{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:50:27Z","timestamp":1792788627027,"version":"4.5.0"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Vicerrector\u00eda de Investigaci\u00f3n of Universidad de Costa RicaVicerrector\u00eda de Investigaci\u00f3n, Universidad de Costa Rica","award":["741-B3-017"],"award-info":[{"award-number":["741-B3-017"]}],"id":[{"id":"https:\/\/ror.org\/02yzgww51","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicon"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.toxicon.2016.06.018","type":"journal-article","created":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T22:58:44Z","timestamp":1467413924000},"page":"1-8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Development of a chicken-derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom"],"prefix":"10.1016","volume":"120","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5834-6341","authenticated-orcid":false,"given":"Diego","family":"Navarro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari\u00e1ngela","family":"Vargas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Herrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1lvaro","family":"Segura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aar\u00f3n","family":"G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauren","family":"Villalta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils","family":"Ram\u00edrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Mar\u00eda","family":"Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Le\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.toxicon.2016.06.018_bib1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1590\/S0036-46652014000100009","article-title":"Coral snake antivenom produced in chickens (Gallus domesticus)","volume":"56","author":"Aguilar","year":"2014","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"key":"10.1016\/j.toxicon.2016.06.018_bib2","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.toxlet.2012.02.001","article-title":"Solving the \u2019Brown snake paradox\u2019: In\u00a0vitro characterisation of Australasian snake presynaptic neurotoxin activity","volume":"210","author":"Barber","year":"2012","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.toxicon.2016.06.018_bib3","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/0041-0101(92)90046-8","article-title":"Comparison of the purity and efficacy of affinity purified avian antivenoms with commercial equine crotalid antivenoms","volume":"30","author":"Carroll","year":"1992","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib4","series-title":"The International Guiding Principles for Biomedical Research Involving Animals","author":"Council of International Organizations of Medical Sciences (CIOMS)","year":"1985"},{"key":"10.1016\/j.toxicon.2016.06.018_bib5","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1016\/S0041-0101(99)00118-X","article-title":"The effects of antivenom on the in\u00a0vitro neurotoxicity of venoms from the taipans Oxyuranus scutellatus, Oxyuranus microlepidotus and Oxyuranus scutellatus canni","volume":"37","author":"Crachi","year":"1999","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib6","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.vetimm.2009.12.011","article-title":"IgY: a promising antibody for use in immunodiagnostic and in immunotherapy","volume":"135","author":"da Silva","year":"2010","journal-title":"Vet. Immmunol. Immunopathol."},{"key":"10.1016\/j.toxicon.2016.06.018_bib7","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1136\/vr.143.21.579","article-title":"Development of snake antivenom antibodies in chickens and their purification from yolk","volume":"143","author":"de Almeida","year":"1998","journal-title":"Vet. Rec."},{"key":"10.1016\/j.toxicon.2016.06.018_bib8","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.toxicon.2008.05.022","article-title":"Development of process to produce polyvalent IgY antibodies anti-African snake venom","volume":"52","author":"de Almeida","year":"2008","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib9","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.toxicon.2014.07.021","article-title":"IgY pharmacokinetics in rabbits: implications for IgY use as antivenoms","volume":"90","author":"D\u00edaz","year":"2014","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib10","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0167-5699(81)90071-2","article-title":"The avian immune system","volume":"2","author":"Fleischer","year":"1981","journal-title":"Immunol. Today"},{"key":"10.1016\/j.toxicon.2016.06.018_bib11","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1432-1033.1976.tb10833.x","article-title":"Taipoxin, an extremely potent presynaptic neurotoxin from the venom of the Australian snake taipan (Oxyuranus s. scutellatus). Isolation, characterization, quaternary structure and pharmacological properties","volume":"68","author":"Fohlman","year":"1976","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.toxicon.2016.06.018_bib12","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/0014-5793(77)80726-6","article-title":"Taipoxin, an extremely potent presynaptic snake venom neurotoxin. Elucidation of the primary structure of the acidic carbohydrate-containing taipoxin subunit, a phospholipase homolog","volume":"84","author":"Fohlman","year":"1977","journal-title":"FEBS Lett."},{"key":"10.1016\/j.toxicon.2016.06.018_bib13","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/0041-0101(89)90096-2","article-title":"Comparative study on coagulant, defibrinating, fibrinolytic and fibrinogenolytic activities of Costa Rican crotaline snake venoms and their neutralization by a polyvalent antivenom","volume":"27","author":"Gen\u00e9","year":"1989","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib14","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S0021-9258(18)57021-6","article-title":"Determination of serum proteins by means of the Bi\u00fcret reaction","volume":"177","author":"Gornall","year":"1949","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.toxicon.2016.06.018_bib15","doi-asserted-by":"crossref","first-page":"721","DOI":"10.2165\/00003088-200342080-00002","article-title":"Pharmacokinetic-pharmacodynamic relationships of immunoglobulin therapy for envenomation","volume":"42","author":"Guti\u00e9rrez","year":"2003","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.toxicon.2016.06.018_bib16","doi-asserted-by":"crossref","first-page":"369","DOI":"10.2174\/187152811797200669","article-title":"Antivenoms for snakebite envenomings","volume":"10","author":"Guti\u00e9rrez","year":"2011","journal-title":"Inflamm. Allergy Drug Targets"},{"key":"10.1016\/j.toxicon.2016.06.018_bib17","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/j.1476-5381.1982.tb09191.x","article-title":"Myotoxic activity of the crude venom and the principal neurotoxin, taipoxin, of the Australian taipan, Oxyuranus scutellatus","volume":"76","author":"Harris","year":"1982","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.toxicon.2016.06.018_bib18","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.toxicon.2005.08.004","article-title":"Factors associated with adverse reactions induced by caprylic acid-fractionated whole IgG preparations: comparison between horse, sheep and camel IgGs","volume":"46","author":"Herrera","year":"2005","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib19","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1016\/j.jprot.2012.01.006","article-title":"Comparative proteomic analysis of the venom of the taipan snake, Oxyuranus scutellatus, from Papua New Guinea and Australia: role of neurotoxic and procoagulant effects in venom toxicity","volume":"75","author":"Herrera","year":"2012","journal-title":"J.\u00a0Proteomics"},{"key":"10.1016\/j.toxicon.2016.06.018_bib20","doi-asserted-by":"crossref","first-page":"887","DOI":"10.4269\/ajtmh.14-0333","article-title":"Antivenomic characterization of two antivenoms against the venom of the taipan, Oxyuranus scutellatus, from Papua New Guinea and Australia","volume":"91","author":"Herrera","year":"2014","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.toxicon.2016.06.018_bib21","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.toxlet.2015.11.020","article-title":"Neutralization of the neuromuscular inhibition of venom and taipoxin from the taipan (Oxyuranus scutellatus) by F(ab\u2019)2 and whole IgG antivenoms","volume":"241","author":"Herrera","year":"2016","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.toxicon.2016.06.018_bib22","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1038\/jcbfm.2010.220","article-title":"Animal research: reporting in\u00a0vivo experiments-The ARRIVE guidelines","volume":"31","author":"Kilkenny","year":"2011","journal-title":"J.\u00a0Cereb. Blood Flow Metab."},{"key":"10.1016\/j.toxicon.2016.06.018_bib23","doi-asserted-by":"crossref","first-page":"850","DOI":"10.5694\/j.1326-5377.1991.tb94066.x","article-title":"Taipan envenomation","volume":"155","author":"King","year":"1991","journal-title":"Med. J. Aust."},{"key":"10.1016\/j.toxicon.2016.06.018_bib24","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1016\/j.toxicon.2010.03.003","article-title":"Development of a sensitive enzyme immunoassay for measuring taipan venom in serum","volume":"55","author":"Kulawickrama","year":"2010","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib25","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.toxicon.2016.06.018_bib26","doi-asserted-by":"crossref","first-page":"525","DOI":"10.4269\/ajtmh.1995.52.525","article-title":"Snake bites by the Papuan taipan (Oxyuranus scutellatus canni): paralysis, hemostatic and electrocardiographic abnormalities, and effects of antivenom","volume":"52","author":"Lalloo","year":"1995","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.toxicon.2016.06.018_bib27","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/00001721-199502000-00011","article-title":"Coagulopathy following bites by the Papuan taipan (Oxyuranus scutellatus canni)","volume":"6","author":"Lalloo","year":"1995","journal-title":"Blood Coag. Fibrinolysis"},{"key":"10.1016\/j.toxicon.2016.06.018_bib28","doi-asserted-by":"crossref","first-page":"54","DOI":"10.5694\/j.1326-5377.1997.tb138772.x","article-title":"Severe envenomation by the taipan (Oxyuranus scutellatus)","volume":"167","author":"Lalloo","year":"1997","journal-title":"Med. J. Aust."},{"key":"10.1016\/j.toxicon.2016.06.018_bib29","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0147-9571(90)90088-B","article-title":"Chicken IgY: utilizing the evolutionary difference","volume":"13","author":"Larsson","year":"1990","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"10.1016\/j.toxicon.2016.06.018_bib30","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/j.trstmh.2008.04.038","article-title":"Human heterophilic antibodies against equine immunoglobulins: assessment of their role in the early adverse reactions to antivenom administration","volume":"102","author":"Le\u00f3n","year":"2008","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.toxicon.2016.06.018_bib31","doi-asserted-by":"crossref","first-page":"381","DOI":"10.2174\/187152811797200605","article-title":"Immune response towards snake venoms","volume":"10","author":"Le\u00f3n","year":"2011","journal-title":"Inflamm. Allergy Drug Targets"},{"key":"10.1016\/j.toxicon.2016.06.018_bib32","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.toxicon.2013.09.010","article-title":"Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms","volume":"76","author":"Le\u00f3n","year":"2013","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib33","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/S0041-0101(01)00258-6","article-title":"Development of viper-venom antibodies in chicken egg yolk and assay of their antigen binding capacity","volume":"40","author":"Maya","year":"2002","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib34","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/j.intimp.2008.03.017","article-title":"Studies on pharmacological effects of Russell\u2019s viper and Saw-scaled viper venom and its neutralization by chicken egg yolk antibodies","volume":"8","author":"Meenatchisundaram","year":"2008","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.toxicon.2016.06.018_bib35","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.toxicon.2008.04.179","article-title":"Neutralization of the pharmacological effects of Cobra and Krait venoms by chicken egg yolk antibodies","volume":"52","author":"Meenatchisundaram","year":"2008","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib36","first-page":"846","article-title":"Protective efficacy of immunoglobulins Y prepared against Cerastes cerastes snake venom in the Kingdom of Saudi Arabia","volume":"33","author":"Moussa","year":"2012","journal-title":"Saudi Med. J."},{"key":"10.1016\/j.toxicon.2016.06.018_bib37","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.dci.2012.12.003","article-title":"Avian IgY is selectively incorporated into the egg yolks of oocytes by discriminating Fc amino acid residues located on the C\u03c53\/C\u03c54 interface","volume":"39","author":"Murai","year":"2013","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.toxicon.2016.06.018_bib38","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0049-3848(92)90230-8","article-title":"Activation of human factor VII by the prothrombin activator from the venom of Oxyuranus scutellatus (Taipan snake)","volume":"65","author":"Nakagaki","year":"1992","journal-title":"Thromb. Res."},{"key":"10.1016\/j.toxicon.2016.06.018_bib39","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1111\/j.1471-4159.2009.06365.x","article-title":"Mass spectrometry analysis of the phospholipaseA2 activity of snake pre-synaptic neurotoxins in cultured neurons","volume":"111","author":"Paoli","year":"2009","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.toxicon.2016.06.018_bib40","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.toxicon.2007.06.017","article-title":"Anti-Echis carinatus venom antibodies from chicken egg yolk: isolation, purification and neutralization efficacy","volume":"50","author":"Paul","year":"2007","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib41","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.toxicon.2013.03.013","article-title":"Role of the animal model on the pharmacokinetics of equine-derived antivenoms","volume":"70","author":"Rojas","year":"2013","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib42","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0041-0101(94)90087-6","article-title":"Caprylic acid fractionation of hyperimmune horse plasma: description of a simple procedure for antivenom production","volume":"32","author":"Rojas","year":"1994","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib43","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.pep.2005.03.013","article-title":"Efficient production, purification, and application of egg yok antibodies against human HLA-A*0201 heavy chain and light chain (\u03b22m)","volume":"44","author":"Ruan","year":"2005","journal-title":"Protein Expr. Purif."},{"key":"10.1016\/j.toxicon.2016.06.018_bib44","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.toxicon.2015.09.027","article-title":"Evaluation of the preclinical efficacy of four antivenoms, distributed in sub-Saharan Africa, to neutralize the venom of the carpet viper, Echis ocellatus, from Mali, Cameroon and Nigeria","volume":"106","author":"S\u00e1nchez","year":"2015","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib45","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1177\/026119290503300208","article-title":"Chicken egg yolk antibodies (IgY-technology): a review of progress in production and use in research and human and veterinary medicine","volume":"33","author":"Schade","year":"2005","journal-title":"Altern. Lab. Anim."},{"key":"10.1016\/j.toxicon.2016.06.018_bib46","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.biologicals.2012.11.001","article-title":"Assessment of snake antivenom purity by comparing physicochemical and immunochemical methods","volume":"41","author":"Segura","year":"2013","journal-title":"Biologicals"},{"key":"10.1016\/j.toxicon.2016.06.018_bib47","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.toxicon.2007.06.009","article-title":"On the presence of antibodies against bovine, equine and poultry immunoglobulins in human IgG preparations, and its implications on antivenom production","volume":"51","author":"Sevcik","year":"2008","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2016.06.018_bib48","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/S0022-3476(61)80320-X","article-title":"The persistence in the human circulation of horse and human tetanus antitoxins","volume":"59","author":"Smolens","year":"1961","journal-title":"J.\u00a0Pediatr."},{"key":"10.1016\/j.toxicon.2016.06.018_bib49","doi-asserted-by":"crossref","first-page":"13258","DOI":"10.1016\/S0021-9258(18)69299-3","article-title":"Prothrombin activation by an activator from the venom of Oxyuranus scutellatus (Taipan snake)","volume":"261","author":"Speijer","year":"1986","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.toxicon.2016.06.018_bib50","first-page":"949","article-title":"Development of simple standard assay procedures for the characterization of snake venoms","volume":"61","author":"Theakston","year":"1983","journal-title":"Bull. World Health Org."},{"key":"10.1016\/j.toxicon.2016.06.018_bib51","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1053\/saep.2002.28216","article-title":"The avian antibody response","volume":"11","author":"Tizard","year":"2002","journal-title":"Seminars Avian Exot. Pet Med."},{"key":"10.1016\/j.toxicon.2016.06.018_bib52","doi-asserted-by":"crossref","first-page":"e1144","DOI":"10.1371\/journal.pntd.0001144","article-title":"Preclinical evaluation of caprylic acid-fractionated IgG antivenom for the treatment of Taipan (Oxyuranus scutellatus) envenoming in Papua New Guinea","volume":"5","author":"Vargas","year":"2011","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.toxicon.2016.06.018_bib53","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.intimp.2010.01.005","article-title":"Pharmacokinetics in rabbits and anti-sphingomyelinase D neutralizing power of Fab, F(ab\u2019)2, IgG and IgG(T) fragments from hyper immune equine plasma","volume":"10","author":"V\u00e1zquez","year":"2010","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.toxicon.2016.06.018_bib54","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/0167-5699(95)80008-5","article-title":"IgY: clues to the origins of modern antibodies","volume":"16","author":"Warr","year":"1995","journal-title":"Immunol. Today"},{"key":"10.1016\/j.toxicon.2016.06.018_bib55","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/S1074-7613(04)00113-X","article-title":"The chicken yolk sac IgY receptor, a functional equivalent of the mammalian MHC-related Fc receptor, is a phospholipase A2 receptor homolog","volume":"20","author":"West","year":"2004","journal-title":"Immunity"},{"key":"10.1016\/j.toxicon.2016.06.018_bib56","series-title":"WHO Guidelines for the Production Control and Regulation of Snake Antivenom Immunoglobulins","author":"World Health Organization (WHO)","year":"2010"},{"key":"10.1016\/j.toxicon.2016.06.018_bib57","first-page":"2734","article-title":"Study on development of Vipera lebetina snake antivenom in chicken egg yolk for passive immunization","volume":"11","author":"Zolfagharian","year":"2015","journal-title":"Hum. Vaccin. Immunother."}],"container-title":["Toxicon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010116301726?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010116301726?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,2]],"date-time":"2022-07-02T11:24:04Z","timestamp":1656761044000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041010116301726"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":57,"alternative-id":["S0041010116301726"],"URL":"https:\/\/doi.org\/10.1016\/j.toxicon.2016.06.018","relation":{},"ISSN":["0041-0101"],"issn-type":[{"value":"0041-0101","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development of a chicken-derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom","name":"articletitle","label":"Article Title"},{"value":"Toxicon","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.toxicon.2016.06.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}