{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T18:02:34Z","timestamp":1794074554094,"version":"4.8.0"},"reference-count":135,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmn.com","cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Plant Science"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.tplants.2020.01.001","type":"journal-article","created":{"date-parts":[[2020,2,10]],"date-time":"2020-02-10T16:41:16Z","timestamp":1581352876000},"page":"466-476","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":87,"title":["Parallel Transcriptional Regulation of Artemisinin and Flavonoid Biosynthesis"],"prefix":"10.1016","volume":"25","author":[{"given":"Danial","family":"Hassani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueqing","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Khalid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyn K.C.","family":"Rose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kexuan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tplants.2020.01.001_bb0005","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1093\/jxb\/erg199","article-title":"Significance of skin flavonoids for UV-B-protection in apple fruits","volume":"54","author":"Solovchenko","year":"2003","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.tplants.2020.01.001_bb0010","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s11434-015-0929-2","article-title":"Recent advances in biosynthesis of bioactive compounds in traditional Chinese medicinal plants","volume":"61","author":"Yang","year":"2016","journal-title":"Sci. Bull."},{"key":"10.1016\/j.tplants.2020.01.001_bb0015","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.phytochem.2009.10.015","article-title":"Artemisinin biosynthesis in growing plants of Artemisia annua. A 13CO2 study","volume":"71","author":"Schramek","year":"2010","journal-title":"Phytochemistry"},{"key":"10.1016\/j.tplants.2020.01.001_bb0020","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1211\/jpp.60.4.0010","article-title":"Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan-and antigen-induced inflammation","volume":"60","author":"Spiller","year":"2008","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0025","series-title":"Medical Herbalism: The Science and Practice of Herbal Medicine","author":"Hoffmann","year":"2003"},{"key":"10.1016\/j.tplants.2020.01.001_bb0030","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1055\/s-2006-947198","article-title":"Antiviral effect of artemisinin from Artemisia annua against a model member of the Flaviviridae family, the bovine viral diarrhoea virus (BVDV)","volume":"72","author":"Romero","year":"2006","journal-title":"Planta Med."},{"key":"10.1016\/j.tplants.2020.01.001_bb0035","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/hed.20524","article-title":"Effects of artemisinin and its derivatives on growth inhibition and apoptosis of oral cancer cells","volume":"29","author":"Nam","year":"2007","journal-title":"Head Neck"},{"key":"10.1016\/j.tplants.2020.01.001_bb0040","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1093\/pcp\/pcz084","article-title":"Light-induced artemisinin biosynthesis is regulated by the bZIP transcription factor AaHY5 in Artemisia annua","volume":"60","author":"Hao","year":"2019","journal-title":"Plant Cell Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0045","series-title":"World Malaria Report 2014","author":"World Health Organization","year":"2014"},{"key":"10.1016\/j.tplants.2020.01.001_bb0050","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1089\/acm.2008.0327","article-title":"Artemisia species: from traditional medicines to modern antimalarials \u2013 and back again","volume":"15","author":"Willcox","year":"2009","journal-title":"J. Altern. Complement. Med."},{"key":"10.1016\/j.tplants.2020.01.001_bb0055","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/S0024-3205(01)01447-3","article-title":"Simple and rapid physico-chemical methods to examine action of antimalarial drugs with hemin: its application to Artemisia annua constituents","volume":"70","author":"Bilia","year":"2002","journal-title":"Life Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0060","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/BF00236389","article-title":"Antimalarial activity of Artemisia annua flavonoids from whole plants and cell cultures","volume":"11","author":"Liu","year":"1992","journal-title":"Plant Cell Rep."},{"key":"10.1016\/j.tplants.2020.01.001_bb0065","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1046\/j.1365-2125.1999.00044.x","article-title":"Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin","volume":"48","author":"Svensson","year":"1999","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0070","unstructured":"Thornthwaite, J.T. Scientific Formulations LLC. Therapeutics for Malaria, WO2017053593"},{"key":"10.1016\/j.tplants.2020.01.001_bb0075","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.phymed.2017.04.006","article-title":"Artemisia annua dried leaf tablets treated malaria resistant to ACT and iv artesunate","volume":"32","author":"Daddy","year":"2017","journal-title":"Phytomedicine"},{"key":"10.1016\/j.tplants.2020.01.001_bb0080","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.tplants.2017.12.006","article-title":"Combinatorial transcriptional control of plant specialized metabolism","volume":"23","author":"Colinas","year":"2018","journal-title":"Trends Plant Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0085","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1146\/annurev-arplant-050312-120116","article-title":"Network analysis of the MVA and MEP pathways for isoprenoid synthesis","volume":"64","author":"Vranov\u00e1","year":"2013","journal-title":"Annu. Rev. Plant Biol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0090","doi-asserted-by":"crossref","first-page":"421","DOI":"10.6026\/97320630004421","article-title":"Isolation, characterization and structural studies of amorpha-4,11-diene synthase (ADS3963) from Artemisia annua L","volume":"4","author":"Alam","year":"2010","journal-title":"Bioinformation"},{"key":"10.1016\/j.tplants.2020.01.001_bb0095","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1038\/nature04640","article-title":"Production of the antimalarial drug precursor artemisinic acid in engineered yeast","volume":"440","author":"Ro","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.tplants.2020.01.001_bb0100","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1016\/j.febslet.2006.01.065","article-title":"Artemisia annua L. (Asteraceae) trichome-specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin","volume":"580","author":"Teoh","year":"2006","journal-title":"FEBS Lett."},{"key":"10.1016\/j.tplants.2020.01.001_bb0105","doi-asserted-by":"crossref","first-page":"21501","DOI":"10.1074\/jbc.M803090200","article-title":"The molecular cloning of artemisinic aldehyde \u039411(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua","volume":"283","author":"Zhang","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tplants.2020.01.001_bb0110","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/aob\/mch011","article-title":"New approaches for studying and exploiting an old protuberance, the plant trichome","volume":"93","author":"Wagner","year":"2004","journal-title":"Ann. Bot."},{"key":"10.1016\/j.tplants.2020.01.001_bb0115","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0003-9861(02)00348-X","article-title":"Molecular cloning and characterization of a new linalool synthase","volume":"405","author":"Crowell","year":"2002","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.tplants.2020.01.001_bb0120","first-page":"1214","article-title":"Biotechnology of flavonoids and other phenylpropanoid-derived natural products. Part I. Chemical diversity, impacts on plant biology and human health","volume":"2","author":"Ververidis","year":"2007","journal-title":"Biotechnol. J. Healthc. Nutr. Technol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0125","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.scienta.2008.03.016","article-title":"Analysis of petal anthocyanins to investigate coloration mechanism in herbaceous peony cultivars","volume":"117","author":"Jia","year":"2008","journal-title":"Sci. Hortic."},{"key":"10.1016\/j.tplants.2020.01.001_bb0130","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1432-1033.1979.tb13235.x","article-title":"Flavanone synthase from Petroselinum hortense: molecular weight, subunit composition, size of messenger RNA, and absence of pantetheinyl residue","volume":"99","author":"Kreuzaler","year":"1979","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.tplants.2020.01.001_bb0135","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1038\/79025","article-title":"Structure and mechanism of the evolutionarily unique plant enzyme chalcone isomerase","volume":"7","author":"Jez","year":"2000","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0140","doi-asserted-by":"crossref","first-page":"5168","DOI":"10.1021\/bi0255266","article-title":"Role of hydrogen bonds in the reaction mechanism of chalcone isomerase","volume":"41","author":"Jez","year":"2002","journal-title":"Biochemistry"},{"key":"10.1016\/j.tplants.2020.01.001_bb0145","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.2307\/3870058","article-title":"Genetics and biochemistry of anthocyanin biosynthesis","volume":"7","author":"Holton","year":"1995","journal-title":"Plant Cell"},{"key":"10.1016\/j.tplants.2020.01.001_bb0150","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1016\/j.phytochem.2005.07.013","article-title":"Flavones and flavone synthases","volume":"66","author":"Martens","year":"2005","journal-title":"Phytochemistry"},{"key":"10.1016\/j.tplants.2020.01.001_bb0155","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1094\/MPMI.1999.12.6.479","article-title":"cDNA cloning of a sorghum pathogenesis-related protein (PR-10) and differential expression of defense-related genes following inoculation with Cochliobolus heterostrophus or Colletotrichum sublineolum","volume":"12","author":"Lo","year":"1999","journal-title":"Mol. Plant-Microbe Interact."},{"key":"10.1016\/j.tplants.2020.01.001_bb0160","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1146\/annurev.arplant.57.032905.105248","article-title":"The genetics and biochemistry of floral pigments","volume":"57","author":"Grotewold","year":"2006","journal-title":"Annu. Rev. Plant Biol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0165","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.plantsci.2005.04.007","article-title":"cDNA cloning and characterization of UDP-glucose: anthocyanidin 3-O-glucosyltransferase in Iris hollandica","volume":"169","author":"Yoshihara","year":"2005","journal-title":"Plant Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0170","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1242\/jcs.104.4.949","article-title":"Signal transduction and nuclear targeting: regulation of transcription factor activity by subcellular localisation","volume":"104","author":"Whiteside","year":"1993","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0175","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.pbi.2016.07.004","article-title":"Transcriptional regulation by complex interplay between post-translational modifications","volume":"33","author":"Skelly","year":"2016","journal-title":"Curr. Opin. Plant Biol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0180","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1101\/gad.521809","article-title":"Metabolic intermediates selectively stimulate transcription factor interaction and modulate phosphate and purine pathways","volume":"23","author":"Pinson","year":"2009","journal-title":"Genes Dev."},{"key":"10.1016\/j.tplants.2020.01.001_bb0185","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1104\/pp.118.4.1111","article-title":"Transcriptional regulation in plants: the importance of combinatorial control","volume":"118","author":"Singh","year":"1998","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0190","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.tplants.2010.02.006","article-title":"WRKY transcription factors","volume":"15","author":"Rushton","year":"2010","journal-title":"Trends Plant Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0195","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1467-7652.2011.00634.x","article-title":"WRKY transcription factors: key components in abscisic acid signalling","volume":"10","author":"Rushton","year":"2012","journal-title":"Plant Biotechnol. J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0200","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s11103-009-9563-1","article-title":"The grapevine transcription factor WRKY2 influences the lignin pathway and xylem development in tobacco","volume":"72","author":"Guillaumie","year":"2010","journal-title":"Plant Mol. Biol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0205","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1073\/pnas.1121134109","article-title":"Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesis","volume":"109","author":"Grunewald","year":"2012","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0210","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1104\/pp.111.172502","article-title":"Auxin and ethylene induce flavonol accumulation through distinct transcriptional networks","volume":"156","author":"Lewis","year":"2011","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0215","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.3389\/fpls.2016.01979","article-title":"A grapevine TTG2-like WRKY transcription factor is involved in regulating vacuolar transport and flavonoid biosynthesis","volume":"7","author":"Amato","year":"2017","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0220","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1105\/tpc.107.052274","article-title":"Arabidopsis TRANSPARENT TESTA GLABRA2 is directly regulated by R2R3 MYB transcription factors and is involved in regulation of GLABRA2 transcription in epidermal differentiation","volume":"19","author":"Ishida","year":"2007","journal-title":"Plant Cell"},{"key":"10.1016\/j.tplants.2020.01.001_bb0225","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1093\/pcp\/pcp149","article-title":"Isolation and characterization of AaWRKY1, an Artemisia annua transcription factor that regulates the amorpha-4,11-diene synthase gene, a key gene of artemisinin biosynthesis","volume":"50","author":"Ma","year":"2009","journal-title":"Plant Cell Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0230","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s11434-015-0983-9","article-title":"Transcriptional regulation of artemisinin biosynthesis in Artemisia annua L","volume":"61","author":"Shen","year":"2016","journal-title":"Sci. Bull."},{"key":"10.1016\/j.tplants.2020.01.001_bb0235","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/s11105-012-0531-6","article-title":"Genome-wide analysis of the AP2\/ERF gene family in Prunus mume","volume":"31","author":"Du","year":"2013","journal-title":"Plant Mol. Biol. Report."},{"key":"10.1016\/j.tplants.2020.01.001_bb0240","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1104\/pp.105.073783","article-title":"Genome-wide analysis of the ERF gene family in Arabidopsis and rice","volume":"140","author":"Nakano","year":"2006","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0245","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1186\/1471-2164-11-719","article-title":"Genomic and transcriptomic analysis of the AP2\/ERF superfamily in Vitis vinifera","volume":"11","author":"Licausi","year":"2010","journal-title":"BMC Genomics"},{"key":"10.1016\/j.tplants.2020.01.001_bb0250","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1104\/pp.106.086637","article-title":"AtERF14, a member of the ERF family of transcription factors, plays a nonredundant role in plant defense","volume":"143","author":"O\u00f1ate-S\u00e1nchez","year":"2007","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0255","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1104\/pp.108.126813","article-title":"Transcriptional modulation of ethylene response factor protein JERF3 in the oxidative stress response enhances tolerance of tobacco seedlings to salt, drought, and freezing","volume":"148","author":"Wu","year":"2008","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0260","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0958-1669(02)00308-7","article-title":"Engineering secondary metabolite production in plants","volume":"13","author":"Verpoorte","year":"2002","journal-title":"Curr. Opin. Biotechnol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0265","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1126\/science.289.5477.295","article-title":"ORCA3, a jasmonate-responsive transcriptional regulator of plant primary and secondary metabolism","volume":"289","author":"van der Fits","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.tplants.2020.01.001_bb0270","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1104\/pp.108.117523","article-title":"The AP2\/ERF domain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense","volume":"147","author":"Pr\u00e9","year":"2008","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0275","doi-asserted-by":"crossref","first-page":"4421","DOI":"10.1093\/jxb\/ert257","article-title":"Ethylene is involved in strawberry fruit ripening in an organ-specific manner","volume":"64","author":"Merchante","year":"2013","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.tplants.2020.01.001_bb0280","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1007\/s11105-015-0963-x","article-title":"Molecular characterization of ethylene-regulated anthocyanin biosynthesis in plums during fruit ripening","volume":"34","author":"Cheng","year":"2016","journal-title":"Plant Mol. Biol. Report."},{"key":"10.1016\/j.tplants.2020.01.001_bb0285","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1105\/tpc.110.081273","article-title":"Transcriptome and metabolite profiling show that APETALA2a is a major regulator of tomato fruit ripening","volume":"23","author":"Karlova","year":"2011","journal-title":"Plant Cell"},{"key":"10.1016\/j.tplants.2020.01.001_bb0290","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1111\/tpj.13289","article-title":"Apple (Malus domestica) Md ERF 2 negatively affects ethylene biosynthesis during fruit ripening by suppressing Md ACS 1 transcription","volume":"88","author":"Li","year":"2016","journal-title":"Plant J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0295","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1093\/jxb\/eri246","article-title":"Methyl jasmonate stimulates the de novo biosynthesis of vitamin C in plant cell suspensions","volume":"56","author":"Wolucka","year":"2005","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.tplants.2020.01.001_bb0300","doi-asserted-by":"crossref","first-page":"4670","DOI":"10.1111\/j.1742-4658.2007.05997.x","article-title":"Malaria \u2212 an overview","volume":"274","author":"Tuteja","year":"2007","journal-title":"FEBS J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0305","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1093\/mp\/ssr087","article-title":"The jasmonate-responsive AP2\/ERF transcription factors AaERF1 and AaERF2 positively regulate artemisinin biosynthesis in Artemisia annua L","volume":"5","author":"Yu","year":"2012","journal-title":"Mol. Plant"},{"key":"10.1016\/j.tplants.2020.01.001_bb0310","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1111\/nph.12207","article-title":"AaORA, a trichome-specific AP2\/ERF transcription factor of Artemisia annua, is a positive regulator in the artemisinin biosynthetic pathway and in disease resistance to Botrytis cinerea","volume":"198","author":"Lu","year":"2013","journal-title":"New Phytol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0315","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0959-440X(94)90054-X","article-title":"Getting a grip on DNA recognition: structures of the basic region leucine zipper, and the basic region helix-loop-helix DNA-binding domains","volume":"4","author":"Ellenberger","year":"1994","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0320","first-page":"123","article-title":"Transcription factors. 1: bZIP proteins","volume":"1","author":"Hurst","year":"1994","journal-title":"Protein Profile"},{"key":"10.1016\/j.tplants.2020.01.001_bb0325","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1105\/tpc.010362","article-title":"Arabidopsis basic leucine zipper proteins that mediate stress-responsive abscisic acid signaling","volume":"14","author":"Kang","year":"2002","journal-title":"Plant Cell"},{"key":"10.1016\/j.tplants.2020.01.001_bb0330","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1104\/pp.108.128199","article-title":"Characterization of OsbZIP23 as a key player of the basic leucine zipper transcription factor family for conferring abscisic acid sensitivity and salinity and drought tolerance in rice","volume":"148","author":"Xiang","year":"2008","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0335","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1093\/molbev\/msr121","article-title":"MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods","volume":"28","author":"Tamura","year":"2011","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0340","doi-asserted-by":"crossref","first-page":"16398","DOI":"10.1073\/pnas.0808463105","article-title":"A membrane-tethered transcription factor defines a branch of the heat stress response in Arabidopsis thaliana","volume":"105","author":"Gao","year":"2008","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0345","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1101\/gad.12.2.208","article-title":"The maize geneliguleless2 encodes a basic leucine zipper protein involved in the establishment of the leaf blade\u2013sheath boundary","volume":"12","author":"Walsh","year":"1998","journal-title":"Genes Dev."},{"key":"10.1016\/j.tplants.2020.01.001_bb0350","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.bbrc.2007.08.026","article-title":"A conserved proline residue in the leucine zipper region of AtbZIP34 and AtbZIP61 in Arabidopsis thaliana interferes with the formation of homodimer","volume":"362","author":"Shen","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.tplants.2020.01.001_bb0355","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/S1360-1385(01)02223-3","article-title":"bZIP transcription factors in Arabidopsis","volume":"7","author":"Jakoby","year":"2002","journal-title":"Trends Plant Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0360","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s00239-002-2386-1","article-title":"Evolutionary pattern of angiosperm bZIP factors homologous to the maize Opaque2 regulatory protein","volume":"56","author":"Vincentz","year":"2003","journal-title":"J. Mol. Evol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0365","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1074\/jbc.275.3.1723","article-title":"ABFs, a family of ABA-responsive element binding factors","volume":"275","author":"Choi","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tplants.2020.01.001_bb0370","doi-asserted-by":"crossref","first-page":"11632","DOI":"10.1073\/pnas.190309197","article-title":"Arabidopsis basic leucine zipper transcription factors involved in an abscisic acid-dependent signal transduction pathway under drought and high-salinity conditions","volume":"97","author":"Uno","year":"2000","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0375","doi-asserted-by":"crossref","first-page":"9175","DOI":"10.1074\/jbc.274.14.9175","article-title":"Barley BLZ2, a seed-specific bZIP protein that interacts with BLZ1 in vivo and activates transcription from the GCN4-like motif of B-hordein promoters in barley endosperm","volume":"274","author":"O\u00f1ate","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tplants.2020.01.001_bb0380","doi-asserted-by":"crossref","first-page":"7685","DOI":"10.1073\/pnas.94.14.7685","article-title":"A maize zinc-finger protein binds the prolamin box in zein gene promoters and interacts with the basic leucine zipper transcriptional activator Opaque2","volume":"94","author":"Vicente-Carbajosa","year":"1997","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0385","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1093\/emboj\/16.4.726","article-title":"Rapid stimulation of a soybean protein-serine kinase that phosphorylates a novel bZIP DNA-binding protein, G\/HBF-1, during the induction of early transcription-dependent defenses","volume":"16","author":"Dr\u00f6ge-Laser","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0390","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1002\/j.1460-2075.1991.tb07702.x","article-title":"Light-inducible and constitutively expressed DNA-binding proteins recognizing a plant promoter element with functional relevance in light responsiveness","volume":"10","author":"Weisshaar","year":"1991","journal-title":"EMBO J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0395","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1046\/j.1365-313X.1999.00541.x","article-title":"The liguleless2 gene of maize functions during the transition from the vegetative to the reproductive shoot apex","volume":"19","author":"Walsh","year":"1999","journal-title":"Plant J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0400","doi-asserted-by":"crossref","first-page":"4997","DOI":"10.1093\/emboj\/19.18.4997","article-title":"HY5 stability and activity in Arabidopsis is regulated by phosphorylation in its COP1 binding domain","volume":"19","author":"Hardtke","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0405","doi-asserted-by":"crossref","first-page":"13274","DOI":"10.4238\/2015.October.26.24","article-title":"Genomic identification of group A bZIP transcription factors and their responses to abiotic stress in carrot","volume":"14","author":"Que","year":"2015","journal-title":"Genet. Mol. Res."},{"key":"10.1016\/j.tplants.2020.01.001_bb0410","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s11103-004-6910-0","article-title":"Differential combinatorial interactions of cis-acting elements recognized by R2R3-MYB, BZIP, and BHLH factors control light-responsive and tissue-specific activation of phenylpropanoid biosynthesis genes","volume":"57","author":"Hartmann","year":"2005","journal-title":"Plant Mol. Biol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0415","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1104\/pp.109.142059","article-title":"The grapevine R2R3-MYB transcription factor VvMYBF1 regulates flavonol synthesis in developing grape berries","volume":"151","author":"Czemmel","year":"2009","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0420","first-page":"88","article-title":"The Arabidopsis bZIP transcription factor HY5 regulates expression of the PFG1\/MYB12 gene in response to light and ultraviolet-B radiation","volume":"33","author":"Stracke","year":"2010","journal-title":"Plant Cell Environ."},{"key":"10.1016\/j.tplants.2020.01.001_bb0425","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.tplants.2008.03.002","article-title":"Post-translational regulation of plant bZIP factors","volume":"13","author":"Sch\u00fctze","year":"2008","journal-title":"Trends Plant Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0430","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1105\/tpc.106.047688","article-title":"Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development","volume":"19","author":"Lee","year":"2007","journal-title":"Plant Cell"},{"key":"10.1016\/j.tplants.2020.01.001_bb0435","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.molp.2014.12.004","article-title":"A basic leucine zipper transcription factor, AabZIP1, connects abscisic acid signaling with artemisinin biosynthesis in Artemisia annua","volume":"8","author":"Zhang","year":"2015","journal-title":"Mol. Plant"},{"key":"10.1016\/j.tplants.2020.01.001_bb0440","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1093\/molbev\/msg088","article-title":"The basic helix\u2013loop\u2013helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity","volume":"20","author":"Heim","year":"2003","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0445","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1210\/mend.13.5.0271","article-title":"Basic helix-loop-helix proteins can act at the E-box within the serum response element of the c-fos promoter to influence hormone-induced promoter activation in Sertoli cells","volume":"13","author":"Chaudhary","year":"1999","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0450","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/sj.embor.7400096","article-title":"Convergent evolution of gene networks by single-gene duplications in higher eukaryotes","volume":"5","author":"Amoutzias","year":"2004","journal-title":"EMBO Rep."},{"key":"10.1016\/j.tplants.2020.01.001_bb0455","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.tplants.2014.12.001","article-title":"Transcriptional control of flavonoid biosynthesis by MYB\u2013bHLH\u2013WDR complexes","volume":"20","author":"Xu","year":"2015","journal-title":"Trends Plant Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0460","article-title":"Genome-wide characterisation and analysis of bHLH transcription factors related to tanshinone biosynthesis in Salvia miltiorrhiza","volume":"5","author":"Zhang","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.tplants.2020.01.001_bb0465","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/tpj.13230","article-title":"The basic helix-loop-helix transcription factor BIS 2 is essential for monoterpenoid indole alkaloid production in the medicinal plant Catharanthus roseus","volume":"88","author":"Van Moerkercke","year":"2016","journal-title":"Plant J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0470","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1104\/pp.15.01645","article-title":"The bHLH transcription factors TSAR1 and TSAR2 regulate triterpene saponin biosynthesis in Medicago truncatula","volume":"170","author":"Mertens","year":"2016","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0475","doi-asserted-by":"crossref","first-page":"519","DOI":"10.3389\/fpls.2014.00519","article-title":"Control of anthocyanin and non-flavonoid compounds by anthocyanin-regulating MYB and bHLH transcription factors in Nicotiana benthamiana leaves","volume":"5","author":"Outchkourov","year":"2014","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0480","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0143892","article-title":"A novel bHLH transcription factor involved in regulating anthocyanin biosynthesis in chrysanthemums (Chrysanthemum morifolium Ramat.)","volume":"10","author":"Xiang","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.tplants.2020.01.001_bb0485","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S1360-1385(98)01242-4","article-title":"How genes paint flowers and seeds","volume":"3","author":"Mol","year":"1998","journal-title":"Trends Plant Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0490","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.tplants.2007.11.012","article-title":"MYB transcription factors that colour our fruit","volume":"13","author":"Allan","year":"2008","journal-title":"Trends Plant Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0495","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1111\/nph.13874","article-title":"The jasmonate-responsive AaMYC2 transcription factor positively regulates artemisinin biosynthesis in Artemisia annua","volume":"210","author":"Shen","year":"2016","journal-title":"New Phytol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0500","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1093\/pcp\/pcu090","article-title":"Cloning and characterization of AabHLH1, a bHLH transcription factor that positively regulates artemisinin biosynthesis in Artemisia annua","volume":"55","author":"Ji","year":"2014","journal-title":"Plant Cell Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0505","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/nsb0296-178","article-title":"The cavity in the hydrophobic core of Myb DNA-binding domain is reserved for DNA recognition and trans-activation","volume":"3","author":"Ogata","year":"1996","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0510","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1104\/pp.103.027201","article-title":"Evolutionary dynamics of the DNA-binding domains in putative R2R3-MYB genes identified from rice subspecies indica and japonica genomes","volume":"134","author":"Jia","year":"2004","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0515","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s10265-005-0192-8","article-title":"Conservation and diversification of three-repeat Myb transcription factors in plants","volume":"118","author":"Ito","year":"2005","journal-title":"J. Plant Res."},{"key":"10.1016\/j.tplants.2020.01.001_bb0520","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1242\/dev.02801","article-title":"R1R2R3-Myb proteins positively regulate cytokinesis through activation of KNOLLE transcription in Arabidopsis thaliana","volume":"134","author":"Haga","year":"2007","journal-title":"Development"},{"key":"10.1016\/j.tplants.2020.01.001_bb0525","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.pbi.2009.07.015","article-title":"One, two, three\u2026 models for trichome patterning in Arabidopsis?","volume":"12","author":"Pesch","year":"2009","journal-title":"Curr. Opin. Plant Biol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0530","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1111\/j.1365-313X.2008.03565.x","article-title":"AtMYBL2, a protein with a single MYB domain, acts as a negative regulator of anthocyanin biosynthesis in Arabidopsis","volume":"55","author":"Matsui","year":"2008","journal-title":"Plant J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0535","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1104\/pp.108.133272","article-title":"CIRCADIAN CLOCK ASSOCIATED1 and LATE ELONGATED HYPOCOTYL function synergistically in the circadian clock of Arabidopsis","volume":"150","author":"Lu","year":"2009","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0540","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1105\/tpc.108.065250","article-title":"GLK transcription factors coordinate expression of the photosynthetic apparatus in Arabidopsis","volume":"21","author":"Waters","year":"2009","journal-title":"Plant Cell"},{"key":"10.1016\/j.tplants.2020.01.001_bb0545","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1111\/j.1365-313X.2007.03078.x","article-title":"Differential regulation of closely related R2R3-MYB transcription factors controls flavonol accumulation in different parts of the Arabidopsis thaliana seedling","volume":"50","author":"Stracke","year":"2007","journal-title":"Plant J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0550","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1146\/annurev.arplant.57.032905.105252","article-title":"Genetics and biochemistry of seed flavonoids","volume":"57","author":"Lepiniec","year":"2006","journal-title":"Annu. Rev. Plant Biol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0555","doi-asserted-by":"crossref","first-page":"6150","DOI":"10.1093\/emboj\/19.22.6150","article-title":"Transcriptional repression by AtMYB4 controls production of UV-protecting sunscreens in Arabidopsis","volume":"19","author":"Jin","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0560","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1111\/j.1365-313X.2004.02280.x","article-title":"AtMYB32 is required for normal pollen development in Arabidopsis thaliana","volume":"40","author":"Preston","year":"2004","journal-title":"Plant J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0565","doi-asserted-by":"crossref","first-page":"13579","DOI":"10.1073\/pnas.250379897","article-title":"Identification of the residues in the Myb domain of maize C1 that specify the interaction with the bHLH cofactor R","volume":"97","author":"Grotewold","year":"2000","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0570","doi-asserted-by":"crossref","first-page":"2621","DOI":"10.1104\/pp.104.046367","article-title":"GENEVESTIGATOR. Arabidopsis microarray database and analysis toolbox","volume":"136","author":"Zimmermann","year":"2004","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0575","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S1369-5266(00)00199-0","article-title":"The R2R3-MYB gene family in Arabidopsis thaliana","volume":"4","author":"Stracke","year":"2001","journal-title":"Curr. Opin. Plant Biol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0580","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1111\/j.1365-313X.2008.03564.x","article-title":"MYBL2 is a new regulator of flavonoid biosynthesis in Arabidopsis thaliana","volume":"55","author":"Dubos","year":"2008","journal-title":"Plant J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0585","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1007\/s00299-008-0521-1","article-title":"Arabidopsis R2R3-MYB transcription factor AtMYB60 functions as a transcriptional repressor of anthocyanin biosynthesis in lettuce (Lactuca sativa)","volume":"27","author":"Park","year":"2008","journal-title":"Plant Cell Rep."},{"key":"10.1016\/j.tplants.2020.01.001_bb0590","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.plaphy.2009.02.015","article-title":"Overexpression of a grapevine R2R3-MYB factor in tomato affects vegetative development, flower morphology and flavonoid and terpenoid metabolism","volume":"47","author":"Mahjoub","year":"2009","journal-title":"Plant Physiol. Biochem."},{"key":"10.1016\/j.tplants.2020.01.001_bb0595","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1111\/tpj.13509","article-title":"AaMYB 1 and its orthologue AtMYB 61 affect terpene metabolism and trichome development in Artemisia annua and Arabidopsis thaliana","volume":"90","author":"Mat\u00edas-Hern\u00e1ndez","year":"2017","journal-title":"Plant J."},{"key":"10.1016\/j.tplants.2020.01.001_bb0600","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/nph.14789","article-title":"The roles of AaMIXTA1 in regulating the initiation of glandular trichomes and cuticle biosynthesis in Artemisia annua","volume":"217","author":"Shi","year":"2018","journal-title":"New Phytol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0605","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1105\/tpc.111.083261","article-title":"The Jasmonate-ZIM-domain proteins interact with the WD-repeat\/bHLH\/MYB complexes to regulate jasmonate-mediated anthocyanin accumulation and trichome initiation in Arabidopsis thaliana","volume":"23","author":"Qi","year":"2011","journal-title":"Plant Cell"},{"key":"10.1016\/j.tplants.2020.01.001_bb0610","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1105\/tpc.107.055178","article-title":"EST analysis of hop glandular trichomes identifies an O-methyltransferase that catalyzes the biosynthesis of xanthohumol","volume":"20","author":"Nagel","year":"2008","journal-title":"Plant Cell"},{"key":"10.1016\/j.tplants.2020.01.001_bb0615","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1104\/pp.108.125187","article-title":"Terpene biosynthesis in glandular trichomes of hop","volume":"148","author":"Wang","year":"2008","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0620","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1104\/pp.112.195271","article-title":"Characterization of an isoflavonoid-specific prenyltransferase from Lupinus albus","volume":"159","author":"Shen","year":"2012","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0625","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1104\/pp.112.194233","article-title":"Assessing the biosynthetic capabilities of secretory glands in Citrus peel","volume":"159","author":"Voo","year":"2012","journal-title":"Plant Physiol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0630","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1469-8137.2012.04161.x","article-title":"PAP1 transcription factor enhances production of phenylpropanoid and terpenoid scent compounds in rose flowers","volume":"195","author":"Zvi","year":"2012","journal-title":"New Phytol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0635","doi-asserted-by":"crossref","first-page":"3847","DOI":"10.1093\/jxb\/erq196","article-title":"Subgroup 4 R2R3-MYBs in conifer trees: gene family expansion and contribution to the isoprenoid-and flavonoid-oriented responses","volume":"61","author":"Bedon","year":"2010","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.tplants.2020.01.001_bb0640","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1105\/tpc.022319","article-title":"JASMONATE-INSENSITIVE1 encodes a MYC transcription factor essential to discriminate between different jasmonate-regulated defense responses in Arabidopsis","volume":"16","author":"Lorenzo","year":"2004","journal-title":"Plant Cell"},{"key":"10.1016\/j.tplants.2020.01.001_bb0645","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1105\/tpc.106.048017","article-title":"MYC2 differentially modulates diverse jasmonate-dependent functions in Arabidopsis","volume":"19","author":"Dombrecht","year":"2007","journal-title":"Plant Cell"},{"key":"10.1016\/j.tplants.2020.01.001_bb0650","doi-asserted-by":"crossref","first-page":"5085","DOI":"10.1093\/jxb\/ert298","article-title":"WRKY76 is a rice transcriptional repressor playing opposite roles in blast disease resistance and cold stress tolerance","volume":"64","author":"Yokotani","year":"2013","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.tplants.2020.01.001_bb0655","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1002\/bab.1403","article-title":"Molecular cloning and promoter analysis of the specific salicylic acid biosynthetic pathway gene phenylalanine ammonia-lyase (AaPAL1) from Artemisia annua","volume":"63","author":"Zhang","year":"2016","journal-title":"Biotechnol. Appl. Biochem."},{"key":"10.1016\/j.tplants.2020.01.001_bb0660","first-page":"55","article-title":"Overexpression of flavanone 3-hydroxylase gene (AaF3H) increases artemisinin content in Artemisia annua L","volume":"8","author":"Tingting","year":"2017","journal-title":"Prog. Biotechnol."},{"key":"10.1016\/j.tplants.2020.01.001_bb0665","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1073\/pnas.1413127112","article-title":"Dried whole-plant Artemisia annua slows evolution of malaria drug resistance and overcomes resistance to artemisinin","volume":"112","author":"Elfawal","year":"2015","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.tplants.2020.01.001_bb0670","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s11101-010-9166-0","article-title":"Artemisinin production in Artemisia annua: studies in planta and results of a novel delivery method for treating malaria and other neglected diseases","volume":"10","author":"Weathers","year":"2011","journal-title":"Phytochem. Rev."},{"key":"10.1016\/j.tplants.2020.01.001_bb0675","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.molp.2018.03.015","article-title":"The genome of Artemisia annua provides insight into the evolution of Asteraceae family and artemisinin biosynthesis","volume":"11","author":"Shen","year":"2018","journal-title":"Mol. Plant"}],"container-title":["Trends in Plant Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1360138520300157?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1360138520300157?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T18:11:36Z","timestamp":1761243096000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1360138520300157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":135,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["S1360138520300157"],"URL":"https:\/\/doi.org\/10.1016\/j.tplants.2020.01.001","relation":{},"ISSN":["1360-1385"],"issn-type":[{"value":"1360-1385","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Parallel Transcriptional Regulation of Artemisinin and Flavonoid Biosynthesis","name":"articletitle","label":"Article Title"},{"value":"Trends in Plant Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tplants.2020.01.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}