{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T04:42:53Z","timestamp":1794026573559,"version":"4.8.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005942","name":"Funda\u00e7\u00e3o Butantan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005942","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018217","name":"Universidade Federal de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["1501\/04"],"award-info":[{"award-number":["1501\/04"]}],"id":[{"id":"10.13039\/100018217","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018798","name":"Instituto Butantan","doi-asserted-by":"publisher","award":["190\/04"],"award-info":[{"award-number":["190\/04"]}],"id":[{"id":"10.13039\/100018798","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicon"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.toxicon.2021.09.004","type":"journal-article","created":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T02:19:19Z","timestamp":1632709159000},"page":"123-131","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["The effects of Tityus bahiensis scorpion venom on the contractility of jejunum, vas deferens, and the aorta is differentially affected by tetrodotoxin"],"prefix":"10.1016","volume":"202","author":[{"given":"Bianca Serra","family":"Casasco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00facia","family":"Garcez-do-Carmo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaltino Marcelo","family":"Concei\u00e7\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.toxicon.2021.09.004_bib1","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1046\/j.1540-8167.2004.03277.x","article-title":"Potassium channels and membrane potential in the modulation of intracellular calcium in vascular endothelial cells","volume":"15","author":"Adams","year":"2004","journal-title":"J. Cardiovasc. Electrophysiol."},{"issue":"3","key":"10.1016\/j.toxicon.2021.09.004_bib2","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1042\/bj3130753","article-title":"Toxic peptides and genes encoding toxin gamma of Brazilian scorpion Tityus bahiensis and Tityus stigmurus","volume":"313","author":"Becerril","year":"1996","journal-title":"Biochem. J."},{"issue":"6","key":"10.1016\/j.toxicon.2021.09.004_bib3","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/S0041-0101(96)00198-5","article-title":"Toxins and genes isolated from scorpions of the genus Tityus","volume":"35","author":"Becerril","year":"1997","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2021.09.004_bib4","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3389\/fneur.2011.00071","article-title":"Simultaneous parasympathetic and sympathetic activation reveals altered autonomic control of heart rate, vascular tension, and epinephrine release in anesthetized hypertensive rats","volume":"2","author":"Berg","year":"2011","journal-title":"Front. Neurol."},{"key":"10.1016\/j.toxicon.2021.09.004_bib5","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.toxicon.2014.06.022","article-title":"Clinical consequences of Tityus bahiensis and Tityus serrulatus scorpion stings in the region of Campinas, southeastern Brazil","volume":"89","author":"Bucaretchi","year":"2014","journal-title":"Toxicon"},{"issue":"5\u20136","key":"10.1016\/j.toxicon.2021.09.004_bib6","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0361-9230(99)00103-3","article-title":"Purinergic co-transmitter","volume":"50","author":"Burnstock","year":"1999","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.toxicon.2021.09.004_bib7","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.coph.2003.08.001","article-title":"Cotransmission","volume":"4","author":"Burnstock","year":"2004","journal-title":"Curr. Opin. Pharmacol."},{"issue":"9\u201310","key":"10.1016\/j.toxicon.2021.09.004_bib8","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/S0300-9084(00)01174-3","article-title":"Molecular mechanisms of neurotoxin action on voltage-gated sodium channels","volume":"82","author":"Cest\u00e8le","year":"2000","journal-title":"Biochimie"},{"key":"10.1016\/j.toxicon.2021.09.004_bib9","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.neuropharm.2019.04.013","article-title":"Scorpion venom increases acetylcholine release by prolonging the duration of somatic nerve action potentials","volume":"153","author":"Colla\u00e7o","year":"2019","journal-title":"Neuropharmacology"},{"issue":"9","key":"10.1016\/j.toxicon.2021.09.004_bib10","doi-asserted-by":"crossref","first-page":"3315","DOI":"10.1007\/s00204-020-02799-y","article-title":"Neurotoxicity of Tityus bahiensis (brown scorpion) venom in sympathetic vas deferens preparations and neuronal cells","volume":"94","author":"Colla\u00e7o","year":"2020","journal-title":"Arch. Toxicol."},{"issue":"8","key":"10.1016\/j.toxicon.2021.09.004_bib11","doi-asserted-by":"crossref","first-page":"920","DOI":"10.2174\/092986609788923329","article-title":"Tityus serrulatus scorpion venom and toxins: an overview","volume":"16","author":"Cologna","year":"2009","journal-title":"Protein Pept. Lett."},{"issue":"4","key":"10.1016\/j.toxicon.2021.09.004_bib12","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/sj.bjp.0706062","article-title":"Selective release of ATP from sympathetic nerves of the rat vas deferens by the toxin TsTX-I from Brazilian scorpion Tityus serrulatus","volume":"144","author":"Concei\u00e7\u00e3o","year":"2005","journal-title":"Br. J. Pharmacol."},{"issue":"6 Pt 1","key":"10.1016\/j.toxicon.2021.09.004_bib13","doi-asserted-by":"crossref","first-page":"C1745","DOI":"10.1152\/ajpcell.1998.274.6.C1745","article-title":"Synergism between toxin-\u03b3 from Brazilian scorpion Tityus serrulatus and veratridine in chromaffin cells","volume":"274","author":"Concei\u00e7\u00e3o","year":"1998","journal-title":"Am. J. Physiol."},{"issue":"6","key":"10.1016\/j.toxicon.2021.09.004_bib14","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1590\/0037-8682-0237-2015","article-title":"Clinical update on scorpion envenoming","volume":"48","author":"Cupo","year":"2015","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"2 Pt 1","key":"10.1016\/j.toxicon.2021.09.004_bib15","doi-asserted-by":"crossref","first-page":"C361","DOI":"10.1152\/ajpcell.1993.264.2.C361","article-title":"Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion","volume":"264","author":"DeBin","year":"1993","journal-title":"Am. J. Physiol."},{"issue":"3","key":"10.1016\/j.toxicon.2021.09.004_bib16","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.reprotox.2009.04.008","article-title":"Effects of prenatal exposure to Tityus bahiensis scorpion venom on rat offspring development","volume":"28","author":"Dorce","year":"2009","journal-title":"Reprod. Toxicol."},{"issue":"1","key":"10.1016\/j.toxicon.2021.09.004_bib17","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1678-9199-20-4","article-title":"Mild reproductive effects of the Tityus bahiensis scorpion venom in rats","volume":"20","author":"Dorce","year":"2014","journal-title":"J. Venom. Anim. Toxins Incl. Trop. Dis."},{"key":"10.1016\/j.toxicon.2021.09.004_bib18","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.toxicon.2015.06.023","article-title":"Tityus bahiensis scorpion venom injected to dams during pregnancy affects some cytokines of fetuses","volume":"103","author":"Dorce","year":"2015","journal-title":"Toxicon"},{"issue":"8","key":"10.1016\/j.toxicon.2021.09.004_bib19","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/0041-0101(93)90253-F","article-title":"Peptide T, a novel bradykinin potentiator isolated from Tityus serrulatus scorpion venom","volume":"31","author":"Ferreira","year":"1993","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2021.09.004_bib20","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/978-1-4939-0897-4_3","article-title":"The enteric nervous system and gastrointestinal innervation: integrated local and central control","volume":"817","author":"Furness","year":"2014","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.toxicon.2021.09.004_bib21","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S0076-6879(99)94035-1","article-title":"Scorpion toxins as tools for studying potassium channels","volume":"294","author":"Garcia","year":"1999","journal-title":"Methods Enzymol."},{"issue":"33","key":"10.1016\/j.toxicon.2021.09.004_bib22","doi-asserted-by":"crossref","first-page":"21084","DOI":"10.1074\/jbc.273.33.21084","article-title":"Human saphenous vein endothelial cells express a tetrodotoxin-resistant, voltage-gated sodium current","volume":"273","author":"Gosling","year":"1998","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.toxicon.2021.09.004_bib23","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1053\/gast.2002.30346","article-title":"Sodium current in human jejunal circular smooth muscle cells","volume":"122","author":"Holm","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.toxicon.2021.09.004_bib24","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.neuropharm.2016.10.004","article-title":"Scorpion toxin peptide action at the ion channel subunit level","volume":"127","author":"Housley","year":"2017","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.toxicon.2021.09.004_bib25","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1056\/NEJMra1401108","article-title":"Scorpion envenomation","volume":"371","author":"Isbister","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.toxicon.2021.09.004_bib26","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.neuropharm.2017.09.025","article-title":"Arthropod toxins acting on neuronal potassium channels","volume":"127","author":"Jim\u00e9nez-Vargas","year":"2017","journal-title":"Neuropharmacology"},{"issue":"2","key":"10.1016\/j.toxicon.2021.09.004_bib27","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1476-5381.1976.tb07439.x","article-title":"Dual effect of alpha-adrenoceptor antagonists in rat isolated vas deferens","volume":"56","author":"Jurkiewicz","year":"1976","journal-title":"Br. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.toxicon.2021.09.004_bib28","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0041-0101(01)00202-1","article-title":"Neurotoxic effects of fractions isolated from Tityus bahiensis scorpion venom (Perty, 1834)","volume":"40","author":"Louren\u00e7o","year":"2002","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2021.09.004_bib29","doi-asserted-by":"crossref","first-page":"102676","DOI":"10.1016\/j.autneu.2020.102676","article-title":"Effect of Tityus serrulatus scorpion venom on isolated jejunum: a very useful tool to study the interaction between neurons in the enteric nervous system","volume":"227","author":"Louza","year":"2020","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.toxicon.2021.09.004_bib30","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.toxicon.2016.06.016","article-title":"Potassium channel blockers from the venom of the Brazilian scorpion Tityus serrulatus (Lutz and Mello, 1922)","volume":"119","author":"Martin-Eauclaire","year":"2016","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2021.09.004_bib31","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.reprotox.2015.12.008","article-title":"Effect of maternal exposure to Tityus bahiensis scorpion venom during lactation on the offspring of rats","volume":"59","author":"Martins Ado","year":"2016","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.toxicon.2021.09.004_bib32","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1023\/A:1025643030044","article-title":"sodium channel toxins and neurotransmitter release","volume":"28","author":"Massensini","year":"2003","journal-title":"Neurochem. Res."},{"issue":"2\u20133","key":"10.1016\/j.toxicon.2021.09.004_bib33","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0014-2999(99)00016-3","article-title":"Pharmacological evidence that neuropeptides mediate part of the actions of scorpion venom on the Guinea pig ileum","volume":"368","author":"Matos","year":"1999","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.toxicon.2021.09.004_bib34","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.toxicon.2017.11.005","article-title":"A comparative study of pathophysiological alterations in scorpionism induced by Tityus serrulatus and Tityus bahiensis venoms","volume":"141","author":"Miyamoto","year":"2018","journal-title":"Toxicon"},{"issue":"1","key":"10.1016\/j.toxicon.2021.09.004_bib35","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/s12640-009-9144-8","article-title":"Differential effects of Tityus bahiensis scorpion venom on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium currents","volume":"19","author":"Moraes","year":"2011","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.toxicon.2021.09.004_bib36","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1113\/jphysiol.1991.sp018797","article-title":"Sodium currents in smooth muscle cells freshly isolated from stomach fundus of the rat and ureter of the Guinea-pig","volume":"442","author":"Muraki","year":"1991","journal-title":"J. Physiol."},{"issue":"6","key":"10.1016\/j.toxicon.2021.09.004_bib37","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.toxicon.2006.01.015","article-title":"Moving pieces in a taxonomic puzzle: venom 2D-LC\/MS and data clustering analyses to infer phylogenetic relationships in some scorpions from the Buthidae family (Scorpiones)","volume":"47","author":"Nascimento","year":"2006","journal-title":"Toxicon"},{"issue":"3","key":"10.1016\/j.toxicon.2021.09.004_bib38","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.neulet.2009.08.006","article-title":"Central effects of Tityus serrulatus and Tityus bahiensis scorpion venoms after intraperitoneal injection in rats","volume":"463","author":"Nencioni","year":"2009","journal-title":"Neurosci. Lett."},{"issue":"8","key":"10.1016\/j.toxicon.2021.09.004_bib39","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/0041-0101(94)90377-8","article-title":"Antigenic cross-reactivity among the venoms from several species of Brazilian scorpions","volume":"32","author":"Nishikawa","year":"1994","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2021.09.004_bib40","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1254\/jjp.60.263","article-title":"Application of physiologically active substances isolated from natural resources to pharmacological studies","volume":"73","author":"Ohizumi","year":"1997","journal-title":"Jpn. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.toxicon.2021.09.004_bib41","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/bip.22748","article-title":"Chlorotoxin: structure, activity, and potential uses in cancer therapy","volume":"106","author":"Ojeda","year":"2016","journal-title":"Biopolymers"},{"issue":"2","key":"10.1016\/j.toxicon.2021.09.004_bib42","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0306-3623(89)90016-5","article-title":"Effects of the venom of the Brazilian scorpion Tityus serrulatus and two of its fractions on the isolated diaphragm of the rat","volume":"20","author":"Oliveira","year":"1989","journal-title":"Gen. Pharmacol."},{"issue":"1","key":"10.1016\/j.toxicon.2021.09.004_bib43","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1046\/j.1365-2680.1998.1810021.x","article-title":"Nitric oxide as a neuromodulator of sympathetic transmission in the rat vas deferens","volume":"18","author":"Postorino","year":"1998","journal-title":"J. Auton. Pharmacol."},{"key":"10.1016\/j.toxicon.2021.09.004_bib44","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.toxicon.2015.10.015","article-title":"Tityus serrulatus venom \u2013 a lethal cocktail","volume":"108","author":"Pucca","year":"2015","journal-title":"Toxicon"},{"key":"10.1016\/j.toxicon.2021.09.004_bib45","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.1523\/JNEUROSCI.23-07-02715.2003","article-title":"Selective expression of a persistent tetrodotoxin-resistant Na+ current and NaV1.9 subunit in myenteric sensory neurons","volume":"23","author":"Rugiero","year":"2003","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.toxicon.2021.09.004_bib46","first-page":"119","article-title":"Effects of tityustoxin on the rat isolated tail artery","volume":"35","author":"Savino","year":"1985","journal-title":"Acta Physiol. Pharmacol. Latinoam."},{"issue":"1","key":"10.1016\/j.toxicon.2021.09.004_bib47","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1540\/jsmr.37.9","article-title":"Difference in effects of stretch on depressive effect of endothelium-derived nitric oxide on noradrenaline and high-K+-induced contractions between the aorta from normotensive and spontaneously hypertensive rats","volume":"37","author":"Sekiguchi","year":"2001","journal-title":"J. Smooth Muscle Res."},{"issue":"3","key":"10.1016\/j.toxicon.2021.09.004_bib48","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1748-1716.1989.tb08571.x","article-title":"Basic features of an extracellular recording method to study secretion of a sympathetic co-transmitter, presumably ATP","volume":"135","author":"Stjarne","year":"1989","journal-title":"Acta Physiol. Scand."},{"issue":"4","key":"10.1016\/j.toxicon.2021.09.004_bib49","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1046\/j.1365-2680.1999.00136.x","article-title":"Modelling the changes due to the endothelium and hypertension in the alpha-adrenoceptor-mediated responses of rat aorta","volume":"19","author":"Tabernero","year":"1999","journal-title":"J. Auton. Pharmacol."},{"issue":"5","key":"10.1016\/j.toxicon.2021.09.004_bib50","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0041-0101(00)00200-2","article-title":"Evidence for a direct action of Tityus serrulatus scorpion venom on the cardiac muscle","volume":"39","author":"Teixeira","year":"2001","journal-title":"Toxicon"},{"issue":"3","key":"10.1016\/j.toxicon.2021.09.004_bib51","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/sj.bjp.0701623","article-title":"Effects of Tityus serrulatus scorpion venom on the rabbit isolated corpus cavernosum and the involvement of NANC nitrergic nerve fibres","volume":"123","author":"Teixeira","year":"1998","journal-title":"Br. J. Pharmacol."},{"issue":"38","key":"10.1016\/j.toxicon.2021.09.004_bib52","doi-asserted-by":"crossref","first-page":"26051","DOI":"10.1074\/jbc.M109.031724","article-title":"Isolation and characterization of a high affinity peptide inhibitor of ClC-2 chloride channels","volume":"284","author":"Thompson","year":"2009","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.toxicon.2021.09.004_bib53","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0300-9629(95)00096-P","article-title":"Tityus bahiensis toxin IV-5b selectively affects Na channel inactivation in chick dorsal root ganglion neurons","volume":"112","author":"Trequattrini","year":"1995","journal-title":"Comp. Biochem. Physiol."},{"issue":"1","key":"10.1016\/j.toxicon.2021.09.004_bib54","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1254\/jjp.88.9","article-title":"Role of perivascular sympathetic nerves and regional differences in the features of sympathetic innervation of the vascular system","volume":"88","author":"Tsuru","year":"2002","journal-title":"Jpn. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.toxicon.2021.09.004_bib55","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0014-2999(97)01172-2","article-title":"Evidence against nitrergic neuromodulation in the rat vas deferens","volume":"334","author":"Ventura","year":"1997","journal-title":"Eur. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.toxicon.2021.09.004_bib56","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.bbrc.2008.04.104","article-title":"Tityus serrulatus Hypotensins: a new family of peptides from scorpion venom","volume":"371","author":"Verano-Braga","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"14","key":"10.1016\/j.toxicon.2021.09.004_bib57","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/0024-3205(94)00240-1","article-title":"Evidence for participation of nitric oxide in excitatory neurotransmission in rat vas deferens","volume":"55","author":"Vladimirova","year":"1994","journal-title":"Life Sci."},{"issue":"12","key":"10.1016\/j.toxicon.2021.09.004_bib58","doi-asserted-by":"crossref","first-page":"11656","DOI":"10.1074\/jbc.M410987200","article-title":"Caveolae targeting and regulation of large-conductance Ca2+-activated K+ channels in vascular endothelial cells","volume":"280","author":"Wang","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.toxicon.2021.09.004_bib59","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1749-6632.1990.tb37681.x","article-title":"ATP as a cotransmitter","volume":"603","author":"Westfall","year":"1990","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"2","key":"10.1016\/j.toxicon.2021.09.004_bib60","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S1056-8719(01)00144-7","article-title":"Pharmacological techniques for the in vitro study of the vas deferens","volume":"45","author":"Westfall","year":"2001","journal-title":"J. Pharmacol. Toxicol. Methods"},{"key":"10.1016\/j.toxicon.2021.09.004_bib61","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/BF00374945","article-title":"Fast Na+ current in circular smooth muscle cells of the large intestine","volume":"423","author":"Xiong","year":"1993","journal-title":"Pfl\u00fcgers Archiv"}],"container-title":["Toxicon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010121002518?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041010121002518?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T21:20:01Z","timestamp":1758576001000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041010121002518"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":61,"alternative-id":["S0041010121002518"],"URL":"https:\/\/doi.org\/10.1016\/j.toxicon.2021.09.004","relation":{},"ISSN":["0041-0101"],"issn-type":[{"value":"0041-0101","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effects of Tityus bahiensis scorpion venom on the contractility of jejunum, vas deferens, and the aorta is differentially affected by tetrodotoxin","name":"articletitle","label":"Article Title"},{"value":"Toxicon","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.toxicon.2021.09.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}