{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:05:48Z","timestamp":1787065548228,"version":"build-2736575974"},"reference-count":63,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Cariplo Foundation Rif. 2011\u20132096"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology Letters"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.toxlet.2014.11.021","type":"journal-article","created":{"date-parts":[[2014,11,22]],"date-time":"2014-11-22T00:42:42Z","timestamp":1416616962000},"page":"449-457","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["One-month persistence of inflammation and alteration of fibrotic marker and cytoskeletal proteins in rat kidney after Cd-doped silica nanoparticle instillation"],"prefix":"10.1016","volume":"232","author":[{"given":"Teresa","family":"Coccini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Barni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piercarlo","family":"Mustarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Locatelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Roda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.toxlet.2014.11.021_bib0005","first-page":"192","article-title":"Probing metabolic stability of CdSe nanoparticles: alkaline extraction of free cadmium from liver and kidney samples of rats exposed to CdSe nanoparticles","volume":"192","author":"Arslan","year":"2011","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0010","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1385\/BTER:97:3:249","article-title":"Immunohistochemical and ultrastructural changes in the renal cortex of cadmium-treated rats","volume":"97","author":"Asar","year":"2004","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0015","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1093\/ndt\/gfg231","article-title":"Glomerular epithelial\u2013mesenchymal transdifferentiation in pauci-immune crescentic glomerulonephritis","volume":"18","author":"Bariety","year":"2003","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0020","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.2337\/diab.42.11.1673","article-title":"Transforming growth factor-b1 enhances glomerular collagen synthesis in diabetic rats","volume":"42","author":"Bollinelli","year":"1993","journal-title":"Diabetes"},{"issue":"11","key":"10.1016\/j.toxlet.2014.11.021_bib0025","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1038\/nrneph.2010.120","article-title":"Renal fibrosis: novel insights into mechanisms and therapeutic targets","volume":"6","author":"Boor","year":"2010","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0030","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.toxlet.2009.04.017","article-title":"The impact of size on tissue distribution and elimination by single intravenous injection of silica nanoparticles","volume":"189","author":"Cho","year":"2009","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0035","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1021\/es062347t","article-title":"In vitro cytotoxicitiy of silica nanoparticles at high concentrations strongly depends on the metabolic activity type of the cell line","volume":"41","author":"Chang","year":"2007","journal-title":"Environ. Sci. Technol."},{"issue":"8","key":"10.1016\/j.toxlet.2014.11.021_bib0040","doi-asserted-by":"crossref","first-page":"566","DOI":"10.3109\/15376516.2013.803270","article-title":"Apoptosis induction and histological changes in rat kidney following Cd-doped silica nanoparticle exposure: evidence of persisting effects","volume":"23","author":"Coccini","year":"2013","journal-title":"Toxicol. Mech. Methods"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0045","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1007\/s11051-012-0925-2","article-title":"Gene expression profiling in rat kidney after intratracheal exposure to cadmium-doped nanoparticles","volume":"14","author":"Coccini","year":"2012","journal-title":"J. Nanopart. Res."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0050","first-page":"195","article-title":"Pulmonary toxicity of instilled cadmium-doped silica nanoparticles during acute and subacute stages in rats","volume":"28","author":"Coccini","year":"2013","journal-title":"Histol. Histopathol. Cell. Mol. Biol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0055","first-page":"883","article-title":"Intraluminal fibrosis induced unilaterally by lobar instillation of CdCl2 into the rat lung","volume":"137","author":"Damiano","year":"1990","journal-title":"Am. J. Pathol."},{"issue":"3","key":"10.1016\/j.toxlet.2014.11.021_bib0060","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/S0002-9440(10)63478-5","article-title":"Antisense oligonucleotides against thrombospondin-1 inhibit activation of TGF-beta in fibrotic renal disease in the rat in vivo","volume":"163","author":"Daniel","year":"2003","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0065","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/0041-008X(92)90141-E","article-title":"Stimulation of rat alveolar macrophage fibronectin release in a cadmium chloride model of lung injury and fibrosis","volume":"116","author":"Driscoll","year":"1992","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0070","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1681\/ASN.V7122495","article-title":"Molecular insights into renal interstitial fibrosis","volume":"7","author":"Eddy","year":"1996","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0075","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1080\/15287398109530012","article-title":"Critical concentrations of cadmium in human renal cortex: dose-effect studies in cadmium smelter workers","volume":"7","author":"Ellis","year":"1981","journal-title":"J. Toxicol. Environ. Health"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0080","first-page":"1726","article-title":"Cadmium bioavailability","volume":"42","author":"Fox","year":"1983","journal-title":"Fed. Proc."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0085","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.tox.2012.02.001","article-title":"The toxicological mode of action and the safety of synthetic amorphous silica \u2013 a nanostructured material","volume":"294","author":"Fruijtier-Polloth","year":"2012","journal-title":"Toxicology"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0090","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1016\/j.biomaterials.2012.12.043","article-title":"The absorption, distribution, excretion and toxicity of mesoporous silica nanoparticles in mice following different exposure routes","volume":"34","author":"Fu","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0095","first-page":"708","article-title":"Transforming growth factor-b as a treatment target in renal diseases","volume":"22","author":"Fukuda","year":"2009","journal-title":"J. Nephrol."},{"issue":"1","key":"10.1016\/j.toxlet.2014.11.021_bib0100","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1755-1536-7-4","article-title":"The extracellular matrix in the kidney: a source of novel non-invasive biomarkers of kidney fibrosis?","volume":"7","author":"Genovese","year":"2014","journal-title":"Fibrogenesis Tissue Repair"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0105","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1093\/ndt\/17.12.2145","article-title":"Transforming growth factor-b1 in the kidney and urine of patients with glomerular disease and proteinuria","volume":"17","author":"Goumenos","year":"2002","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0110","first-page":"89","article-title":"Correlation of parameters of cadmium exposure with onset of cadmium-induced nephropathy in rats","volume":"5","author":"Goyer","year":"1984","journal-title":"J. Environ. Pathol. Toxicol. Oncol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0115","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.jhazmat.2013.06.040","article-title":"In vivo biodistribution and synergistic toxicity of silica nanoparticles and cadmium chloride in mice","volume":"260","author":"Guo","year":"2013","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0120","doi-asserted-by":"crossref","first-page":"9597","DOI":"10.1021\/ac801882g","article-title":"In vivo study of biodistribution and urinary excretion of surface-modified silica nanoparticles","volume":"80","author":"He","year":"2008","journal-title":"Anal. Chem."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0125","doi-asserted-by":"crossref","first-page":"285103","DOI":"10.1088\/0957-4484\/21\/28\/285103","article-title":"Lung deposition and extrapulmonary translocation of nano-ceria after intratracheal instillation","volume":"21","author":"He","year":"2010","journal-title":"Nanotechnology"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0130","doi-asserted-by":"crossref","first-page":"4045","DOI":"10.1016\/j.biomaterials.2008.07.007","article-title":"The biocompatibility of mesoporous silicates","volume":"29","author":"Hudson","year":"2008","journal-title":"Biomaterials"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0135","doi-asserted-by":"crossref","first-page":"327","DOI":"10.5271\/sjweh.2404","article-title":"Biological half-time of cadmium in the blood of workers after cessation of exposure","volume":"9","author":"Jarup","year":"1983","journal-title":"Scand. J. Work Environ. Health"},{"issue":"1","key":"10.1016\/j.toxlet.2014.11.021_bib0140","first-page":"1","article-title":"Health effects of cadmium exposure \u2013 a review of the literature and a risk estimate","volume":"24","author":"Jarup","year":"1998","journal-title":"Scand. J. Work Environ. Health"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0145","series-title":"Comprehensive Toxicology\u2013Renal Toxicology","first-page":"81","article-title":"Mechanisms of toxicant-induced acute kidney injury","author":"Lash","year":"2010"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0150","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.bcp.2008.07.004","article-title":"Novel roles for ceramides, calpains and caspases in kidney proximal tubule cell apoptosis: lessons from in vitro cadmium toxicity studies","volume":"76","author":"Lee","year":"2008","journal-title":"Biochem. Pharmacol."},{"issue":"12","key":"10.1016\/j.toxlet.2014.11.021_bib0155","doi-asserted-by":"crossref","first-page":"8544","DOI":"10.1166\/jnn.2010.2690","article-title":"Systematic influence induced by 3nm titanium dioxide following intratracheal instillation of mice","volume":"10","author":"Li","year":"2010","journal-title":"J. Nanosci. Nanotechnol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0160","doi-asserted-by":"crossref","first-page":"4834","DOI":"10.1021\/ja910846q","article-title":"Impacts of mesoporous silica nanoparticle size, pore ordering, and pore integrity on hemolytic activity","volume":"132","author":"Lin","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0165","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1016\/j.biomaterials.2010.10.035","article-title":"Single and repeated dose toxicity of mesoporous hollow silica nanoparticles in intravenously exposed mice","volume":"32","author":"Liu","year":"2011","journal-title":"Biomaterials"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0170","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1016\/j.biomaterials.2011.12.008","article-title":"Pathological mechanisms of liver injury caused by continuous intraperitoneal injection of silica nanoparticles","volume":"33","author":"Liu","year":"2012","journal-title":"Biomaterials"},{"issue":"2","key":"10.1016\/j.toxlet.2014.11.021_bib0175","first-page":"203","article-title":"Histopathologic and immunohistochemical aspects of the renal parenchyma in patients with glomerulonephritis developed in locked-up spaces","volume":"49","author":"M\u0103l\u0103escu","year":"2008","journal-title":"Rom. J. Morphol. Embryol."},{"issue":"5","key":"10.1016\/j.toxlet.2014.11.021_bib0180","doi-asserted-by":"crossref","first-page":"267","DOI":"10.3109\/15376516.2010.484077","article-title":"Translocation and extra pulmonary toxicities of multi wall carbon nanotubes in rats","volume":"20","author":"Narsimha Reddy","year":"2010","journal-title":"Toxicol. Mech. Methods"},{"issue":"2","key":"10.1016\/j.toxlet.2014.11.021_bib0185","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/s007950070009","article-title":"Mesangial myofibroblastic transformation in steroid-dependent minimal change nephrotic syndrome","volume":"33","author":"Naruse","year":"2000","journal-title":"Med. Electron. Microsc."},{"issue":"6","key":"10.1016\/j.toxlet.2014.11.021_bib0190","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1681\/ASN.2007070744","article-title":"IL-6\/IL-6R axis plays a critical role in acute kidney injury","volume":"19","author":"Nechemia-Arbely","year":"2008","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0195","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1126\/science.1114397","article-title":"Toxic potential of materials at the nanolevel","volume":"311","author":"Nel","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0200","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1164\/ajrccm.164.9.2101036","article-title":"Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamster","volume":"164","author":"Nemmar","year":"2001","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0205","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0013-9351(86)80101-3","article-title":"Critical concentration of cadmium in kidney cortex in humans exposed to environmental cadmium","volume":"40","author":"Nogawa","year":"1986","journal-title":"Environ. Res."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0210","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1093\/occmed\/kqh052","article-title":"Chronic overexposure to cadmium fumes associated with IgA mesangial glomerulonephritis","volume":"54","author":"Nogu\u00e9","year":"2004","journal-title":"Occup. Med."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0215","series-title":"Handbook of Toxicology of Metals","article-title":"Cadmium","author":"Nordberg","year":"2007"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0220","series-title":"Cadmium in the Human Environment: Toxicity and Carcinogenicity","first-page":"189","article-title":"Pulmonary deposition, clearance and effects of inhaled soluble and insoluble cadmium compounds","author":"Oberd\u00f6rster","year":"1992"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0225","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1080\/00984100290071658","article-title":"Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats","volume":"65","author":"Oberd\u00f6rster","year":"2002","journal-title":"J. Toxicol. Environ. Health A"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0230","unstructured":"OECD, List of manufactured nanomaterials and list of end points for phase one of the sponsorship programme for the testing of manufactured nanomaterials: Revision, Organisation for Economic Cooperation and Development, Environment Directorate, Paris. Series on the Safety of Manufactured Nanomaterials No. 27. ENV\/JM\/MONO (2010) 46."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0235","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.tox.2012.05.010","article-title":"Implication of oxidative stress in size-dependent toxicity of silica nanoparticles in kidney cells","volume":"299","author":"Passagne","year":"2012","journal-title":"Toxicology"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0240","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0013-9351(81)90199-7","article-title":"In vivo measurement of liver and kidney cadmium in workers exposed to this metal: its significance with respect to cadmium in blood and urine","volume":"26","author":"Roels","year":"1981","journal-title":"Environ. Res."},{"issue":"7","key":"10.1016\/j.toxlet.2014.11.021_bib0245","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1080\/01926230601080502","article-title":"Translocation pathway of the intratracheally instilled ultrafine particles from the lung into blood circulation in the mouse","volume":"34","author":"Shimida","year":"2006","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0250","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1080\/08958370902942566","article-title":"Engineered nanoparticle respiratory exposure and potential risks for cardiovascular toxicity: predictive tests and biomarkers","volume":"21","author":"Simeonova","year":"2009","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0255","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.taap.2009.01.013","article-title":"Cadmium and cellular signaling cascades: to be or not to be?","volume":"238","author":"Th\u00e9venod","year":"2009","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0260","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.tox.2006.10.011","article-title":"Chronic exposure of mice to environmentally relevant, low doses of cadmium leads to early renal damage, not predicted by blood or urine cadmium levels","volume":"229","author":"Thijssen","year":"2007","journal-title":"Toxicology"},{"issue":"2\u20133","key":"10.1016\/j.toxlet.2014.11.021_bib0265","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.tox.2007.06.087","article-title":"Changes in expression of fibrotic markers and histopathological alterations in kidneys of mice chronically exposed to low and high Cd doses","volume":"238","author":"Thijssen","year":"2007","journal-title":"Toxicology"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0270","first-page":"229","article-title":"Renal tissue expression of epidermal growth factor receptor after ischemic tubular injury: an immunohistochemical study","volume":"2","author":"Toubeau","year":"1994","journal-title":"Exp. Nephrol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0275","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1177\/0192623311406930","article-title":"Spontaneous glomerulonephritis in Go\u00f6ttingen minipigs","volume":"39","author":"Vezzali","year":"2011","journal-title":"Toxicol. Pathol."},{"issue":"2","key":"10.1016\/j.toxlet.2014.11.021_bib0280","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s00418-005-0023-y","article-title":"Tubular cell proliferation in the healthy rat kidney","volume":"124","author":"Vogetseder","year":"2005","journal-title":"Histochem. Cell. Biol."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0285","unstructured":"World Health Organization (WHO). Cadmium: air quality guidelines, 2nd ed., Copenhagen, Denmark: World Health Organization, Regional Office for 2000 (Chapter 6.3)."},{"issue":"2","key":"10.1016\/j.toxlet.2014.11.021_bib0290","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/cr.2009.5","article-title":"TGF-beta-induced epithelial to mesenchymal transition","volume":"19","author":"Xu","year":"2009","journal-title":"Cell Res."},{"key":"10.1016\/j.toxlet.2014.11.021_bib0295","doi-asserted-by":"crossref","first-page":"3417","DOI":"10.1021\/la701688t","article-title":"Hollow silica nanocontainers as drug delivery vehicles","volume":"24","author":"Yang","year":"2008","journal-title":"Langmuir"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0300","doi-asserted-by":"crossref","first-page":"5717","DOI":"10.1021\/nn2013904","article-title":"Impact of silica nanoparticle design on cellular toxicity and hemolytic activity","volume":"5","author":"Yu","year":"2011","journal-title":"ACS Nano"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0305","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1021\/nn2043803","article-title":"Influence of geometry, porosity, and surface characteristics of silica nanoparticles on acute toxicity: their vasculature effect and tolerance threshold","volume":"6","author":"Yu","year":"2012","journal-title":"ACS Nano"},{"key":"10.1016\/j.toxlet.2014.11.021_bib0310","doi-asserted-by":"crossref","first-page":"15790","DOI":"10.1021\/ja304907c","article-title":"Processing pathway dependence of amorphous silica nanoparticle toxicity: colloidal vs pyrolytic","volume":"134","author":"Zhang","year":"2012","journal-title":"J. Am. Chem. Soc."},{"issue":"2","key":"10.1016\/j.toxlet.2014.11.021_bib0315","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1093\/toxsci\/kfn245","article-title":"Particokinetics and extrapulmonary translocation of intratracheally instilled ferric oxide nanoparticles in rats and the potential health risk assessment","volume":"107","author":"Zhu","year":"2009","journal-title":"Toxicol. Sci."}],"container-title":["Toxicology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378427414014738?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378427414014738?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T23:57:38Z","timestamp":1650671858000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378427414014738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":63,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["S0378427414014738"],"URL":"https:\/\/doi.org\/10.1016\/j.toxlet.2014.11.021","relation":{},"ISSN":["0378-4274"],"issn-type":[{"value":"0378-4274","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"One-month persistence of inflammation and alteration of fibrotic marker and cytoskeletal proteins in rat kidney after Cd-doped silica nanoparticle instillation","name":"articletitle","label":"Article Title"},{"value":"Toxicology Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.toxlet.2014.11.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}