{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:18:50Z","timestamp":1778631530719,"version":"3.51.4"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32301416"],"award-info":[{"award-number":["32301416"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["YZLVJFJH2022YXBS154"],"award-info":[{"award-number":["YZLVJFJH2022YXBS154"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology Letters"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.toxlet.2026.111843","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T15:59:16Z","timestamp":1769702356000},"page":"111843","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Maternal dibutyl benzene-1,2-dicarboxylate exposure accelerates bone marrow mesenchymal stem cells senescence to induce skeletal retardation in male offspring mice"],"prefix":"10.1016","volume":"417","author":[{"given":"Yao","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kehan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingzhu","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruicheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuyuan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.toxlet.2026.111843_bib1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1152\/physrev.00033.2015","article-title":"Estrogens and androgens in skeletal physiology and pathophysiology","volume":"97","author":"Almeida","year":"2017","journal-title":"Physiol. Rev."},{"issue":"1","key":"10.1016\/j.toxlet.2026.111843_bib2","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1080\/01926230490265894","article-title":"Male reproductive tract lesions at 6, 12, and 18 months of age following in utero exposure to di(n-butyl) phthalate","volume":"32","author":"Barlow","year":"2004","journal-title":"Toxicol. Pathol."},{"issue":"7","key":"10.1016\/j.toxlet.2026.111843_bib3","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1210\/en.2015-1936","article-title":"Prepubertal Di-n-Butyl phthalate exposure alters sertoli and leydig cell function and lowers bone density in adult male mice","volume":"157","author":"Bielanowicz","year":"2016","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.toxlet.2026.111843_bib4","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1111\/1541-4337.13140","article-title":"Occurrence of phthalates in different food matrices: a systematic review of the main sources of contamination and potential risks","volume":"22","author":"da Costa","year":"2023","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"10.1016\/j.toxlet.2026.111843_bib5","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/j.envpol.2018.03.059","article-title":"Microcystin-leucine arginine (MC-LR) induces bone loss and impairs bone micro-architecture by modulating host immunity in mice: implications for bone health","volume":"238","author":"Dar","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.toxlet.2026.111843_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106903","article-title":"Human health impacts of exposure to phthalate plasticizers: an overview of reviews","volume":"158","author":"Eales","year":"2022","journal-title":"Environ. Int."},{"issue":"12","key":"10.1016\/j.toxlet.2026.111843_bib7","article-title":"Update of the risk assessment of di-butylphthalate (DBP), butyl-benzyl-phthalate (BBP), bis(2-ethylhexyl)phthalate (DEHP), di-isononylphthalate (DINP) and di-isodecylphthalate (DIDP) for use in food contact materials","volume":"17","author":"Efsa Panel on","year":"2019","journal-title":"EFSA J."},{"issue":"18","key":"10.1016\/j.toxlet.2026.111843_bib8","doi-asserted-by":"crossref","first-page":"7731","DOI":"10.1021\/acs.est.3c10175","article-title":"Mitochondrial DNA stress-mediated health risk to dibutyl phthalate contamination on zebrafish (Danio rerio) at early life stage","volume":"58","author":"Fan","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.toxlet.2026.111843_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.157482","article-title":"Rosmarinic acid alleviates doxorubicin-induced cellular senescence and cardiotoxicity by targeting the 14-3-3\/Foxo1 signaling axis","volume":"148","author":"Fan","year":"2025","journal-title":"Phytomedicine"},{"issue":"7","key":"10.1016\/j.toxlet.2026.111843_bib10","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1093\/humrep\/deg273","article-title":"Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate","volume":"18","author":"Fisher","year":"2003","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.toxlet.2026.111843_bib11","doi-asserted-by":"crossref","first-page":"16022","DOI":"10.1038\/boneres.2016.22","article-title":"miR-23a\/b regulates the balance between osteoblast and adipocyte differentiation in bone marrow mesenchymal stem cells","volume":"4","author":"Guo","year":"2016","journal-title":"Bone Res."},{"key":"10.1016\/j.toxlet.2026.111843_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.reprotox.2013.01.001","article-title":"Medications as a potential source of exposure to phthalates among women of childbearing age","volume":"37","author":"Hern\u00e1ndez-D\u00edaz","year":"2013","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.toxlet.2026.111843_bib13","doi-asserted-by":"crossref","first-page":"6197","DOI":"10.2147\/IJN.S143598","article-title":"Maternal exposure to nanosized titanium dioxide suppresses embryonic development in mice","volume":"12","author":"Hong","year":"2017","journal-title":"Int. J. Nanomed."},{"issue":"1","key":"10.1016\/j.toxlet.2026.111843_bib14","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1186\/s13287-018-0995-x","article-title":"Osteogenesis and aging: lessons from mesenchymal stem cells","volume":"9","author":"Infante","year":"2018","journal-title":"Stem Cell Res. Ther."},{"issue":"5","key":"10.1016\/j.toxlet.2026.111843_bib15","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0890-6238(02)00033-3","article-title":"NTP center for the evaluation of risks to human reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di-n-butyl phthalate","volume":"16","author":"Kavlock","year":"2002","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.toxlet.2026.111843_bib16","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.omtm.2019.05.011","article-title":"Rapamycin rescues age-related changes in muscle-derived stem\/progenitor cells from progeroid mice","volume":"14","author":"Kawakami","year":"2019","journal-title":"Mol. Ther. Methods Clin. Dev."},{"issue":"1","key":"10.1016\/j.toxlet.2026.111843_bib17","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s11658-025-00731-9","article-title":"Cdkn1a silencing restores myoblast differentiation by inducing selective apoptosis in senescent cells","volume":"30","author":"Kim","year":"2025","journal-title":"Cell Mol. Biol. Lett."},{"issue":"1-3","key":"10.1016\/j.toxlet.2026.111843_bib18","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.tox.2004.06.013","article-title":"Diverse developmental toxicity of di-n-butyl phthalate in both sexes of rat offspring after maternal exposure during the period from late gestation through lactation","volume":"203","author":"Lee","year":"2004","journal-title":"Toxicology"},{"issue":"1","key":"10.1016\/j.toxlet.2026.111843_bib19","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1038\/s41467-017-01509-0","article-title":"Programmed cell senescence in skeleton during late puberty","volume":"8","author":"Li","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.toxlet.2026.111843_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113342","article-title":"Co-exposure of polystyrene microplastics and iron aggravates cognitive decline in aging mice via ferroptosis induction","volume":"233","author":"Liu","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"6","key":"10.1016\/j.toxlet.2026.111843_bib21","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.cell.2013.05.039","article-title":"The hallmarks of aging","volume":"153","author":"L\u00f3pez-Ot\u00edn","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.toxlet.2026.111843_bib22","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.toxlet.2023.01.009","article-title":"Environmentally relevant perinatal exposure to DBP accelerated spermatogenesis by promoting the glycolipid metabolism of Sertoli cells in male offspring mice","volume":"377","author":"Ma","year":"2023","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.toxlet.2026.111843_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.131540","article-title":"Maternal exposure to dibutyl phthalate regulates MSH6 crotonylation to impair homologous recombination in fetal oocytes","volume":"455","author":"Ma","year":"2023","journal-title":"J. Hazard. Mater."},{"issue":"29","key":"10.1016\/j.toxlet.2026.111843_bib24","doi-asserted-by":"crossref","first-page":"14892","DOI":"10.1021\/acs.est.5c01532","article-title":"Molecular mechanisms of premature hippocampal and hypothalamic senescence induced by maternal exposure to DBP in male offspring mice","volume":"59","author":"Ma","year":"2025","journal-title":"Environ. Sci. Technol."},{"issue":"10","key":"10.1016\/j.toxlet.2026.111843_bib25","doi-asserted-by":"crossref","first-page":"E1997","DOI":"10.1210\/jc.2014-2279","article-title":"Urinary phthalate metabolites and the risk of low bone mineral density and osteoporosis in older women","volume":"99","author":"Min","year":"2014","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.toxlet.2026.111843_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121217","article-title":"Polystyrene microplastics arrest skeletal growth in puberty through accelerating osteoblast senescence","volume":"322","author":"Pan","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.toxlet.2026.111843_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2024.154017","article-title":"Chronic exposure to polystyrene microplastics triggers osteoporosis by breaking the balance of osteoblast and osteoclast differentiation","volume":"510","author":"Pan","year":"2025","journal-title":"Toxicology"},{"key":"10.1016\/j.toxlet.2026.111843_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2025.126931","article-title":"Microcystin-LR facilitates pubertal bone retardation by interfering with glutamine metabolism to accelerate stem cell senescence through Hippo\/GLS pathway","volume":"383","author":"Pan","year":"2025","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.toxlet.2026.111843_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106683","article-title":"The early-life exposome and epigenetic age acceleration in children","volume":"155","author":"de Prado-Bert","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.toxlet.2026.111843_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.125808","article-title":"Effects of phthalate acid esters on zebrafish larvae: development and skeletal morphogenesis","volume":"246","author":"Pu","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.toxlet.2026.111843_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105023","article-title":"Prenatal exposure to phthalates and neurocognitive development in children at two years of age","volume":"131","author":"Qian","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.toxlet.2026.111843_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.163783","article-title":"Toxic effects of triphenyltin on the development of zebrafish (Danio rerio) embryos","volume":"885","author":"Qiao","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.toxlet.2026.111843_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2025.154187","article-title":"Insights into the molecular mechanisms underlying phthalates-induced nephrotoxicity","volume":"516","author":"Quasmi","year":"2025","journal-title":"Toxicology"},{"issue":"6","key":"10.1016\/j.toxlet.2026.111843_bib34","doi-asserted-by":"crossref","DOI":"10.3390\/nu12061744","article-title":"Fetal-maternal exposure to endocrine disruptors: correlation with diet intake and pregnancy outcomes","volume":"12","author":"Rolfo","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.toxlet.2026.111843_bib35","first-page":"223","article-title":"UV photofunctionalization promotes nano-biomimetic apatite deposition on titanium","volume":"11","author":"Saita","year":"2016","journal-title":"Int. J. Nanomed."},{"issue":"Pt A","key":"10.1016\/j.toxlet.2026.111843_bib36","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.envpol.2019.05.066","article-title":"Fine air pollution particles induce endothelial senescence via redox-sensitive activation of local angiotensin system","volume":"252","author":"Sharma","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.toxlet.2026.111843_bib37","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.reprotox.2016.12.003","article-title":"Maternal di-(2-ethylhexyl) phthalate exposure during pregnancy causes fetal growth restriction in a stage-specific but gender-independent manner","volume":"67","author":"Shen","year":"2017","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.toxlet.2026.111843_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.166846","article-title":"A global meta-analysis of phthalate esters in drinking water sources and associated health risks","volume":"903","author":"Vasseghian","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.toxlet.2026.111843_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.123192","article-title":"Prenatal exposure to environmental heavy metals and newborn telomere length: a systematic review and meta-analysis","volume":"343","author":"Wai","year":"2024","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.toxlet.2026.111843_bib40","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.684532","article-title":"Exposure to dibutyl phthalate and reproductive-related outcomes in animal models: evidence from rodents study","volume":"12","author":"Wang","year":"2021","journal-title":"Front. Physiol."},{"key":"10.1016\/j.toxlet.2026.111843_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2024.119483","article-title":"Emerging perfluoroalkyl substances retard skeletal growth by accelerating osteoblasts senescence via ferroptosis","volume":"258","author":"Wang","year":"2024","journal-title":"Environ. Res."},{"key":"10.1016\/j.toxlet.2026.111843_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.154437","article-title":"Maternal DBP exposure promotes synaptic formation in offspring by activating astrocytes via the AKT\/NF-kappaB\/IL-6\/JAK2\/STAT3 signaling pathway","volume":"829","author":"Xia","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.toxlet.2026.111843_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.154437","article-title":"Maternal DBP exposure promotes synaptic formation in offspring by activating astrocytes via the AKT\/NF-\u03baB\/IL-6\/JAK2\/STAT3 signaling pathway","volume":"829","author":"Xia","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"2","key":"10.1016\/j.toxlet.2026.111843_bib44","doi-asserted-by":"crossref","first-page":"84","DOI":"10.17691\/stm2021.13.2.10","article-title":"Endocrine disruptors as a new etiologic factor of bone tissue diseases (review)","volume":"13","author":"Yaglova","year":"2021","journal-title":"Sovrem. Tekhnologii Med."},{"issue":"1","key":"10.1016\/j.toxlet.2026.111843_bib45","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1007\/s00018-024-05443-5","article-title":"MAGL blockade alleviates steroid-induced femoral head osteonecrosis by reprogramming BMSC fate in rat","volume":"81","author":"Yang","year":"2024","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.toxlet.2026.111843_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.169918","article-title":"Chronic di(2-ethylhexyl) phthalate exposure at environmental-relevant doses induces osteoporosis by disturbing the differentiation of bone marrow mesenchymal stem cells","volume":"914","author":"Zhang","year":"2024","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.toxlet.2026.111843_bib47","doi-asserted-by":"crossref","first-page":"11720","DOI":"10.1038\/s41467-025-66935-x","article-title":"Elimination of a neutrophil Pad4 byproduct restores stem cell-mediated bone regeneration in hyperglycemia","volume":"16","author":"Zhang","year":"2025","journal-title":"Nat. Commun."},{"issue":"46","key":"10.1016\/j.toxlet.2026.111843_bib48","article-title":"Bmi-1 epigenetically orchestrates osteogenic and adipogenic differentiation of bone marrow mesenchymal stem cells to delay bone aging","volume":"11","author":"Zhao","year":"2024","journal-title":"Adv. Sci."},{"issue":"21","key":"10.1016\/j.toxlet.2026.111843_bib49","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242115772","article-title":"Molecular and cellular mechanisms of osteoporosis","volume":"24","author":"Zhivodernikov","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.toxlet.2026.111843_bib50","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1038\/s41392-023-01354-2","article-title":"OTUB1 promotes osteoblastic bone formation through stabilizing FGFR2","volume":"8","author":"Zhu","year":"2023","journal-title":"Signal Transduct. Target Ther."}],"container-title":["Toxicology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378427426000263?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378427426000263?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T23:54:10Z","timestamp":1778630050000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378427426000263"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":50,"alternative-id":["S0378427426000263"],"URL":"https:\/\/doi.org\/10.1016\/j.toxlet.2026.111843","relation":{},"ISSN":["0378-4274"],"issn-type":[{"value":"0378-4274","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal dibutyl benzene-1,2-dicarboxylate exposure accelerates bone marrow mesenchymal stem cells senescence to induce skeletal retardation in male offspring mice","name":"articletitle","label":"Article Title"},{"value":"Toxicology Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.toxlet.2026.111843","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111843"}}