{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T21:09:24Z","timestamp":1648933764876},"reference-count":51,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicon"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1016\/j.toxicon.2005.08.016","type":"journal-article","created":{"date-parts":[[2005,11,30]],"date-time":"2005-11-30T19:57:46Z","timestamp":1133380666000},"page":"907-917","source":"Crossref","is-referenced-by-count":7,"title":["Purification, primary structures and evolution of coagulant proteases from Deinagkistrodon actus venom"],"prefix":"10.1016","volume":"46","author":[{"given":"Nikolai N.","family":"Nikandrov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanobu","family":"Deshimaru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayako","family":"Tani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahito","family":"Chijiwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Shibata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Chun","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuyuki","family":"Fukumaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsumi","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motonori","family":"Ohno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.toxicon.2005.08.016_bib1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1042\/bj2940387","article-title":"Molecular cloning and sequence analysis of the cDNA for ancrod, a thrombin-like enzyme from venom of Callaselasma rhodostoma","volume":"294","author":"Au","year":"1993","journal-title":"Biochem. J."},{"key":"10.1016\/j.toxicon.2005.08.016_bib2","first-page":"1","article-title":"Classification of peptidases","volume":"vol. 244","author":"Barrett","year":"1994"},{"key":"10.1016\/j.toxicon.2005.08.016_bib3","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0378-4347(00)85133-6","article-title":"Rapid analysis of amino acids using pre-column derivatization","volume":"336","author":"Bidlingmeyer","year":"1984","journal-title":"J. Chromatogr."},{"key":"10.1016\/j.toxicon.2005.08.016_bib4","series-title":"Thrombin: Structure and Function","first-page":"3","article-title":"X-Ray crystal structure of human \u03b1-thrombin and of the human thrombin-hirudin complex","author":"Bode","year":"1992"},{"key":"10.1016\/j.toxicon.2005.08.016_bib5","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0014-5793(92)80559-Y","article-title":"Amino acid sequence determination of ancrod, the thrombin-like \u03b1-fibrinogenase from venom of Agkistrodon rhodostoma","volume":"297","author":"Burkhart","year":"1992","journal-title":"FEBS Lett."},{"key":"10.1016\/j.toxicon.2005.08.016_bib6","doi-asserted-by":"crossref","first-page":"5294","DOI":"10.1021\/bi00591a005","article-title":"Isolation of biologically active ribonucleic acid from sources enriched by ribonuclease","volume":"18","author":"Chirgwin","year":"1979","journal-title":"Biochemistry"},{"key":"10.1016\/j.toxicon.2005.08.016_bib7","series-title":"Atlas of protein sequence and structure","author":"Dayhoff","year":"1972"},{"key":"10.1016\/j.toxicon.2005.08.016_bib8","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0014-5793(96)01144-1","article-title":"Accelerated evolution of crotalinae snake venom gland serine protease","volume":"397","author":"Deshimaru","year":"1996","journal-title":"FEBS Lett."},{"key":"10.1016\/j.toxicon.2005.08.016_bib9","first-page":"205","article-title":"Fibrinogen and fibrin","volume":"vol. 45B","author":"Doolittle","year":"1976"},{"key":"10.1016\/j.toxicon.2005.08.016_bib10","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0003-9861(61)90145-X","article-title":"The preparation and properties of two new chromogenic substrates of trypsin","volume":"95","author":"Erlanger","year":"1961","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.toxicon.2005.08.016_bib11","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1042\/bj1180603","article-title":"Proteolytic action of arvin on human fibrinogen","volume":"118","author":"Ewart","year":"1970","journal-title":"Biochem. J."},{"key":"10.1016\/j.toxicon.2005.08.016_bib12","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/0005-2744(72)90187-8","article-title":"Observations concerning the substrate specificity of arvin","volume":"258","author":"Exner","year":"1972","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.toxicon.2005.08.016_bib13","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1042\/bj1310799","article-title":"Studies on the coagulant enzyme from Agkistrodon rhodostoma venom","volume":"131","author":"Hatton","year":"1973","journal-title":"Biochem. J."},{"key":"10.1016\/j.toxicon.2005.08.016_bib14","first-page":"492","article-title":"Use of N-glycanase to release asparagine-linked oligosaccharides for structural analysis","volume":"485","author":"Hirani","year":"1987","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.toxicon.2005.08.016_bib15","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.1016\/S0021-9258(18)61479-6","article-title":"Molecular cloning and sequence analysis of cDNA for batroxobin, a thrombin like snake venom enzyme","volume":"262","author":"Itoh","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.toxicon.2005.08.016_bib16","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1073\/pnas.63.4.1181","article-title":"The rate of molecular evolution considered from the standpoint of population genetics","volume":"63","author":"Kimura","year":"1969","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.toxicon.2005.08.016_bib17","series-title":"MEGA: molecular evolutionary genetics analysis","author":"Kumar","year":"1993"},{"key":"10.1016\/j.toxicon.2005.08.016_bib18","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1093\/bioinformatics\/17.12.1244","article-title":"MEGA2: molecular evolutionary genetics analysis software","volume":"17","author":"Kumar","year":"2001","journal-title":"Bioinformatics"},{"key":"10.1016\/j.toxicon.2005.08.016_bib19","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.toxicon.2005.08.016_bib20","series-title":"Principles of Biochemistry","author":"Lehninger","year":"1982"},{"key":"10.1016\/j.toxicon.2005.08.016_bib21","first-page":"156","article-title":"Thrombin","volume":"vol. 45B","author":"Lundblad","year":"1976"},{"key":"10.1016\/j.toxicon.2005.08.016_bib23","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/0014-5793(93)80205-9","article-title":"The complete amino acid sequence of a thrombin-like enzyme\/gyroxin analogue from venom of the bushmaster snake (Lachasis muta muta)","volume":"329","author":"Magalhaes","year":"1993","journal-title":"FEBS Lett."},{"key":"10.1016\/j.toxicon.2005.08.016_bib22","series-title":"Proteases and Biological Control","first-page":"123","article-title":"Complete primary structure of prothrombin: isolation, structure and reactivity of ten carboxylated glutamic acid residues and regulation of prothrombin activation by thrombin","author":"Magnusson","year":"1975"},{"key":"10.1016\/j.toxicon.2005.08.016_bib24","series-title":"A Laboratory Manual","article-title":"Molecular Cloning","author":"Maniatis","year":"1989"},{"key":"10.1016\/j.toxicon.2005.08.016_bib25","doi-asserted-by":"crossref","first-page":"7328","DOI":"10.1073\/pnas.77.12.7328","article-title":"Nucleotide sequence divergence and functional constraint in mRNA evolution","volume":"77","author":"Miyata","year":"1980","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.toxicon.2005.08.016_bib26","first-page":"1060","article-title":"Graphic presentation of amino acid composition with a modified radar chart","volume":"60","author":"Nakamura","year":"1988","journal-title":"J. Jpn. Biochem. Soc. (Seikagaku)"},{"key":"10.1016\/j.toxicon.2005.08.016_bib27","doi-asserted-by":"crossref","first-page":"5964","DOI":"10.1073\/pnas.90.13.5964","article-title":"Accelerated evolution of Trimeresurus flavoviridis venom gland phospholipase A2 isozymes","volume":"90","author":"Nakashima","year":"1993","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.toxicon.2005.08.016_bib28","doi-asserted-by":"crossref","first-page":"5605","DOI":"10.1073\/pnas.92.12.5605","article-title":"Accelerated evolution in the protein-coding regions is universal in Crotalinae snake venom gland phospholipase A2 isozyme genes","volume":"92","author":"Nakashima","year":"1995","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.toxicon.2005.08.016_bib29","first-page":"418","article-title":"Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions","volume":"3","author":"Nei","year":"1986","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.toxicon.2005.08.016_bib30","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1006\/abbi.1995.1208","article-title":"Primary structure of a coagulant enzyme, bilionebin, from Agkistrodon bilineatus venom","volume":"318","author":"Nikai","year":"1995","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.toxicon.2005.08.016_bib31","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1021\/bi00173a030","article-title":"Purification and characterization of bothrombin, fibrinogen-clotting serine protease from the venom of Bothrops jararaca","volume":"33","author":"Nishida","year":"1994","journal-title":"Biochemistry"},{"key":"10.1016\/j.toxicon.2005.08.016_bib32","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1093\/oxfordjournals.jbchem.a133877","article-title":"Correlation of the amino acid composition of a protein to its structural and biological characters","volume":"91","author":"Nishikawa","year":"1982","journal-title":"J. Biochem. (Tokyo)"},{"key":"10.1016\/j.toxicon.2005.08.016_bib33","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0378-1119(96)00186-2","article-title":"Accelerated evolution of Trimeresurus okinavensis venom gland phospholipase A2-encoding genes","volume":"172","author":"Nobuhisa","year":"1996","journal-title":"Gene"},{"key":"10.1016\/j.toxicon.2005.08.016_bib34","first-page":"205","article-title":"Ancrod, the coagulating enzyme from Malayan Pit viper (Agkistrodon rhodostoma) venom","volume":"vol. 45B","author":"Nolan","year":"1976"},{"key":"10.1016\/j.toxicon.2005.08.016_bib35","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/0041-0101(94)90309-3","article-title":"Purification and characterization of a coagulant enzyme, okinaxobin II, from Trimeresurus okinavensis (himehabu snake) venom which releases fibrinopeptides A and B","volume":"34","author":"Nose","year":"1994","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2005.08.016_bib36","first-page":"435","article-title":"The effect of Formosan snake venom on blood coagulation in vitro","volume":"56","author":"Ouyang","year":"1957","journal-title":"Formosan Med. Assoc."},{"key":"10.1016\/j.toxicon.2005.08.016_bib37","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1055\/s-0038-1653671","article-title":"Purification and properties of the thrombin like principle of Agkistridon acutus venom and its comparison with bovine thrombin","volume":"26","author":"Ouyang","year":"1971","journal-title":"Thromb. Diath. Haemorrh."},{"key":"10.1016\/j.toxicon.2005.08.016_bib38","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0041-0101(79)90221-6","article-title":"The clotting activity of the thrombin-like enzyme of Agkistrodon acutus (Hundred pace snake) venom","volume":"17","author":"Ouyang","year":"1979","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2005.08.016_bib39","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/S0041-0101(02)00092-2","article-title":"Amino acid sequence of a thrombin like enzyme, elegaxobin, from the venom of Trimeresurus elegans (Sakishima-habu)","volume":"40","author":"Oyama","year":"2002","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2005.08.016_bib40","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1006\/bbrc.1999.0203","article-title":"cDNA cloning and expression of acutin","volume":"255","author":"Pan","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.toxicon.2005.08.016_bib41","first-page":"444","article-title":"Thrombin-like enzymes from snake venom: an inventory","volume":"65","author":"Pirkle","year":"1991","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.toxicon.2005.08.016_bib42","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1093\/bioinformatics\/15.2.174","article-title":"DnaSP version 3: an integrated program for molecular population genetics and molecular evolution analysis","volume":"15","author":"Rozas","year":"1999","journal-title":"Bioinformatics"},{"key":"10.1016\/j.toxicon.2005.08.016_bib43","first-page":"406","article-title":"The neighbor-joining method: a new method for the reconstructing phylogenetic tree","volume":"4","author":"Saitou","year":"1987","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.toxicon.2005.08.016_bib44","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1093\/oxfordjournals.jbchem.a135329","article-title":"Purification and characterization of a coagulant enzyme from Trimeresurus flavoviridis venom","volume":"98","author":"Shieh","year":"1985","journal-title":"J. Biochem. (Tokyo)"},{"key":"10.1016\/j.toxicon.2005.08.016_bib45","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1093\/oxfordjournals.jbchem.a122313","article-title":"Amino acid sequence of a coagulant enzyme, flavoxobin, from Trimeresurus flavoviridis venom","volume":"103","author":"Shieh","year":"1988","journal-title":"J. Biochem. (Tokyo)"},{"key":"10.1016\/j.toxicon.2005.08.016_bib46","first-page":"1221","article-title":"Purification and characterization of \u03b1-specific thrombin-like enzymes from the venoms of middle asian pit viper snakes Agkistrodon halis halis and Agkistrodon halis blomhoffii","volume":"58","author":"Solovyov","year":"1993","journal-title":"Biochemistry (Moscow)"},{"key":"10.1016\/j.toxicon.2005.08.016_bib47","doi-asserted-by":"crossref","unstructured":"Spiro, R.G., 1973. Glycoproteins. In: Aufinsen, G.B., Edsal, J.T., Richards, F.M. (Eds.), Advances in Protein Chemistry, vol. 27, Academic Press, New York, pp. 349\u2013407","DOI":"10.1016\/S0065-3233(08)60451-9"},{"key":"10.1016\/j.toxicon.2005.08.016_bib48","series-title":"A Practical Guide to Protein and Peptide Purification for Microsequencing","first-page":"33","article-title":"Enzymatic digestion of proteins and HPLC peptide isolation","author":"Stone","year":"1989"},{"key":"10.1016\/j.toxicon.2005.08.016_bib49","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1042\/0264-6021:3540161","article-title":"Serine protease isoforms of Deinagkistrodon acutus venom; cloning, sequencing and phylogenetic analysis","volume":"354","author":"Wang","year":"2001","journal-title":"Biochem. J."},{"key":"10.1016\/j.toxicon.2005.08.016_bib50","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.0901-9928.2001.890408.x","article-title":"Trimeresurus flavoviridis (habu snake) venom induces human erythrocytes lysis through lipolysis, complement activation and decreased membrane expression of CD55 and CD59","volume":"89","author":"Yamamoto","year":"2001","journal-title":"Pharmacol. Toxicol."},{"key":"10.1016\/j.toxicon.2005.08.016_bib51","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1046\/j.1365-2567.2002.01490.x","article-title":"Flavoxobin, a serine protease from Trimeresurus flavoviridis (habu snake) venom, independently cleaves Arg726-Ser727 of human C3 and acts as a novel, heterologous C3 convertase","volume":"107","author":"Yamamoto","year":"2002","journal-title":"Immunology"}],"container-title":["Toxicon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010105003168?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010105003168?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,20]],"date-time":"2021-07-20T19:57:09Z","timestamp":1626811029000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041010105003168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":51,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["S0041010105003168"],"URL":"https:\/\/doi.org\/10.1016\/j.toxicon.2005.08.016","relation":{},"ISSN":["0041-0101"],"issn-type":[{"value":"0041-0101","type":"print"}],"subject":[],"published":{"date-parts":[[2005,12]]}}}