{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:30:13Z","timestamp":1760646613479},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,9]],"date-time":"2017-03-09T00:00:00Z","timestamp":1489017600000},"content-version":"vor","delay-in-days":67,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Grant-in-Aid for Research Activity Start-up","award":["16821327"],"award-info":[{"award-number":["16821327"]}]},{"name":"Promotion Plan for the Platform of Human Resource Development"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology Reports"],"published-print":{"date-parts":[[2017]]},"DOI":"10.1016\/j.toxrep.2017.03.003","type":"journal-article","created":{"date-parts":[[2017,3,10]],"date-time":"2017-03-10T21:40:56Z","timestamp":1489182056000},"page":"172-180","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Bortezomib alters sour taste sensitivity in mice"],"prefix":"10.1016","volume":"4","author":[{"given":"Akihiro","family":"Ohishi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Nishida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Miyamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mizuka","family":"Imai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryoko","family":"Nakanishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoko","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuki","family":"Nagasawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.toxrep.2017.03.003_bib0005","doi-asserted-by":"crossref","first-page":"4112","DOI":"10.1200\/JCO.2003.01.095","volume":"21","author":"Hesketh","year":"2003","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0010","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1056\/NEJMra0706547","article-title":"Chemotherapy-Induced nausea and vomiting","volume":"358","author":"Hesketh","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0015","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1634\/theoncologist.2009-0333","article-title":"Taste alterations in cancer patients receiving chemotherapy: a neglected side effect","volume":"15","author":"Zabernigg","year":"2010","journal-title":"Oncologist"},{"key":"10.1016\/j.toxrep.2017.03.003_bib0020","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/j.ijrobp.2006.10.046","article-title":"Does zinc sulfate prevent therapy-induced taste alterations in head and neck cancer patients? Results of phase III double-blind, placebo-controlled trial from the North Central Cancer Treatment Group (N01C4)","volume":"67","author":"Halyard","year":"2007","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0025","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.neuroscience.2011.07.006","article-title":"Cyclophosphamide-induced disruption of umami taste functions and taste epithelium","volume":"192","author":"Mukherjee","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.toxrep.2017.03.003_bib0030","doi-asserted-by":"crossref","first-page":"e61607","DOI":"10.1371\/journal.pone.0061607","article-title":"Pre-treatment with amifostine protects against cyclophosphamide-induced disruption of taste in mice","volume":"8","author":"Mukherjee","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.toxrep.2017.03.003_bib0035","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1248\/bpb.b15-00935","article-title":"Oxaliplatin alters expression of T1R2 receptor and sensitivity to sweet taste in rats","volume":"39","author":"Ohishi","year":"2016","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0040","doi-asserted-by":"crossref","first-page":"3234","DOI":"10.1158\/1535-7163.MCT-09-0239","article-title":"The relationship among tumor architecture, pharmacokinetics, pharmacodynamics, and efficacy of bortezomib in mouse xenograft models","volume":"8","author":"Williamson","year":"2009","journal-title":"Mol. Cancer Ther."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0045","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1056\/NEJMoa043445","article-title":"Bortezomib or high-dose dexamethasone for relapsed multiple myeloma","volume":"352","author":"Richardson","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0050","doi-asserted-by":"crossref","first-page":"5025","DOI":"10.1200\/JCO.2006.06.1853","article-title":"Randomized phase II study of bortezomib alone and bortezomib in combination with docetaxel in previously treated advanced non-small-cell lung cancer","volume":"24","author":"Fanucchi","year":"2006","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0055","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.expneurol.2010.02.006","article-title":"Neurophysiological, histological and immunohistochemical characterization of bortezomib-induced neuropathy in mice","volume":"223","author":"Bruna","year":"2010","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0060","doi-asserted-by":"crossref","first-page":"e72995","DOI":"10.1371\/journal.pone.0072995","article-title":"Bortezomib-induced painful peripheral neuropathy: an electrophysiological, behavioral, morphological and mechanistic study in the mouse","volume":"8","author":"Carozzi","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.toxrep.2017.03.003_bib0065","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.1200\/JCO.2004.02.106","article-title":"Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer","volume":"22","author":"Papandreou","year":"2004","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0070","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/j.1349-7006.2007.00638.x","article-title":"Phase I and II pharmacokinetic and pharmacodynamic study of the proteasome inhibitor bortezomib in Japanese patients with relapsed or refractory multiple myeloma","volume":"99","author":"Ogawa","year":"2008","journal-title":"Cancer Sci."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0075","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/chemse\/28.3.237","article-title":"Gurmarin suppression of licking responses to sweetener-quinine mixtures in C57BL mice","volume":"28","author":"Murata","year":"2003","journal-title":"Chem. Senses"},{"key":"10.1016\/j.toxrep.2017.03.003_bib0080","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1073\/pnas.0912048107","article-title":"Endocannabinoids selectively enhance sweet taste","volume":"107","author":"Yoshida","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0085","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1113\/jphysiol.2012.236604","article-title":"Taste responses in mice lacking taste receptor subunit T1R1","volume":"591","author":"Kusuhara","year":"2013","journal-title":"J. Physiol."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0090","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.neulet.2012.10.063","article-title":"Expression of equilibrative nucleoside transporter 1 in rat circumvallate papillae","volume":"533","author":"Nishida","year":"2013","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0095","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/j.1471-4159.2006.03842.x","article-title":"Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells","volume":"98","author":"Lopez-Jimenez","year":"2006","journal-title":"J. Neurochem."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0100","doi-asserted-by":"crossref","first-page":"12569","DOI":"10.1073\/pnas.0602702103","article-title":"Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor","volume":"103","author":"Ishimaru","year":"2006","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0105","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1038\/nature05084","article-title":"The cells and logic for mammalian sour taste detection","volume":"442","author":"Huang","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.toxrep.2017.03.003_bib0110","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/chemse\/bjm083","article-title":"The candidate sour taste receptor, PKD2L1, is expressed by type III taste cells in the mouse","volume":"33","author":"Kataoka","year":"2008","journal-title":"Chem. Senses"},{"key":"10.1016\/j.toxrep.2017.03.003_bib0115","doi-asserted-by":"crossref","first-page":"e20007","DOI":"10.1371\/journal.pone.0020007","article-title":"Sour taste responses in mice lacking PKD channels","volume":"6","author":"Horio","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.toxrep.2017.03.003_bib0120","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1038\/ncomms2257","article-title":"Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex","volume":"3","author":"Yu","year":"2012","journal-title":"Nat. Commun."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0125","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1182\/blood-2012-02-407999","article-title":"Cytotoxic effects of bortezomib in myelodysplastic syndrome\/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1","volume":"120","author":"Fang","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.toxrep.2017.03.003_bib0130","doi-asserted-by":"crossref","first-page":"35283","DOI":"10.1074\/jbc.M113.544171","article-title":"Agonist-promoted ubiquitination differentially regulates receptor trafficking of endothelin type A and type B receptors","volume":"289","author":"Terada","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0135","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/cne.1372","article-title":"Type III cells of rat taste buds: immunohistochemical and ultrastructural studies of neuron-specific enolase, protein gene product 9.5, and serotonin","volume":"440","author":"Yee","year":"2001","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0140","doi-asserted-by":"crossref","first-page":"6735","DOI":"10.1021\/bi960099f","article-title":"Substrate binding and catalysis by ubiquitin C-terminal hydrolases: identification of two active site residues","volume":"35","author":"Larsen","year":"1996","journal-title":"Biochemistry"},{"key":"10.1016\/j.toxrep.2017.03.003_bib0145","doi-asserted-by":"crossref","first-page":"3358","DOI":"10.1021\/bi972274d","article-title":"Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases","volume":"37","author":"Larsen","year":"1998","journal-title":"Biochemistry"},{"key":"10.1016\/j.toxrep.2017.03.003_bib0150","first-page":"R58","article-title":"Factors affecting the sensitivity of the lingual trigeminal nerve to acids","volume":"268","author":"Bryant","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0155","doi-asserted-by":"crossref","first-page":"E229","DOI":"10.1073\/pnas.1514282112","article-title":"The K+ channel KIR2: 1 functions in tandem with proton influx to mediate sour taste transduction","volume":"113","author":"Ye","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.toxrep.2017.03.003_bib0160","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1111\/j.1742-4658.2012.08566.x","article-title":"The response of PKD1L3\/PKD2L1 to acid stimuli is inhibited by capsaicin and its pungent analogs","volume":"279","author":"Ishii","year":"2012","journal-title":"FEBS J."}],"container-title":["Toxicology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214750017300136?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214750017300136?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T22:50:31Z","timestamp":1719096631000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214750017300136"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":32,"alternative-id":["S2214750017300136"],"URL":"https:\/\/doi.org\/10.1016\/j.toxrep.2017.03.003","relation":{},"ISSN":["2214-7500"],"issn-type":[{"value":"2214-7500","type":"print"}],"subject":[],"published":{"date-parts":[[2017]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bortezomib alters sour taste sensitivity in mice","name":"articletitle","label":"Article Title"},{"value":"Toxicology Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.toxrep.2017.03.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Authors. Published by Elsevier Ireland Ltd.","name":"copyright","label":"Copyright"}]}}