{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T06:46:52Z","timestamp":1770965212307,"version":"3.50.1"},"reference-count":19,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicology Letters"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1016\/j.toxlet.2004.09.013","type":"journal-article","created":{"date-parts":[[2004,11,12]],"date-time":"2004-11-12T17:22:52Z","timestamp":1100280172000},"page":"161-170","source":"Crossref","is-referenced-by-count":22,"title":["Attenuation of CD95-induced apoptosis by inorganic mercury: caspase-3 is not a direct target of low levels of Hg2+"],"prefix":"10.1016","volume":"155","author":[{"suffix":"Jr.","given":"Michael J.","family":"McCabe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin G.","family":"Eckles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Langdon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas W.","family":"Clarkson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Whitekus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allen J.","family":"Rosenspire","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.toxlet.2004.09.013_bib1","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1146\/annurev.cellbio.15.1.269","article-title":"Biochemical pathways of caspase activation during apoptosis","volume":"15","author":"Budihardjo","year":"1999","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.toxlet.2004.09.013_bib2","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3109\/10408369708998098","article-title":"The toxicology of mercury","volume":"34","author":"Clarkson","year":"1997","journal-title":"Clin. Rev. Clin. Lab. Sci."},{"key":"10.1016\/j.toxlet.2004.09.013_bib3","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1146\/annurev.biochem.68.1.383","article-title":"Mammalian caspases: structure, activation, substrates, and functions during apoptosis","volume":"68","author":"Earnshaw","year":"1999","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.toxlet.2004.09.013_bib4","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1080\/15287397709529452","article-title":"Clinical toxicology of mercury","volume":"2","author":"Gerstner","year":"1977","journal-title":"J. Toxicol. Environ. Health"},{"key":"10.1016\/j.toxlet.2004.09.013_bib5","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1038\/35037728","article-title":"CD95's deadly mission in the immune system","volume":"407","author":"Krammer","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.toxlet.2004.09.013_bib6","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S1567-5769(01)00180-1","article-title":"Immunomodulation by metals","volume":"2","author":"Lawrence","year":"2002","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.toxlet.2004.09.013_bib7","first-page":"966","article-title":"Atomic absorption determination of total, inorganic, and organic mercury in blood","volume":"55","author":"Magos","year":"1972","journal-title":"J. Assoc. Off. Anal. Chem."},{"key":"10.1016\/j.toxlet.2004.09.013_bib8","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1080\/00039896.1989.9935897","article-title":"Mercury concentration in organs of contemporary Japanese","volume":"44","author":"Matsuo","year":"1989","journal-title":"Arch. Environ. Health"},{"key":"10.1016\/j.toxlet.2004.09.013_bib9","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S0041-008X(03)00159-5","article-title":"Inorganic mercury attenuates CD95-mediated apoptosis by interfering with formation of the death inducing signaling complex","volume":"190","author":"McCabe","year":"2003","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.toxlet.2004.09.013_bib10","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.4049\/jimmunol.152.3.1064","article-title":"Redox mechanism as alternative to ligand binding for receptor activation delivering disregulated cellular signals","volume":"152","author":"Nakashima","year":"1994","journal-title":"J. Immunol."},{"key":"10.1016\/j.toxlet.2004.09.013_bib11","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1101\/gad.1212404","article-title":"Exploiting different ways to die","volume":"18","author":"Nelson","year":"2004","journal-title":"Genes Dev."},{"key":"10.1016\/j.toxlet.2004.09.013_bib12","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/0378-4274(92)90232-9","article-title":"Thiol modification and cell signalling in chemical toxicity","volume":"64\u201365","author":"Nicotera","year":"1992","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.toxlet.2004.09.013_bib13","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1002\/art.10415","article-title":"Cell death, autoantigen cleavage, and autoimmunity","volume":"46","author":"Pollard","year":"2002","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.toxlet.2004.09.013_bib14","first-page":"421","article-title":"Effects of mercury on the immune system","volume":"34","author":"Pollard","year":"1997","journal-title":"Met. Ions Biol. Syst."},{"key":"10.1016\/j.toxlet.2004.09.013_bib15","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S0192-0561(98)00045-9","article-title":"Low levels of ionic mercury modulate protein tyrosine phosphorylation in lymphocytes","volume":"20","author":"Rosenspire","year":"1998","journal-title":"Int. J. Immunopharmacol."},{"key":"10.1016\/j.toxlet.2004.09.013_bib16","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.cellsig.2003.08.007","article-title":"Death receptor-induced cell killing","volume":"16","author":"Thorburn","year":"2004","journal-title":"Cell Signal."},{"key":"10.1016\/j.toxlet.2004.09.013_bib17","doi-asserted-by":"crossref","first-page":"7162","DOI":"10.4049\/jimmunol.162.12.7162","article-title":"Protection against CD95-mediated apoptosis by inorganic mercury in Jurkat T cells","volume":"162","author":"Whitekus","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.toxlet.2004.09.013_bib18","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1539\/joh1959.36.2_66","article-title":"Background levels of total mercury concentrations in blood and urine","volume":"36","author":"Yamamura","year":"1994","journal-title":"Sangyo Igaku"},{"key":"10.1016\/j.toxlet.2004.09.013_bib19","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/(SICI)1097-4644(199701)64:1<43::AID-JCB7>3.0.CO;2-#","article-title":"Proteases in Fas-mediated apoptosis","volume":"64","author":"Zhivotovsky","year":"1997","journal-title":"J. Cell Biochem."}],"container-title":["Toxicology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378427404004709?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378427404004709?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,30]],"date-time":"2023-04-30T05:34:22Z","timestamp":1682832862000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378427404004709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["S0378427404004709"],"URL":"https:\/\/doi.org\/10.1016\/j.toxlet.2004.09.013","relation":{},"ISSN":["0378-4274"],"issn-type":[{"value":"0378-4274","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]}}}