{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T23:04:25Z","timestamp":1788995065461,"version":"build-2803163510"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81872623"],"award-info":[{"award-number":["81872623"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005047","name":"Liaoning Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["2023-MS-269"],"award-info":[{"award-number":["2023-MS-269"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.tox.2024.153863","type":"journal-article","created":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T13:32:26Z","timestamp":1718285546000},"page":"153863","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Curcumin inhibits PAT-induced renal ferroptosis via the p62\/Keap1\/Nrf2 signalling pathway"],"prefix":"10.1016","volume":"506","author":[{"given":"Jianan","family":"Zhai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengguo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhifang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiance","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ningning","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofeng","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyuan","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaopeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tox.2024.153863_bib1","doi-asserted-by":"crossref","first-page":"466","DOI":"10.3389\/fnins.2018.00466","article-title":"Targeting Nrf2 to suppress ferroptosis and mitochondrial dysfunction in neurodegeneration","volume":"12","author":"Abdalkader","year":"2018","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.tox.2024.153863_bib2","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1080\/1061186X.2020.1722136","article-title":"Thymoquinone and curcumin combination protects cisplatin-induced kidney injury, nephrotoxicity by attenuating NF\u03baB, KIM-1 and ameliorating Nrf2\/HO-1 signalling.","volume":"28","author":"Al Fayi","year":"2020","journal-title":"J. Drug Target."},{"key":"10.1016\/j.tox.2024.153863_bib3","doi-asserted-by":"crossref","first-page":"R204","DOI":"10.1186\/cc2872","article-title":"Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the second international consensus conference of the acute dialysis quality initiative (ADQI) Group","volume":"8","author":"Bellomo","year":"2004","journal-title":"Crit. Care"},{"key":"10.1016\/j.tox.2024.153863_bib4","doi-asserted-by":"crossref","first-page":"9799","DOI":"10.1007\/s11356-016-6195-2","article-title":"Crocin protects the liver and kidney from patulin-induced apoptosis in vivo","volume":"23","author":"Boussabbeh","year":"2016","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.tox.2024.153863_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154306","article-title":"Role of curcumin in the treatment of acute kidney injury: research challenges and opportunities","volume":"104","author":"Cai","year":"2022","journal-title":"Phytomedicine: Int. J. Phytother. Phytopharm."},{"key":"10.1016\/j.tox.2024.153863_bib6","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.redox.2016.05.003","article-title":"Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration","volume":"9","author":"Carlson","year":"2016","journal-title":"Redox Biol."},{"key":"10.1016\/j.tox.2024.153863_bib7","first-page":"141","article-title":"Nanodrugs alleviate acute kidney injury: Manipulate RONS at kidney","volume":"22","author":"Chen","year":"2023","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.tox.2024.153863_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2020.111867","article-title":"Patulin induces pyroptosis through the autophagic-inflammasomal pathway in liver","volume":"147","author":"Chu","year":"2021","journal-title":"Food Chem. Toxicol.: Int. J. Publ. Br. Ind. Biol. Res. Assoc."},{"key":"10.1016\/j.tox.2024.153863_bib9","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/s41573-018-0008-x","article-title":"Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases","volume":"18","author":"Cuadrado","year":"2019","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.tox.2024.153863_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101453","article-title":"Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage","volume":"32","author":"Deng","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.tox.2024.153863_bib11","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22147534","article-title":"The effect of liposomal curcumin as an anti-inflammatory strategy on lipopolysaccharide e from porphyromonas gingivalis treated endothelial committed neural crest derived stem cells: morphological and molecular mechanisms","volume":"22","author":"Diomede","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tox.2024.153863_bib12","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: an iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.tox.2024.153863_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2019.101107","article-title":"NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis","volume":"23","author":"Dodson","year":"2019","journal-title":"Redox Biol."},{"key":"10.1016\/j.tox.2024.153863_bib14","doi-asserted-by":"crossref","DOI":"10.3390\/toxins12040227","article-title":"Inflammation and premature ageing in chronic kidney disease","volume":"12","author":"Ebert","year":"2020","journal-title":"Toxins"},{"key":"10.1016\/j.tox.2024.153863_bib15","doi-asserted-by":"crossref","first-page":"614","DOI":"10.4161\/auto.6.5.12189","article-title":"Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy","volume":"6","author":"Fan","year":"2010","journal-title":"Autophagy"},{"key":"10.1016\/j.tox.2024.153863_bib16","article-title":"Ferroptosis and Acute Kidney Injury (AKI): Molecular Mechanisms and Therapeutic Potentials","volume":"13","author":"Feng","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.tox.2024.153863_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2023.121996","article-title":"Podocin, mTOR, and CHOP dysregulation contributes to nephrotoxicity induced of lipopolysaccharide\/diclofenac combination in rats: Curcumin and silymarin could afford protective effect","volume":"330","author":"Hasan","year":"2023","journal-title":"Life Sci."},{"key":"10.1016\/j.tox.2024.153863_bib18","doi-asserted-by":"crossref","DOI":"10.3390\/foods6100092","article-title":"Curcumin: A Review of Its Effects on Human Health","volume":"6","author":"Hewlings","year":"2017","journal-title":"Foods"},{"key":"10.1016\/j.tox.2024.153863_bib19","doi-asserted-by":"crossref","first-page":"6213","DOI":"10.1021\/acs.jafc.1c08349","article-title":"Patulin Induces Acute Kidney Injury in Mice through Autophagy-Ferroptosis Pathway","volume":"70","author":"Hou","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.tox.2024.153863_bib20","article-title":"Effects and molecular mechanism of pachymic acid on ferroptosis in renal ischemia reperfusion injury","volume":"23","author":"Jiang","year":"2021","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.tox.2024.153863_bib21","doi-asserted-by":"crossref","first-page":"426","DOI":"10.4161\/auto.19258","article-title":"Autophagic proteins: new facets of the oxygen paradox","volume":"8","author":"Jin","year":"2012","journal-title":"Autophagy"},{"key":"10.1016\/j.tox.2024.153863_bib22","doi-asserted-by":"crossref","first-page":"279","DOI":"10.4161\/auto.7.3.14487","article-title":"Selective autophagy mediated by autophagic adapter proteins","volume":"7","author":"Johansen","year":"2011","journal-title":"Autophagy"},{"key":"10.1016\/j.tox.2024.153863_bib23","article-title":"Curcumin suppresses RANKL-induced osteoclast precursor autophagy in osteoclastogenesis by inhibiting RANK signaling and downstream JNK-BCL2-Beclin1 pathway","author":"Ke","year":"2023","journal-title":"Biomed. J."},{"key":"10.1016\/j.tox.2024.153863_bib24","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.fct.2018.02.007","article-title":"Curcumin ameliorates cadmium-induced nephrotoxicity in Sprague-Dawley rats","volume":"114","author":"Kim","year":"2018","journal-title":"Food Chem. Toxicol.: Int. J. Publ. Br. Ind. Biol. Res. Assoc."},{"key":"10.1016\/j.tox.2024.153863_bib25","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/j.1365-2443.2010.01433.x","article-title":"Selective autophagy regulates various cellular functions","volume":"15","author":"Komatsu","year":"2010","journal-title":"Genes Cells.: devoted Mol. Cell. Mech."},{"key":"10.1016\/j.tox.2024.153863_bib26","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1038\/s41419-021-04227-0","article-title":"Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury","volume":"12","author":"Kong","year":"2021","journal-title":"Cell death Dis."},{"key":"10.1016\/j.tox.2024.153863_bib27","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.molcel.2010.09.023","article-title":"Autophagy and the integrated stress response","volume":"40","author":"Kroemer","year":"2010","journal-title":"Mol. Cell"},{"key":"10.1016\/j.tox.2024.153863_bib28","doi-asserted-by":"crossref","first-page":"3275","DOI":"10.1128\/MCB.00248-10","article-title":"A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62","volume":"30","author":"Lau","year":"2010","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.tox.2024.153863_bib29","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/ki.2013.153","article-title":"Raising awareness of acute kidney injury: a global perspective of a silent killer","volume":"84","author":"Lewington","year":"2013","journal-title":"Kidney Int."},{"key":"10.1016\/j.tox.2024.153863_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.154729","article-title":"Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice","volume":"113","author":"Liu","year":"2023","journal-title":"Phytomedicine: Int. J. Phytother. Phytopharm."},{"key":"10.1016\/j.tox.2024.153863_bib31","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.bbadis.2014.05.010","article-title":"The role of the autophagy in myocardial ischemia\/reperfusion injury","volume":"1852","author":"Ma","year":"2015","journal-title":"Biochim. Et. Biophys. Acta"},{"key":"10.1016\/j.tox.2024.153863_bib32","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1016\/S0140-6736(15)60126-X","article-title":"International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology","volume":"385","author":"Mehta","year":"2015","journal-title":"Lancet (Lond., Engl. )"},{"key":"10.1016\/j.tox.2024.153863_bib33","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1007\/s00210-018-1514-4","article-title":". Protective effects of amifostine, curcumin, and melatonin against cisplatin-induced acute kidney injury","volume":"391","author":"Mercantepe","year":"2018","journal-title":"Naunyn-Schmiede 'S. Arch. Pharmacol."},{"key":"10.1016\/j.tox.2024.153863_bib34","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1080\/15548627.2017.1345411","article-title":"N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1\/p62-bodies and activation of NFE2L2","volume":"13","author":"Mildenberger","year":"2017","journal-title":"Autophagy"},{"key":"10.1016\/j.tox.2024.153863_bib35","article-title":"Serum and urine metabolomics analysis reveals the role of altered metabolites in patulin-induced nephrotoxicity","volume":"156","author":"Pal","year":"2022","journal-title":"Food Res. Int. (Ott., Ont. )"},{"key":"10.1016\/j.tox.2024.153863_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2021.115819","article-title":"TGF-\u03b2\/Smad signaling pathway plays a crucial role in patulin-induced pro-fibrotic changes in rat kidney via modulation of slug and snail expression.","volume":"434","author":"Pal","year":"2022","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.tox.2024.153863_bib37","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/NEN.0000000000000179","article-title":"Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with a\u03b2 and tau pathology","volume":"74","author":"Perez","year":"2015","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.tox.2024.153863_bib38","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/ckj\/sfw134","article-title":"International Society of Nephrology's 0by25 initiative (zero preventable deaths from acute kidney injury by 2025): focus on diagnosis of acute kidney injury in low-income countries","volume":"11","author":"Raimann","year":"2018","journal-title":"Clin. Kidney J."},{"key":"10.1016\/j.tox.2024.153863_bib39","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1074\/jbc.M114.590281","article-title":"p62 plays a protective role in the autophagic degradation of polyglutamine protein oligomers in polyglutamine disease model flies","volume":"290","author":"Saitoh","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tox.2024.153863_bib40","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.fct.2019.04.036","article-title":"The characteristics, occurrence, and toxicological effects of patulin","volume":"129","author":"Saleh","year":"2019","journal-title":"Food Chem. Toxicol.: Int. J. Publ. Br. Ind. Biol. Res. Assoc."},{"key":"10.1016\/j.tox.2024.153863_bib41","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1002\/jcb.30487","article-title":"Curcumin inhibits the activity and induces apoptosis of activated hepatic stellate cell by suppressing autophagy","volume":"124","author":"Shu","year":"2023","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.tox.2024.153863_bib42","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.phrs.2018.06.013","article-title":"Canonical and non-canonical mechanisms of Nrf2 activation","volume":"134","author":"Silva-Islas","year":"2018","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.tox.2024.153863_bib43","doi-asserted-by":"crossref","first-page":"5540","DOI":"10.1080\/10408398.2021.1887077","article-title":"Patulin and Trichothecene: characteristics, occurrence, toxic effects and detection capabilities via clinical, analytical and nanostructured electrochemical sensing\/biosensing assays in foodstuffs","volume":"62","author":"Sohrabi","year":"2022","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.tox.2024.153863_bib44","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1002\/ptr.6054","article-title":"Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: Review","volume":"32","author":"Soleimani","year":"2018","journal-title":"Phytother. Res.: PTR"},{"key":"10.1016\/j.tox.2024.153863_bib45","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.fct.2014.06.009","article-title":"Hepatotoxicity and genotoxicity of patulin in mice, and its modulation by green tea polyphenols administration","volume":"71","author":"Song","year":"2014","journal-title":"Food Chem. Toxicol.: Int. J. Publ. Br. Ind. Biol. Res. Assoc."},{"key":"10.1016\/j.tox.2024.153863_bib46","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/hep.28251","article-title":"Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells","volume":"63","author":"Sun","year":"2016","journal-title":"Hepatol. (Baltim., Md. )"},{"key":"10.1016\/j.tox.2024.153863_bib47","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.163161","article-title":"Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells","volume":"7","author":"Thomas","year":"2022","journal-title":"JCI Insight"},{"key":"10.1016\/j.tox.2024.153863_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2023.175516","article-title":"Astragaloside IV mitigates cerebral ischaemia-reperfusion injury via inhibition of P62\/Keap1\/Nrf2 pathway-mediated ferroptosis","volume":"944","author":"Wang","year":"2023","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.tox.2024.153863_bib49","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.toxicon.2020.05.006","article-title":"Progress in the distribution, toxicity, control, and detoxification of patulin: A review","volume":"184","author":"Wei","year":"2020","journal-title":"Toxicon"},{"key":"10.1016\/j.tox.2024.153863_bib50","first-page":"282","article-title":"Nanostructured polyvinylpyrrolidone-curcumin conjugates allowed for kidney-targeted treatment of cisplatin induced acute kidney injury","volume":"19","author":"Wei","year":"2023","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.tox.2024.153863_bib51","article-title":"Curcumin Attenuates Both Acute and Chronic Immune Nephritis","volume":"21","author":"Wu","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tox.2024.153863_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2023.113609","article-title":"Inhibition of ATF4-mediated elevation of both autophagy and AKT\/mTOR was involved in antitumorigenic activity of curcumin","volume":"173","author":"Yang","year":"2023","journal-title":"Food Chem. Toxicol.: Int. J. Publ. Br. Ind. Biol. Res. Assoc."},{"key":"10.1016\/j.tox.2024.153863_bib53","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.382","article-title":"Dimethyl fumarate prevents ferroptosis to attenuate acute kidney injury by acting on NRF2","volume":"11","author":"Yang","year":"2021","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.tox.2024.153863_bib54","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.trsl.2015.06.004","article-title":"Marked protection against acute renal and hepatic injury after nitrited myoglobin + tin protoporphyrin administration","volume":"166","author":"Zager","year":"2015","journal-title":"Transl. Res"},{"key":"10.1016\/j.tox.2024.153863_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2020.101207","article-title":"Novel target for treating Alzheimer's Diseases: Crosstalk between the Nrf2 pathway and autophagy","volume":"65","author":"Zhang","year":"2021","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.tox.2024.153863_bib56","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1002\/ptr.7370","article-title":"Urolithin A alleviates acute kidney injury induced by renal ischemia reperfusion through the p62-Keap1-Nrf2 signaling pathway","volume":"36","author":"Zhang","year":"2022","journal-title":"Phytother. Res.: PTR"},{"key":"10.1016\/j.tox.2024.153863_bib57","doi-asserted-by":"crossref","first-page":"9671","DOI":"10.1021\/acs.jafc.1c03751","article-title":"Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway","volume":"69","author":"Zhao","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.tox.2024.153863_bib58","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.22630","article-title":"Curcumin alleviates acute kidney injury in a dry-heat environment by reducing oxidative stress and inflammation in a rat model","volume":"35","author":"Zhao","year":"2021","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.tox.2024.153863_bib59","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1080\/15384101.2020.1784599","article-title":"Curcumin attenuates inflammation and cell apoptosis through regulating NF-\u03baB and JAK2\/STAT3 signaling pathway against acute kidney injury.","volume":"19","author":"Zhu","year":"2020","journal-title":"Cell Cycle (Georget., Tex. )"}],"container-title":["Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X24001446?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300483X24001446?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T14:38:54Z","timestamp":1721486334000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300483X24001446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":59,"alternative-id":["S0300483X24001446"],"URL":"https:\/\/doi.org\/10.1016\/j.tox.2024.153863","relation":{},"ISSN":["0300-483X"],"issn-type":[{"value":"0300-483X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Curcumin inhibits PAT-induced renal ferroptosis via the p62\/Keap1\/Nrf2 signalling pathway","name":"articletitle","label":"Article Title"},{"value":"Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tox.2024.153863","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"153863"}}