{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T03:48:54Z","timestamp":1789444134710,"version":"build-2803163510"},"reference-count":58,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1016\/j.tox.2006.12.011","type":"journal-article","created":{"date-parts":[[2006,12,18]],"date-time":"2006-12-18T07:02:38Z","timestamp":1166425358000},"page":"79-88","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Adjuvant effects of inhaled mono-2-ethylhexyl phthalate in BALB\/cJ mice"],"prefix":"10.1016","volume":"232","author":[{"given":"Jitka Stilund","family":"Hansen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren Thor","family":"Larsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars K.","family":"Poulsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunnar Damg\u00e5rd","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tox.2006.12.011_bib1","doi-asserted-by":"crossref","first-page":"2568","DOI":"10.4049\/jimmunol.176.4.2568","article-title":"Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues","volume":"176","author":"Alvarez","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib2","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1002\/(SICI)1521-4141(199802)28:02<681::AID-IMMU681>3.0.CO;2-A","article-title":"Antigen dose-dependent differences in IgE antibody production are not due to polarization towards Th1 and Th2 cell subsets","volume":"28","author":"Arps","year":"1998","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib3","doi-asserted-by":"crossref","first-page":"S466","DOI":"10.1016\/S0091-6749(00)90044-7","article-title":"Prevalence and etiology of asthma","volume":"105","author":"Beasley","year":"2000","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib4","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1289\/ehp.7809","article-title":"Phthalates in indoor dust and their association with building characteristics","volume":"113","author":"Bornehag","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.tox.2006.12.011_bib5","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1289\/ehp.7187","article-title":"The association between asthma and allergic symptoms in children and phthalates in house dust: a nested case\u2013control study","volume":"112","author":"Bornehag","year":"2004","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.tox.2006.12.011_bib6","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/0041-008X(81)90351-3","article-title":"Evaluation of toluene and acetone inhalant abuse. II. Model development and toxicology","volume":"61","author":"Bruckner","year":"1981","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.tox.2006.12.011_bib7","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1189\/jlb.71.3.388","article-title":"The role of PPARs in inflammation and immunity","volume":"71","author":"Clark","year":"2002","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.tox.2006.12.011_bib8","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1159\/000024230","article-title":"Murine allergic respiratory responses to the major house dust mite allergen Der p 1","volume":"120","author":"Clarke","year":"1999","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib9","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1021\/es0347944","article-title":"Emission of di-2-ethylhexyl phthalate from PVC flooring into air and uptake in dust: emission and sorption experiments in FLEC and CLIMPAQ","volume":"38","author":"Clausen","year":"2004","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.tox.2006.12.011_bib10","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0300-483X(02)00583-8","article-title":"Development of sensitisation or tolerance following repeated OVA inhalation in BALB\/cJ mice. Dose-dependency and modulation by the Al(OH)3 adjuvant","volume":"184","author":"Clausen","year":"2003","journal-title":"Toxicology"},{"key":"10.1016\/j.tox.2006.12.011_bib11","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0065-2776(08)60536-2","article-title":"Mechanism and regulation of immunoglobulin isotype switching","volume":"54","author":"Coffman","year":"1993","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib12","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1365-2222.2006.02442.x","article-title":"Inhibition of rBet v 1-induced basophil histamine release with specific immunotherapy-induced serum immunoglobulin G: no evidence that FcgammaRIIB signalling is important","volume":"36","author":"Ejrnaes","year":"2006","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.tox.2006.12.011_bib13","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1097\/01.all.0000191234.97760.88","article-title":"Peptide-based vaccination: where do we stand?","volume":"5","author":"Francis","year":"2005","journal-title":"Curr. Opin. Allergy Clin. Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib14","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1006\/taap.2002.9451","article-title":"Use of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry comparisons of ester vapors","volume":"183","author":"Frederick","year":"2002","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"Suppl. 4","key":"10.1016\/j.tox.2006.12.011_bib15","first-page":"643","article-title":"Environmental tobacco smoke, indoor allergens, and childhood asthma","volume":"108","author":"Gold","year":"2000","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.tox.2006.12.011_bib16","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1034\/j.1600-065X.2001.790118.x","article-title":"IL-5-induced airway eosinophilia\u2014the key to asthma?","volume":"179","author":"Hamelmann","year":"2001","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.tox.2006.12.011_bib17","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1067\/mai.2003.22","article-title":"Inflammatory cells in asthma: mechanisms and implications for therapy","volume":"111","author":"Hamid","year":"2003","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib18","unstructured":"Hansen, J.S., Larsen, S.T., Poulsen, L.K., Nielsen, G.D., 2007. Does lipophilicity per se cause adjuvant effects? Methyl palmitate as model substance does not affect ovalbumin sensitization. J. Toxicol. Environ. Health Part A, in press."},{"key":"10.1016\/j.tox.2006.12.011_bib19","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1046\/j.1365-2222.2001.01081.x","article-title":"Eosinophilic rhinitis accompanies the development of lower airway inflammation and hyper-reactivity in sensitized mice exposed to aerosolized allergen","volume":"31","author":"Hellings","year":"2001","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.tox.2006.12.011_bib20","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.ymeth.2003.08.013","article-title":"Animal models of type I allergy using recombinant allergens","volume":"32","author":"Herz","year":"2004","journal-title":"Methods"},{"key":"10.1016\/j.tox.2006.12.011_bib21","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1111\/j.1365-2222.2005.02191.x","article-title":"Anti-immunoglobulin E treatment with omalizumab in allergic diseases: an update on anti-inflammatory activity and clinical efficacy","volume":"35","author":"Holgate","year":"2005","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.tox.2006.12.011_bib22","first-page":"409","article-title":"Inhibition of specific IgE responses in mice by pre-exposure to inhaled antigen","volume":"42","author":"Holt","year":"1981","journal-title":"Immunology"},{"key":"10.1016\/j.tox.2006.12.011_bib23","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1093\/toxsci\/kfg145","article-title":"Activation of PPARalpha and PPARgamma by environmental phthalate monoesters","volume":"74","author":"Hurst","year":"2003","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tox.2006.12.011_bib24","doi-asserted-by":"crossref","first-page":"188","DOI":"10.2105\/AJPH.89.2.188","article-title":"Interior surface materials in the home and the development of bronchial obstruction in young children in Oslo, Norway","volume":"89","author":"Jaakkola","year":"1999","journal-title":"Am. J. Public Health"},{"key":"10.1016\/j.tox.2006.12.011_bib25","doi-asserted-by":"crossref","first-page":"797","DOI":"10.2105\/AJPH.90.5.797","article-title":"Plastic wall materials in the home and respiratory health in young children","volume":"90","author":"Jaakkola","year":"2000","journal-title":"Am. J. Public Health"},{"key":"10.1016\/j.tox.2006.12.011_bib26","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0890-6238(02)00032-1","article-title":"NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di(2-ethylhexyl) phthalate","volume":"16","author":"Kavlock","year":"2002","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.tox.2006.12.011_bib27","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1289\/ehp.5703","article-title":"Assessment of the inherent allergenic potential of proteins in mice","volume":"111","author":"Kimber","year":"2003","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.tox.2006.12.011_bib28","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1177\/074823378700300212","article-title":"Structure\u2013activity relationships for induction of peroxisomal enzyme activities by phthalate monoesters in primary rat hepatocyte cultures","volume":"3","author":"Lake","year":"1987","journal-title":"Toxicol. Ind. Health"},{"key":"10.1016\/j.tox.2006.12.011_bib29","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1398-9995.2005.00708.x","article-title":"Dendritic cells and the regulation of the allergic immune response","volume":"60","author":"Lambrecht","year":"2005","journal-title":"Allergy"},{"key":"10.1016\/j.tox.2006.12.011_bib30","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1191\/0960327104ht486oa","article-title":"Effects of mono-2-ethylhexyl phthalate on the respiratory tract in BALB\/c mice","volume":"23","author":"Larsen","year":"2004","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.tox.2006.12.011_bib31","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0300-483X(01)00484-X","article-title":"Adjuvant and immuno-suppressive effect of six monophthalates in a subcutaneous injection model with BALB\/c mice","volume":"169","author":"Larsen","year":"2001","journal-title":"Toxicology"},{"key":"10.1016\/j.tox.2006.12.011_bib32","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0378-4274(01)00419-2","article-title":"Di-(2-ethylhexyl) phthalate possesses an adjuvant effect in a subcutaneous injection model with BALB\/c mice","volume":"125","author":"Larsen","year":"2001","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.tox.2006.12.011_bib33","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1159\/000023931","article-title":"Induction of tolerance via the respiratory mucosa","volume":"116","author":"Lowrey","year":"1998","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib34","first-page":"3","article-title":"Epidemiology of rhinitis and asthma","volume":"28","author":"Lundback","year":"1998","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.tox.2006.12.011_bib35","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1126\/science.7916481","article-title":"Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells","volume":"265","author":"McMenamin","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.tox.2006.12.011_bib36","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1073\/pnas.94.4.1344","article-title":"Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma","volume":"94","author":"Mehlhop","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.tox.2006.12.011_bib37","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1111\/j.1365-2222.2005.02362.x","article-title":"Female mice are more susceptible to the development of allergic airway inflammation than male mice","volume":"35","author":"Melgert","year":"2005","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.tox.2006.12.011_bib38","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/1465-9921-7-49","article-title":"Cigarette smoke exposure facilitates allergic sensitization in mice","volume":"7","author":"Moerloose","year":"2006","journal-title":"Respir. Res."},{"key":"10.1016\/j.tox.2006.12.011_bib39","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1159\/000024298","article-title":"Sequential development of airway hyperresponsiveness and acute airway obstruction in a mouse model of allergic inflammation","volume":"121","author":"Neuhaus-Steinmetz","year":"2000","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib40","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1034\/j.1600-0773.2002.900502.x","article-title":"IgE-mediated asthma and rhinitis. I. A role of allergen exposure?","volume":"90","author":"Nielsen","year":"2002","journal-title":"Pharmacol. Toxicol."},{"key":"10.1016\/j.tox.2006.12.011_bib41","unstructured":"Nielsen, G.D., Larsen, S.T., Olsen, O., Lovik, M., Poulsen, L.K., Glue, C., Wolkoff, P. Do indoor chemicals promote development of airway allergy? Indoor Air, in press."},{"key":"10.1016\/j.tox.2006.12.011_bib42","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.tox.2005.07.022","article-title":"IgE-mediated sensitisation, rhinitis and asthma from occupational exposures. Smoking as a model for airborne adjuvants?","volume":"216","author":"Nielsen","year":"2005","journal-title":"Toxicology"},{"key":"10.1016\/j.tox.2006.12.011_bib43","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1471-2172-6-11","article-title":"The allergy adjuvant effect of particles\u2014genetic factors influence antibody and cytokine responses","volume":"6","author":"Nygaard","year":"2005","journal-title":"BMC Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib44","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1289\/ehp.97105972","article-title":"Residential exposure to plasticizers and its possible role in the pathogenesis of asthma","volume":"105","author":"Oie","year":"1997","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.tox.2006.12.011_bib45","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1172\/JCI118560","article-title":"Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin (Ig) E and IgG1 in mice","volume":"97","author":"Oshiba","year":"1996","journal-title":"J. Clin. Invest."},{"issue":"Suppl. 1","key":"10.1016\/j.tox.2006.12.011_bib46","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1289\/ehp.02110s1103","article-title":"Diesel exhaust and asthma: hypotheses and molecular mechanisms of action","volume":"110","author":"Pandya","year":"2002","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.tox.2006.12.011_bib47","doi-asserted-by":"crossref","first-page":"3245","DOI":"10.1096\/fasebj.6.14.1385241","article-title":"A two-signal model for regulation of immunoglobulin isotype switching","volume":"6","author":"Purkerson","year":"1992","journal-title":"FASEB J."},{"key":"10.1016\/j.tox.2006.12.011_bib48","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jaci.2004.11.047","article-title":"Biology of diesel exhaust effects on respiratory function","volume":"115","author":"Riedl","year":"2005","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib49","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1006\/faat.1996.0171","article-title":"Specific antibody responses to subtilisin Carlsberg (Alcalase) in mice: development of an intranasal exposure model","volume":"34","author":"Robinson","year":"1996","journal-title":"Fundam. Appl. Toxicol."},{"key":"10.1016\/j.tox.2006.12.011_bib50","doi-asserted-by":"crossref","first-page":"S441","DOI":"10.1016\/j.jaci.2005.07.001","article-title":"3. Cytokines and chemokines","volume":"117","author":"Steinke","year":"2006","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib51","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1172\/JCI25575","article-title":"IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and Fc gamma RIIb cross-linking","volume":"116","author":"Strait","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.tox.2006.12.011_bib52","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1365-2567.2006.02321.x","article-title":"Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells","volume":"117","author":"Taylor","year":"2006","journal-title":"Immunology"},{"key":"10.1016\/j.tox.2006.12.011_bib53","doi-asserted-by":"crossref","first-page":"4592","DOI":"10.4049\/jimmunol.171.9.4592","article-title":"Early events in peripheral regulatory T cell induction via the nasal mucosa","volume":"171","author":"Unger","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib54","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1002\/1521-4141(200006)30:6<1638::AID-IMMU1638>3.0.CO;2-R","article-title":"Allergen-derived long peptide immunotherapy down-regulates specific IgE response and protects from anaphylaxis","volume":"30","author":"von Garnier","year":"2000","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib55","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.4049\/jimmunol.162.4.1994","article-title":"Intranasally induced immunological tolerance is determined by characteristics of the draining lymph nodes: studies with OVA and human cartilage gp-39","volume":"162","author":"Wolvers","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.tox.2006.12.011_bib56","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/0041-008X(82)90028-X","article-title":"A method for repeated evaluation of pulmonary performance in unanesthetized, unrestrained guinea pigs and its application to detect effects of sulfuric acid mist inhalation","volume":"63","author":"Wong","year":"1982","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.tox.2006.12.011_bib57","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1365-2222.2006.02452.x","article-title":"Components of diesel exhaust particles differentially affect Th1\/Th2 response in a murine model of allergic airway inflammation","volume":"36","author":"Yanagisawa","year":"2006","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.tox.2006.12.011_bib58","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1126\/science.296.5567.490","article-title":"Allergy, parasites, and the hygiene hypothesis","volume":"296","author":"Yazdanbakhsh","year":"2002","journal-title":"Science"}],"container-title":["Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X06007554?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X06007554?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T22:57:33Z","timestamp":1759532253000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300483X06007554"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":58,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["S0300483X06007554"],"URL":"https:\/\/doi.org\/10.1016\/j.tox.2006.12.011","relation":{},"ISSN":["0300-483X"],"issn-type":[{"value":"0300-483X","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adjuvant effects of inhaled mono-2-ethylhexyl phthalate in BALB\/cJ mice","name":"articletitle","label":"Article Title"},{"value":"Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tox.2006.12.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}