{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T09:17:13Z","timestamp":1753521433181},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,3,20]],"date-time":"2016-03-20T00:00:00Z","timestamp":1458432000000},"content-version":"vor","delay-in-days":79,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology Reports"],"published-print":{"date-parts":[[2016]]},"DOI":"10.1016\/j.toxrep.2016.03.010","type":"journal-article","created":{"date-parts":[[2016,3,22]],"date-time":"2016-03-22T14:20:44Z","timestamp":1458656444000},"page":"401-404","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Does amikacin treatment cause subclinical hearing loss in patients with cystic fibrosis?"],"prefix":"10.1016","volume":"3","author":[{"given":"Fevzi","family":"Solmaz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ercan","family":"G\u00fcndo\u011fdu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davut","family":"Akduman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Haksever","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O\u011fuzhan","family":"Dikici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatih","family":"\u00dcnal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.toxrep.2016.03.010_bib0005","series-title":"Douglas and Bennett\u2019s Pennett\u2019s Principles and Practice of Infectious Diseases","first-page":"279","article-title":"Aminoglycosides","author":"Gilbert","year":"1995"},{"issue":"1","key":"10.1016\/j.toxrep.2016.03.010_bib0010","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1128\/AAC.41.1.95","article-title":"Synergism between tobramycin and ceftazidime against a resistant Pseudomonas aeruginosa strain, tested in an in vivo pharmacokinetic model","volume":"41","author":"den Hollander","year":"1997","journal-title":"Antimicrob. Agents Chemother."},{"issue":"4","key":"10.1016\/j.toxrep.2016.03.010_bib0015","first-page":"761","article-title":"Aminoglycoside penetration, inactivation and efficacy in cystic fibrosis","volume":"132","author":"Mendelman","year":"1985","journal-title":"Am. Rev. Respir. Dis."},{"issue":"5","key":"10.1016\/j.toxrep.2016.03.010_bib0020","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1001\/archotol.1994.01880290009002","article-title":"Ear disease in children with cystic fibrosis","volume":"120","author":"Haddad","year":"1994","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"issue":"3","key":"10.1016\/j.toxrep.2016.03.010_bib0025","first-page":"200","article-title":"Atteinte de la sphere ORL dans la mucoviscidose","volume":"107","author":"Denoyelle","year":"1990","journal-title":"Ann. Otolaryngol. Chir. Cervicofac."},{"key":"10.1016\/j.toxrep.2016.03.010_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0011-5029(93)90028-2","article-title":"Cystic fibrosis","volume":"39","author":"Aitken","year":"1993","journal-title":"Dis. Month"},{"issue":"2","key":"10.1016\/j.toxrep.2016.03.010_bib0035","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0165-5876(95)01321-0","article-title":"Auditory nerve\u2013brainstem responses in cystic fibrosis patients","volume":"35","author":"Ozcelik","year":"1996","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"issue":"3","key":"10.1016\/j.toxrep.2016.03.010_bib0040","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1121\/1.408162","article-title":"Measuring human cochlear traveling wave delay using distortion product emissions phase responses","volume":"94","author":"Kimberley","year":"1993","journal-title":"J. Acoust. Soc. Am."},{"issue":"5","key":"10.1016\/j.toxrep.2016.03.010_bib0045","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/00003446-199910000-00002","article-title":"Effects of chronic tobramycin treatment on distortion product otoacoustic emissions","volume":"20","author":"Katbamna","year":"1999","journal-title":"Ear Hear."},{"issue":"1","key":"10.1016\/j.toxrep.2016.03.010_bib0050","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.otohns.2009.03.020","article-title":"Sensorineural hearing loss in patients with cystic fibrosis","volume":"141","author":"Cheng","year":"2009","journal-title":"Otolaryngol. Head Neck Surg."},{"issue":"2","key":"10.1016\/j.toxrep.2016.03.010_bib0055","first-page":"577","article-title":"Absence of acute tobramycin ototoxicity in both once or twice daily treatment regimens in patients with cystic fibrosis","volume":"30","author":"Suryanarayanan","year":"2005","journal-title":"Clin. Otolaryngol."},{"issue":"9","key":"10.1016\/j.toxrep.2016.03.010_bib0060","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S0165-5876(03)00135-6","article-title":"The prevalence of neurosensorial hearing loss among cystic fibrosis patients from Hospital de Clinicas de Porto Alegre","volume":"67","author":"Piltcher","year":"2003","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"issue":"6","key":"10.1016\/j.toxrep.2016.03.010_bib0065","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/BF02961666","article-title":"Aminoglycoside-induced ototoxicity in patients with cystic fibrosis","volume":"160","author":"Mulherin","year":"1991","journal-title":"Irish J. Med. Sci."},{"issue":"5","key":"10.1016\/j.toxrep.2016.03.010_bib0070","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.ijporl.2010.01.021","article-title":"Hearing loss in cystic fibrosis","volume":"74","author":"Martins","year":"2010","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"issue":"July","key":"10.1016\/j.toxrep.2016.03.010_bib0075","article-title":"The role of routine hearing screening in children with cystic fibrosis on aminoglycosides: a systematic review","author":"Farzal","year":"2015","journal-title":"Laryngoscope"},{"issue":"2\u20133","key":"10.1016\/j.toxrep.2016.03.010_bib0080","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.tox.2008.04.015","article-title":"Aminoglycoside induced ototoxicity","volume":"249","author":"Guthrie","year":"2008","journal-title":"Toxicology"}],"container-title":["Toxicology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214750016300300?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214750016300300?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T17:52:39Z","timestamp":1567705959000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214750016300300"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":16,"alternative-id":["S2214750016300300"],"URL":"https:\/\/doi.org\/10.1016\/j.toxrep.2016.03.010","relation":{},"ISSN":["2214-7500"],"issn-type":[{"value":"2214-7500","type":"print"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Does amikacin treatment cause subclinical hearing loss in patients with cystic fibrosis?","name":"articletitle","label":"Article Title"},{"value":"Toxicology Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.toxrep.2016.03.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Published by Elsevier Ireland Ltd.","name":"copyright","label":"Copyright"}]}}