{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T17:40:01Z","timestamp":1790185201112,"version":"4.1.0"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000802","name":"Directorate-General for the Environment","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000802","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.tox.2020.152653","type":"journal-article","created":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T16:12:35Z","timestamp":1607530355000},"page":"152653","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"special_numbering":"C","title":["Metabolic, reproductive and thyroid effects of bis(2-ethylhexyl) phthalate (DEHP) orally administered to male and female juvenile rats at dose levels derived from children biomonitoring study"],"prefix":"10.1016","volume":"449","author":[{"given":"Roberta","family":"Tassinari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Tait","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Busani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Martinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Narciso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Valeri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amalia","family":"Gastaldelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Deodati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cinzia","family":"La Rocca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Maranghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tox.2020.152653_bib0005","doi-asserted-by":"crossref","DOI":"10.1186\/1477-7827-6-4","article-title":"Effects of estradiol and FSH on maturation of the testis in the hypogonadal (hpg) mouse","volume":"6","author":"Baines","year":"2008","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.tox.2020.152653_bib0010","doi-asserted-by":"crossref","first-page":"684","DOI":"10.3389\/fendo.2018.00684","article-title":"Analysis of lipid metabolism, immune function, and Neurobehavior in adult C57BL\/6JxFVB mice after developmental exposure to di (2-ethylhexyl) phthalate","volume":"9","author":"Bastos Sales","year":"2018","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"10.1016\/j.tox.2020.152653_bib0015","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1007\/s00244-009-9317-8","article-title":"Reproductive effects of di(2-ethylhexyl)phthalate in immature male rats and its relation to cholesterol, testosterone, and thyroxin levels","volume":"57","author":"Botelho","year":"2009","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.tox.2020.152653_bib0020","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.fertnstert.2013.04.019","article-title":"Antim\u00fcllerian hormone inhibits follicle-stimulating hormone-induced adenylyl cyclase activation, aromatase expression, and estradiol production in human granulosa-lutein cells","volume":"100","author":"Chang","year":"2013","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.tox.2020.152653_bib0025","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.orcp.2016.05.003","article-title":"Role of adiponectin gene variants, adipokines and hydrometry-based percent body fat in metabolically healthy and abnormal obesity","volume":"12","author":"Chang","year":"2018","journal-title":"Obes. Res. Clin. Pract."},{"key":"10.1016\/j.tox.2020.152653_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.crtox.2020.02.002","article-title":"Intrauterine exposure to diethylhexyl phthalate disrupts gap junctions in the fetal rat testis","author":"Di Lorenzo","year":"2020","journal-title":"Curr. Res. Toxicol."},{"key":"10.1016\/j.tox.2020.152653_bib0035","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1007\/s00204-019-02590-8","article-title":"Transcriptome analysis revealed the mechanism of the metabolic toxicity and susceptibility of di-(2-ethylhexyl)phthalate on adolescent male ICR mice with type 2 diabetes mellitus","volume":"93","author":"Ding","year":"2019","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.tox.2020.152653_bib0040","first-page":"14","article-title":"Effects of long-term in vivo exposure to Di-2-ethylhexylphthalate on thyroid hormones and the TSH\/TSHR signaling pathways in wistar rats","author":"Dong","year":"2017","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.tox.2020.152653_bib0045","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1093\/jn\/130.3.514","article-title":"Food intake, energy balance and serum leptin concentrations in rats fed low-protein diets","volume":"130","author":"Du","year":"2000","journal-title":"J. Nutr."},{"key":"10.1016\/j.tox.2020.152653_bib0050","doi-asserted-by":"crossref","DOI":"10.1186\/s13633-016-0038-2","article-title":"Anti-Mullerian hormone as a marker of steroid and gonadotropin action in the testis of children and adolescents with disorders of the gonadal axis","volume":"2016","author":"Edelsztein","year":"2016","journal-title":"Int. J. Pediatr. Endocrinol."},{"key":"10.1016\/j.tox.2020.152653_bib0055","first-page":"1557","article-title":"European Food,Safety Authority. Management of left-censored data in dietary exposure assessment of chemical substances","volume":"8","author":"EFSA","year":"2010","journal-title":"EFSA J."},{"key":"10.1016\/j.tox.2020.152653_bib0060","article-title":"Update of the risk assessment of di-butylphthalate (DBP), butyl-benzyl-phthalate (BBP), bis(2-ethylhexyl)phthalate (DEHP), di-isononylphthalate (DINP) and di-isodecylphthalate (DIDP) for use in food contact materials","volume":"17","author":"EFSA Panel on Food Contact Materials","year":"2019","journal-title":"EFSA J."},{"key":"10.1016\/j.tox.2020.152653_bib0065","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.toxlet.2017.05.028","article-title":"Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ER\u03b1, ER\u03b2, and AR","volume":"277","author":"Engel","year":"2017","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.tox.2020.152653_bib0070","series-title":"European Union Risk Assessment. Report Bis (2-ethylhexyl) Phthalate (DEHP)","author":"European Commission","year":"2008"},{"key":"10.1016\/j.tox.2020.152653_bib0075","doi-asserted-by":"crossref","first-page":"243","DOI":"10.2903\/j.efsa.2005.243","article-title":"Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Bis(2-ethylhexyl)phthalate (DEHP) for use in food contact materials","volume":"3","author":"European Food Safety Authority","year":"2005","journal-title":"EFSA J."},{"key":"10.1016\/j.tox.2020.152653_bib0080","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1093\/toxsci\/kfp109","article-title":"Transgenerational effects of Di (2-ethylhexyl) phthalate in the male CRL:CD(SD) rat: added value of assessing multiple offspring per litter","volume":"110","author":"Gray","year":"2009","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tox.2020.152653_bib0085","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1080\/1547691X.2019.1649765","article-title":"Di-(2-ethylhexyl)-phthalate interferes with T-follicular helper cell differentiation and cytokine secretion through signaling lymphocytic activation molecule family member-1","volume":"16","author":"Han","year":"2019","journal-title":"J. Immunotoxicol."},{"key":"10.1016\/j.tox.2020.152653_bib0090","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.tox.2019.01.008","article-title":"In utero exposure to di(2-ethylhexyl)phthalate suppresses blood glucose and leptin levels in the offspring of wild-type mice","volume":"415","author":"Hayashi","year":"2019","journal-title":"Toxicology"},{"key":"10.1016\/j.tox.2020.152653_bib0095","doi-asserted-by":"crossref","DOI":"10.1186\/s12199-019-0802-z","article-title":"Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome proliferator-activated receptor alpha: a review","volume":"24","author":"Ito","year":"2019","journal-title":"Environ. Health Prev. Med."},{"key":"10.1016\/j.tox.2020.152653_bib0100","doi-asserted-by":"crossref","first-page":"69","DOI":"10.6065\/apem.2014.19.2.69","article-title":"Phthalate exposure and childhood obesity","volume":"19","author":"Kim","year":"2014","journal-title":"Ann. Pediatr. Endocrinol. Metab."},{"key":"10.1016\/j.tox.2020.152653_bib0105","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.fct.2018.12.010","article-title":"Di-2-ethylhexylphthalate promotes thyroid cell proliferation and DNA damage through activating thyrotropin-receptor-mediated pathways in vitro and in vivo","volume":"124","author":"Kim","year":"2019","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.tox.2020.152653_bib0110","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1467-789X.2006.00270.x","article-title":"The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review","volume":"8","author":"Klok","year":"2007","journal-title":"Obes. Rev."},{"key":"10.1016\/j.tox.2020.152653_bib0115","series-title":"State of the Art Assessment of Endocrine Disruptors: Final Report","author":"Kortenkamp","year":"2011"},{"key":"10.1016\/j.tox.2020.152653_bib0120","doi-asserted-by":"crossref","first-page":"25618","DOI":"10.1007\/s11356-018-2660-4","article-title":"The LIFE PERSUADED project approach on phthalates and bisphenol A biomonitoring in Italian mother-child pairs linking exposure and juvenile diseases","volume":"25","author":"La Rocca","year":"2018","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.tox.2020.152653_bib0125","article-title":"JAK-STAT and feeding","volume":"2","author":"Ladyman","year":"2013","journal-title":"JAKSTAT"},{"key":"10.1016\/j.tox.2020.152653_bib0130","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.tox.2004.09.008","article-title":"Role of PPARalpha in mediating the effects of phthalates and metabolites in the liver","volume":"207","author":"Lapinskas","year":"2005","journal-title":"Toxicology"},{"key":"10.1016\/j.tox.2020.152653_bib0135","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1001\/jama.2009.976","article-title":"Adiponectin levels and risk of type 2 diabetes: a systematic review and meta-analysis","volume":"302","author":"Li","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.tox.2020.152653_bib0140","doi-asserted-by":"crossref","first-page":"12711","DOI":"10.1007\/s11356-015-4567-7","article-title":"DEHP reduces thyroid hormones via interacting with hormone synthesis-related proteins, deiodinases, transthyretin, receptors, and hepatic enzymes in rats","volume":"22","author":"Liu","year":"2015","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.tox.2020.152653_bib0145","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1080\/10937400903094091","article-title":"Reproductive and developmental toxicity of phthalates","volume":"12","author":"Lyche","year":"2009","journal-title":"J. Toxicol. Environ. Health B Crit. Rev."},{"key":"10.1016\/j.tox.2020.152653_bib0150","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.fct.2008.12.003","article-title":"Effects of the food contaminant semicarbazide following oral administration in juvenile Sprague-Dawley rats","volume":"47","author":"Maranghi","year":"2009","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.tox.2020.152653_bib0155","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.fct.2013.05.048","article-title":"Reproductive toxicity and thyroid effects in Sprague Dawley rats exposed to low doses of ethylenethiourea","volume":"59","author":"Maranghi","year":"2013","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.tox.2020.152653_bib0160","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.yrtph.2013.10.004","article-title":"Anti-androgenicity can only be evaluated using a weight of evidence approach","volume":"68","author":"Melching-Kollmu\u00df","year":"2014","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.tox.2020.152653_bib0165","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.jhazmat.2015.05.052","article-title":"DEHP exposure impairs mouse oocyte cyst breakdown and primordial follicle assembly through estrogen receptor-dependent and independent mechanisms","volume":"298","author":"Mu","year":"2015","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.tox.2020.152653_bib0170","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.reprotox.2017.06.188","article-title":"The juvenile toxicity study as a tool for a science-based risk assessment in the children population group","volume":"72","author":"Narciso","year":"2017","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.tox.2020.152653_bib0175","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1093\/toxsci\/kfp129","article-title":"Pubertal administration of DEHP delays puberty, suppresses testosterone production, and inhibits reproductive tract development in male Sprague-Dawley and Long-Evans rats","volume":"111","author":"Noriega","year":"2009","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tox.2020.152653_bib0180","series-title":"Test No. 416: Two-Generation Reproduction Toxicity","author":"OECD","year":"2001"},{"key":"10.1016\/j.tox.2020.152653_bib0185","series-title":"Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents","author":"OECD","year":"2008"},{"key":"10.1016\/j.tox.2020.152653_bib0190","series-title":"Test No. 414: Prenatal Developmental Toxicity Study","author":"OECD","year":"2018"},{"key":"10.1016\/j.tox.2020.152653_bib0195","series-title":"Test No. 443: Extended One-Generation Reproductive Toxicity Study","author":"OECD","year":"2018"},{"key":"10.1016\/j.tox.2020.152653_bib0200","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.reprotox.2018.06.010","article-title":"Low dose exposure to HBCD, CB-153 or TCDD induces histopathological and hormonal effects and changes in brain protein and gene expression in juvenile female BALB\/c mice","volume":"80","author":"Rasinger","year":"2018","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.tox.2020.152653_bib0205","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/1750368","article-title":"Toxic effects of Di-2-ethylhexyl phthalate: an overview","volume":"2018","author":"Rowdhwal","year":"2018","journal-title":"Biomed Res. Int."},{"key":"10.1016\/j.tox.2020.152653_bib0210","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1080\/10408440600779065","article-title":"Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver","volume":"36","author":"Rusyn","year":"2006","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.tox.2020.152653_bib0215","series-title":"(Scientific Committee on Emerging and Newly-identified Health Risks). Opinion on the Safety of Medical Devices Containing DEHP-plasticized PVC or Other Plasticizers on Neonates and Other Groups Possibly at Risk","author":"SCENIHR","year":"2015"},{"key":"10.1016\/j.tox.2020.152653_bib0220","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1289\/ehp.1104016","article-title":"Effects of di(2-ethylhexyl) phthalate (DEHP) on female fertility and adipogenesis in C3H\/N mice","volume":"120","author":"Schmidt","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.tox.2020.152653_bib0225","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1080\/01926230252824761","article-title":"Qualitative and quantitative analysis of nonneoplastic lesions in toxicology studies","volume":"30","author":"Shackelford","year":"2002","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.tox.2020.152653_bib0230","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/j.cmet.2016.04.011","article-title":"Adiponectin, leptin, and fatty acids in the maintenance of metabolic homeostasis through adipose tissue crosstalk","volume":"23","author":"Stern","year":"2016","journal-title":"Cell Metab."},{"key":"10.1016\/j.tox.2020.152653_bib0235","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.steroids.2011.10.013","article-title":"Tissue physiology and pathology of aromatase","volume":"77","author":"Stocco","year":"2012","journal-title":"Steroids"},{"key":"10.1016\/j.tox.2020.152653_bib0240","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/j.jnutbio.2015.05.012","article-title":"In utero growth restriction and catch-up adipogenesis after developmental di (2-ethylhexyl) phthalate exposure cause glucose intolerance in adult male rats following a high-fat dietary challenge","volume":"26","author":"Strakovsky","year":"2015","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.tox.2020.152653_bib0245","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1507\/endocrj.EJ17-0272","article-title":"Effect of Di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-thyroid axis in adolescent rat","volume":"65","author":"Sun","year":"2018","journal-title":"Endocr. J."},{"key":"10.1016\/j.tox.2020.152653_bib0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2020.109428","article-title":"Biomonitoring of Bis(2-ethylhexyl)phthalate (DEHP) in Italian children and adolescents: data from LIFE PERSUADED project","volume":"185","author":"Tait","year":"2020","journal-title":"Environ. Res."},{"key":"10.1016\/j.tox.2020.152653_bib0255","article-title":"Juvenile toxicity rodent model to study toxicological effects of Bisphenol A (BPA) at dose levels derived from Italian children biomonitoring study","author":"Tassinari","year":"2019","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.tox.2020.152653_bib0260","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1365-2796.2004.01426.x","article-title":"Adiponectin--journey from an adipocyte secretory protein to biomarker of the metabolic syndrome","volume":"257","author":"Trujillo","year":"2005","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.tox.2020.152653_bib0265","doi-asserted-by":"crossref","DOI":"10.3390\/toxics7020021","article-title":"A review of biomonitoring of phthalate exposures","volume":"7","author":"Wang","year":"2019","journal-title":"Toxics"},{"key":"10.1016\/j.tox.2020.152653_bib0270","series-title":"State of the Science of Endocrine Disrupting Chemicals - 2012. An Assessment of the State of the Science of Endocrine Disruptors Prepared by a Group of Experts for the United Nations Environment Programme (UNEP) and WHO","author":"WHO\/UNEP","year":"2016"},{"key":"10.1016\/j.tox.2020.152653_bib0275","series-title":"Multigeneration Reproduction Toxicity Study in Rats (unaudited Draft): Diethylhexylphthalate: Multigenerational Reproductive Assessment by Continuous Breeding When Administered to Sprague-Dawley Rats in the Diet","author":"Wolfe","year":"2003"},{"key":"10.1016\/j.tox.2020.152653_bib0280","doi-asserted-by":"crossref","first-page":"40153","DOI":"10.1038\/srep40153","article-title":"Di2-ethylhexyl phthalate disrupts thyroid hormone homeostasis through activating the Ras\/Akt\/TRHr pathway and inducing hepatic enzymes","volume":"7","author":"Ye","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tox.2020.152653_bib0285","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1002\/em.22037","article-title":"Di(2-ethylhexyl)phthalate: adverse effects on folliculogenesis that cannot be neglected","volume":"57","author":"Zhang","year":"2016","journal-title":"Environ. Mol. Mutagen."}],"container-title":["Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X20302924?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X20302924?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T23:44:30Z","timestamp":1759535070000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300483X20302924"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":57,"alternative-id":["S0300483X20302924"],"URL":"https:\/\/doi.org\/10.1016\/j.tox.2020.152653","relation":{},"ISSN":["0300-483X"],"issn-type":[{"value":"0300-483X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Metabolic, reproductive and thyroid effects of bis(2-ethylhexyl) phthalate (DEHP) orally administered to male and female juvenile rats at dose levels derived from children biomonitoring study","name":"articletitle","label":"Article Title"},{"value":"Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tox.2020.152653","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"152653"}}