{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:10:13Z","timestamp":1784247013580,"version":"3.55.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,7,15]],"date-time":"2014-07-15T00:00:00Z","timestamp":1405382400000},"content-version":"vor","delay-in-days":317,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006507","name":"Funda\u00e7\u00e3o Oswaldo Cruz","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006507","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicon"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.toxicon.2013.06.004","type":"journal-article","created":{"date-parts":[[2013,6,21]],"date-time":"2013-06-21T00:26:25Z","timestamp":1371774385000},"page":"90-101","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["Linear B-cell epitopes in BthTX-1, BthTX-II and BthA-1, phospholipase A2's from Bothrops jararacussu snake venom, recognized by therapeutically neutralizing commercial horse antivenom"],"prefix":"10.1016","volume":"72","author":[{"given":"Salvatore G.","family":"De-Simone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paloma","family":"Napole\u00e3o-Pego","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz A.L.","family":"Teixeira-Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathas D.L.","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thatiane S.","family":"De-Simone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anibal R.","family":"Melgarejo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aniesse S.","family":"Aguiar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela P.","family":"Marchi-Salvador","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.toxicon.2013.06.004_bib1","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/S0041-0101(00)00227-0","article-title":"Immunochemical properties of the N-terminal helix of myotoxin II, a lysine-49 phospholipase A2 from Bothrops asper snake venom","volume":"39","author":"Angulo","year":"2001","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib2","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0041-0101(96)00036-0","article-title":"Phospholipase A2 \u2013 a structural review","volume":"34","author":"Arni","year":"1996","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib3","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/0041-0101(93)90132-3","article-title":"Immunochemical cross-reactivity of neurotoxic phospholipase A2 enzymes from Indian cobra (Naja naja naja) venom using polyclonal antibodies","volume":"31","author":"Basavarajappa","year":"1993","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib4","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.toxicon.2005.06.018","article-title":"Cross-neutralization of the neurotoxicity of Crotalus durissus terrificus and Bothrops jararacussu venoms by antisera against crotoxin and phospholipase A2 from Crotalus durissus cascavella venom","volume":"46","author":"Beghini","year":"2007","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib5","series-title":"A defesa contra o ofidismo","author":"Brazil","year":"1911"},{"key":"10.1016\/j.toxicon.2013.06.004_bib6","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1006\/abbi.1998.0853","article-title":"Immunochemical characterization and role in toxic activities of region 115-129 of myotoxin II, a Lys49 phospholipase A2 from Bothrops asper snake venom","volume":"358","author":"Calder\u00f3n","year":"1998","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.toxicon.2013.06.004_bib7","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0041-0101(97)00051-2","article-title":"The three dimensional structures of two toxins from snake venom throw light on the anticoagulant and neurotoxic sites of phospholipase A2","volume":"36","author":"Carredano","year":"1998","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib8","first-page":"126","article-title":"Neurotoxins with phospholipase A2 activity in snake venoms","volume":"9","author":"Chang","year":"1985","journal-title":"Proc. Natl. Sci. Counc. Repub. China B"},{"key":"10.1016\/j.toxicon.2013.06.004_bib9","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/j.bbamem.2007.01.023","article-title":"Mapping of the structural determinants of artificial and biological membrane damaging activities of a Lys49 phospholipase A(2) by scanning alanine mutagenesis","volume":"1768","author":"Chioato","year":"2007","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.toxicon.2013.06.004_bib10","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.jim.2003.10.011","article-title":"Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines","volume":"284","author":"Copeland","year":"2004","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.toxicon.2013.06.004_bib11","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.bbapap.2008.01.007","article-title":"Crystal structure of a myotoxic Asp49-phospholipase A2 with low catalytic activity: insights into Ca2+-independent catalytic mechanism","volume":"1784","author":"Correa","year":"2008","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.toxicon.2013.06.004_bib12","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1016\/j.toxicon.2009.12.018","article-title":"Immunome and venome of Bothrops jararacussu: a proteomic approach to study the molecular immunology of snake toxins","volume":"55","author":"Correa-Netto","year":"2010","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib13","doi-asserted-by":"crossref","first-page":"899","DOI":"10.2174\/092986609788923365","article-title":"Structural and pharmacological features of phospholipases A2 from snake venoms","volume":"16","author":"de Paula","year":"2009","journal-title":"Prot. Pept. Lett."},{"key":"10.1016\/j.toxicon.2013.06.004_bib14","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/S0041-0101(97)00111-6","article-title":"Cross-reactivity and heterologous neutralization of crotaline antivenoms used in Argentina","volume":"36","author":"de Roodt","year":"1998","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib15","first-page":"238","article-title":"Cross-neutralization of Bothrops jararacussu venom by heterologous antivenoms","volume":"59","author":"de Roodt","year":"1999","journal-title":"Medicina (B Aires)"},{"key":"10.1016\/j.toxicon.2013.06.004_bib16","series-title":"The PyMOL Molecular Graphics System","author":"DeLano","year":"2002"},{"key":"10.1016\/j.toxicon.2013.06.004_bib17","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1590\/S0036-46651992000200001","article-title":"A efic\u00e1cia do veneno antibotr\u00f3pico-crot\u00e1lico na neutraliza\u00e7\u00e3o das principais atividades do veneno de Bothrops jararacussu","volume":"34","author":"dos Santos","year":"1992","journal-title":"Rev. Inst. Med. Trop."},{"key":"10.1016\/j.toxicon.2013.06.004_bib18","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jsb.2010.03.019","article-title":"Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca2+-binding loop region for the catalytically inactive Lys49-PLA2s","volume":"171","author":"Fernandes","year":"2010","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.toxicon.2013.06.004_bib19","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0022-1759(02)00137-0","article-title":"The SPOT-synthesis technique. Synthetic peptide arrays on membrane supports-principles and applications","volume":"267","author":"Frank","year":"2002","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.toxicon.2013.06.004_bib20","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.biochi.2004.07.001","article-title":"Signal transduction pathway involved in the platelet aggregation induce by a D-49 phospholipases A2 isolated from Bothrops jararacussu snake venom","volume":"86","author":"Fully","year":"2004","journal-title":"Biochimie"},{"key":"10.1016\/j.toxicon.2013.06.004_bib21","series-title":"The Proteomics Protocols Handbook","first-page":"571","article-title":"Protein identification and analysis tools on the ExPASy server","author":"Gasteiger","year":"2005"},{"key":"10.1016\/j.toxicon.2013.06.004_bib22","series-title":"Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism","first-page":"321","article-title":"Phospholipase A2 myotoxins from Bothrops snake venoms","author":"Guti\u00e9rrez","year":"1997"},{"key":"10.1016\/j.toxicon.2013.06.004_bib23","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1021\/pr9009518","article-title":"Impact of regional variation in Bothrops asper snake venom on the design of antivenoms: integrating antivenomics and neutralization approaches","volume":"9","author":"Guti\u00e9rrez","year":"2010","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.toxicon.2013.06.004_bib24","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.copbio.2007.05.006","article-title":"Functional peptide arrays for high-throughput chemical biology based applications","volume":"18","author":"Henderson","year":"2007","journal-title":"Curr. Opin. Biotechnol."},{"key":"10.1016\/j.toxicon.2013.06.004_bib25","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.biochi.2006.10.010","article-title":"Purification and partial characterization of two phospholipases A2 from Bothrops leucurus (white tailed-jararaca) snake venom","volume":"89","author":"Higuchi","year":"2007","journal-title":"Biochimie"},{"key":"10.1016\/j.toxicon.2013.06.004_bib26","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1146\/annurev.pa.20.040180.001515","article-title":"Effects and mechanisms of polypeptide neurotoxins that act presynaptically","volume":"20","author":"Howard","year":"1980","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.toxicon.2013.06.004_bib27","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0003-9861(90)90266-2","article-title":"The amino acid sequence of a myotoxic phospholipase from the venom Bothrops asper","volume":"278","author":"Kaiser","year":"1990","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.toxicon.2013.06.004_bib28","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.biochi.2004.02.002","article-title":"Analysis of Bothrops jararacussu venomous gland transcriptome focusing on structural and functional aspects: I-gene expression profile of highly expressed phospholipases A2","volume":"86","author":"Kashima","year":"2004","journal-title":"Biochimie"},{"key":"10.1016\/j.toxicon.2013.06.004_bib29","first-page":"895","article-title":"Myotoxicity and physiological effects of three Trimeresurus flavoviridis phospholipases A2","volume":"28","author":"Kihara","year":"1992","journal-title":"Biochim. Int."},{"key":"10.1016\/j.toxicon.2013.06.004_bib30","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/0041-0101(86)90173-X","article-title":"Structure-function relationships of phospholipases. I: prediction of presynaptic neurotoxicity","volume":"24","author":"Kini","year":"1986","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib31","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0022-2836(82)90515-0","article-title":"A simple method for displaying the hydropathic character of a protein","volume":"157","author":"Kyte","year":"1982","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.toxicon.2013.06.004_bib32","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.toxicon.2012.05.028","article-title":"Identification of linear B-cell epitopes on myotoxin II, a Lys49-phospholipase A2 homologue from Bothrops asper snake venom","volume":"60","author":"Lomonte","year":"2012","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib33","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/0006-2952(94)90525-8","article-title":"Neutralization of the cytolytic and myotoxic activities of phospholipases A2 from Bothrops asper snake venom by glycosamineglycans of the heparin\/heparan sulfate family","volume":"47","author":"Lomonte","year":"1994","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.toxicon.2013.06.004_bib34","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.toxicon.2003.11.008","article-title":"An overview of lysine-49 phospholipase A2 myotoxins from crotalid snake venoms and their structural determinants of myotoxic action","volume":"42","author":"Lomonte","year":"2003","journal-title":"Toxicon"},{"issue":"16","key":"10.1016\/j.toxicon.2013.06.004_bib35","first-page":"24","article-title":"Synthetic peptides derived from the C-terminal region of Lys49 phospholipase A2 homologues from viperidae snake venoms: biomimetic activities and potential applications","volume":"28","author":"Lomonte","year":"2010","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.toxicon.2013.06.004_bib36","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.bbrc.2004.08.046","article-title":"Crystal structure of an acidic platelet aggregation inhibitor and hypotensive phospholipase A2 in the monomeric and dimeric states: insights into its oligomeric state","volume":"323","author":"Magro","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.toxicon.2013.06.004_bib37","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1107\/S0907444905029598","article-title":"Structure of BthA-I complexed with p-bromophenacyl bromide: possible correlations with lack of pharmacological activity","volume":"12","author":"Magro","year":"2005","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.toxicon.2013.06.004_bib38","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1007\/s00018-008-8113-3","article-title":"Cellular pathology induced by snake venom phospholipase A2 myotoxins and neurotoxins: common aspects of their mechanisms of action","volume":"65","author":"Montecucco","year":"2008","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.toxicon.2013.06.004_bib39","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.toxicon.2006.10.011","article-title":"Interfacial surface charge and free accessibility to the PLA2-active site-like region are essential requirements for the activity of Lys49-PLA2 homologues","volume":"49","author":"Murakami","year":"2007","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib40","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1006\/jmbi.2000.4042","article-title":"T-Coffee: a novel method for fast and accurate multiple sequence alignment","volume":"302","author":"Notredame","year":"2000","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.toxicon.2013.06.004_bib41","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.toxicon.2009.04.004","article-title":"Commercial monovalent antivenoms in Australia are polyvalent","volume":"54","author":"O'Leary","year":"2009","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib42","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0079-6603(08)61036-3","article-title":"Molecular evolution of snake toxins: is the functional diversity of snake toxins associated with a mechanism of accelerated evolution?","volume":"59","author":"Ohno","year":"1998","journal-title":"Prog. Nucleic Acid Res. Mol. Biol."},{"key":"10.1016\/j.toxicon.2013.06.004_bib43","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1016\/S0041-0101(01)00107-6","article-title":"Neutralization of the pharmacological effects of bothropstoxin-I from Bothrops jararacussu (jararacu\u00e7u) venom by crotoxin antiserum and heparin","volume":"39","author":"Oshima-Franco","year":"2001","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib44","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/j.toxicon.2008.10.002","article-title":"Interspecific variation in venom composition and toxicity of Brazilian snakes from Bothrops genus","volume":"52","author":"Queiroz","year":"2008","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib45","doi-asserted-by":"crossref","first-page":"11627","DOI":"10.1016\/S0021-9258(17)39077-4","article-title":"A comparison of the crystal structures of phospholipase A2 from bovine pancreas and Crotalus atrox","volume":"260","author":"Renetseder","year":"1985","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.toxicon.2013.06.004_bib46","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/j.bbalip.2006.07.011","article-title":"The phospholipase A2 superfamily and its group numbering system","volume":"1761","author":"Schaloske","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.toxicon.2013.06.004_bib47","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1016\/S0041-0101(96)00111-0","article-title":"Sequence analysis of Lys49 phospholipase A2 myotoxins","volume":"34","author":"Selistre-de-Araujo","year":"1996","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib48","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.toxicon.2003.11.004","article-title":"Chemical modifications of phospholipases A2 from snake venoms: effects on catalytic and pharmacological properties","volume":"42","author":"Soares","year":"2003","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2013.06.004_bib49","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1006\/abbi.2000.2244","article-title":"Dissociation of enzymatic and pharmacological properties of piratoxins-I and -III, two myotoxic phospholipases A2 from Bothrops pirajai snake venom","volume":"387","author":"Soares","year":"2001","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.toxicon.2013.06.004_bib50","series-title":"Chromatography-the Most Versatile Method of Chemical Analysis","first-page":"1","article-title":"Purification of phospholipases A2 from American snake venoms","author":"St\u00e1beli","year":"2012"},{"key":"10.1016\/j.toxicon.2013.06.004_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00204-011-0665-6","article-title":"Molecular characterization of an acidic phospholipase A2 from Bothrops pirajai snake venom: synthetic C-terminal peptide identifies its antiplatelet region","volume":"85","author":"Teixeira","year":"2011","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.toxicon.2013.06.004_bib52","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1111\/j.1742-4658.2006.05598.x","article-title":"Sequences, geographic variations and molecular phylogeny of venom phospholipases and three finger toxins of eastern India Bungarus fasciatus and kinetic analyses of its Pro31 phospholipases A2","volume":"274","author":"Tsai","year":"2007","journal-title":"FEBS J."},{"key":"10.1016\/j.toxicon.2013.06.004_bib53","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1042\/bj3620089","article-title":"Active site mutagenesis of a Lys49-phospholipase A2: biological and membrane-disrupting activities in the absence of catalysis","volume":"362","author":"Ward","year":"2002","journal-title":"Biochem. J."},{"key":"10.1016\/j.toxicon.2013.06.004_bib54","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.toxicon.2004.05.029","article-title":"Comparison of the neurotoxic and myotoxic effects of Brazilian Bothrops venoms and their neutralization by commercial antivenom","volume":"44","author":"Zamun\u00e9r","year":"2004","journal-title":"Toxicon"}],"container-title":["Toxicon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010113002183?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010113002183?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T21:08:35Z","timestamp":1758575315000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041010113002183"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":54,"alternative-id":["S0041010113002183"],"URL":"https:\/\/doi.org\/10.1016\/j.toxicon.2013.06.004","relation":{},"ISSN":["0041-0101"],"issn-type":[{"value":"0041-0101","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Linear B-cell epitopes in BthTX-1, BthTX-II and BthA-1, phospholipase A2's from Bothrops jararacussu snake venom, recognized by therapeutically neutralizing commercial horse antivenom","name":"articletitle","label":"Article Title"},{"value":"Toxicon","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.toxicon.2013.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}