storage in AS-1 and PAGGSM additive solutions","volume":"58","author":"Graminske","year":"2018","journal-title":"Transfusion"},{"key":"10.1016\/j.tmrv.2025.150904_bib0022","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/vox.12982","article-title":"Non-phthalate plasticizer DEHT preserves adequate blood component quality during storage in PVC blood bags","volume":"116","author":"Larsson","year":"2021","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0023","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1111\/trf.12870","article-title":"In vitro evaluation of the quality of blood products collected and stored in systems completely free of di(2-ethylhexyl)phthalate-plasticized materials","volume":"55","author":"Lagerberg","year":"2015","journal-title":"Transfusion"},{"key":"10.1016\/j.tmrv.2025.150904_bib0024","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1111\/vox.13344","article-title":"Clinical and in vitro evaluation of red blood cells collected and stored in a non-DEHP plasticized bag system","volume":"117","author":"Vermeulen","year":"2022","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0025","article-title":"An evaluation of diethylhexyl phthalate free top & bottom in-line blood collection set with a new soft housing filter","author":"Danilova","year":"2024","journal-title":"Transfus Med"},{"key":"10.1016\/j.tmrv.2025.150904_bib0026","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/vox.13177","article-title":"DEHT is a suitable plasticizer option for phthalate-free storage of irradiated red blood cells","volume":"117","author":"Larsson","year":"2022","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0027","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1159\/000535625","article-title":"In vitro evaluation of DINCH-plasticized blood bags for red blood cell storage with CPDA-1 anticoagulant","volume":"51","author":"Kim","year":"2024","journal-title":"Transfus Med Hemother"},{"key":"10.1016\/j.tmrv.2025.150904_bib0028","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1111\/j.1537-2995.2011.03506.x","article-title":"Exploratory in vitro study of red blood cell storage containers formulated with an alternative plasticizer","volume":"52","author":"Dumont","year":"2012","journal-title":"Transfusion"},{"key":"10.1016\/j.tmrv.2025.150904_bib0029","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0185737","article-title":"Pilot study on novel blood containers with alternative plasticizers for red cell concentrate storage","volume":"12","author":"Morishita","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.tmrv.2025.150904_bib0030","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1159\/000441639","article-title":"Blood bag plasticizers influence red Blood cell vesiculation rate without altering the lipid composition of the vesicles","volume":"43","author":"Bicalho","year":"2016","journal-title":"Transfus Med Hemother"},{"key":"10.1016\/j.tmrv.2025.150904_bib0031","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/vox.12355","article-title":"An investigation of red blood cell concentrate quality during storage in paediatric-sized polyvinylchloride bags plasticized with alternatives to di-2-ethylhexyl phthalate (DEHP)","volume":"110","author":"Serrano","year":"2016","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0032","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1111\/vox.13258","article-title":"C. Biomedical Excellence for Safer Transfusion, survey of blood centre readiness regarding removal of DEHP from blood bag sets: the BEST Collaborative Study","volume":"117","author":"Razatos","year":"2022","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0033","first-page":"456","article-title":"Prevention of red cell storage lesion: a comparison of five different additive solutions","volume":"15","author":"Lagerberg","year":"2017","journal-title":"Blood Transfus"},{"key":"10.1016\/j.tmrv.2025.150904_bib0034","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/vox.13384","article-title":"Recommendations for in vitro evaluation of blood components collected, prepared and stored in non-DEHP medical devices","volume":"118","author":"Klei","year":"2023","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0035","doi-asserted-by":"crossref","DOI":"10.3390\/metabo11020094","article-title":"Comparative effects of di-(2-ethylhexyl)phthalate and di-(2-ethylhexyl)terephthalate metabolites on thyroid receptors: in Vitro and In Silico studies","volume":"11","author":"Kambia","year":"2021","journal-title":"Metabolites"},{"key":"10.1016\/j.tmrv.2025.150904_bib0036","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/bdrb.20108","article-title":"Two-generation reproduction study of di-2-ethylhexyl terephthalate in crl:CD rats","volume":"80","author":"Faber","year":"2007","journal-title":"Birth Defects Res B Dev Reprod Toxicol"},{"key":"10.1016\/j.tmrv.2025.150904_bib0037","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1002\/bdrb.20130","article-title":"Developmental toxicity and uterotrophic studies with di-2-ethylhexyl terephthalate","volume":"80","author":"Faber","year":"2007","journal-title":"Birth Defects Res B Dev Reprod Toxicol"},{"key":"10.1016\/j.tmrv.2025.150904_bib0038","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.toxlet.2011.04.020","article-title":"Systemic toxicity of di-2-ethylhexyl terephthalate (DEHT) in rodents following four weeks of intravenous exposure","volume":"205","author":"Wirnitzer","year":"2011","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.tmrv.2025.150904_bib0039","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1423-0410.2011.01479.x","article-title":"Effect of X-irradiation on the quality of red cell concentrates","volume":"101","author":"Bashir","year":"2011","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0040","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1002\/app.25760","article-title":"Substitution of di (2-ethylhexyl) phthalate by di (isononyl) cyclohexane-1, 2-dicarboxylate as a plasticizer for industrial vinyl plastisol formulations","volume":"104","author":"Crespo","year":"2007","journal-title":"J Appl Pol Sci"},{"key":"10.1016\/j.tmrv.2025.150904_bib0041","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/vox.12084","article-title":"C. Biomedical excellence for safer transfusion, commercially available blood storage containers","volume":"106","author":"Prowse","year":"2014","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0042","first-page":"8","article-title":"The in vitro and in vivo evaluation of whole blood and red cell concentrates drawn on CPDA-1 and stored in a non-DEHP plasticized PVC container","volume":"61","author":"Seidl","year":"1991","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0043","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1046\/j.1537-2995.1991.31191096180.x","article-title":"Storage of saline-adenine-glucose-mannitol-suspended red cells in a new plastic container: polyvinylchloride plasticized with butyryl-n-trihexyl-citrate","volume":"31","author":"Hogman","year":"1991","journal-title":"Transfusion"},{"key":"10.1016\/j.tmrv.2025.150904_bib0044","doi-asserted-by":"crossref","DOI":"10.1111\/vox.70019","article-title":"Clinical evaluation of red cell concentrates in non-DEHP plasticized containers compared with standard DEHP plasticized containers: a quasi-randomized observational multicentre study","author":"Vermeulen","year":"2025","journal-title":"Vox Sang"},{"key":"10.1016\/j.tmrv.2025.150904_bib0045","first-page":"227","article-title":"Reporting transfusion-related acute lung injury by clinical and preclinical disciplines","volume":"16","author":"Peters","year":"2018","journal-title":"Blood Transfus"},{"key":"10.1016\/j.tmrv.2025.150904_bib0046","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/j.1537-2995.2009.02415.x","article-title":"The practice of reporting transfusion-related acute lung injury: a national survey among clinical and preclinical disciplines","volume":"50","author":"Vlaar","year":"2010","journal-title":"Transfusion"},{"key":"10.1016\/j.tmrv.2025.150904_bib0047","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1093\/bja\/aeg101","article-title":"Transfusion-related acute lung injury (TRALI)\u2013under-diagnosed and under-reported","volume":"90","author":"Wallis","year":"2003","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.tmrv.2025.150904_bib0048","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.htct.2024.01.004","article-title":"Underreporting of transfusion incidents","volume":"46","author":"Garcia","year":"2024","journal-title":"Hematol Transfus Cell Ther"}],"container-title":["Transfusion Medicine Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088779632500029X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088779632500029X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:25:35Z","timestamp":1753878335000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S088779632500029X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":48,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S088779632500029X"],"URL":"https:\/\/doi.org\/10.1016\/j.tmrv.2025.150904","relation":{},"ISSN":["0887-7963"],"issn-type":[{"value":"0887-7963","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Combinations of Non-di(2-ethylhexyl) Phthalate Collection Sets, Storage Bags and Additive Solutions for Red Blood Cells","name":"articletitle","label":"Article Title"},{"value":"Transfusion Medicine Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tmrv.2025.150904","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"150904"}}