{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T13:08:59Z","timestamp":1793106539223,"version":"4.5.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004704","name":"National Research Council of Thailand","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004704","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002842","name":"Chiang Mai University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002842","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004192","name":"National Science and Technology Development Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004192","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.tox.2023.153553","type":"journal-article","created":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T11:23:54Z","timestamp":1684754634000},"page":"153553","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"special_numbering":"C","title":["Chronic D-galactose administration induces natural aging characteristics, in rat\u2019s brain and heart"],"prefix":"10.1016","volume":"492","author":[{"given":"Patcharapong","family":"Pantiya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanisa","family":"Thonusin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Ongnok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Titikorn","family":"Chunchai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aphisek","family":"Kongkaew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wichwara","family":"Nawara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Busarin","family":"Arunsak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nipon","family":"Chattipakorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siriporn C","family":"Chattipakorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tox.2023.153553_bib1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/arch.21176","article-title":"Effect of tempol on redox homeostasis and stress tolerance in mimetically aged Drosophila","volume":"87","author":"Aksu","year":"2014","journal-title":"Arch. Insect Biochem Physiol."},{"key":"10.1016\/j.tox.2023.153553_bib2","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1365-2567.2009.03225.x","article-title":"Inflammation in neurodegenerative diseases","volume":"129","author":"Amor","year":"2010","journal-title":"Immunology"},{"key":"10.1016\/j.tox.2023.153553_bib3","doi-asserted-by":"crossref","first-page":"9189","DOI":"10.1111\/jcmm.15556","article-title":"PCSK9 inhibitor and atorvastatin reduce cardiac impairment in ovariectomized prediabetic rats via improved mitochondrial function and Ca(2+) regulation","volume":"24","author":"Amput","year":"2020","journal-title":"J. Cell Mol. Med"},{"key":"10.1016\/j.tox.2023.153553_bib4","doi-asserted-by":"crossref","DOI":"10.15420\/ecr.2020.50","article-title":"Inflammation and cardiovascular disease: the future","volume":"16","author":"Arnold","year":"2021","journal-title":"Eur. Cardiol."},{"key":"10.1016\/j.tox.2023.153553_bib5","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s10522-022-09973-y","article-title":"Mitochondria-targeted senotherapeutic interventions","volume":"23","author":"Atayik","year":"2022","journal-title":"Biogerontology"},{"key":"10.1016\/j.tox.2023.153553_bib6","doi-asserted-by":"crossref","first-page":"e29","DOI":"10.1002\/bjs.10053","article-title":"Molecular and biological hallmarks of ageing","volume":"103","author":"Aunan","year":"2016","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.tox.2023.153553_bib7","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1111\/jcmm.13472","article-title":"Effects of d-galactose-induced ageing on the heart and its potential interventions","volume":"22","author":"Bo-Htay","year":"2018","journal-title":"J. Cell Mol. Med"},{"key":"10.1016\/j.tox.2023.153553_bib8","doi-asserted-by":"crossref","first-page":"10955","DOI":"10.18632\/aging.202970","article-title":"Hyperbaric oxygen therapy effectively alleviates D-galactose-induced-age-related cardiac dysfunction via attenuating mitochondrial dysfunction in pre-diabetic rats","volume":"13","author":"Bo-Htay","year":"2021","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.tox.2023.153553_bib9","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1038\/nrm2233","article-title":"Cellular senescence: when bad things happen to good cells","volume":"8","author":"Campisi","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.tox.2023.153553_bib10","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/nn1048","article-title":"Becoming a new neuron in the adult olfactory bulb","volume":"6","author":"Carleton","year":"2003","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.tox.2023.153553_bib11","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.exger.2014.05.017","article-title":"Oxidation scrutiny in persuaded aging and chronological aging at systemic redox homeostasis level","volume":"57","author":"Cebe","year":"2014","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.tox.2023.153553_bib12","doi-asserted-by":"crossref","first-page":"9728","DOI":"10.1007\/s11357-014-9728-y","article-title":"A comprehensive study of myocardial redox homeostasis in naturally and mimetically aged rats","volume":"36","author":"Cebe","year":"2014","journal-title":"Age (Dordr. )"},{"key":"10.1016\/j.tox.2023.153553_bib13","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1089\/jmf.2013.2830","article-title":"D-galactose induces a mitochondrial complex I deficiency in mouse skeletal muscle: potential benefits of nutrient combination in ameliorating muscle impairment","volume":"17","author":"Chang","year":"2014","journal-title":"J. Med Food"},{"key":"10.1016\/j.tox.2023.153553_bib14","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.2147\/JIR.S275595","article-title":"Reactive oxygen species: drivers of physiological and pathological processes","volume":"13","author":"Checa","year":"2020","journal-title":"J. Inflamm. Res"},{"key":"10.1016\/j.tox.2023.153553_bib15","doi-asserted-by":"crossref","first-page":"3445","DOI":"10.18632\/aging.101989","article-title":"N-acetyl cysteine, inulin and the two as a combined therapy ameliorate cognitive decline in testosterone-deprived rats","volume":"11","author":"Chunchai","year":"2019","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.tox.2023.153553_bib16","doi-asserted-by":"crossref","first-page":"367","DOI":"10.14336\/AD.2018.0324","article-title":"Redefining chronic inflammation in aging and age-related diseases: proposal of the senoinflammation concept","volume":"10","author":"Chung","year":"2019","journal-title":"Aging Dis."},{"key":"10.1016\/j.tox.2023.153553_bib17","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1126\/science.1173215","article-title":"A functional role for adult hippocampal neurogenesis in spatial pattern separation","volume":"325","author":"Clelland","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.tox.2023.153553_bib18","article-title":"Oxidative stress, mitochondrial dysfunction, and aging","volume":"2012","author":"Cui","year":"2012","journal-title":"J. Signal Transduct."},{"key":"10.1016\/j.tox.2023.153553_bib19","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1038\/nrn2822","article-title":"New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?","volume":"11","author":"Deng","year":"2010","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.tox.2023.153553_bib20","doi-asserted-by":"crossref","DOI":"10.3791\/58593","article-title":"Novel object recognition and object location behavioral testing in mice on a budget","author":"Denninger","year":"2018","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.tox.2023.153553_bib21","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1093\/gerona\/glv070","article-title":"Reconsidering the role of mitochondria in aging","volume":"70","author":"Gonzalez-Freire","year":"2015","journal-title":"J. Gerontol. A Biol. Sci. Med Sci."},{"key":"10.1016\/j.tox.2023.153553_bib22","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.biochi.2015.10.013","article-title":"Nutrient sensing and utilization: getting to the heart of metabolic flexibility","volume":"124","author":"Griffin","year":"2016","journal-title":"Biochimie"},{"key":"10.1016\/j.tox.2023.153553_bib23","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s10522-020-09859-x","article-title":"D-Galactose-induced oxidative stress and mitochondrial dysfunction in the cochlear basilar membrane: an in vitro aging model","volume":"21","author":"Guo","year":"2020","journal-title":"Biogerontology"},{"key":"10.1016\/j.tox.2023.153553_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2022.120406","article-title":"Hyperbaric oxygen therapy improves age induced bone dyshomeostasis in non-obese and obese conditions","volume":"295","author":"Imerb","year":"2022","journal-title":"Life Sci."},{"key":"10.1016\/j.tox.2023.153553_bib25","first-page":"21","article-title":"Effects of Ketone bodies on brain metabolism and function in neurodegenerative diseases","author":"Jensen","year":"2020","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.tox.2023.153553_bib26","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1161\/01.RES.86.12.1193","article-title":"Gap junctions in cardiovascular disease","volume":"86","author":"Jongsma","year":"2000","journal-title":"Circ. Res"},{"key":"10.1016\/j.tox.2023.153553_bib27","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s41232-020-00122-x","article-title":"Current understanding of adult neurogenesis in the mammalian brain: how does adult neurogenesis decrease with age?","volume":"40","author":"Kase","year":"2020","journal-title":"Inflamm. Regen."},{"key":"10.1016\/j.tox.2023.153553_bib28","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1161\/CIRCRESAHA.113.302095","article-title":"Cardiac metabolism and its interactions with contraction, growth, and survival of cardiomyocytes","volume":"113","author":"Kolwicz","year":"2013","journal-title":"Circ. Res"},{"key":"10.1016\/j.tox.2023.153553_bib29","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0022-0736(05)80272-9","article-title":"Power spectral analysis of heart rate variability as a new method for assessing autonomic activity in the rat","volume":"27","author":"Kuwahara","year":"1994","journal-title":"J. Electro"},{"key":"10.1016\/j.tox.2023.153553_bib30","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/978-0-387-85998-9_45","article-title":"Ketones suppress brain glucose consumption","volume":"645","author":"LaManna","year":"2009","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.tox.2023.153553_bib31","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1474-9726.2006.00199.x","article-title":"Senescence-associated beta-galactosidase is lysosomal beta-galactosidase","volume":"5","author":"Lee","year":"2006","journal-title":"Aging Cell"},{"key":"10.1016\/j.tox.2023.153553_bib32","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s10522-021-09910-5","article-title":"Aging and age-related diseases: from mechanisms to therapeutic strategies","volume":"22","author":"Li","year":"2021","journal-title":"Biogerontology"},{"key":"10.1016\/j.tox.2023.153553_bib33","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.cell.2013.05.039","article-title":"The hallmarks of aging","volume":"153","author":"L\u00f3pez-Ot\u00edn","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.tox.2023.153553_bib34","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.tins.2013.07.001","article-title":"Sugar for the brain: the role of glucose in physiological and pathological brain function","volume":"36","author":"Mergenthaler","year":"2013","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.tox.2023.153553_bib35","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.cger.2012.08.005","article-title":"Mechanisms of arrhythmias and conduction disorders in older adults","volume":"28","author":"Mirza","year":"2012","journal-title":"Clin. Geriatr. Med"},{"key":"10.1016\/j.tox.2023.153553_bib36","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.stem.2018.01.003","article-title":". Adult neurogenesis is sustained by symmetric self-renewal and differentiation","volume":"22","author":"Obernier","year":"2018","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.tox.2023.153553_bib37","doi-asserted-by":"crossref","DOI":"10.1111\/febs.16474","article-title":"Modulation of mitochondrial dynamics rescues cognitive function in rats with 'doxorubicin-induced chemobrain' via mitigation of mitochondrial dysfunction and neuroinflammation","author":"Ongnok","year":"2022","journal-title":"Febs J."},{"key":"10.1016\/j.tox.2023.153553_bib38","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1113\/expphysiol.2012.070433","article-title":"Mechanisms responsible for beneficial and adverse effects of rosiglitazone in a rat model of acute cardiac ischaemia-reperfusion","volume":"98","author":"Palee","year":"2013","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.tox.2023.153553_bib39","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1080\/15384101.2017.1377500","article-title":"The anti-aging promise of p21","volume":"16","author":"Papismadov","year":"2017","journal-title":"Cell Cycle"},{"key":"10.1016\/j.tox.2023.153553_bib40","article-title":"Cardiac regeneration: new insights into the frontier of ischemic heart failure therapy","volume":"8","author":"Riching","year":"2020","journal-title":"Front Bioeng. Biotechnol."},{"key":"10.1016\/j.tox.2023.153553_bib41","article-title":"Cardiovascular risks associated with gender and aging","volume":"6","author":"Rodgers","year":"2019","journal-title":"J. Cardiovasc Dev. Dis."},{"key":"10.1016\/j.tox.2023.153553_bib42","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/sj.ejhg.5200793","article-title":"Succinate dehydrogenase and human diseases: new insights into a well-known enzyme","volume":"10","author":"Rustin","year":"2002","journal-title":"Eur. J. Hum. Genet"},{"key":"10.1016\/j.tox.2023.153553_bib43","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1161\/CIRCRESAHA.116.306842","article-title":"Lipid use and misuse by the heart","volume":"118","author":"Schulze","year":"2016","journal-title":"Circ. Res"},{"key":"10.1016\/j.tox.2023.153553_bib44","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.cardiores.2003.12.007","article-title":"Gap junction alterations in human cardiac disease","volume":"62","author":"Severs","year":"2004","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.tox.2023.153553_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.mad.2021.111465","article-title":"Hyperbaric oxygen therapy restores cognitive function and hippocampal pathologies in both aging and aging-obese rats","volume":"195","author":"Shwe","year":"2021","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.tox.2023.153553_bib46","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.exger.2017.10.029","article-title":"Role of D-galactose-induced brain aging and its potential used for therapeutic interventions","volume":"101","author":"Shwe","year":"2018","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.tox.2023.153553_bib47","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/nature10287","article-title":"Adult hippocampal neurogenesis buffers stress responses and depressive behaviour","volume":"476","author":"Snyder","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.tox.2023.153553_bib48","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.semcdb.2021.02.006","article-title":"Aging: all roads lead to mitochondria","volume":"116","author":"Son","year":"2021","journal-title":"Semin Cell Dev. Biol."},{"key":"10.1016\/j.tox.2023.153553_bib49","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20163879","article-title":"Inflammation and cardiovascular diseases: the most recent findings","volume":"20","author":"Sorriento","year":"2019","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.tox.2023.153553_bib50","doi-asserted-by":"crossref","first-page":"281","DOI":"10.33549\/physiolres.932019","article-title":"Effects of aging on activities of mitochondrial electron transport chain complexes and oxidative damage in rat heart","volume":"60","author":"Tatarkov\u00e1","year":"2011","journal-title":"Physiol. Res"},{"key":"10.1016\/j.tox.2023.153553_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2019.114741","article-title":"The comparative effects of high dose atorvastatin and proprotein convertase subtilisin\/kexin type 9 inhibitor on the mitochondria of oxidative muscle fibers in obese-insulin resistant female rats","volume":"382","author":"Thonusin","year":"2019","journal-title":"Toxicol. Appl. Pharm."},{"key":"10.1016\/j.tox.2023.153553_bib52","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.chroma.2017.09.023","article-title":"Evaluation of intensity drift correction strategies using MetaboDrift, a normalization tool for multi-batch metabolomics data","volume":"1523","author":"Thonusin","year":"2017","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.tox.2023.153553_bib53","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s10020-022-00458-9","article-title":"Effectiveness of high cardiorespiratory fitness in cardiometabolic protection in prediabetic rats","volume":"28","author":"Thonusin","year":"2022","journal-title":"Mol. Med"},{"key":"10.1016\/j.tox.2023.153553_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuint.2021.104982","article-title":"The effect of aged microglia on synaptic impairment and its relevance in neurodegenerative diseases","volume":"144","author":"Trivi\u00f1o","year":"2021","journal-title":"Neurochem Int"},{"key":"10.1016\/j.tox.2023.153553_bib55","first-page":"11","article-title":"The role of antioxidants in the interplay between oxidative stress and senescence","author":"Varesi","year":"2022","journal-title":"Antioxid. (Basel)"},{"key":"10.1016\/j.tox.2023.153553_bib56","doi-asserted-by":"crossref","DOI":"10.1002\/0471142301.ns0831s69","article-title":"Examining object location and object recognition memory in mice","volume":"69","author":"Vogel-Ciernia","year":"2014","journal-title":"Curr. Protoc. Neurosci."},{"key":"10.1016\/j.tox.2023.153553_bib57","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.nlm.2008.01.010","article-title":"Purple sweet potato color repairs d-galactose-induced spatial learning and memory impairment by regulating the expression of synaptic proteins","volume":"90","author":"Wu","year":"2008","journal-title":"Neurobiol. Learn Mem."},{"key":"10.1016\/j.tox.2023.153553_bib58","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1111\/j.1742-7843.2011.00756.x","article-title":"Protein and DNA oxidation in different anatomic regions of rat brain in a mimetic ageing model","volume":"109","author":"Yanar","year":"2011","journal-title":"Basic Clin. Pharm. Toxicol."}],"container-title":["Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X23001397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X23001397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T23:57:41Z","timestamp":1759535861000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300483X23001397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":58,"alternative-id":["S0300483X23001397"],"URL":"https:\/\/doi.org\/10.1016\/j.tox.2023.153553","relation":{},"ISSN":["0300-483X"],"issn-type":[{"value":"0300-483X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chronic D-galactose administration induces natural aging characteristics, in rat\u2019s brain and heart","name":"articletitle","label":"Article Title"},{"value":"Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tox.2023.153553","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"153553"}}