{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T17:35:02Z","timestamp":1773336902974,"version":"3.50.1"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006021","name":"General Directorate of Armaments","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006021","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100016398","name":"Minist\u00e8re des Arm\u00e9es","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016398","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology Reports"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.toxrep.2025.102159","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T02:50:59Z","timestamp":1762311059000},"page":"102159","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Predicting the severity of eye damage induced in rabbits after sulfur mustard vapor exposure"],"prefix":"10.1016","volume":"15","author":[{"given":"Fanny","family":"Caffin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0430-3992","authenticated-orcid":false,"given":"Fanny","family":"Gros-D\u00e9sormeaux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Igert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e9mence","family":"Dumas-Croset","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara-Lou","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"El\u00e9ana","family":"Navarre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Caron","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Pi\u00e9rard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.toxrep.2025.102159_bib1","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.toxlet.2019.12.001","article-title":"Recent sulfur mustard attacks in Middle East and experience of health professionals","volume":"320","author":"Sezigen","year":"2020","journal-title":"Toxicol. Lett."},{"issue":"7","key":"10.1016\/j.toxrep.2025.102159_bib2","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1007\/s00204-019-02461-2","article-title":"Forensic evidence of sulfur mustard exposure in real cases of human poisoning by detection of diverse albumin-derived protein adducts","volume":"93","author":"John","year":"2019","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.toxrep.2025.102159_bib3","unstructured":"OPCW. United Kingdom of Great Britain and Northern Ireland joint statement of 8 november 2017 on Syria chemical weapons by Boris Johnson, foreign secretary of the United Kingdom, Jean-Yves Le Drian, foreign minister of France, Sigmar Gabriel, foreign minister of Germany and Rex Tillerson, secretary of state of the United States. 9 November 2017."},{"issue":"3","key":"10.1016\/j.toxrep.2025.102159_bib4","first-page":"11","article-title":"Sulfur mustard effects on mental health and quality-of-life: a review","volume":"8","author":"Razavi","year":"2014","journal-title":"Iran. J. Psychiatry Behav. Sci."},{"key":"10.1016\/j.toxrep.2025.102159_bib5","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.toxlet.2017.07.889","article-title":"Cognitive and emotional impairments after cutaneous intoxication by CEES (a sulfur mustard analog) in mice","volume":"293","author":"Gros-D\u00e9sormeaux","year":"2018","journal-title":"Toxicol. Lett."},{"issue":"3","key":"10.1016\/j.toxrep.2025.102159_bib6","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.cbi.2013.06.013","article-title":"Historical perspective on effects and treatment of sulfur mustard injuries","volume":"206","author":"Graham","year":"2013","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.toxrep.2025.102159_bib7","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.toxlet.2021.02.007","article-title":"Ocular toxicity of mustard gas: a concise review","volume":"343","author":"Fuchs","year":"2021","journal-title":"Toxicol. Lett."},{"issue":"6","key":"10.1016\/j.toxrep.2025.102159_bib8","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0039-6257(97)00021-0","article-title":"Ocular injury by mustard gas","volume":"41","author":"Solberg","year":"1997","journal-title":"Surv. Ophthalmol."},{"issue":"7","key":"10.1016\/j.toxrep.2025.102159_bib9","first-page":"577","article-title":"Ocular injuries following sulfur mustard exposure: clinical characteristics and treatment","volume":"4","author":"Vidan","year":"2002","journal-title":"Isr. Med. Assoc. J."},{"issue":"1","key":"10.1016\/j.toxrep.2025.102159_bib10","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/2008-2231-20-51","article-title":"A review on delayed toxic effects of sulfur mustard in Iranian veterans","volume":"20","author":"Mansour Razavi","year":"2012","journal-title":"Daru"},{"issue":"1","key":"10.1016\/j.toxrep.2025.102159_bib11","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1076\/ceyr.22.1.42.6975","article-title":"Characterization of acute and delayed ocular lesions induced by sulfur mustard in rabbits","volume":"22","author":"Kadar","year":"2001","journal-title":"Curr. Eye Res."},{"issue":"5","key":"10.1016\/j.toxrep.2025.102159_bib12","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1089\/jop.2010.0099","article-title":"Doxycycline hydrogels as a potential therapy for ocular vesicant injury","volume":"26","author":"Gordon","year":"2010","journal-title":"J. Ocul. Pharm. Ther."},{"issue":"4","key":"10.1016\/j.toxrep.2025.102159_bib13","doi-asserted-by":"crossref","first-page":"319","DOI":"10.3109\/15569527.2015.1127255","article-title":"Clinical progression of ocular injury following arsenical vesicant lewisite exposure","volume":"35","author":"Tewari-Singh","year":"2016","journal-title":"Cutan. Ocul. Toxicol."},{"key":"10.1016\/j.toxrep.2025.102159_bib14","series-title":"Pathologic Basis of Veterinary Disease (Sixth Edition)","first-page":"1265","article-title":"Chapter 21 - The Eye1","author":"Labelle","year":"2017"},{"issue":"7","key":"10.1016\/j.toxrep.2025.102159_bib15","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.jfo.2013.03.002","article-title":"N\u00e9ovascularisation corn\u00e9enne: aspects \u00e9pid\u00e9miologiques, physiopathologiques et cliniques","volume":"36","author":"Benayoun","year":"2013","journal-title":"J. fran\u00e7ais d\u2032ophtalmologie"},{"issue":"1","key":"10.1016\/j.toxrep.2025.102159_bib16","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1017\/S1049023X0000649X","article-title":"Mustard gas or sulfur mustard: an old chemical agent as a new terrorist threat","volume":"24","author":"Wattana","year":"2009","journal-title":"Prehosp. Disaster Med."},{"issue":"11","key":"10.1016\/j.toxrep.2025.102159_bib17","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/01.jom.0000094993.20914.d1","article-title":"Incidence of lung, eye, and skin lesions as late complications in 34,000 Iranians with wartime exposure to mustard agent","volume":"45","author":"Khateri","year":"2003","journal-title":"J. Occup. Environ. Med."},{"key":"10.1016\/j.toxrep.2025.102159_bib18","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.exer.2019.04.011","article-title":"A comprehensive analysis of corneal mRNA levels during sulfur mustard induced ocular late pathology in the rabbit model using RNA sequencing","volume":"184","author":"Horwitz","year":"2019","journal-title":"Exp. Eye Res."},{"issue":"1","key":"10.1016\/j.toxrep.2025.102159_bib19","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.tox.2008.10.026","article-title":"Ocular injuries following sulfur mustard exposure\u2014pathological mechanism and potential therapy","volume":"263","author":"Kadar","year":"2009","journal-title":"Toxicology"},{"issue":"10","key":"10.1016\/j.toxrep.2025.102159_bib20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0258503","article-title":"Pathophysiology and inflammatory biomarkers of sulfur mustard-induced corneal injury in rabbits","volume":"16","author":"Goswami","year":"2021","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.toxrep.2025.102159_bib21","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1080\/15569520701212399","article-title":"Cutaneous and ocular late complications of sulfur mustard in Iranian veterans","volume":"26","author":"Shohrati","year":"2007","journal-title":"Cutan. Ocul. Toxicol."},{"issue":"3","key":"10.1016\/j.toxrep.2025.102159_bib22","first-page":"458","article-title":"Ophthalmological aspects of mustard gas poisoning (focus on management)","volume":"13","author":"Rafati-Rahimzadeh","year":"2022","journal-title":"Casp. J. Intern. Med."},{"issue":"12","key":"10.1016\/j.toxrep.2025.102159_bib23","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1167\/tvst.9.12.6","article-title":"A novel topical ophthalmic formulation to mitigate acute mustard gas keratopathy in vivo: a pilot study","volume":"9","author":"Tripathi","year":"2020","journal-title":"Transl. Vis. Sci. Technol."},{"key":"10.1016\/j.toxrep.2025.102159_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2019.107698","article-title":"Validation of the Icare(\u00ae) TONOVET plus rebound tonometer in normal rabbit eyes","volume":"185","author":"Gloe","year":"2019","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.toxrep.2025.102159_bib25","first-page":"271","article-title":"Normal intraocular pressure in English Angora and Dutch and New Zealand white rabbits","volume":"20","author":"Rajaei","year":"2016","journal-title":"Online J. Vet. Res."},{"key":"10.1016\/j.toxrep.2025.102159_bib26","unstructured":"Eyedocs. IOP Correction for Central Corneal Thickness (CCT) [Available from: \u3008https:\/\/www.eyedocs.co.uk\/ophthalmology-articles\/glaucoma\/769-iop-and-corneal-thickness\u3009."},{"issue":"2","key":"10.1016\/j.toxrep.2025.102159_bib27","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3109\/09273948.2011.647228","article-title":"Hypotony in patients with uveitis: the multicenter uveitis steroid treatment (MUST) trial","volume":"20","author":"Sen","year":"2012","journal-title":"Ocul. Immunol. Inflamm."},{"issue":"11","key":"10.1016\/j.toxrep.2025.102159_bib28","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1016\/j.ophtha.2012.05.032","article-title":"Risk of hypotony in noninfectious uveitis","volume":"119","author":"Daniel","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.toxrep.2025.102159_bib29","unstructured":"E.G. Uveitis - Simple World Small Animal Veterinary Association World Congress Proceedings 2015 [Available from: \u3008https:\/\/www.vin.com\/apputil\/content\/defaultadv1.aspx?pId=14365&catId=73695&id=7259194\u3009."},{"issue":"3","key":"10.1016\/j.toxrep.2025.102159_bib30","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1097\/ICO.0B013E31823D02CD","article-title":"Pathogenesis of acute and delayed corneal lesions after ocular exposure to sulfur mustard vapor","volume":"31","author":"McNutt","year":"2012","journal-title":"Cornea"},{"issue":"3","key":"10.1016\/j.toxrep.2025.102159_bib31","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.exer.2003.06.003","article-title":"Corneal oedema in ocular hypotony","volume":"78","author":"Hatton","year":"2004","journal-title":"Exp. Eye Res."},{"issue":"23","key":"10.1016\/j.toxrep.2025.102159_bib32","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242316661","article-title":"Animal models in eye research: focus on corneal pathologies","volume":"24","author":"Loiseau","year":"2023","journal-title":"Int. J. Mol. Sci."}],"container-title":["Toxicology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214750025002781?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214750025002781?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T06:35:20Z","timestamp":1773297320000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214750025002781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":32,"alternative-id":["S2214750025002781"],"URL":"https:\/\/doi.org\/10.1016\/j.toxrep.2025.102159","relation":{},"ISSN":["2214-7500"],"issn-type":[{"value":"2214-7500","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predicting the severity of eye damage induced in rabbits after sulfur mustard vapor exposure","name":"articletitle","label":"Article Title"},{"value":"Toxicology Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.toxrep.2025.102159","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"102159"}}