{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:05:46Z","timestamp":1769904346001,"version":"3.49.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicon"],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1016\/j.toxicon.2007.04.026","type":"journal-article","created":{"date-parts":[[2007,5,19]],"date-time":"2007-05-19T20:23:17Z","timestamp":1179606197000},"page":"553-562","source":"Crossref","is-referenced-by-count":32,"title":["Crotamine inhibits preferentially fast-twitching muscles but is inactive on sodium channels"],"prefix":"10.1016","volume":"50","author":[{"given":"Carina T.","family":"Rizzi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Lu\u00eds","family":"Carvalho-de-Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Schiavon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Carlos","family":"Cassola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enzo","family":"Wanke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanfranco R.P.","family":"Troncone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.toxicon.2007.04.026_bib1","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0003-9861(92)90418-V","article-title":"Structure\u2013function relationship of myotoxin a using peptide fragments","volume":"298","author":"Baker","year":"1992","journal-title":"Arch. Biochem. Biophys."},{"issue":"1","key":"10.1016\/j.toxicon.2007.04.026_bib2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0006-3495(85)83873-X","article-title":"Saxs study of structure and conformational changes of crotamine","volume":"47","author":"Beltran","year":"1985","journal-title":"Biophys. J."},{"issue":"6","key":"10.1016\/j.toxicon.2007.04.026_bib3","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/BF00258381","article-title":"SAXS study of the snake toxin alpha-crotamine","volume":"17","author":"Beltran","year":"1990","journal-title":"Eur. Biophys. J."},{"issue":"11","key":"10.1016\/j.toxicon.2007.04.026_bib4","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1111\/j.0953-816X.2004.03418.x","article-title":"Postnatal emergence of mature release properties in terminals of rat fast- and slow-twitch muscles","volume":"19","author":"Bewick","year":"2004","journal-title":"Eur. J. Neurosci."},{"issue":"12","key":"10.1016\/j.toxicon.2007.04.026_bib5","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1590\/S0100-879X2001001200004","article-title":"Effects of (60)Co gamma radiation on crotamine","volume":"34","author":"Boni-Mitake","year":"2001","journal-title":"Braz. J. Med. Biol. Res."},{"issue":"1","key":"10.1016\/j.toxicon.2007.04.026_bib6","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0005-2795(78)90457-9","article-title":"Chemical and functional homology of myotoxin a from prairie rattlesnake venom and crotamine from South American rattlesnake venom","volume":"532","author":"Cameron","year":"1978","journal-title":"Biochim. Biophys. Acta"},{"issue":"3","key":"10.1016\/j.toxicon.2007.04.026_bib7","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1111\/j.1476-5381.1978.tb07811.x","article-title":"Effect of crotamine, a toxin of South American rattlesnake venom, on the sodium channel of murine skeletal muscle","volume":"63","author":"Chang","year":"1978","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.toxicon.2007.04.026_bib8","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/j.1476-5381.1983.tb10004.x","article-title":"A study on the membrane depolarization of skeletal muscles caused by a scorpion toxin, sea anemone toxin II and crotamine and the interaction between toxins","volume":"79","author":"Chang","year":"1983","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.toxicon.2007.04.026_bib9","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0041-0101(71)90081-X","article-title":"A comparison of the neuromuscular action of crotamine and the venom of Crotalus durissus terrificus var. crotaminicus. 1. Neuromuscular preparations in situ","volume":"9","author":"Cheymol","year":"1971","journal-title":"Toxicon"},{"issue":"6","key":"10.1016\/j.toxicon.2007.04.026_bib10","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/BF01024904","article-title":"A proton nuclear magnetic resonance study on the solution structure of crotamine","volume":"8","author":"Endo","year":"1989","journal-title":"J. Protein Chem."},{"issue":"Pt 1","key":"10.1016\/j.toxicon.2007.04.026_bib11","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1113\/jphysiol.1996.sp021661","article-title":"A HERG-like K+ channel in rat F-11 DRG cell line: pharmacological identification and biophysical characterization","volume":"496","author":"Faravelli","year":"1996","journal-title":"J. Physiol."},{"issue":"11\u201312","key":"10.1016\/j.toxicon.2007.04.026_bib12","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0041-0101(96)00105-5","article-title":"Similarities and differences in mechanisms of cardiotoxins, melittin and other myotoxins","volume":"34","author":"Fletcher","year":"1996","journal-title":"Toxicon"},{"issue":"2","key":"10.1016\/j.toxicon.2007.04.026_bib13","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF00656997","article-title":"Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches","volume":"391","author":"Hamill","year":"1981","journal-title":"Pflug. Arch."},{"issue":"5","key":"10.1016\/j.toxicon.2007.04.026_bib14","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/0041-0101(78)90142-3","article-title":"Crotamine conformation: effect of pH and temperature","volume":"16","author":"Hampe","year":"1978","journal-title":"Toxicon"},{"issue":"1","key":"10.1016\/j.toxicon.2007.04.026_bib15","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/S0167-4889(99)00082-8","article-title":"Identification of 30kDa protein for Ca(2+) releasing action of myotoxin a with a mechanism common to DIDS in skeletal muscle sarcoplasmic reticulum","volume":"1451","author":"Hirata","year":"1999","journal-title":"Biochim. Biophys. Acta"},{"issue":"4","key":"10.1016\/j.toxicon.2007.04.026_bib16","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/0041-0101(83)90128-9","article-title":"Potentiation by crotamine of the depolarizing effects of batrachotoxin, protoveratrine A and grayanotoxin I on the rat diaphragm","volume":"21","author":"Hong","year":"1983","journal-title":"Toxicon"},{"issue":"12","key":"10.1016\/j.toxicon.2007.04.026_bib17","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1096\/fj.03-1459fje","article-title":"Crotamine is a novel cell-penetrating protein from the venom of rattlesnake Crotalus durissus terrificus","volume":"18","author":"Kerkis","year":"2004","journal-title":"FASEB J."},{"issue":"2","key":"10.1016\/j.toxicon.2007.04.026_bib18","first-page":"213","article-title":"The primary structure of crotamine (author's translation)","volume":"356","author":"Laure","year":"1975","journal-title":"Hoppe Seylers Z. Physiol. Chem."},{"issue":"2","key":"10.1016\/j.toxicon.2007.04.026_bib19","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.toxicon.2004.03.028","article-title":"Using the deadly mu-conotoxins as probes of voltage-gated sodium channels","volume":"44","author":"Li","year":"2004","journal-title":"Toxicon"},{"issue":"2\u20133","key":"10.1016\/j.toxicon.2007.04.026_bib21","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0014-2999(98)00152-6","article-title":"Tension generation and increase in voltage-activated Na+current by crotamine","volume":"348","author":"Matavel","year":"1998","journal-title":"Eur. J. Pharmacol."},{"issue":"1\u20133","key":"10.1016\/j.toxicon.2007.04.026_bib20","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0014-5793(02)02988-5","article-title":"Electrophysiological characterization and molecular identification of the Phoneutria nigriventer peptide toxin PnTx2-6","volume":"523","author":"Matavel","year":"2002","journal-title":"FEBS Lett."},{"issue":"1","key":"10.1016\/j.toxicon.2007.04.026_bib22","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0003-9861(88)90247-0","article-title":"Characterization of nicked myotoxin a and its effect on the sarcoplasmic reticulum calcium pump","volume":"266","author":"Mori","year":"1988","journal-title":"Arch. Biochem. Biophys."},{"issue":"9","key":"10.1016\/j.toxicon.2007.04.026_bib23","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1046\/j.1432-1033.2003.03563.x","article-title":"Solution structure of crotamine, a Na+channel affecting toxin from Crotalus durissus terrificus venom","volume":"270","author":"Nicastro","year":"2003","journal-title":"Eur. J. Biochem."},{"issue":"32","key":"10.1016\/j.toxicon.2007.04.026_bib24","doi-asserted-by":"crossref","first-page":"33323","DOI":"10.1074\/jbc.M404344200","article-title":"Binding specificity of sea anemone toxins to Nav 1.1\u20131.6 sodium channels: unexpected contributions from differences in the IV\/S3\u2013S4 outer loop","volume":"279","author":"Oliveira","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.toxicon.2007.04.026_bib25","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1093\/oxfordjournals.jbchem.a123132","article-title":"Interchain disulfide bonds in crotamine self-association","volume":"107","author":"Teno","year":"1990","journal-title":"J. Biochem. (Tokyo)"},{"issue":"1 (Suppl. 1)","key":"10.1016\/j.toxicon.2007.04.026_bib26","first-page":"R38","article-title":"Regional brain c-Fos activation associated with penile erection and other symptoms by the spider toxin TX2-6","volume":"358","author":"Troncone","year":"1998","journal-title":"Naunyn-Schmiedebergs Arch. Pharmacol."},{"issue":"Pt 6","key":"10.1016\/j.toxicon.2007.04.026_bib27","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1046\/j.1469-7580.2001.19960631.x","article-title":"Fibre type regionalisation in lower hindlimb muscles of rabbit, rat and mouse: a comparative study","volume":"199","author":"Wang","year":"2001","journal-title":"J. Anat."},{"issue":"Pt. 3","key":"10.1016\/j.toxicon.2007.04.026_bib28","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1046\/j.1469-7580.2001.19830295.x","article-title":"Quantification of fibre type regionalisation: an analysis of lower hindlimb muscles in the rat","volume":"198","author":"Wang","year":"2001","journal-title":"J. Anat."},{"issue":"2","key":"10.1016\/j.toxicon.2007.04.026_bib29","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.toxicon.2004.05.016","article-title":"Blockade of neuronal nitric oxide synthase abolishes the toxic effects of Tx2-5, a lethal Phoneutria nigriventer spider toxin","volume":"44","author":"Yonamine","year":"2004","journal-title":"Toxicon"}],"container-title":["Toxicon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010107001699?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010107001699?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,28]],"date-time":"2019-04-28T05:39:05Z","timestamp":1556429945000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041010107001699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["S0041010107001699"],"URL":"https:\/\/doi.org\/10.1016\/j.toxicon.2007.04.026","relation":{},"ISSN":["0041-0101"],"issn-type":[{"value":"0041-0101","type":"print"}],"subject":[],"published":{"date-parts":[[2007,9]]}}}