{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T05:18:03Z","timestamp":1791868683886,"version":"4.3.4"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30870454"],"award-info":[{"award-number":["30870454"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31371868"],"award-info":[{"award-number":["31371868"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hundred Talent Project of Shanxi Province in 2015"},{"name":"Science and Technology Innovation Talent Project of Shanxi Province","award":["201605D211031"],"award-info":[{"award-number":["201605D211031"]}]},{"name":"Social Development Project of Shanxi Province","award":["201703D321026-4"],"award-info":[{"award-number":["201703D321026-4"]}]},{"DOI":"10.13039\/501100003398","name":"Shanxi Scholarship Council of China","doi-asserted-by":"publisher","award":["2017-010"],"award-info":[{"award-number":["2017-010"]}],"id":[{"id":"10.13039\/501100003398","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.tox.2018.09.010","type":"journal-article","created":{"date-parts":[[2018,9,29]],"date-time":"2018-09-29T11:19:51Z","timestamp":1538219991000},"page":"122-132","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":69,"special_numbering":"C","title":["Long-term arsenite exposure induces testicular toxicity by redox imbalance, G2\/M cell arrest and apoptosis in mice"],"prefix":"10.1016","volume":"411","author":[{"given":"Qun","family":"Zeng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7763-6977","authenticated-orcid":false,"given":"Huilan","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liqun","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan","family":"An","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tox.2018.09.010_bib0005","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1177\/25.7.893996","article-title":"Dissociation of the mouse testis and characterization of isolated spermatogenic cells","volume":"25","author":"Bellv\u00e9","year":"1977","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.tox.2018.09.010_bib0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tox.2016.09.006","article-title":"Mechanisms underlying effect of the mycotoxin cytochalasin B on induction of cytotoxicity, modulation of cell cycle, Ca2+ homeostasis and ROS production in human breast cells","volume":"370","author":"Chang","year":"2016","journal-title":"Toxicology"},{"key":"10.1016\/j.tox.2018.09.010_bib0015","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.taap.2009.01.010","volume":"239","author":"Chen","year":"2009","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.tox.2018.09.010_bib0020","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s00404-013-2801-4","article-title":"Influence of reactive oxygen species on human sperm functions and fertilizing capacity including therapeutical approaches","volume":"288","author":"Chen","year":"2013","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.tox.2018.09.010_bib0025","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1021\/tx700366x","article-title":"Arsenic trioxide impairs spermatogenesis via reducing gene expression levels in testosterone synthesis pathway","volume":"21","author":"Chiou","year":"2008","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.tox.2018.09.010_bib0030","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.toxlet.2009.03.001","article-title":"Taurine protects rat testes against NaAsO2-induced oxidative stress and apoptosis via mitochondrial dependent and independent pathways","volume":"187","author":"Das","year":"2009","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.tox.2018.09.010_bib0035","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1242\/jcs.115.12.2461","article-title":"From cdc2 to cdk1: when did the cell cycle kinase join its cyclin partner?","volume":"115","author":"Dor\u00e9e","year":"2002","journal-title":"J. Cell. Sci."},{"key":"10.1016\/j.tox.2018.09.010_bib0040","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1262\/jrd.2013-097","article-title":"Resveratrol reverses cadmium chloride-induced testicular damage and subfertility by downregulating p53 and Bax and upregulating gonadotropins and Bcl-2 gene expression","volume":"60","author":"Eleawa","year":"2014","journal-title":"J. Reprod. Dev."},{"key":"10.1016\/j.tox.2018.09.010_bib0045","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1007\/s00244-011-9712-9","article-title":"The effects of di (2-ethylhexyl) phthalate exposure and selenium nutrition on sertoli cell vimentin structure and germ-cell apoptosis in rat testis","volume":"62","author":"Erkekoglu","year":"2012","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.tox.2018.09.010_bib0050","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1177\/0960327111405862","article-title":"Impairment of mice spermatogenesis by sodium arsenite","volume":"31","author":"Ferreira","year":"2012","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.tox.2018.09.010_bib0055","doi-asserted-by":"crossref","first-page":"526","DOI":"10.5732\/cjc.011.10018","article-title":"Mitochondria in cancer: at the crossroads of life and death","volume":"30","author":"Fogg","year":"2011","journal-title":"Chin. J. Cancer"},{"key":"10.1016\/j.tox.2018.09.010_bib0060","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.fct.2017.01.011","article-title":"Effects of six priority controlled phthalate esters with long-term low-dose integrated exposure on male reproductive toxicity in rats","volume":"101","author":"Gao","year":"2017","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.tox.2018.09.010_bib0065","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1095\/biolreprod.103.023705","article-title":"Key role of cyclin dependent kinases in the first and second meiotic divisions of rat spermatocytes","volume":"70","author":"Godet","year":"2004","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.tox.2018.09.010_bib0070","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.kjms.2011.05.003","article-title":"Chronic arsenic toxicity: studies in West Bengal, India","volume":"27","author":"Guha Mazumder","year":"2011","journal-title":"Kaohsiung J. Med. Sci."},{"key":"10.1016\/j.tox.2018.09.010_bib0075","first-page":"2263","article-title":"p53 involvement in control of G2 exit of the cell cycle: role in DNA damage-induced apoptosis","volume":"10","author":"Guillouf","year":"1995","journal-title":"Oncogene"},{"key":"10.1016\/j.tox.2018.09.010_bib0080","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.biopha.2017.09.151","article-title":"Protective role of epigallocatechin-3-gallate on arsenic induced testicular toxicity in Swiss albino mice","volume":"96","author":"Guvvala","year":"2017","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.tox.2018.09.010_bib0085","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1021\/es303522s","article-title":"Risk of arsenic exposure from drinking water and dietary components: implications for risk management in rural Bengal","volume":"47","author":"Halder","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.tox.2018.09.010_bib0090","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.tox.2006.06.010","article-title":"Blood arsenic as a biomarker of arsenic exposure: results from a prospective study","volume":"225","author":"Hall","year":"2006","journal-title":"Toxicology"},{"key":"10.1016\/j.tox.2018.09.010_bib0095","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.canlet.2008.04.041","article-title":"Arsenic trioxide inhibits the growth of Calu-6 cells via inducing a G2 arrest of the cell cycle and apoptosis accompanied with the depletion of GSH","volume":"270","author":"Han","year":"2008","journal-title":"Cancer Lett."},{"key":"10.1016\/j.tox.2018.09.010_bib0100","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/j.jhazmat.2015.08.010","article-title":"Decreased spermatogenesis led to alterations of testis-specific gene expression in male mice following nano-TiO2 exposure","volume":"300","author":"Hong","year":"2015","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.tox.2018.09.010_bib0105","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1289\/ehp.10930","article-title":"Risk of erectile dysfunction induced by arsenic exposure through well water consumption in Taiwan","volume":"116","author":"Hsieh","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.tox.2018.09.010_bib0110","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1111\/and.12472","article-title":"Ameliorative effect of polydatin on oxidative stress-mediated testicular damage by chronic arsenic exposure in rats","volume":"48","author":"Ince","year":"2016","journal-title":"Andrologia"},{"key":"10.1016\/j.tox.2018.09.010_bib0115","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.ejphar.2014.02.039","article-title":"Baicalein attenuates proteasome inhibition-induced apoptosis by suppressing the activation of the mitochondrial pathway and the caspase-8- and Bid-dependent pathways","volume":"730","author":"Jung","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.tox.2018.09.010_bib0120","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.fct.2014.02.024","article-title":"Tetrahydrocurcumin induces G2\/M cell cycle arrest and apoptosis involving p38 MAPK activation in human breast cancer cell","volume":"67","author":"Kang","year":"2014","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.tox.2018.09.010_bib0125","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1007\/s40572-014-0040-x","article-title":"Drinking water arsenic contamination, skin lesions, and malignancies: a systematic review of the global evidence","volume":"2","author":"Karagas","year":"2015","journal-title":"Curr. Environ. Health Rep."},{"key":"10.1016\/j.tox.2018.09.010_bib0130","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.tox.2011.04.013","article-title":"Arsenic trioxide-induced apoptosis in TM4 Sertoli cells: the potential involvement of p21 expression and p53 phosphorylation","volume":"285","author":"Kim","year":"2011","journal-title":"Toxicology"},{"key":"10.1016\/j.tox.2018.09.010_bib0135","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1016\/j.fertnstert.2014.10.020","article-title":"Male infertility testing: reactive oxygen species and antioxidant capacity","volume":"102","author":"Ko","year":"2014","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.tox.2018.09.010_bib0140","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.reprotox.2012.12.005","article-title":"Daily sperm production: application in studies of prenatal exposure to nanoparticles in mice","volume":"36","author":"Kyjovska","year":"2013","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.tox.2018.09.010_bib0145","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.toxlet.2009.05.014","article-title":"1,3- Dinitrobenzene induces apoptosis in TM4 mouse Sertoli cells: involvement of the c-Jun N-terminal kinase (JNK) MAPK pathway","volume":"189","author":"Lee","year":"2009","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.tox.2018.09.010_bib0150","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1093\/toxsci\/kfs169","article-title":"Subchronic exposure to arsenic inhibits spermatogenesis and downregulates the expression of Ddx3y in testis and epididymis of mice","volume":"128","author":"Li","year":"2012","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tox.2018.09.010_bib0155","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.jhazmat.2013.03.058","article-title":"Biomarkers for the evaluation of population health status 16 years after the intervention of arsenic-contaminated groundwater in Xinjiang, China","volume":"262","author":"Liu","year":"2013","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.tox.2018.09.010_bib0160","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.jep.2014.04.013","article-title":"The effect of Lycium barbarum polysaccharides on the male rats\u2019 reproductive system and spermatogenic cell apoptosis exposed to low-dose ionizing irradiation","volume":"154","author":"Luo","year":"2014","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.tox.2018.09.010_bib0165","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.taap.2016.05.003","article-title":"Arsenic trioxide mediates HAPI microglia inflammatory response and subsequent neuron apoptosis through p38\/JNK MAPK\/STAT3 pathway","volume":"303","author":"Mao","year":"2016","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.tox.2018.09.010_bib0170","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1083\/jcb.200811138","article-title":"Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis","volume":"185","author":"Paronetto","year":"2009","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.tox.2018.09.010_bib0175","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1002\/(SICI)1521-1878(200005)22:5<423::AID-BIES4>3.0.CO;2-0","article-title":"Germ cell suicide: new insights into apoptosis during spermatogenesis","volume":"22","author":"Print","year":"2000","journal-title":"Bioessays"},{"key":"10.1016\/j.tox.2018.09.010_bib0180","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1177\/0748233709345936","article-title":"Arsenic trioxide inhibits the growth of human lung cancer cell lines via cell cycle arrest and induction of apoptosis at both normoxia and hypoxia","volume":"25","author":"Qu","year":"2009","journal-title":"Toxicol. Ind. Health"},{"key":"10.1016\/j.tox.2018.09.010_bib0185","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s10653-012-9460-4","article-title":"Arsenic contamination: a potential hazard to the affected areas of West Bengal","volume":"35","author":"Rahaman","year":"2013","journal-title":"India. Environ. Geochem. Health"},{"key":"10.1016\/j.tox.2018.09.010_bib0190","first-page":"84","article-title":"Arsenic induced toxicity on testicular tissue of mice","volume":"52","author":"Sanghamitra","year":"2008","journal-title":"Indian J. Physiol. Pharmacol."},{"key":"10.1016\/j.tox.2018.09.010_bib0195","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.ecoenv.2008.04.023","article-title":"Melatonin prevents damage elicited by the organophosphorous pesticide diazinon on mouse sperm DNA","volume":"72","author":"Sarabia","year":"2009","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.tox.2018.09.010_bib0200","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/nprot.2008.73","article-title":"Analyzing real-time PCR data by the comparative C(T) method","volume":"3","author":"Schmittgen","year":"2008","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.tox.2018.09.010_bib0205","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1267\/ahc.11027","article-title":"Immunohistochemical analysis of histone H3 modifications in germ cells during mouse spermatogenesis","volume":"44","author":"Song","year":"2011","journal-title":"Acta Histochem. Cytochem."},{"key":"10.1016\/j.tox.2018.09.010_bib0210","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1093\/toxsci\/kfn236","article-title":"Arsenic and cardiovascular disease","volume":"107","author":"States","year":"2009","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tox.2018.09.010_bib0215","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.envint.2014.04.019","article-title":"Arsenic and selenium toxicity and their interactive effects in humans","volume":"69","author":"Sun","year":"2014","journal-title":"Environ. Int."},{"key":"10.1016\/j.tox.2018.09.010_bib0220","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1038\/sj.onc.1204252","article-title":"Regulation of the G2\/M transition by p53","volume":"20","author":"Taylor","year":"2001","journal-title":"Oncogene"},{"key":"10.1016\/j.tox.2018.09.010_bib0225","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","article-title":"Free radicals and antioxidants in normal physiological functions and human disease","volume":"39","author":"Valko","year":"2007","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.tox.2018.09.010_bib0230","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ecoenv.2010.11.002","article-title":"Arsenic toxicity in mammals and aquatic animals: a comparative biochemical approach","volume":"73","author":"Ventura-Lima","year":"2011","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.tox.2018.09.010_bib0235","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.scitotenv.2016.07.169","article-title":"Low-level environmental arsenic exposure correlates with unexplained male infertility risk","volume":"15","author":"Wang","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.tox.2018.09.010_bib0240","first-page":"306","article-title":"Chapter 12-chemical fact sheets, arsenic","volume":"vol. 1","author":"WHO","year":"2004"},{"key":"10.1016\/j.tox.2018.09.010_bib0245","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1476-069X-11-46","article-title":"Environmental exposure to arsenic may reduce human semen quality: associations derived from a Chinese cross-sectional study","volume":"11","author":"Xu","year":"2012","journal-title":"Environ. Health"},{"key":"10.1016\/j.tox.2018.09.010_bib0250","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.taap.2010.01.001","article-title":"Arsenite induces apoptosis in human mesenchymal stem cells by alterting Bcl-2 family proteins and by activating intrinsic pathway","volume":"244","author":"Yadav","year":"2010","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.tox.2018.09.010_bib0255","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1007\/s00204-012-0864-9","article-title":"Arsenic induces apoptosis in myoblasts through a reactive oxygen species-induced endoplasmic reticulum stress and mitochondrial dysfunction pathway","volume":"86","author":"Yen","year":"2012","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.tox.2018.09.010_bib0260","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.jhazmat.2010.09.057","article-title":"SO2 inhalation modulates the expression of pro-inflammatory and pro-apoptotic genes in rats heart and lung","volume":"15","author":"Yun","year":"2011","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.tox.2018.09.010_bib0265","first-page":"273","article-title":"Myricetin induces G2\/M phase arrest in HepG2 cells by inhibiting the activity of the cyclin B\/Cdc2 complex","volume":"4","author":"Zhang","year":"2011","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.tox.2018.09.010_bib0270","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1095\/biolreprod.105.044610","article-title":"Caspase 2 activity contributes to the initial wave of germ cell apoptosis during the first round of spermatogenesis","volume":"74","author":"Zheng","year":"2006","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.tox.2018.09.010_bib0275","doi-asserted-by":"crossref","first-page":"3007","DOI":"10.1242\/dev.124.15.3007","article-title":"HSP 70-2 is required for CDC2 kinase activity in meiosis I of mouse spermatocytes","volume":"124","author":"Zhu","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.tox.2018.09.010_bib0280","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.fertnstert.2012.11.022","article-title":"Inhibition of ghrelin signaling improves the reproductive phenotype of male ob\/ob mouse","volume":"99","author":"Zhu","year":"2013","journal-title":"Fertil. Steril."}],"container-title":["Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X18303962?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X18303962?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T23:40:29Z","timestamp":1759534829000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300483X18303962"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":56,"alternative-id":["S0300483X18303962"],"URL":"https:\/\/doi.org\/10.1016\/j.tox.2018.09.010","relation":{},"ISSN":["0300-483X"],"issn-type":[{"value":"0300-483X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term arsenite exposure induces testicular toxicity by redox imbalance, G2\/M cell arrest and apoptosis in mice","name":"articletitle","label":"Article Title"},{"value":"Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tox.2018.09.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}