{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T20:18:45Z","timestamp":1776802725758,"version":"3.51.2"},"reference-count":22,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL121415"],"award-info":[{"award-number":["R01HL121415"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL130139"],"award-info":[{"award-number":["R01HL130139"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Clinique et Biologique"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.tracli.2019.02.004","type":"journal-article","created":{"date-parts":[[2019,2,22]],"date-time":"2019-02-22T19:14:52Z","timestamp":1550862892000},"page":"128-129","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Patrolling monocytes in sickle cell hemolytic conditions"],"prefix":"10.1016","volume":"26","author":[{"given":"Y.","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Vinchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mendelson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Yazdanbakhsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tracli.2019.02.004_bib0115","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1016\/S0140-6736(16)00647-4","article-title":"Cardiovascular complications and risk of death in sickle-cell disease","volume":"387","author":"Gladwin","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.tracli.2019.02.004_bib0120","doi-asserted-by":"crossref","first-page":"3892","DOI":"10.1182\/blood-2013-05-498311","article-title":"Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies","volume":"122","author":"Manwani","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.tracli.2019.02.004_bib0125","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/10739680490278402","article-title":"The endothelial biology of sickle cell disease: inflammation and a chronic vasculopathy","volume":"11","author":"Hebbel","year":"2004","journal-title":"Microcirculation"},{"key":"10.1016\/j.tracli.2019.02.004_bib0130","first-page":"316","article-title":"Extracorpuscular factors in the pathogenesis of sickle cell disease","volume":"4","author":"Hebbel","year":"1982","journal-title":"Am J Pediatr Hematol Oncol"},{"key":"10.1016\/j.tracli.2019.02.004_bib0135","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1172\/JCI9225","article-title":"Hypoxia\/reoxygenation causes inflammatory response in transgenic sickle mice but not in normal mice","volume":"106","author":"Kaul","year":"2000","journal-title":"J Clin Invest"},{"key":"10.1016\/j.tracli.2019.02.004_bib0140","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1172\/JCI89741","article-title":"Intravascular hemolysis and the pathophysiology of sickle cell disease","volume":"127","author":"Kato","year":"2017","journal-title":"J Clin Invest"},{"key":"10.1016\/j.tracli.2019.02.004_bib0145","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1161\/CIRCULATIONAHA.112.130179","article-title":"Hemopexin therapy improves cardiovascular function by preventing heme-induced endothelial toxicity in mouse models of hemolytic diseases","volume":"127","author":"Vinchi","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.tracli.2019.02.004_bib0150","doi-asserted-by":"crossref","first-page":"e0196455","DOI":"10.1371\/journal.pone.0196455","article-title":"Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction","volume":"13","author":"Belcher","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.tracli.2019.02.004_bib0155","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1146\/annurev.pharmtox.010909.105600","article-title":"Mechanisms of cell protection by heme oxygenase-1","volume":"50","author":"Gozzelino","year":"2010","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"10.1016\/j.tracli.2019.02.004_bib0160","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1089\/ars.2010.3726","article-title":"A central role of heme oxygenase-1 in cardiovascular protection","volume":"15","author":"Wu","year":"2011","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.tracli.2019.02.004_bib0165","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1172\/JCI26857","article-title":"Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice","volume":"116","author":"Belcher","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.tracli.2019.02.004_bib0170","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1089\/ars.2010.3153","article-title":"Heme oxygenase in the regulation of vascular biology: from molecular mechanisms to therapeutic opportunities","volume":"14","author":"Kim","year":"2011","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.tracli.2019.02.004_bib0175","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1161\/ATVBAHA.109.196360","article-title":"Human sickle cell blood modulates endothelial heme oxygenase activity: effects on vascular adhesion and reactivity","volume":"30","author":"Bains","year":"2010","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.tracli.2019.02.004_bib0180","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/s00109-010-0613-6","article-title":"Heme oxygenase-1 gene delivery by Sleeping Beauty inhibits vascular stasis in a murine model of sickle cell disease","volume":"88","author":"Belcher","year":"2010","journal-title":"J Mol Med (Berl)"},{"key":"10.1016\/j.tracli.2019.02.004_bib0185","doi-asserted-by":"crossref","first-page":"102","DOI":"10.4049\/jimmunol.1400105","article-title":"Hemin controls T cell polarization in sickle cell alloimmunization","volume":"193","author":"Zhong","year":"2014","journal-title":"J Immunol"},{"key":"10.1016\/j.tracli.2019.02.004_bib0190","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1365-2249.2005.02932.x","article-title":"Selective expansion of CD16highCCR2- subpopulation of circulating monocytes with preferential production of haem oxygenase (HO)-1 in response to acute inflammation","volume":"142","author":"Mizuno","year":"2005","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.tracli.2019.02.004_bib0195","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1126\/science.1178331","article-title":"Development of monocytes, macrophages, and dendritic cells","volume":"327","author":"Geissmann","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.tracli.2019.02.004_bib0200","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.cell.2013.03.010","article-title":"Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal","volume":"153","author":"Carlin","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.tracli.2019.02.004_bib0205","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1161\/CIRCRESAHA.117.310739","article-title":"Endothelial Protective Monocyte Patrolling in Large Arteries Intensified by Western Diet and Atherosclerosis","volume":"120","author":"Quintar","year":"2017","journal-title":"Circ Res"},{"key":"10.1016\/j.tracli.2019.02.004_bib0210","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.celrep.2013.10.010","article-title":"Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta","volume":"5","author":"Michaud","year":"2013","journal-title":"Cell Rep"},{"key":"10.1016\/j.tracli.2019.02.004_bib0215","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1182\/blood-2017-12-819870","article-title":"HO-1(hi) patrolling monocytes protect against vaso-occlusion in sickle cell disease","volume":"131","author":"Liu","year":"2018","journal-title":"Blood"},{"key":"10.1016\/j.tracli.2019.02.004_bib0220","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1182\/blood-2018-02-832139","article-title":"Patrolling the endothelium in sickle cell disease","volume":"131","author":"Gordeuk","year":"2018","journal-title":"Blood"}],"container-title":["Transfusion Clinique et Biologique"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1246782019300321?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1246782019300321?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:38:06Z","timestamp":1761129486000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1246782019300321"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["S1246782019300321"],"URL":"https:\/\/doi.org\/10.1016\/j.tracli.2019.02.004","relation":{},"ISSN":["1246-7820"],"issn-type":[{"value":"1246-7820","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Patrolling monocytes in sickle cell hemolytic conditions","name":"articletitle","label":"Article Title"},{"value":"Transfusion Clinique et Biologique","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tracli.2019.02.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}