{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T18:48:47Z","timestamp":1784659727664,"version":"3.55.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Hotung Charitable Foundation"},{"DOI":"10.13039\/501100003741","name":"ICREA","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003741","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Spanish Ministry of Economy, Industry and Competitiveness"},{"name":"Spanish Ministry of Science, Innovation and Universities","award":["RTI2018-097613-B-I00"],"award-info":[{"award-number":["RTI2018-097613-B-I00"]}]},{"name":"Spanish Ministry of Science, Innovation and Universities","award":["PGC2018-097655-B-I00"],"award-info":[{"award-number":["PGC2018-097655-B-I00"]}]}],"content-domain":{"domain":["bmn.com","cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Plant Science"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.tplants.2020.04.009","type":"journal-article","created":{"date-parts":[[2020,4,24]],"date-time":"2020-04-24T10:38:27Z","timestamp":1587724707000},"page":"635-643","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":158,"title":["Potential Applications of Plant Biotechnology against SARS-CoV-2"],"prefix":"10.1016","volume":"25","author":[{"given":"Teresa","family":"Capell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard M.","family":"Twyman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Armario-Najera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian K.-C.","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Schillberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Christou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tplants.2020.04.009_bb0005","doi-asserted-by":"crossref","first-page":"720","DOI":"10.3389\/fpls.2019.00720","article-title":"Critical analysis of the commercial potential of plants for the production of recombinant proteins","volume":"10","author":"Schillberg","year":"2019","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.tplants.2020.04.009_bb0010","doi-asserted-by":"crossref","first-page":"107519","DOI":"10.1016\/j.biotechadv.2020.107519","article-title":"Molecular farming \u2013 the slope of enlightenment","volume":"40","author":"Fischer","year":"2020","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.tplants.2020.04.009_bb0015","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/nm0598-601","article-title":"Characterization of a recombinant plant monoclonal secretory antibody and preventive immunotherapy in humans","volume":"4","author":"Ma","year":"1998","journal-title":"Nat. Med."},{"key":"10.1016\/j.tplants.2020.04.009_bb0020","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1007\/s10529-015-1908-z","article-title":"Molecular pharming\u2019s foot in the FDA\u2019s door: Protalix\u2019s trailblazing story","volume":"37","author":"Mor","year":"2015","journal-title":"Biotechnol. Lett."},{"key":"10.1016\/j.tplants.2020.04.009_bb0025","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1038\/nrg1177","article-title":"The production of recombinant pharmaceutical proteins in plants","volume":"4","author":"Ma","year":"2003","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.tplants.2020.04.009_bb0030","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1146\/annurev-arplant-050213-035850","article-title":"Plant molecular pharming for the treatment of chronic and infectious diseases","volume":"65","author":"Stoger","year":"2014","journal-title":"Annu. Rev. Plant Biol."},{"key":"10.1016\/j.tplants.2020.04.009_bb0035","article-title":"Glyco-engineering of plant-based expression systems","author":"Fischer","year":"2018","journal-title":"Adv. Biochem. Engin.\/Biotechnol."},{"key":"10.1016\/j.tplants.2020.04.009_bb0040","doi-asserted-by":"crossref","first-page":"5543","DOI":"10.2174\/1381612811319310009","article-title":"Seeds as a production system for molecular pharming applications: status and prospects","volume":"19","author":"Sabalza","year":"2013","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.tplants.2020.04.009_bb0045","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.biotechadv.2014.02.004","article-title":"Can plant biotechnology help to break the HIV\u2013malaria link?","volume":"32","author":"Vamvaka","year":"2014","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.tplants.2020.04.009_bb0050","doi-asserted-by":"crossref","first-page":"349","DOI":"10.4161\/hv.7.3.14266","article-title":"Emerging antibody products and Nicotiana manufacturing","volume":"7","author":"Whaley","year":"2011","journal-title":"Hum. Vaccines"},{"key":"10.1016\/j.tplants.2020.04.009_bb0055","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.jviromet.2007.07.002","article-title":"Development of a novel recombinant encapsidated RNA particle: evaluation as an internal control for diagnostic RT-PCR","volume":"146","author":"King","year":"2007","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.tplants.2020.04.009_bb0060","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1080\/15321819.2018.1515775","article-title":"A brief review of monoclonal antibody technology and its representative applications in immunoassays","volume":"39","author":"Gao","year":"2018","journal-title":"J. Immunoassay Immunochem."},{"key":"10.1016\/j.tplants.2020.04.009_bb0065","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/978-1-4939-7231-9_19","article-title":"Protein arrays I: antibody arrays","volume":"1654","author":"Yuan","year":"2017","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.tplants.2020.04.009_bb0070","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/342076a0","article-title":"Production of antibodies in transgenic plants","volume":"342","author":"Hiatt","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.tplants.2020.04.009_bb0075","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.3201\/eid1107.050219","article-title":"SARS vaccine development","volume":"11","author":"Jiang","year":"2005","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.tplants.2020.04.009_bb0080","doi-asserted-by":"crossref","first-page":"3870","DOI":"10.1128\/JVI.03566-14","article-title":"Severe acute respiratory syndrome coronaviruses with mutations in the E protein are attenuated and promising vaccine candidates","volume":"89","author":"Regla-Nava","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.tplants.2020.04.009_bb0085","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/s41541-020-0170-0","article-title":"The outbreak of SARS-CoV-2 pneumonia calls for viral vaccines","volume":"5","author":"Shang","year":"2020","journal-title":"NPJ Vaccines"},{"key":"10.1016\/j.tplants.2020.04.009_bb0090","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3390\/v12020135","article-title":"Return of the coronavirus: 2019-nCoV","volume":"12","author":"Gralinski","year":"2020","journal-title":"Viruses"},{"key":"10.1016\/j.tplants.2020.04.009_bb0095","article-title":"Receptor recognition by novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS","volume":"9","author":"Wan","year":"2020","journal-title":"J. Virol."},{"key":"10.1016\/j.tplants.2020.04.009_bb0100","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/nrmicro2090","article-title":"The spike protein of SARS-CoV\u2014a target for vaccine and therapeutic development","volume":"7","author":"Du","year":"2009","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.tplants.2020.04.009_bb0105","doi-asserted-by":"crossref","first-page":"178","DOI":"10.4161\/hv.6.2.9899","article-title":"Egg-independent vaccine strategies for highly pathogenic H5N1 influenza viruses","volume":"6","author":"Pandey","year":"2010","journal-title":"Hum. Vaccines"},{"key":"10.1016\/j.tplants.2020.04.009_bb0110","doi-asserted-by":"crossref","first-page":"11128","DOI":"10.1073\/pnas.96.20.11128","article-title":"Transient expression of a tumor-specific single-chain fragment and a chimeric antibody in tobacco leaves","volume":"96","author":"Vaquero","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tplants.2020.04.009_bb0115","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4161\/hv.7.0.14561","article-title":"Plant-based rapid production of recombinant subunit hemagglutinin vaccines targeting H1N1 and H5N1 influenza","volume":"7","author":"Shoji","year":"2011","journal-title":"Hum. Vaccines"},{"key":"10.1016\/j.tplants.2020.04.009_bb0120","unstructured":"British American Tobacco (2020) BAT Working on Potential COVID-19 Vaccine through US Bio-tech Subsidiary, BAT"},{"key":"10.1016\/j.tplants.2020.04.009_bb0125","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1080\/22221751.2020.1739565","article-title":"Emerging WuHan (COVID-19) coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26","volume":"9","author":"Vankadari","year":"2020","journal-title":"Emer. Microb. Infect."},{"key":"10.1016\/j.tplants.2020.04.009_bb0130","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.cell.2020.02.058","article-title":"Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein","volume":"181","author":"Walls","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.tplants.2020.04.009_bb0135","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1074\/mcp.M300048-MCP200","article-title":"Mass spectrometric characterization of proteins from the SARS virus: a preliminary report","volume":"2","author":"Krokhin","year":"2003","journal-title":"Mol. Cell. Proteom."},{"key":"10.1016\/j.tplants.2020.04.009_bb0140","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1006\/viro.1998.9315","article-title":"Expression of immunogenic glycoprotein S polypeptides from transmissible gastroenteritis coronavirus in transgenic plants","volume":"249","author":"G\u00f3mez","year":"1998","journal-title":"Virology"},{"key":"10.1016\/j.tplants.2020.04.009_bb0145","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/bit.25159","article-title":"Bioengineering virus-like particles as vaccines: virus-like particles as vaccines","volume":"111","author":"Lua","year":"2014","journal-title":"Biotechnol. Bioeng."},{"key":"10.1016\/j.tplants.2020.04.009_bb0150","doi-asserted-by":"crossref","DOI":"10.1002\/wnan.1587","article-title":"Plant molecular farming of virus-like nanoparticles as vaccines and reagents","volume":"12","author":"Rybicki","year":"2020","journal-title":"WIRES Nanomed. Nanobiotechnol."},{"key":"10.1016\/j.tplants.2020.04.009_bb0155","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1111\/j.1467-7652.2009.00496.x","article-title":"The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza","volume":"8","author":"D'Aoust","year":"2010","journal-title":"Plant Biotechnol. J."},{"key":"10.1016\/j.tplants.2020.04.009_bb0160","series-title":"Medicago Develops a Plant-Based Vaccine for Coronavirus","author":"Phillip Morris International","year":"2020"},{"key":"10.1016\/j.tplants.2020.04.009_bb0165","series-title":"iBio Announces Development of Proprietary COVID-19 Vaccine Candidates","author":"iBio","year":"2020"},{"key":"10.1016\/j.tplants.2020.04.009_bb0170","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2004168117","article-title":"Effectiveness of convalescent plasma therapy in severe COVID-19 patients","author":"Duan","year":"2020","journal-title":"Proc. Natl Acad. Sci. U. S. A."},{"key":"10.1016\/j.tplants.2020.04.009_bb0175","doi-asserted-by":"crossref","DOI":"10.1001\/jama.2020.4783","article-title":"Treatment of 5 critically ill patients with COVID-19 with convalescent plasma","author":"Shen","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.tplants.2020.04.009_bb0180","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3233\/HAB-150284","article-title":"The emergence of antibody therapies for Ebola","volume":"23","author":"Hiatt","year":"2015","journal-title":"Hum. Antibod."},{"key":"10.1016\/j.tplants.2020.04.009_bb0185","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/nature13777","article-title":"Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp","volume":"514","author":"Qiu","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.tplants.2020.04.009_bb0190","doi-asserted-by":"crossref","first-page":"17","DOI":"10.7774\/cevr.2015.4.1.17","article-title":"Ebola outbreak in Western Africa 2014: what is going on with Ebola virus?","volume":"4","author":"Na","year":"2015","journal-title":"Clin. Exp. Vaccine Res."},{"key":"10.1016\/j.tplants.2020.04.009_bb0195","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1111\/pbi.12416","article-title":"Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants","volume":"13","author":"Ma","year":"2015","journal-title":"Plant Biotechnol. J."},{"key":"10.1016\/j.tplants.2020.04.009_bb0200","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/j.1467-7652.2007.00306.x","article-title":"Recombinant antibody 2G12 produced in maize endosperm efficiently neutralizes HIV-1 and contains predominantly single-GlcNAc N-glycans","volume":"6","author":"Rademacher","year":"2008","journal-title":"Plant Biotechnol. J."},{"key":"10.1016\/j.tplants.2020.04.009_bb0205","doi-asserted-by":"crossref","first-page":"3727","DOI":"10.1073\/pnas.0708841104","article-title":"Cost-effective production of a vaginal protein microbicide to prevent HIV transmission","volume":"105","author":"Ramessar","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tplants.2020.04.009_bb0210","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/pbi.12360","article-title":"Rice endosperm produces an underglycosylated and potent form of the HIV-neutralizing monoclonal antibody 2G12","volume":"14","author":"Vamvaka","year":"2016","journal-title":"Plant Biotechnol. J."},{"key":"10.1016\/j.tplants.2020.04.009_bb0215","doi-asserted-by":"crossref","first-page":"E7854","DOI":"10.1073\/pnas.1806022115","article-title":"Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm","volume":"115","author":"Vamvaka","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tplants.2020.04.009_bb0220","series-title":"Northwell Health Initiates Clinical Trials of 2 COVID-19 Drugs","author":"Long Island Press","year":"2020"},{"key":"10.1016\/j.tplants.2020.04.009_bb0225","series-title":"WHO and Roche Launch Trials of Potential Coronavirus Treatments","author":"Swiss Broadcasting Corporation","year":"2020"},{"key":"10.1016\/j.tplants.2020.04.009_bb0230","doi-asserted-by":"crossref","first-page":"3750646","DOI":"10.1155\/2018\/3750646","article-title":"Lectins as promising therapeutics for the prevention and treatment of HIV and other potential coinfections","volume":"2018","author":"Mazalovska","year":"2018","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.tplants.2020.04.009_bb0235","doi-asserted-by":"crossref","first-page":"9345","DOI":"10.1074\/jbc.M411122200","article-title":"Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp","volume":"280","author":"Mori","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.tplants.2020.04.009_bb0240","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1128\/AAC.01407-13","article-title":"Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models","volume":"58","author":"Barton","year":"2014","journal-title":"Antimicr. Ag. Chemother."},{"key":"10.1016\/j.tplants.2020.04.009_bb0245","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1128\/JVI.02322-09","article-title":"Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae","volume":"84","author":"O'Keefe","year":"2010","journal-title":"J. Virol."},{"key":"10.1016\/j.tplants.2020.04.009_bb0250","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.antiviral.2016.07.011","article-title":"Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin","volume":"133","author":"Millet","year":"2016","journal-title":"Antiviral Res."},{"key":"10.1016\/j.tplants.2020.04.009_bb0255","doi-asserted-by":"crossref","first-page":"2578","DOI":"10.1021\/bi0205698","article-title":"A potent novel anti-HIV protein from the cultured cyanobacterium Scytonema varium","volume":"42","author":"Bokesch","year":"2003","journal-title":"Biochemistry"},{"key":"10.1016\/j.tplants.2020.04.009_bb0260","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.antiviral.2014.09.012","article-title":"The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus","volume":"112","author":"Garrison","year":"2014","journal-title":"Antiviral Res."},{"key":"10.1016\/j.tplants.2020.04.009_bb0265","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.antiviral.2007.03.003","article-title":"Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycle","volume":"75","author":"Keyaerts","year":"2007","journal-title":"Antiviral Res."},{"key":"10.1016\/j.tplants.2020.04.009_bb0270","doi-asserted-by":"crossref","first-page":"6099","DOI":"10.1073\/pnas.0901506106","article-title":"Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component","volume":"106","author":"O\u2019Keefe","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.tplants.2020.04.009_bb0275","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1111\/pbi.12507","article-title":"Rice endosperm is cost-effective for the production of recombinant griffithsin with potent activity against HIV","volume":"14","author":"Vamvaka","year":"2016","journal-title":"Plant Biotechnol. J."},{"key":"10.1016\/j.tplants.2020.04.009_bb0280","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1096\/fj.05-4742fje","article-title":"Transgenic plant production of cyanovirin-N, an HIV microbicide","volume":"20","author":"Sexton","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.tplants.2020.04.009_bb0285","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1007\/s11248-013-9730-7","article-title":"Transformation of Althaea officinalis L. by Agrobacterium rhizogenes for the production of transgenic roots expressing the anti-HIV microbicide cyanovirin-N","volume":"22","author":"Drake","year":"2013","journal-title":"Transgenic Res."},{"key":"10.1016\/j.tplants.2020.04.009_bb0290","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1111\/pbi.12309","article-title":"Engineering soya bean seeds as a scalable platform to produce cyanovirin-N, a non-ARV microbicide against HIV","volume":"13","author":"O\u2019Keefe","year":"2015","journal-title":"Plant Biotechnol. J."},{"key":"10.1016\/j.tplants.2020.04.009_bb0295","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1007\/s00299-016-1963-5","article-title":"Cyanovirin-N produced in rice endosperm offers effective pre-exposure prophylaxis against HIV-1BaL infection in vitro","volume":"35","author":"Vamvaka","year":"2016","journal-title":"Plant Cell Rep."},{"key":"10.1016\/j.tplants.2020.04.009_bb0300","doi-asserted-by":"crossref","first-page":"3590","DOI":"10.1096\/fj.09-131995","article-title":"Design, expression, and characterization of a multivalent, combination HIV microbicide","volume":"23","author":"Sexton","year":"2009","journal-title":"FASEB J."},{"key":"10.1016\/j.tplants.2020.04.009_bb0305","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1038\/sj.embor.7400470","article-title":"Molecular farming for new drugs and vaccines. Current perspectives on the production of pharmaceuticals in transgenic plants","volume":"6","author":"Ma","year":"2005","journal-title":"EMBO Rep."},{"key":"10.1016\/j.tplants.2020.04.009_bb0310","doi-asserted-by":"crossref","first-page":"5478","DOI":"10.2174\/1381612811319310003","article-title":"Target product selection - where can Molecular Pharming make the difference?","volume":"19","author":"Paul","year":"2013","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.tplants.2020.04.009_bb0315","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s11248-007-9074-2","article-title":"Pharma-Planta: road testing the developing regulatory guidelines for plant-made pharmaceuticals","volume":"16","author":"Sparrow","year":"2007","journal-title":"Transgenic Res."}],"container-title":["Trends in Plant Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1360138520301242?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1360138520301242?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T18:12:00Z","timestamp":1761243120000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1360138520301242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":63,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["S1360138520301242"],"URL":"https:\/\/doi.org\/10.1016\/j.tplants.2020.04.009","relation":{},"ISSN":["1360-1385"],"issn-type":[{"value":"1360-1385","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Potential Applications of Plant Biotechnology against SARS-CoV-2","name":"articletitle","label":"Article Title"},{"value":"Trends in Plant Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tplants.2020.04.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}