{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:17:29Z","timestamp":1791224249007,"version":"4.1.0"},"reference-count":19,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,4,1]],"date-time":"2005-04-01T00:00:00Z","timestamp":1112313600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,4,1]],"date-time":"2005-04-01T00:00:00Z","timestamp":1112313600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology"],"published-print":{"date-parts":[[2005,4]]},"DOI":"10.1016\/j.tox.2004.12.020","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T19:44:46Z","timestamp":1109447086000},"page":"185-187","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":222,"title":["X-ray contrast media\u2014an overview"],"prefix":"10.1016","volume":"209","author":[{"given":"Cathrine","family":"Christiansen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl. 1","key":"10.1016\/j.tox.2004.12.020_bib1","doi-asserted-by":"crossref","first-page":"S37","DOI":"10.1097\/00004424-199405001-00007","article-title":"The etiology of contrast medium reactions","volume":"29","author":"Alm\u00e9n","year":"1994","journal-title":"Invest. Radiol."},{"key":"10.1016\/j.tox.2004.12.020_bib2","unstructured":"Amersham Health, 2002. Annual Report."},{"key":"10.1016\/j.tox.2004.12.020_bib3","doi-asserted-by":"crossref","first-page":"180","DOI":"10.2165\/00003088-199732030-00002","article-title":"An overview of the clinical pharmacokinetics of X-ray contrast media","volume":"32","author":"Bourin","year":"1997","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.tox.2004.12.020_bib4","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1007\/s003300000543","article-title":"Delayed allergy-like reactions to X-ray contrast media: mechanistic considerations","volume":"10","author":"Christiansen","year":"2000","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.tox.2004.12.020_bib5","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1148\/radiology.183.1.1549655","article-title":"Delayed reactions to contrast media after interleukin-2 immunotheraphy","volume":"183","author":"Choyke","year":"1992","journal-title":"Radiology"},{"key":"10.1016\/j.tox.2004.12.020_bib6","first-page":"39","article-title":"Delayed adverse reactions to iodinated contrast media and their risk factors","volume":"18","author":"Hosoya","year":"2000","journal-title":"Radiat. Med."},{"key":"10.1016\/j.tox.2004.12.020_bib7","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1148\/radiology.175.3.2343107","article-title":"Adverse reactions to ionic and nonionic contrast media. A report from the Japanese Committee on the Safety of Contrast Media","volume":"175","author":"Katayama","year":"1990","journal-title":"Radiology"},{"key":"10.1016\/j.tox.2004.12.020_bib8","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1111\/j.1365-2133.2003.05763.x","article-title":"Severe Stevens\u2013Johnson syndrome induced by contrast medium iopentol (Imagopaque\u00ae)","volume":"150","author":"Laffitte","year":"2004","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.tox.2004.12.020_bib9","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1259\/0007-1285-62-735-260","article-title":"A large trial of intravenous Conray 325 and Niopam 300 to assess immediate and delayed reactions","volume":"62","author":"McCullough","year":"1989","journal-title":"Br. J. Radiol."},{"key":"10.1016\/j.tox.2004.12.020_bib10","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s00330-002-1339-9","article-title":"A prospective survey of delayed adverse reactions to iohexol in urography and computed tomography","volume":"13","author":"Munechika","year":"2003","journal-title":"Eur. Radiat."},{"key":"10.1016\/j.tox.2004.12.020_bib11","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1111\/j.1440-1673.1988.tb02770.x","article-title":"The RACR survey of intravenous contrast media reactions. Final report","volume":"32","author":"Palmer","year":"1988","journal-title":"Australas Radiol."},{"key":"10.1016\/j.tox.2004.12.020_bib12","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1080\/02841859809172442","article-title":"Late allergy-like reactions following vascular administration of radiography contrast media","volume":"39","author":"Pedersen","year":"1998","journal-title":"Acta Radiol."},{"key":"10.1016\/j.tox.2004.12.020_bib13","doi-asserted-by":"crossref","first-page":"262","DOI":"10.2214\/ajr.176.1.1760262","article-title":"Toxic epidermal necrolysis after repeated injections of iohexol","volume":"176","author":"Rosado","year":"2001","journal-title":"Am. J. Roentgenol."},{"key":"10.1016\/j.tox.2004.12.020_bib14","first-page":"219","article-title":"Frequency of late allergy-like reactions following injection of intravascular non-ionic contrast media. A retrospective study comparing a non-ionic monomeric contrast medium with a non-ionic dimeric contrast medium","volume":"39","author":"Rydberg","year":"1998","journal-title":"Acta Radiol."},{"key":"10.1016\/j.tox.2004.12.020_bib15","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1136\/pgmj.64.751.392","article-title":"Fatal Stevens\u2013Johnson syndrome following urography with iopamidol in systemic lupus erythematosus","volume":"64","author":"Savill","year":"1988","journal-title":"Postgrad. Med. J."},{"key":"10.1016\/j.tox.2004.12.020_bib16","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1259\/bjr\/26964464","article-title":"Contrast media and the kidney: European society of urogenital radiology (ESUR) guidelines","volume":"76","author":"Thomsen","year":"2003","journal-title":"Br. J. Radiol."},{"key":"10.1016\/j.tox.2004.12.020_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00004424-199801000-00001","article-title":"Delayed adverse reactions to nonionic monomeric contrast-enhanced media","volume":"33","author":"Yasuda","year":"1998","journal-title":"Invest. Radiol."},{"key":"10.1016\/j.tox.2004.12.020_bib18","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.6009\/jjrt.KJ00003500878","article-title":"A retrospective survey of delayed adverse reactions to ionic and nonionic contrast media","volume":"52","author":"Yamaguchi","year":"1992","journal-title":"Nippon Igaku Hoshasen Gakkai Zasshi"},{"key":"10.1016\/j.tox.2004.12.020_bib19","doi-asserted-by":"crossref","first-page":"939","DOI":"10.2214\/ajr.152.5.939","article-title":"A prospective trial of ionic vs nonionic contrast agents in routine clinical practice: comparison of adverse effects","volume":"152","author":"Wolf","year":"1989","journal-title":"Am. J. Roentgenol."}],"container-title":["Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X0400719X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X0400719X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T22:51:49Z","timestamp":1759531909000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300483X0400719X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,4]]}},"alternative-id":["S0300483X0400719X"],"URL":"https:\/\/doi.org\/10.1016\/j.tox.2004.12.020","relation":{},"ISSN":["0300-483X"],"issn-type":[{"value":"0300-483X","type":"print"}],"subject":[],"published":{"date-parts":[[2005,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"X-ray contrast media\u2014an overview","name":"articletitle","label":"Article Title"},{"value":"Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tox.2004.12.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}