{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:56:48Z","timestamp":1791331008880,"version":"4.3.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"1-3","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.tox.2010.08.010","type":"journal-article","created":{"date-parts":[[2010,8,22]],"date-time":"2010-08-22T04:49:54Z","timestamp":1282452594000},"page":"29-37","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Simultaneous analysis of the local and systemic immune responses in mice to study the occupational asthma mechanisms induced by chromium and platinum"],"prefix":"10.1016","volume":"277","author":[{"given":"Masarin","family":"Ban","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Langonn\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mich\u00e8le","family":"Goutet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelly","family":"Huguet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsa","family":"P\u00e9pin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tox.2010.08.010_bib0005","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.jaci.2009.02.030","article-title":"Mechanisms and treatment of allergic disease in the big picture of regulatory T cells","volume":"23","author":"Akdis","year":"2009","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.tox.2010.08.010_bib0010","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.jaci.2007.12.1171","article-title":"Increased activation-induced cell death of high IFN-gamma-producing T(H)1 cells as a mechanism of T(H)2 predominance in atopic diseases","volume":"121","author":"Akkoc","year":"2008","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.tox.2010.08.010_bib0015","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1093\/toxsci\/kfn199","article-title":"The respiratory local lymph node assay as a tool to study respiratory sensitizers","volume":"106","author":"Arts","year":"2008","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tox.2010.08.010_bib0020","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.tox.2005.09.013","article-title":"TDI can induce respiratory allergy with Th-2 dominated response in mice","volume":"218","author":"Ban","year":"2006","journal-title":"Toxicology"},{"key":"10.1016\/j.tox.2010.08.010_bib0025","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.tox.2006.06.012","article-title":"Inhaled chemicals may enhance allergic airway inflammation in ovalbumin-sensitised mice","volume":"266","author":"Ban","year":"2006","journal-title":"Toxicology"},{"key":"10.1016\/j.tox.2010.08.010_bib0030","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/S0091-6749(95)70101-X","article-title":"Hypersensitivity pneumonitis (extrinsic allergic alveolis) induced by isocyanates","volume":"95","author":"Bauer","year":"1995","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.tox.2010.08.010_bib0035","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/BF00378283","article-title":"Prevalence of respiratory allergy in platinum refinery","volume":"64","author":"Bolm-Audorff","year":"1992","journal-title":"Int. Arch. Occup. Environ. Health"},{"key":"10.1016\/j.tox.2010.08.010_bib0040","first-page":"318","article-title":"Platinum allergy","volume":"35","author":"Boggs","year":"1985","journal-title":"Cutis"},{"key":"10.1016\/j.tox.2010.08.010_bib0045","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1398-9995.2004.00521.x","article-title":"Occupational hypersensitivity to metal salts, including platinum, in the secondary industry","volume":"60","author":"Cristaudo","year":"2005","journal-title":"Allergy"},{"key":"10.1016\/j.tox.2010.08.010_bib0050","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1365-2222.1979.tb01529.x","article-title":"Specific IgE antibodies to platinum salts in sensitized workers","volume":"9","author":"Cromwell","year":"1979","journal-title":"Clin. Allergy"},{"key":"10.1016\/j.tox.2010.08.010_bib0055","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1191\/096032701682693062","article-title":"Mechanisms of chromium toxicity, carcinogenicity and allergenicity: review of the literature from 1985 to 2000","volume":"20","author":"Dayan","year":"2001","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.tox.2010.08.010_bib0060","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0278-6915(97)00143-9","article-title":"Selective induction of type 2 cytokines following topical exposure of mice to platinum salts","volume":"36","author":"Dearman","year":"1998","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.tox.2010.08.010_bib0065","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1080\/089583799197131","article-title":"The importance of diluent for airway transport of toluene diisocyanate following intranasal dosing of mice","volume":"11","author":"Ebino","year":"1999","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.tox.2010.08.010_bib0070","first-page":"001","article-title":"Metal allergens of growing significance: epidemiology, immunotoxicology, strategies for testing and prevention","volume":"7","author":"Forte","year":"2008","journal-title":"Inflamm. Allergy: Drug Targets"},{"key":"10.1016\/j.tox.2010.08.010_bib0075","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S1471-4914(02)02302-X","article-title":"Interleukin-5 and eosinophils as therapeutic targets for asthma","volume":"8","author":"Foster","year":"2002","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.tox.2010.08.010_bib0080","first-page":"709","article-title":"Quantitative relationships between sensitising dose of DNCB and reactivity in normal subjects","volume":"53","author":"Friedmann","year":"1983","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.tox.2010.08.010_bib0085","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.toxlet.2008.07.017","article-title":"Use of long term dermal sensitization followed by intratracheal challenge method to identify low-dose chemical-induced respiratory allergic response in mice","volume":"181","author":"Fukuyama","year":"2008","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.tox.2010.08.010_bib0090","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.taap.2004.10.011","article-title":"Identification of contact and respiratory sensitizers using flow cytometry","volume":"205","author":"Goutet","year":"2005","journal-title":"Toxicol Appl. Pharmacol."},{"key":"10.1016\/j.tox.2010.08.010_bib0095","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1097\/00043764-200212000-00013","article-title":"Prevalence and onset of rhinitis in subject with occupational asthma caused by trimellitic anhydride","volume":"44","author":"Grammer","year":"2002","journal-title":"J. Occup. Environ. Med."},{"key":"10.1016\/j.tox.2010.08.010_bib0100","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1183\/09031936.05.00130504","article-title":"Occupational asthma due to manual metal-arc welding of special stainless steels","volume":"26","author":"Hannu","year":"2005","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.tox.2010.08.010_bib0105","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1164\/rccm.200806-893OC","article-title":"\u03b3-Secretase inhibitor reduces allergic pulmonary inflammation by modulating Th1 and Th2 responses","volume":"179","author":"Kang","year":"2009","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.tox.2010.08.010_bib0110","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S1074-7613(00)80439-2","article-title":"Stat 6 is required for mediating response to IL-4 and for development of TH2 cells","volume":"4","author":"Kaplan","year":"1996","journal-title":"Immunity"},{"key":"10.1016\/j.tox.2010.08.010_bib0185","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1164\/ajrccm.149.3.8118626","article-title":"Predictive value of airways hyperresponsiveness and circulating IgE for identifying types of responses to toluene diisocyanate inhalation challenge","volume":"149","author":"Karol","year":"1994","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.tox.2010.08.010_bib0115","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.jaci.2009.02.011","article-title":"IL-2 and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets","volume":"123","author":"L\u00e9tourneau","year":"2009","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.tox.2010.08.010_bib0120","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jaci.2009.01.057","article-title":"Mechanisms of occupational asthma","volume":"123","author":"Maestrelli","year":"2009","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.tox.2010.08.010_bib0125","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/j.1365-2249.2006.03226.x","article-title":"Nickel, cobalt, chromium, palladium and gold induce a mixed Th1- and Th2-type cytokine response in vitro in subjects with contact allergy to the respective metals","volume":"146","author":"Minang","year":"2006","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.tox.2010.08.010_bib0130","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1038\/nnano.2009.151","article-title":"Mechanisms for how inhaled multiwalled carbon nanotubes suppress systemic immune function in mice","volume":"4","author":"Mitchell","year":"2009","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.tox.2010.08.010_bib0135","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.4049\/jimmunol.136.7.2348","article-title":"Two types of murine helper T cell clone. I. Definition according to profile of lymphokine activities and secreted proteins","volume":"136","author":"Mosmann","year":"1986","journal-title":"J. Immunol."},{"key":"10.1016\/j.tox.2010.08.010_bib0140","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/0091-6749(83)90507-9","article-title":"Asthma and IgE antibodies induced by chromium and nickel salts","volume":"72","author":"Novey","year":"1983","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.tox.2010.08.010_bib0145","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/S0952-7915(00)00153-9","article-title":"Regulation of the isotype switch: new insights on cytokine signals and the functions of epsilon germline transcripts","volume":"12","author":"Oettgen","year":"2000","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.tox.2010.08.010_bib0150","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1111\/j.1365-2222.1994.tb00972.x","article-title":"Occupational asthma caused by chromium","volume":"24","author":"Park","year":"1994","journal-title":"Clin. Exp. Allergy"},{"issue":"2","key":"10.1016\/j.tox.2010.08.010_bib0155","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1093\/toxsci\/kfn098","article-title":"Brown Norway rat asthma model of diphenylmethane-4,4\u2032-diisocyanate (MDI): analysis of the elicitation dose-response relationship","volume":"104","author":"Pauluhn","year":"2008","journal-title":"Toxicol Sci."},{"key":"10.1016\/j.tox.2010.08.010_bib0160","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/j.jaci.2006.01.027","article-title":"Validation of a mouse model of chemical-induced asthma using trimellitic anhydride, a respiratory sensitizer, and dinitrochlorobenzene, a dermal sensitizer","volume":"117","author":"Vanoirbeek","year":"2006","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.tox.2010.08.010_bib0165","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1586\/14787210.2.1.59","article-title":"Gene expression patterns and susceptibility to allergic responses","volume":"2","author":"Williams","year":"2006","journal-title":"Exp. Rev. Clin. Immunol."},{"key":"10.1016\/j.tox.2010.08.010_bib0170","unstructured":"World Health Organisation (WHO), 1998. Chromium Environmental Health Criteria No. 61. WHO, Geneva."},{"key":"10.1016\/j.tox.2010.08.010_bib0175","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1165\/rcmb.2007-0078OC","article-title":"IL-9 and IL-13 induce mucus cell metaplasia that is reduced by IFN-\u03b3 in a bax-mediated pathway","volume":"38","author":"Xiang","year":"2008","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.tox.2010.08.010_bib0180","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.jaci.2008.12.1115","article-title":"Antigen-primed splenic CD8+ T cells impede the development of oral antigen-induced allergic diarrhea","volume":"123","author":"Yamada","year":"2009","journal-title":"J. Allergy Clin. Immunol."}],"container-title":["Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X10003288?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X10003288?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T23:12:33Z","timestamp":1759533153000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300483X10003288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":37,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S0300483X10003288"],"URL":"https:\/\/doi.org\/10.1016\/j.tox.2010.08.010","relation":{},"ISSN":["0300-483X"],"issn-type":[{"value":"0300-483X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Simultaneous analysis of the local and systemic immune responses in mice to study the occupational asthma mechanisms induced by chromium and platinum","name":"articletitle","label":"Article Title"},{"value":"Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tox.2010.08.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}