{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T20:00:20Z","timestamp":1791576020458,"version":"4.3.4"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,6,24]],"date-time":"2016-06-24T00:00:00Z","timestamp":1466726400000},"content-version":"vor","delay-in-days":297,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004933","name":"Instituto Nacional de Ci\u00eancia e Tecnologia em Toxinas","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004933","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Secretaria de Estado do Planejamento e Coordena\u00e7\u00e3o Geral"},{"name":"Conselho de Gest\u00e3o do Patrim\u00f4nio Gen\u00e9tico"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicon"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.toxicon.2015.06.011","type":"journal-article","created":{"date-parts":[[2015,6,19]],"date-time":"2015-06-19T08:54:17Z","timestamp":1434704057000},"page":"1-11","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"special_numbering":"C","title":["Biological characterization of the Amazon coral Micrurus spixii snake venom: Isolation of a new neurotoxic phospholipase A2"],"prefix":"10.1016","volume":"103","author":[{"given":"Angelo L.C.","family":"Terra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leandro S.","family":"Moreira-Dill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Sim\u00f5es-Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Roniele N.","family":"Monteiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter L.G.","family":"Cavalcante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcia","family":"Gallacci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neuza B.","family":"Barros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Nicolete","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina B.G.","family":"Teles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia S.M.","family":"Medeiros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando B.","family":"Zanchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana P.","family":"Zuliani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo A.","family":"Calderon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo G.","family":"St\u00e1beli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreimar M.","family":"Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1\u20132","key":"10.1016\/j.toxicon.2015.06.011_bib1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0014-5793(95)01543-4","article-title":"Characterization of multiple nicotinic acetylcholine receptor-binding proteins and phospholipases A2 from the venom of the coral snake Micrurus nigrocinctus","volume":"380","author":"Alape-Gir\u00f3n","year":"1996","journal-title":"FEBS Lett."},{"key":"10.1016\/j.toxicon.2015.06.011_bib2","first-page":"259","article-title":"Elapid venom toxins: multiple recruitments of ancient scaffolds","author":"Alape-Gir\u00f3n","year":"1999","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.toxicon.2015.06.011_bib3","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0041-0101(96)00036-0","article-title":"Phospholipase A2 \u2013 a structural review","volume":"8","author":"Arni","year":"1996","journal-title":"Toxicon"},{"issue":"4","key":"10.1016\/j.toxicon.2015.06.011_bib4","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.cell.2014.01.011","article-title":"X-ray structure of acid-sensing ion channel 1 \u2013 snake toxin complex reveals open state of a Na+-selective channel","volume":"156","author":"Baconguis","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.toxicon.2015.06.011_bib5","first-page":"155","article-title":"Mudan\u00e7as na classifica\u00e7\u00e3o de serpentes pe\u00e7onhentas brasileiras e suas implica\u00e7\u00f5es na literatura m\u00e9dica","volume":"81","author":"Bernarde","year":"2011","journal-title":"Gaz. M\u00e9d. Bahia"},{"key":"10.1016\/j.toxicon.2015.06.011_bib6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1590\/S0044-59672012000100008","article-title":"Serpentes pe\u00e7onhentas e ofidismo em Cruzeiro do Sul, Alto Juru\u00e1, Estado do Acre, Brasil","volume":"42","author":"Bernarde","year":"2012","journal-title":"Acta Amaz."},{"key":"10.1016\/j.toxicon.2015.06.011_bib7","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1078\/094471103322331458","article-title":"Cytotoxic activity of some lichen extracts on murine and human cancer cell lines","volume":"10","author":"B\u00e9zivin","year":"2003","journal-title":"Phytomedicine"},{"key":"10.1016\/j.toxicon.2015.06.011_bib8","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.bcp.2010.10.004","article-title":"\u03b1-Elapitoxin-Aa2a, a long-chain snake \u03b1-neurotoxin with potent actions on muscle (\u03b11)\u03b2\u03b3\u03b4 nicotinic receptors, lacks the classical high af\ufb01nity for neuronal \u03b1-7 nicotinic receptors","volume":"81","author":"Blacklow","year":"2011","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.toxicon.2015.06.011_bib9","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/0041-0101(75)90197-X","article-title":"Natural resistance of bovine animals to Micrurus nigrocinctus venom","volume":"13","author":"Bola\u00f1os","year":"1975","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2015.06.011_bib10","first-page":"18","article-title":"Proteolytic activity of Elapid and Viperid snake venoms and its implication to digestion","volume":"1","author":"Bottrall","year":"2010","journal-title":"J.\u00a0Venom Res."},{"key":"10.1016\/j.toxicon.2015.06.011_bib11","first-page":"38","article-title":"Observations on the isolated phrenic-nerve diaphragm preparation of the rat","volume":"1","author":"B\u00fclbring","year":"1946","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.toxicon.2015.06.011_bib12","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s10557-008-6132-9","article-title":"Phospholipase A2 biochemistry","volume":"1","author":"Burke","year":"2009","journal-title":"Cardiovasc Drugs Ther."},{"key":"10.1016\/j.toxicon.2015.06.011_bib13","first-page":"19","article-title":"Antitumoral activity of snake venom proteins: new trends in cancer therapy","author":"Calderon","year":"2014","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.toxicon.2015.06.011_bib14","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.jprot.2011.01.003","article-title":"Snake population venomics and antivenomics of Bothrops atrox: paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management","volume":"74","author":"Calvete","year":"2011","journal-title":"J.\u00a0Proteomics"},{"key":"10.1016\/j.toxicon.2015.06.011_bib15","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1006\/expr.1994.1098","article-title":"In\u00a0vitro development of infectious liver stages of P.\u00a0yoelii and P.\u00a0berghei malaria in human cell lines","volume":"79","author":"Calvo-Calle","year":"1994","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.toxicon.2015.06.011_bib16","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.3390\/toxins4121500","article-title":"In\u00a0vitro antiplasmodial activity of phospholipases A2 and a phospholipase homologue isolated from the venom of the snake Bothrops asper","volume":"4","author":"Castillo","year":"2012","journal-title":"Toxins"},{"key":"10.1016\/j.toxicon.2015.06.011_bib17","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.toxicon.2014.10.015","article-title":"Identification and characterization of B-cell epitopes of 3FTx and PLA2 toxins from Micrurus corallinus snake venom","volume":"93","author":"Castro","year":"2015","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2015.06.011_bib18","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.cbpb.2004.11.012","article-title":"Biological and enzymatic activities of Micrurus sp. (Coral) snake venoms","volume":"140","author":"Cecchini","year":"2005","journal-title":"Comp. Biochem. Physiol."},{"key":"10.1016\/j.toxicon.2015.06.011_bib19","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.toxicon.2012.04.332","article-title":"Maintaining coral snakes (Micrurus nigrocinctus, Serpentes: Elapidae) for venom production on an alternative fish-based diet","volume":"60","author":"Chac\u00f3n","year":"2012","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2015.06.011_bib20","first-page":"16","article-title":"Venomic analysis and evaluation of antivenom cross-reactivity of South American Micrurus species","volume":"616","author":"Ciscotto","year":"2011","journal-title":"J.\u00a0Proteomics"},{"key":"10.1016\/j.toxicon.2015.06.011_bib21","first-page":"765","article-title":"Preliminary X-ray crystallographic studies of BthTX-II, a myotoxic Asp49-phospholipase A2 with low catalytic activity from Bothrops jararacussu venom","volume":"62","author":"Corr\u00eaa","year":"2006","journal-title":"Acta Cryst."},{"key":"10.1016\/j.toxicon.2015.06.011_bib22","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1016\/j.jprot.2011.04.003","article-title":"Snake venomics and venom gland transcriptomic analysis of Brazilian coral snakes, Micrurus altirostris and M.\u00a0corallinus","volume":"74","author":"Corr\u00eaa-Netto","year":"2011","journal-title":"J.\u00a0Proteomics"},{"key":"10.1016\/j.toxicon.2015.06.011_bib23","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1016\/j.peptides.2008.05.021","article-title":"Myotoxic phospholipases A2 isolated from Bothrops brazili snake venom and synthetic peptides derived from their C-terminal region: cytotoxic effect on microorganism and tumor cells","volume":"29","author":"Costa","year":"2008","journal-title":"Peptides"},{"issue":"1","key":"10.1016\/j.toxicon.2015.06.011_bib24","first-page":"117","article-title":"Comparative chromatography of Brazilian coral snake (Micrurus) venoms","volume":"100","author":"Da Silva","year":"1991","journal-title":"Comp. Biochem. Physiol."},{"key":"10.1016\/j.toxicon.2015.06.011_bib25","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.toxicon.2005.07.016","article-title":"Pharmacological and structural characterization of a novel phospholipase A2 from Micrurus dumerilii carinicauda venom","volume":"46","author":"Dal Belo","year":"2005","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2015.06.011_bib26","first-page":"1552","article-title":"Neurotoxicity of coral snake phospholipases A2 in cultured rat hippocampal neurons","volume":"13","author":"De Carvalho","year":"2014","journal-title":"Brain Res."},{"issue":"3","key":"10.1016\/j.toxicon.2015.06.011_bib27","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0041-0101(03)00139-9","article-title":"Cloning and characterization of a basic phospholipase A2 homologue from Micrurus corallinus (coral snake) venom gland","volume":"42","author":"de Oliveira","year":"2003","journal-title":"Toxicon"},{"issue":"2","key":"10.1016\/j.toxicon.2015.06.011_bib28","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.toxicon.2011.11.009","article-title":"Myotoxicity and nephrotoxicity by Micrurus venoms in experimental envenomation","volume":"59","author":"de Roodt","year":"2012","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2015.06.011_bib29","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0022-1759(86)90368-6","article-title":"Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability","volume":"89","author":"Denizot","year":"1986","journal-title":"J.\u00a0Immunol. Methods"},{"key":"10.1016\/j.toxicon.2015.06.011_bib30","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.toxicon.2008.12.015","article-title":"Biochemical characterization of the Micrurus pyrrhocryptus venom","volume":"53","author":"Dokmetjian","year":"2009","journal-title":"Toxicon"},{"issue":"82","key":"10.1016\/j.toxicon.2015.06.011_bib31","article-title":"Characterization of a human coagulation factor Xa-binding site on Viperidae snake venom phospholipases A2 by affinity binding studies and molecular bioinformatics","volume":"7","author":"Faure","year":"2007","journal-title":"BMC Struct. Biol."},{"issue":"5","key":"10.1016\/j.toxicon.2015.06.011_bib32","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/0041-0101(94)00178-B","article-title":"The ability of specific antivenom and low temperature to inhibit the myotoxicity and neuromuscular block induced by Micrurus nigrocinctus venom","volume":"33","author":"Goularte","year":"1995","journal-title":"Toxicon"},{"issue":"2","key":"10.1016\/j.toxicon.2015.06.011_bib33","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0014-5793(72)80756-7","article-title":"Degradation of a specific 5 S RNA-23 S RNA-protein complex by pancreatic ribonuclease","volume":"24","author":"Gray","year":"1972","journal-title":"FEBS Lett."},{"key":"10.1016\/j.toxicon.2015.06.011_bib34","first-page":"1","article-title":"Pathogenesis of myonecrosis induced by coral snake (Micrurus nigrocinctus) venom in mice","volume":"67","author":"Guti\u00e9rrez","year":"1986","journal-title":"Br. J. Exp. Pathol."},{"key":"10.1016\/j.toxicon.2015.06.011_bib35","article-title":"Biochemical characterization and pharmacological properties of new basic PLA2 BrTX-I isolated from Bothrops roedingeri (Roedinger's Lancehead) Mertens, 1942, snake venom","volume":"13","author":"Heleno","year":"2013","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.toxicon.2015.06.011_bib36","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.3390\/toxins6113077","article-title":"PhTX-II a basic myotoxic phospholipase A2 from Porthidium hyoprora snake venom, pharmacological characterization and amino acid sequence by mass spectrometry","volume":"6","author":"Huancahuire-Vega","year":"2014","journal-title":"Toxins"},{"key":"10.1016\/j.toxicon.2015.06.011_bib37","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/j.1096-0031.2008.00237.x","article-title":"Phylogeny, biogeography and classification of the snake superfamily Elapoidea: a rapid radiation in the late Eocene","volume":"25","author":"Kelly","year":"2009","journal-title":"Cladistics"},{"issue":"5259","key":"10.1016\/j.toxicon.2015.06.011_bib38","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.toxicon.2015.06.011_bib39","doi-asserted-by":"crossref","first-page":"418","DOI":"10.2307\/3280287","article-title":"Synchronisatton of Plasmodlum falciparum erythrocytlc stages in culture","volume":"65","author":"Lambros","year":"1979","journal-title":"J.\u00a0Parasitol."},{"key":"10.1016\/j.toxicon.2015.06.011_bib40","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/1471-2164-10-112","article-title":"Transcriptomic basis for an antiserum against Micrurus corallinus (coral snake) venom","volume":"10","author":"Le\u00e3o","year":"2009","journal-title":"BMC Genomics"},{"key":"10.1016\/j.toxicon.2015.06.011_bib41","doi-asserted-by":"crossref","first-page":"3165","DOI":"10.1529\/biophysj.105.070987","article-title":"Domain-induced activation of human phospholipase A2 type IIA: local versus global lipid composition","volume":"90","author":"Leidy","year":"2006","journal-title":"Biophys. J."},{"issue":"2","key":"10.1016\/j.toxicon.2015.06.011_bib42","doi-asserted-by":"crossref","first-page":"266","DOI":"10.4269\/ajtmh.1999.61.266","article-title":"Comparative study on the ability of IgG and f(ab')2 antivenoms to neutralize lethal and myotoxic effects induced by Micrurus nigrocinctus (coral snake) venom","volume":"61","author":"Le\u00f3n","year":"1999","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"11","key":"10.1016\/j.toxicon.2015.06.011_bib43","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0378-8741(02)00005-3","article-title":"Antimalarial activity of medicinal plants used in traditional medicine in S. Tom\u00e9 and Pr\u00edncipe islands","volume":"8","author":"Madureira","year":"2002","journal-title":"J.\u00a0Ethnopharmacol."},{"key":"10.1016\/j.toxicon.2015.06.011_bib44","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0041-0101(02)00211-8","article-title":"Biological and immunochemical characterization of Micrurus altirostris venom and serum neutralization of its toxic activities","volume":"41","author":"Moraes","year":"2003","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2015.06.011_bib45","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.toxicon.2010.02.030","article-title":"Frontoxins, three-finger toxins from Micrurus frontalis venom, decrease miniature endplate potential amplitude at frog neuromuscular junction","volume":"56","author":"Moreira","year":"2010","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2015.06.011_bib46","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0065-2776(01)77017-4","article-title":"Diversity and regulatory functions of mammalian secretory phospholipases PLA2s","volume":"77","author":"Murakami","year":"2001","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.toxicon.2015.06.011_bib47","doi-asserted-by":"crossref","first-page":"2838","DOI":"10.1002\/elps.200305552","article-title":"Proteomics of snake venoms from Elapidae and Viperidae families by multidimensional chromatographic methods","volume":"24","author":"Nawarak","year":"2003","journal-title":"Electrophoresis"},{"key":"10.1016\/j.toxicon.2015.06.011_bib48","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1128\/AAC.46.6.1658-1664.2002","article-title":"Histidine-rich protein II: a novel approach to malaria drug sensitivity testing","volume":"46","author":"Noedl","year":"2002","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.toxicon.2015.06.011_bib49","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1006\/bbrc.1999.2033","article-title":"Cloning and characterization of an a-neurotoxin-type protein speci\ufb01c for the coral snake Micrurus corallinus","volume":"267","author":"Oliveira","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.toxicon.2015.06.011_bib50","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.brainresbull.2007.10.007","article-title":"Phospholipases A2 isolated from Micrurus lemniscatus coral snake venom: behavioral, electroencephalographic, and neuropathological aspects","volume":"75","author":"Oliveira","year":"2008","journal-title":"Brain Res. Bull."},{"issue":"2","key":"10.1016\/j.toxicon.2015.06.011_bib51","first-page":"97","article-title":"Antileishmanial activity of Polyalthia longifolia leaf extract on the in\u00a0vitro growth of Leishmania donovani promastigotes","volume":"5","author":"Pal","year":"2011","journal-title":"Glob. J. Pharmacol."},{"issue":"6","key":"10.1016\/j.toxicon.2015.06.011_bib52","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1590\/S0036-46652010000600009","article-title":"Envenomation by Micrurus coral snakes in the Brazilian Amazon region: report of two cases","volume":"52","author":"Pardal","year":"2010","journal-title":"Rev. Inst. Med. Trop."},{"issue":"7","key":"10.1016\/j.toxicon.2015.06.011_bib53","doi-asserted-by":"crossref","first-page":"21237","DOI":"10.1371\/journal.pone.0021237","article-title":"Antimalarial activity of potential inhibitors of Plasmodium falciparum lactate dehydrogenase enzyme selected by docking studies","volume":"6","author":"Penna-Coutinho","year":"2011","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.toxicon.2015.06.011_bib54","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1016\/S0022-2275(20)32226-4","article-title":"A\u00a0simple assay for a human serum phospholipase A2 that is associated with high-density lipoproteins","volume":"42","author":"Petrovic","year":"2001","journal-title":"J.\u00a0Lipid. Res."},{"key":"10.1016\/j.toxicon.2015.06.011_bib55","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1042\/bj1790603","article-title":"Purification and characterization of a phospholipase A2 from the venom of the coral snake, Micrurus fulvius microgalbineus (Brown and Smith)","volume":"179","author":"Possani","year":"1979","journal-title":"Biochem. J."},{"issue":"4","key":"10.1016\/j.toxicon.2015.06.011_bib56","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1085\/jgp.201210946","article-title":"Loop C and the mechanism of acetylcholine receptor-channel gating","volume":"141","author":"Purohit","year":"2013","journal-title":"J.\u00a0Gen. Physiol."},{"key":"10.1016\/j.toxicon.2015.06.011_bib57","series-title":"Snake Venoms Components with Antitumor Activity in Murine Melanoma Cells","author":"Queiroz","year":"2012"},{"key":"10.1016\/j.toxicon.2015.06.011_bib58","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.actatropica.2012.07.003","article-title":"Antiplasmodial effect of the venom of Crotalus durissus cumanensis, crotoxin complex and Crotoxin B","volume":"124","author":"Quintana","year":"2012","journal-title":"Acta Trop."},{"issue":"1","key":"10.1016\/j.toxicon.2015.06.011_bib59","article-title":"Micrurus spixii (Peruvian coral snake) venom \u2013 preliminar biochemical and enzimatic characterization","volume":"8","author":"Remuzgo","year":"2012","journal-title":"J.\u00a0Venom. Anim. Toxin."},{"key":"10.1016\/j.toxicon.2015.06.011_bib60","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.toxicon.2011.10.017","article-title":"Neuromuscular activity of the venoms of the Colombian coral snakes Micrurus dissoleucus and Micrurus mipartitus: an evolutionary perspective","volume":"59","author":"Renjifo","year":"2012","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2015.06.011_bib61","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.jprot.2011.09.003","article-title":"Proteomic and biological characterization of the venom of the redtail coral snake, Micrurus mipartitus (Elapidae), from Colombia and Costa Rica","volume":"75","author":"Rey-S\u00faarez","year":"2011","journal-title":"J.\u00a0Proteomics"},{"key":"10.1016\/j.toxicon.2015.06.011_bib62","doi-asserted-by":"crossref","first-page":"8","DOI":"10.2174\/092986609788923266","article-title":"Snake venom phospholipases A2: a new class of antitumor agents","volume":"16","author":"Rodrigues","year":"2009","journal-title":"Protein Pept. Lett."},{"key":"10.1016\/j.toxicon.2015.06.011_bib63","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1111\/j.1471-4159.2006.03965.x","article-title":"Presynaptic enzymatic neurotoxins","volume":"97","author":"Rossetto","year":"2006","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.toxicon.2015.06.011_bib64","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.toxicon.2011.04.020","article-title":"Hemostatic and toxinological diversities in venom of Micrurus tener tener, Micrurus fulvius fulvius and Micrurus isozonus coral snakes","volume":"58","author":"Salazar","year":"2011","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2015.06.011_bib65","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1388-1981(00)00105-0","article-title":"The expanding superfamily of phospholipase A2 enzymes: classification and characterization","volume":"1488","author":"Six","year":"2000","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.toxicon.2015.06.011_bib66","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1006\/abbi.1999.1492","article-title":"Structural and functional characterization of a myotoxin I from Bothrops moojeni (caissaca) snake venom","volume":"373","author":"Soares","year":"2000","journal-title":"Arch. Biochem. Biophys."},{"issue":"3","key":"10.1016\/j.toxicon.2015.06.011_bib67","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1371\/journal.pntd.0000622","article-title":"Diversity of Micrurus snake species related to their venom toxic effects and the prospective of antivenom neutralization","volume":"4","author":"Tanaka","year":"2010","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.toxicon.2015.06.011_bib68","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1126\/science.781840","article-title":"Human malaria parasites in continuous culture","volume":"193","author":"Trager","year":"1976","journal-title":"Science"},{"key":"10.1016\/j.toxicon.2015.06.011_bib69","first-page":"485","article-title":"Feeding behavior and venom toxicity of coral snake Micrurus nigrocinctus (Serpentes: Elapidae) on its natural prey in captivity","volume":"138","author":"Urdaneta","year":"2004","journal-title":"Comp. Biochem. Physiol."},{"issue":"12","key":"10.1016\/j.toxicon.2015.06.011_bib70","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0115428","article-title":"Inhibition of nicotinic acetylcholine receptors, a novel facet in the pleiotropic activities of snake venom phospholipases A2","volume":"9","author":"Vulfius","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.toxicon.2015.06.011_bib71","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0041-0101(71)90073-0","article-title":"Cardiovascular and muscular effects of venom from coral snake, Micrurus fulvius","volume":"9","author":"Weis","year":"1971","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2015.06.011_bib72","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s10867-013-9299-7","article-title":"Pyrazolo[3,4-d]pyrimidines as inhibitor of anti-coagulation and inflammation activities of phospholipase A2: insight from molecular docking studies","volume":"39","author":"Yadava","year":"2013","journal-title":"J.\u00a0Biol. Phys."},{"key":"10.1016\/j.toxicon.2015.06.011_bib73","article-title":"Antitumoral potential of Tunisian snake venoms secreted phospholipases A2","volume":"9","author":"Zouari-Kessentini","year":"2013","journal-title":"BioMed Res. Int."}],"container-title":["Toxicon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010115001580?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010115001580?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,14]],"date-time":"2022-05-14T05:54:19Z","timestamp":1652507659000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041010115001580"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":73,"alternative-id":["S0041010115001580"],"URL":"https:\/\/doi.org\/10.1016\/j.toxicon.2015.06.011","relation":{},"ISSN":["0041-0101"],"issn-type":[{"value":"0041-0101","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biological characterization of the Amazon coral Micrurus spixii snake venom: Isolation of a new neurotoxic phospholipase A2","name":"articletitle","label":"Article Title"},{"value":"Toxicon","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.toxicon.2015.06.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}