{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:01:56Z","timestamp":1761742916317},"reference-count":25,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicon"],"published-print":{"date-parts":[[2007,6]]},"DOI":"10.1016\/j.toxicon.2007.02.013","type":"journal-article","created":{"date-parts":[[2007,2,28]],"date-time":"2007-02-28T12:30:58Z","timestamp":1172665858000},"page":"1200-1207","source":"Crossref","is-referenced-by-count":18,"title":["Molecular cloning of serine proteases from elapid snake venoms"],"prefix":"10.1016","volume":"49","author":[{"given":"Yang","family":"Jin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Hui","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.toxicon.2007.02.013_bib1","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.jmb.2004.05.028","article-title":"Improved prediction of signal peptides: SignalP 3.0","volume":"340","author":"Bendtsen","year":"2004","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.toxicon.2007.02.013_bib2","doi-asserted-by":"crossref","first-page":"10609","DOI":"10.1021\/bi034790b","article-title":"Molecular cloning and expression of a functional snake venom serine proteinase, with platelet aggregating activity, from the Cerastes cerastes viper","volume":"42","author":"Dekhil","year":"2003","journal-title":"Biochemistry"},{"key":"10.1016\/j.toxicon.2007.02.013_bib3","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0014-5793(96)01144-1","article-title":"Accelerated evolution of crotalinae snake venom gland serine proteases","volume":"397","author":"Deshimaru","year":"1996","journal-title":"FEBS Lett."},{"key":"10.1016\/j.toxicon.2007.02.013_bib4","doi-asserted-by":"crossref","first-page":"35124","DOI":"10.1074\/jbc.M204372200","article-title":"Ophioluxin, a convulxin-like C-type lectin from Ophiophagus hannah (King cobra) is a powerful platelet activator via glycoprotein VI","volume":"277","author":"Du","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.toxicon.2007.02.013_bib5","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/nature04328","article-title":"Early evolution of the venom system in lizards and snakes","volume":"439","author":"Fry","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.toxicon.2007.02.013_bib6","doi-asserted-by":"crossref","first-page":"4673","DOI":"10.1093\/nar\/22.22.4673","article-title":"CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice","volume":"22","author":"Higgins","year":"1994","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.toxicon.2007.02.013_bib7","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1006\/bbrc.2001.4452","article-title":"Fibrinogenolytic proteases isolated from the snake venom of Taiwan habu: serine proteases with kallikrein-like and angiotensin-degrading activities","volume":"281","author":"Hung","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.toxicon.2007.02.013_bib8","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.1016\/S0021-9258(18)61479-6","article-title":"Molecular cloning and sequence analysis of cDNA for batroxobin, a thrombin-like snake venom enzyme","volume":"262","author":"Itoh","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.toxicon.2007.02.013_bib9","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1093\/bib\/5.2.150","article-title":"MEGA3: integrated software for molecular evolutionary genetics analysis and sequence alignment","volume":"5","author":"Kumar","year":"2004","journal-title":"Brief. Bioinform."},{"key":"10.1016\/j.toxicon.2007.02.013_bib10","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.toxicon.2007.02.013_bib11","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.toxicon.2005.06.011","article-title":"Characterization of a novel protein from Proatheris superciliaris venom: proatherocytin, a 34-kDa platelet receptor PAR1 agonist","volume":"46","author":"Laing","year":"2005","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2007.02.013_bib12","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/0041-0101(95)00077-Y","article-title":"Isolation and properties of a blood coagulation factor X activator from the venom of king cobra (Ophiophagus hannah)","volume":"33","author":"Lee","year":"1995","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2007.02.013_bib13","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1016\/0041-0101(94)90407-3","article-title":"Purification and characterization of l-amino acid oxidase from king cobra (Ophiophagus hannah) venom and its effects on human platelet aggregation","volume":"32","author":"Li","year":"1994","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2007.02.013_bib14","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1016\/S0041-0101(98)00126-3","article-title":"Snake venoms and the hemostatic system","volume":"36","author":"Markland","year":"1998","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2007.02.013_bib15","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1046\/j.1432-1327.1998.2520569.x","article-title":"Purification and amino acid sequence of halystase from snake venom of Agkistrodon halys blomhoffii, a serine protease that cleaves specifically fibrinogen and kininogen","volume":"252","author":"Matsui","year":"1998","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.toxicon.2007.02.013_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbapap.2003.08.001","article-title":"The unusual high molecular mass of Bothrops protease A, a trypsin-like serine peptidase from the venom of Bothrops jararaca, is due to its high carbohydrate content","volume":"1652","author":"Murayama","year":"2003","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.toxicon.2007.02.013_bib17","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/S0969-2126(98)00119-1","article-title":"The crystal structure of the novel snake venom plasminogen activator TSV-PA: a prototype structure for snake venom serine proteinases","volume":"6","author":"Parry","year":"1998","journal-title":"Structure"},{"key":"10.1016\/j.toxicon.2007.02.013_bib18","doi-asserted-by":"crossref","first-page":"29987","DOI":"10.1074\/jbc.272.48.29987","article-title":"Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold","volume":"272","author":"Perona","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.toxicon.2007.02.013_bib19","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/j.toxicon.2005.02.020","article-title":"Snake venom serine proteinases: sequence homology vs. substrate specificity, a paradox to be solved","volume":"45","author":"Serrano","year":"2005","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2007.02.013_bib20","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0041-0101(90)90076-J","article-title":"Isolation and characterization of a hemorrhagin from the venom of Ophiophagus hannah (king cobra)","volume":"28","author":"Tan","year":"1990","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2007.02.013_bib21","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1042\/0264-6021:3540161","article-title":"Serine protease isoforms of Deinagkistrodon acutus venom: cloning, sequencing and phylogenetic analysis","volume":"354","author":"Wang","year":"2001","journal-title":"Biochem. J."},{"key":"10.1016\/j.toxicon.2007.02.013_bib22","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/0041-0101(94)90209-7","article-title":"Characterization of OhS1, an arginine\/lysine amidase from the venom of king cobra (Ophiophagus hannah)","volume":"32","author":"Zhang","year":"1994","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2007.02.013_bib23","doi-asserted-by":"crossref","first-page":"10246","DOI":"10.1074\/jbc.270.17.10246","article-title":"A novel plasminogen activator from snake venom. Purification, characterization, and molecular cloning","volume":"270","author":"Zhang","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.toxicon.2007.02.013_bib24","doi-asserted-by":"crossref","first-page":"20531","DOI":"10.1074\/jbc.272.33.20531","article-title":"Trimeresurus stejnegeri snake venom plasminogen activator. Site-directed mutagenesis and molecular modeling","volume":"272","author":"Zhang","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.toxicon.2007.02.013_bib25","doi-asserted-by":"crossref","first-page":"10524","DOI":"10.1074\/jbc.M412900200","article-title":"Crystal structures and amidolytic activities of two glycosylated snake venom serine proteinases","volume":"280","author":"Zhu","year":"2005","journal-title":"J. Biol. Chem."}],"container-title":["Toxicon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010107000700?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010107000700?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T06:14:54Z","timestamp":1628489694000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041010107000700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":25,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["S0041010107000700"],"URL":"https:\/\/doi.org\/10.1016\/j.toxicon.2007.02.013","relation":{},"ISSN":["0041-0101"],"issn-type":[{"value":"0041-0101","type":"print"}],"subject":[],"published":{"date-parts":[[2007,6]]}}}