{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T21:14:03Z","timestamp":1790198043239,"version":"4.1.0"},"reference-count":84,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicon"],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1016\/j.toxicon.2007.06.022","type":"journal-article","created":{"date-parts":[[2007,7,5]],"date-time":"2007-07-05T11:16:35Z","timestamp":1183634195000},"page":"757-778","source":"Crossref","is-referenced-by-count":128,"title":["Spatial and temporal patterns of alkaloid variation in the poison frog Oophaga pumilio in Costa Rica and Panama over 30 years"],"prefix":"10.1016","volume":"50","author":[{"given":"Ralph A.","family":"Saporito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen A.","family":"Donnelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poonam","family":"Jain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Martin Garraffo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas F.","family":"Spande","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John W.","family":"Daly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.toxicon.2007.06.022_bib1","series-title":"Host-Plant Selection by Phytophagous Insects","author":"Bernays","year":"1994"},{"issue":"1","key":"10.1016\/j.toxicon.2007.06.022_bib2","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/BF01021277","article-title":"Lepidoptera and pyrrolizidine alkaloids: exemplification of complexity in chemical ecology","volume":"16","author":"Boppre","year":"1990","journal-title":"J. Chem. Ecol."},{"issue":"3","key":"10.1016\/j.toxicon.2007.06.022_bib3","doi-asserted-by":"crossref","first-page":"586","DOI":"10.2307\/2408226","article-title":"Unpalatability as a defense strategy of Euphydryas phaeton (Lepidoptera: Nymphalidae)","volume":"34","author":"Bowers","year":"1980","journal-title":"Evolution"},{"key":"10.1016\/j.toxicon.2007.06.022_bib4","series-title":"Insect Defenses: Adaptive Mechanisms and Strategies of Prey and Predators","first-page":"353","article-title":"Recycling plant natural products for insect defense","author":"Bowers","year":"1990"},{"issue":"3","key":"10.1016\/j.toxicon.2007.06.022_bib5","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/j.1365-2311.1995.tb00449.x","article-title":"Variable chemical defense in the checkerspot butterfly Euphydryas gillettii (Lepidoptera: Nymphalidae)","volume":"20","author":"Bowers","year":"1995","journal-title":"Ecol. Entomol."},{"issue":"2","key":"10.1016\/j.toxicon.2007.06.022_bib6","doi-asserted-by":"crossref","first-page":"264","DOI":"10.2307\/1563424","article-title":"The antipredator functions of Dendrobates auratus (Amphibia, Anura, Dendrobatidae) skin secretion in regard to a snake predator (Thamnophis)","volume":"12","author":"Brodie","year":"1978","journal-title":"J. Herpetol."},{"issue":"4","key":"10.1016\/j.toxicon.2007.06.022_bib7","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1073\/pnas.57.4.893","article-title":"Plant poisons in a terrestrial food chain","volume":"57","author":"Brower","year":"1967","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.toxicon.2007.06.022_bib8","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1126\/science.161.3848.1349","article-title":"Ecological chemistry and the palatability spectrum","volume":"161","author":"Brower","year":"1968","journal-title":"Science"},{"issue":"33","key":"10.1016\/j.toxicon.2007.06.022_bib9","doi-asserted-by":"crossref","first-page":"11617","DOI":"10.1073\/pnas.0503502102","article-title":"Convergent evolution of chemical defense in poison frogs and arthropod prey between Madagascar and the neotropics","volume":"102","author":"Clark","year":"2005","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"10","key":"10.1016\/j.toxicon.2007.06.022_bib10","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1007\/s10886-006-9144-6","article-title":"Individual variation in alkaloid content of poison frogs of Madagascar (Mantella; Mantellidae)","volume":"32","author":"Clark","year":"2006","journal-title":"J. Chem. Ecol."},{"issue":"3\u20134","key":"10.1016\/j.toxicon.2007.06.022_bib11","first-page":"173","article-title":"Lady bug defense alkaloids: structural, chemotaxonomic, and biosynthetic aspects","volume":"5","author":"Daloze","year":"1995","journal-title":"Chemoecology"},{"key":"10.1016\/j.toxicon.2007.06.022_bib12","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1021\/jm0204845","article-title":"Amphibian skin; a remarkable source of biologically active arthropod alkaloids","volume":"46","author":"Daly","year":"2003","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.toxicon.2007.06.022_bib13","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1126\/science.156.3777.970","article-title":"Toxicity of Panamanian poison frogs (Dendrobates): some biological and chemical aspects","volume":"156","author":"Daly","year":"1967","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.toxicon.2007.06.022_bib14","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0041-0101(78)90036-3","article-title":"Classification of skin alkaloids from neotropical poison-dart frogs (Dendrobatidae)","volume":"16","author":"Daly","year":"1978","journal-title":"Toxicon"},{"issue":"2","key":"10.1016\/j.toxicon.2007.06.022_bib15","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1021\/np50044a012","article-title":"Alkaloids from dendrobatid frogs: structures of two \u03c9-hydroxy congeners of 3-butyl-5-propylindolizidines and occurrence of 2,5-disubstituted pyrrolidines and a 2,6-disubstituted piperidine","volume":"49","author":"Daly","year":"1986","journal-title":"J. Nat. Prod."},{"issue":"10","key":"10.1016\/j.toxicon.2007.06.022_bib16","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/0041-0101(87)90265-0","article-title":"Further classification of skin alkaloids from neotropical poison frogs (Dendrobatidae), with a general survey of toxic\/noxious substances in the amphibia","volume":"25","author":"Daly","year":"1987","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2007.06.022_bib17","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1021\/np50068a020","article-title":"Alkaloids from Australian frogs: pseudophrynamines and pumiliotoxins","volume":"53","author":"Daly","year":"1990","journal-title":"J. Nat. Prod."},{"issue":"8","key":"10.1016\/j.toxicon.2007.06.022_bib18","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/0041-0101(92)90387-K","article-title":"Variability in alkaloid profiles in neotropical poison frogs (Dendrobatidae): genetic versus environmental determinants","volume":"30","author":"Daly","year":"1992","journal-title":"Toxicon"},{"issue":"4","key":"10.1016\/j.toxicon.2007.06.022_bib19","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1007\/BF02059589","article-title":"Dietary source for skin alkaloids of poison frogs (Dendrobatidae)?","volume":"20","author":"Daly","year":"1994","journal-title":"J. Chem. Ecol."},{"issue":"6","key":"10.1016\/j.toxicon.2007.06.022_bib20","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/0041-0101(94)90335-2","article-title":"An uptake system for dietary alkaloids in poison frogs (Dendrobatidae)","volume":"32","author":"Daly","year":"1994","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2007.06.022_bib21","first-page":"1","article-title":"Madagascan poison frogs (Mantella) and their skin alkaloids","volume":"3177","author":"Daly","year":"1996","journal-title":"Am. Mus. Novit."},{"issue":"7","key":"10.1016\/j.toxicon.2007.06.022_bib22","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/S0041-0101(96)00212-7","article-title":"Absence of skin alkaloids in captive-raised Madagascan mantelline frogs (Mantella) and sequestration of dietary alkaloids","volume":"35","author":"Daly","year":"1997","journal-title":"Toxicon"},{"issue":"1","key":"10.1016\/j.toxicon.2007.06.022_bib23","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1023\/A:1005437427326","article-title":"Arthropod-frog connection: decahydroquinoline and pyrrolizidine alkaloids common to microsympatric myrmicine ants and dendrobatid frogs","volume":"26","author":"Daly","year":"2000","journal-title":"J. Chem. Ecol."},{"issue":"22","key":"10.1016\/j.toxicon.2007.06.022_bib24","doi-asserted-by":"crossref","first-page":"13996","DOI":"10.1073\/pnas.222551599","article-title":"Bioactive alkaloids of frog skins: combinatorial bioprospecting reveals that pumiliotoxins have an arthropod source","volume":"99","author":"Daly","year":"2002","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"19","key":"10.1016\/j.toxicon.2007.06.022_bib25","doi-asserted-by":"crossref","first-page":"11092","DOI":"10.1073\/pnas.1834430100","article-title":"Evidence for an enantioselective pumiliotoxin 7-hydroxylase in dendrobatid poison frogs of the genus Dendrobates","volume":"100","author":"Daly","year":"2003","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"10","key":"10.1016\/j.toxicon.2007.06.022_bib26","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1021\/np0580560","article-title":"Alkaloids from amphibian skin: a tabulation of over eight-hundred compounds","volume":"68","author":"Daly","year":"2005","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.toxicon.2007.06.022_bib27","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1007\/s10886-007-9261-x","article-title":"Alkaloids in bufonid toads (Melanophryniscus): temporal and Geographic determinants for two Argentinian species","volume":"33","author":"Daly","year":"2007","journal-title":"J. Chem. Ecol."},{"key":"10.1016\/j.toxicon.2007.06.022_bib28","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1038\/nature04297","article-title":"Predator learning favors mimicry of a less-toxic model in poison frogs","volume":"440","author":"Darst","year":"2006","journal-title":"Nature"},{"issue":"15","key":"10.1016\/j.toxicon.2007.06.022_bib29","doi-asserted-by":"crossref","first-page":"5852","DOI":"10.1073\/pnas.0600625103","article-title":"A mechanism for diversity in warning signals: conspicuousness versus toxicity in poison frogs","volume":"103","author":"Darst","year":"2006","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"2","key":"10.1016\/j.toxicon.2007.06.022_bib30","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0041-0101(99)00147-6","article-title":"Venom alkaloids of fire ants in relation to worker size and age","volume":"38","author":"Deslippe","year":"2000","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2007.06.022_bib31","doi-asserted-by":"crossref","first-page":"723","DOI":"10.2307\/1446399","article-title":"Feeding patterns of the strawberry poison frog, Dendrobates pumilio (Anura: Dendrobatidae)","volume":"3","author":"Donnelly","year":"1991","journal-title":"Copeia"},{"issue":"45","key":"10.1016\/j.toxicon.2007.06.022_bib32","doi-asserted-by":"crossref","first-page":"15857","DOI":"10.1073\/pnas.0407197101","article-title":"Melyrid beetles (Choresine): a putative source for the batrachotoxin alkaloids found in poison-dart frogs and passerine birds","volume":"101","author":"Dumbacher","year":"2004","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"6","key":"10.1016\/j.toxicon.2007.06.022_bib33","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1021\/np50060a023","article-title":"Alkaloids from a Panamanian poison frog, Dendrobates speciosus: identification of pumiliotoxin-A and allopumiliotoxin class alkaloids, 3,5-disubstituted indolizidines, 5-substituted 8-methylindolizidines, and a 2-methyl-6-nonyl-4-hydroxy-piperidine","volume":"51","author":"Edwards","year":"1988","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.toxicon.2007.06.022_bib34","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/291067a0","article-title":"Birds can overcome the cardenolide defence of monarch butterflies in Mexico","volume":"291","author":"Fink","year":"1981","journal-title":"Nature"},{"issue":"12","key":"10.1016\/j.toxicon.2007.06.022_bib35","doi-asserted-by":"crossref","first-page":"2835","DOI":"10.1007\/s10886-005-8397-9","article-title":"Phenological variation in chemical defense of the pipevine swallowtail","volume":"31","author":"Fordyce","year":"2005","journal-title":"J. Chem. Ecol."},{"issue":"2","key":"10.1016\/j.toxicon.2007.06.022_bib36","doi-asserted-by":"crossref","first-page":"158","DOI":"10.2307\/2387719","article-title":"The aposematically colored frog, Dendrobates pumilio, is distasteful to the large, predatory ant, Paraponera clavata","volume":"13","author":"Fritz","year":"1981","journal-title":"Biotropica"},{"key":"10.1016\/j.toxicon.2007.06.022_bib37","series-title":"Herbivores: Their Interactions with Secondary Plant Metabolites","first-page":"439","article-title":"Evolution and coevolution of plants and phytophagous arthropods","author":"Futuyma","year":"1992"},{"issue":"7","key":"10.1016\/j.toxicon.2007.06.022_bib38","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1021\/np50097a005","article-title":"Alkaloids in madagascan frogs (Mantella): pumiliotoxins, indolizidines, quinolizidines, and pyrrolizidines","volume":"56","author":"Garraffo","year":"1993","journal-title":"J. Nat. Prod."},{"issue":"3","key":"10.1016\/j.toxicon.2007.06.022_bib39","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1021\/np50093a008","article-title":"Alkaloids from bufonid toads (Melanophryniscus): decahydroquinolines, pumiliotoxins and homopumiliotoxins, indolizidines, pyrrolizidines, and quinolizidines","volume":"56","author":"Garraffo","year":"1993","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.toxicon.2007.06.022_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1206\/0003-0090(2006)299[1:PSODFA]2.0.CO;2","article-title":"Phylogenetic systematics of dart-poison frogs and their relatives (Amphibia: Athesphatanura: Dendrobatidae)","volume":"299","author":"Grant","year":"2006","journal-title":"Bull. Am. Mus. Nat. Hist."},{"issue":"1","key":"10.1016\/j.toxicon.2007.06.022_bib41","first-page":"73","article-title":"Dendrobates pumilio (Poison frog) poisoning","volume":"37","author":"Hagman","year":"2006","journal-title":"Herpetol. Rev."},{"key":"10.1016\/j.toxicon.2007.06.022_bib42","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/3-540-48146-X_5","article-title":"Biosynthesis and metabolism of pyrrolizidine alkaloids in plants and specialized insect herbivores","volume":"209","author":"Hartmann","year":"2000","journal-title":"Top. Curr. Chem."},{"key":"10.1016\/j.toxicon.2007.06.022_bib43","first-page":"155","article-title":"Chemistry, biology, and chemoecology of the pyrrolizidine alkaloids","volume":"vol. 9","author":"Hartmann","year":"1995"},{"issue":"3","key":"10.1016\/j.toxicon.2007.06.022_bib44","doi-asserted-by":"crossref","first-page":"687","DOI":"10.2307\/1935359","article-title":"Sweep samples of tropical foliage insects: effects of seasons, vegetation types, elevation, time of day and insularity","volume":"54","author":"Janzen","year":"1973","journal-title":"Ecology"},{"issue":"1","key":"10.1016\/j.toxicon.2007.06.022_bib45","doi-asserted-by":"crossref","first-page":"96","DOI":"10.2307\/1933565","article-title":"Differences in insect abundance and diversity between wetter and drier sites during a tropical dry season","volume":"49","author":"Janzen","year":"1968","journal-title":"Ecology"},{"issue":"3","key":"10.1016\/j.toxicon.2007.06.022_bib46","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2307\/2989685","article-title":"Changes in the arthropod community along an elevational transect in the Venezuelan Andes","volume":"8","author":"Janzen","year":"1976","journal-title":"Biotropica"},{"issue":"5","key":"10.1016\/j.toxicon.2007.06.022_bib47","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1023\/A:1020898229304","article-title":"Further alkaloids common to ants and frogs: decahydroquinolines and a quinolizidine","volume":"25","author":"Jones","year":"1999","journal-title":"J. Chem. Ecol."},{"issue":"2","key":"10.1016\/j.toxicon.2007.06.022_bib48","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1021\/np068034t","article-title":"Venom chemistry of the ant Myrmicaria melanogaster from Brunei","volume":"70","author":"Jones","year":"2007","journal-title":"J. Nat. Prod."},{"issue":"4","key":"10.1016\/j.toxicon.2007.06.022_bib49","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0305-1978(99)00073-3","article-title":"New records for pyrrolizidine alkaloid-feeding insects. Hemiptera and Coleoptera on Senecio brasiliensis","volume":"28","author":"Klitzke","year":"2000","journal-title":"Biochem. Syst. Ecol."},{"issue":"4","key":"10.1016\/j.toxicon.2007.06.022_bib50","doi-asserted-by":"crossref","first-page":"435","DOI":"10.2307\/1942647","article-title":"Seasonal, annual, and among site variation in the ground ant community of a deciduous tropical forest: some causes of patchy species distributions","volume":"53","author":"Levings","year":"1983","journal-title":"Ecol. Monogr."},{"key":"10.1016\/j.toxicon.2007.06.022_bib51","series-title":"The Ecology of a Tropical Forest Seasonal Rhythms and Long-term Changes","first-page":"355","article-title":"Seasonal and annual variation in litter arthropod populations","author":"Levings","year":"1982"},{"issue":"2","key":"10.1016\/j.toxicon.2007.06.022_bib52","doi-asserted-by":"crossref","first-page":"125","DOI":"10.2307\/2387844","article-title":"Litter moisture content as a determinant of litter arthropod distribution and abundance during the dry season on Barro Colorado Island, Panama","volume":"16","author":"Levings","year":"1984","journal-title":"Biotropica"},{"key":"10.1016\/j.toxicon.2007.06.022_bib53","first-page":"27","article-title":"Analysis of the leaf litter arthropod fauna of a lowland tropical evergreen forest site (La Selva, Costa Rica)","volume":"30","author":"Lieberman","year":"1982","journal-title":"Rev. Biol. Trop."},{"key":"10.1016\/j.toxicon.2007.06.022_bib54","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1515\/znc-2005-11-1218","article-title":"Alkaloids of anuran skin: antimicrobial function?","volume":"60c","author":"Macfoy","year":"2005","journal-title":"Z. Naturforsch."},{"issue":"6","key":"10.1016\/j.toxicon.2007.06.022_bib55","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.toxicon.2005.07.004","article-title":"Studies on the poisonous skin secretions of individual red bellied toads, Melanophryniscus montevidensis (Anura, Bufonidae), from Uruguay","volume":"46","author":"Mebs","year":"2005","journal-title":"Toxicon"},{"issue":"5","key":"10.1016\/j.toxicon.2007.06.022_bib56","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1023\/A:1022329702632","article-title":"Geographic and temporal variation of cardienolide-based chemical defenses of queen butterfly (Danaus gilippus) in northern Florida","volume":"24","author":"Moranz","year":"1998","journal-title":"J. Chem. Ecol."},{"issue":"3","key":"10.1016\/j.toxicon.2007.06.022_bib57","first-page":"175","article-title":"Preliminary evaluation of skin toxins and vocalizations in taxonomic and evolutionary studies of poison-dart frogs (Dendrobatidae)","volume":"157","author":"Myers","year":"1976","journal-title":"Bull. Am. Mus. Nat. Hist."},{"key":"10.1016\/j.toxicon.2007.06.022_bib58","first-page":"1","article-title":"A name for the poison frog of Cordillera Azul, Eastern Peru, with notes on its biology and skin toxins (Dendrobatidae)","volume":"2674","author":"Myers","year":"1979","journal-title":"Am. Mus. Novit."},{"key":"10.1016\/j.toxicon.2007.06.022_bib59","first-page":"1","article-title":"Taxonomy and ecology of Dendrobates bombetes, a new Andean poison frog with new skin toxins","volume":"2692","author":"Myers","year":"1980","journal-title":"Am. Mus. Novit."},{"issue":"2","key":"10.1016\/j.toxicon.2007.06.022_bib60","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/scientificamerican0283-120","article-title":"Dart-poison frogs","volume":"248","author":"Myers","year":"1983","journal-title":"Sci. Am."},{"key":"10.1016\/j.toxicon.2007.06.022_bib61","first-page":"1","article-title":"An arboreal poison frog (Dendrobates) from western Panama","volume":"2783","author":"Myers","year":"1984","journal-title":"Am. Mus. Novit."},{"key":"10.1016\/j.toxicon.2007.06.022_bib62","first-page":"1","article-title":"Discovery of the Costa Rican poison frog Dendrobates granuliferus in sympatry with Dendrobates pumilio, and comments on taxanomic use of skin alkaloids","volume":"3144","author":"Myers","year":"1995","journal-title":"Am. Mus. Novit."},{"issue":"4","key":"10.1016\/j.toxicon.2007.06.022_bib63","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/0040-8166(79)90029-6","article-title":"Morphology of the granular secretory glands in skin of poison-dart frogs (Dendrobatidae)","volume":"11","author":"Neuwirth","year":"1979","journal-title":"Tissue Cell"},{"key":"10.1016\/j.toxicon.2007.06.022_bib64","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1146\/annurev.ento.47.091201.145121","article-title":"Sequestration of defensive substances from plants by Lepidoptera","volume":"47","author":"Nishida","year":"2002","journal-title":"Annu. Rev. Entomol."},{"issue":"22","key":"10.1016\/j.toxicon.2007.06.022_bib65","doi-asserted-by":"crossref","first-page":"12792","DOI":"10.1073\/pnas.2133521100","article-title":"Multiple, recurring origins of aposematism and diet specialization in poison frogs","volume":"100","author":"Santos","year":"2003","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"12","key":"10.1016\/j.toxicon.2007.06.022_bib66","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.1023\/B:JOEC.0000008065.28364.a0","article-title":"A siphonotid millipede (Rhinotus) as the source of spiropyrrolizidine oximes of dendrobatid frogs","volume":"29","author":"Saporito","year":"2003","journal-title":"J. Chem. Ecol."},{"issue":"21","key":"10.1016\/j.toxicon.2007.06.022_bib67","doi-asserted-by":"crossref","first-page":"8045","DOI":"10.1073\/pnas.0402365101","article-title":"Formicine ants: an arthropod source for the pumiliotoxin alkaloids of dendrobatid poison frogs","volume":"101","author":"Saporito","year":"2004","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"4","key":"10.1016\/j.toxicon.2007.06.022_bib68","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1007\/s10886-006-9034-y","article-title":"Geographic and seasonal variation in alkaloid-based chemical defenses of Dendrobates pumilio from Bocas del Toro, Panama","volume":"32","author":"Saporito","year":"2006","journal-title":"J. Chem. Ecol."},{"key":"10.1016\/j.toxicon.2007.06.022_bib69","doi-asserted-by":"crossref","unstructured":"Saporito, R.A., Zuercher, R., Roberts, M., Gerow, K.G., Donnelly, M.A., 2007a. Experimental evidence for aposematism in the dendrobatid frog Oophaga pumilio. Copeia, in press.","DOI":"10.1643\/0045-8511(2007)7[1006:EEFAIT]2.0.CO;2"},{"issue":"21","key":"10.1016\/j.toxicon.2007.06.022_bib70","doi-asserted-by":"crossref","first-page":"8885","DOI":"10.1073\/pnas.0702851104","article-title":"Oribatid mites: a major dietary source for alkaloids in poison frogs","volume":"104","author":"Saporito","year":"2007","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.toxicon.2007.06.022_bib71","series-title":"The Amphibians and Reptiles of Costa Rica: A Herpetofauna Between Two Continents, between Two Seas","author":"Savage","year":"2002"},{"key":"10.1016\/j.toxicon.2007.06.022_bib72","unstructured":"Silverstone, P.A., 1975. A revision of the poison arrow frogs of the genus Dendrobates Wagler. Natural History Museum of Los Angeles County Science Bulletin no. 25, pp. 1\u201355."},{"key":"10.1016\/j.toxicon.2007.06.022_bib73","unstructured":"Silverstone, P.A., 1976. A revision of the poison arrow frogs of the genus Phyllobates Bibron in Sagra (family Dendrobatidae). Natural History Museum of Los Angeles County Science Bulletin. no. 27, pp. 1\u201353."},{"issue":"4","key":"10.1016\/j.toxicon.2007.06.022_bib74","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1021\/np010506a","article-title":"Evidence of biosynthesis of pseudophrynamine alkaloids by an Australian myobatrachid frog (Pseudophryne) and for sequestration of dietary pumiliotoxins","volume":"65","author":"Smith","year":"2002","journal-title":"J. Nat. Prod."},{"issue":"1","key":"10.1016\/j.toxicon.2007.06.022_bib75","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1021\/np980298v","article-title":"Occurrence and significance of decahydroquinolines from dendrobatid poison frogs and a myrmicine ant: use of 1H and 13C NMR in their conformational analysis","volume":"62","author":"Spande","year":"1999","journal-title":"J. Nat. Prod."},{"issue":"11","key":"10.1016\/j.toxicon.2007.06.022_bib76","doi-asserted-by":"crossref","first-page":"6227","DOI":"10.1073\/pnas.101134898","article-title":"The evolution of coloration and toxicity in the poison frog family (Dendrobatidae)","volume":"98","author":"Summers","year":"2001","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"4","key":"10.1016\/j.toxicon.2007.06.022_bib77","doi-asserted-by":"crossref","first-page":"345","DOI":"10.2307\/2388601","article-title":"Unpalatability of the poison arrow frog Dendrobates pumilio to the ctenid spider Cupiennius coccineus","volume":"17","author":"Szelistowski","year":"1985","journal-title":"Biotropica"},{"issue":"10","key":"10.1016\/j.toxicon.2007.06.022_bib78","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1007\/s10886-005-7109-9","article-title":"Scheloribatid mites as the source of pumiliotoxins in dendrobatid frogs","volume":"31","author":"Takada","year":"2005","journal-title":"J. Chem. Ecol."},{"key":"10.1016\/j.toxicon.2007.06.022_bib79","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1098\/rspb.2001.1859","article-title":"Dual chemical sequestration: a key mechanism in transitions among ecological specialization","volume":"269","author":"Termonia","year":"2001","journal-title":"Proc. R. Soc. Lond."},{"key":"10.1016\/j.toxicon.2007.06.022_bib80","unstructured":"Toft, C.A., Levings, S.C., 1997. Tendencias estacionales relacionadas con las poblaciones de artropodos en la hojorasca. In: Actas del IV Symposium Internacional de Ecologia Tropical, 2, pp. 559\u2013576."},{"issue":"13","key":"10.1016\/j.toxicon.2007.06.022_bib81","doi-asserted-by":"crossref","first-page":"3453","DOI":"10.1016\/S0040-4020(01)87312-9","article-title":"Alkaloids from dendrobatid poison frogs: trans-decahydroquinolines and indolizidines","volume":"42","author":"Tokuyama","year":"1986","journal-title":"Tetrahedron"},{"key":"10.1016\/j.toxicon.2007.06.022_bib82","first-page":"579","article-title":"Caste specific alkaloid chemistry of Solenopsis maboya and S. torresi (Hymenoptera: Formicidae)","volume":"37","author":"Torres","year":"2001","journal-title":"Sociobiology"},{"key":"10.1016\/j.toxicon.2007.06.022_bib83","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1078\/1439-6092-00076","article-title":"Convergent evolution of aposematic coloration in Neotropical poison frogs: a molecular phylogenetic perspective","volume":"3","author":"Vences","year":"2003","journal-title":"Organ. Divers. Evol."},{"issue":"47","key":"10.1016\/j.toxicon.2007.06.022_bib84","doi-asserted-by":"crossref","first-page":"17818","DOI":"10.1073\/pnas.0608646103","article-title":"A common pumiliotoxin from poison frogs exhibits enantioselective toxicity against mosquitoes","volume":"103","author":"Weldon","year":"2006","journal-title":"Proc. Natl. Acad. Sci."}],"container-title":["Toxicon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004101010700219X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004101010700219X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T03:39:18Z","timestamp":1556595558000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S004101010700219X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":84,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["S004101010700219X"],"URL":"https:\/\/doi.org\/10.1016\/j.toxicon.2007.06.022","relation":{},"ISSN":["0041-0101"],"issn-type":[{"value":"0041-0101","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]}}}