{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T20:16:36Z","timestamp":1788034596140,"version":"build-2784847793"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Clinique et Biologique"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.tracli.2026.07.005","type":"journal-article","created":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T15:34:41Z","timestamp":1786721681000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical utility of LLM-assisted chart review for the detection of bleeding events"],"prefix":"10.1016","author":[{"given":"Merijn C.","family":"Reuland","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar M.","family":"van der Meer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Testoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter O.L.P.","family":"Broeren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dave A.","family":"Dongelmans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul W.G.","family":"Elbers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcella C.A.","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Senta Jorinde","family":"Raasveld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander P.J.","family":"Vlaar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tracli.2026.07.005_bib0135","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1001\/jama.2023.20737","article-title":"Red Blood Cell Transfusion in the Intensive Care Unit","volume":"330","author":"Raasveld","year":"2023","journal-title":"JAMA"},{"key":"10.1016\/j.tracli.2026.07.005_bib0140","doi-asserted-by":"crossref","DOI":"10.1186\/s13054-022-04171-1","article-title":"Association between in-ICU red blood cells transfusion and 1-year mortality in ICU survivors","volume":"26","author":"Blet","year":"2022","journal-title":"Crit Care"},{"key":"10.1016\/j.tracli.2026.07.005_bib0145","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/01.CCM.0000104112.34142.79","article-title":"The CRIT Study: anemia and blood transfusion in the critically ill\u2014Current clinical practice in the United States","volume":"32","author":"Corwin","year":"2004","journal-title":"Crit Care Med"},{"key":"10.1016\/j.tracli.2026.07.005_bib0150","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/s13054-018-2018-9","article-title":"Worldwide audit of blood transfusion practice in critically ill patients","volume":"22","author":"Vincent","year":"2018","journal-title":"Crit Care"},{"key":"10.1016\/j.tracli.2026.07.005_bib0155","doi-asserted-by":"crossref","first-page":"155352","DOI":"10.1016\/j.jcrc.2025.155352","article-title":"Nationwide expert survey on transfusion and coagulation management strategies for bleeding critically ill patients in China","volume":"92","author":"Chen","year":"2026","journal-title":"J Crit Care"},{"key":"10.1016\/j.tracli.2026.07.005_bib0160","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1111\/j.1538-7836.2012.04923.x","article-title":"The evolution and value of bleeding assessment tools","volume":"10","author":"Rydz","year":"2012","journal-title":"J Thrombosis Haemostasis"},{"key":"10.1016\/j.tracli.2026.07.005_bib0165","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1185\/03007995.2011.644849","article-title":"Selective validation of the WHO Bleeding Scale in patients with chronic immune thrombocytopenia","volume":"28","author":"Fogarty","year":"2012","journal-title":"Curr Med Res Opinion"},{"key":"10.1016\/j.tracli.2026.07.005_bib0170","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/trf.16126","article-title":"Exploring the components of bleeding outcomes in transfusion trials for patients with hematologic malignancy","volume":"61","author":"Balitsky","year":"2021","journal-title":"Transfusion"},{"key":"10.1016\/j.tracli.2026.07.005_bib0175","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/vox.12627","article-title":"A multicentred study to validate a consensus bleeding assessment tool developed by the biomedical excellence for safer transfusion claborative for use in patients with haematological malignancy","volume":"113","author":"Dyer","year":"2018","journal-title":"Vox Sanguinis"},{"key":"10.1016\/j.tracli.2026.07.005_bib0180","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.thromres.2022.05.013","article-title":"Interrater agreement of two scales on the severity of anticoagulantrelated major bleeding in patients with venous thromboembolism","volume":"216","author":"Guman","year":"2022","journal-title":"Thrombosis Res"},{"key":"10.1016\/j.tracli.2026.07.005_bib0185","article-title":"Bleeding during critical illness: a prospective cohort study using a new measurement tool","volume":"30","author":"Arnold","year":"2007","journal-title":"Clin Investig Med"},{"key":"10.1016\/j.tracli.2026.07.005_bib0190","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1186\/s13054-025-05532-2","article-title":"Implementing Artificial Intelligence in Critical Care Medicine: a consensus of 22","volume":"29","author":"Cecconi","year":"2025","journal-title":"Crit Care"},{"key":"10.1016\/j.tracli.2026.07.005_bib0195","doi-asserted-by":"crossref","DOI":"10.1038\/s41746-025-01896-5","article-title":"Usability and adoption in a randomized trial of GutGPT a GenAI tool for gastrointestinal bleeding","volume":"8","author":"Chung","year":"2025","journal-title":"NPJ Digital Med"},{"key":"10.1016\/j.tracli.2026.07.005_bib0200","doi-asserted-by":"crossref","unstructured":"Rajabnia M., Davoodi F., Hajisafarali M., Asadinia S., Shiri M., Shirzad F., et al. Evaluation of large language models in the clinical management of patients with upper gastrointestinal bleeding: insights from real-world patient data. 2025. Available from: http:\/\/medrxiv.org\/lookup\/doi\/10.1101\/2025.11.10.25339858.","DOI":"10.1101\/2025.11.10.25339858"},{"key":"10.1016\/j.tracli.2026.07.005_bib0205","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3343\/alm.2025.0422","article-title":"Large language model advances in transfusion medicine: from answering questions to supporting clinical decisions","volume":"45","author":"Ahn","year":"2025","journal-title":"Ann Lab Med"},{"key":"10.1016\/j.tracli.2026.07.005_bib0210","doi-asserted-by":"crossref","first-page":"520","DOI":"10.3343\/alm.2024.0588","article-title":"Evaluation of six large language models for clinical decision support: application in transfusion decision making for RhD blood-type patients","volume":"45","author":"Lee","year":"2025","journal-title":"Ann Lab Med"},{"key":"10.1016\/j.tracli.2026.07.005_bib0215","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1053\/j.gastro.2024.09.014","article-title":"Detection of gastrointestinal bleeding with large language models to aid quality improvement and appropriate reimbursement","volume":"168","author":"Zheng","year":"2025","journal-title":"Gastroenterology"},{"key":"10.1016\/j.tracli.2026.07.005_bib0220","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1182\/blood-2024-203911","article-title":"Retrieval augmented generation for the detection of major bleeding events in the electronic health record","volume":"144","author":"Kaplinsky","year":"2024","journal-title":"Blood"},{"key":"10.1016\/j.tracli.2026.07.005_bib0225","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1182\/blood-2025-1073","article-title":"Evaluating gpt-4 for zero-shot classification of bleeding and clotting events: can large language models serve as second reviewers?","volume":"146","author":"Rizzo","year":"2025","journal-title":"Blood"},{"key":"10.1016\/j.tracli.2026.07.005_bib0230","first-page":"19","article-title":"Discordance and bleeding in critically ill patients with COVID-19 receiving unfractionated heparin: a comparison between aPTT and anti-factor Xa activity level monitoring","volume":"6","author":"Reuland","year":"2025","journal-title":"Thrombosis Update"},{"key":"10.1016\/j.tracli.2026.07.005_bib0235","unstructured":"R Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria. 2025. Available from: https:\/\/www.R-project.org\/."},{"key":"10.1016\/j.tracli.2026.07.005_bib0240","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/s41591-024-03425-5","article-title":"The TRIPOD-LLM reporting guideline for studies using large language models","volume":"31","author":"Gallifant","year":"2025","journal-title":"Nat Med"},{"key":"10.1016\/j.tracli.2026.07.005_bib0245","doi-asserted-by":"crossref","first-page":"e183451","DOI":"10.1001\/jamanetworkopen.2018.3451","article-title":"Comparison of 2 natural language processing methods for identification of bleeding among critically ill patients","volume":"1","author":"Taggart","year":"2018","journal-title":"JAMA Network Open"},{"key":"10.1016\/j.tracli.2026.07.005_bib0250","doi-asserted-by":"crossref","DOI":"10.1038\/s41746-023-00957-x","article-title":"Zero-shot interpretable phenotyping of postpartum hemorrhage using large language models","volume":"6","author":"Alsentzer","year":"2023","journal-title":"NPJ Digital Med"},{"key":"10.1016\/j.tracli.2026.07.005_bib0255","doi-asserted-by":"crossref","DOI":"10.1097\/og9.0000000000000128","article-title":"Predicting postpartum hemorrhage using clinical features extracted with large language models","volume":"2","author":"Woo","year":"2025","journal-title":"O&G Open"},{"key":"10.1016\/j.tracli.2026.07.005_bib0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.xops.2024.100602","article-title":"ChatGPT-assisted classification of postoperative bleeding following microinvasive glaucoma surgery using electronic health record data","volume":"5","author":"Shaheen","year":"2025","journal-title":"Ophthalmol Sci"}],"container-title":["Transfusion Clinique et Biologique"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1246782026001163?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1246782026001163?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T19:28:11Z","timestamp":1788031691000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1246782026001163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":26,"alternative-id":["S1246782026001163"],"URL":"https:\/\/doi.org\/10.1016\/j.tracli.2026.07.005","relation":{},"ISSN":["1246-7820"],"issn-type":[{"value":"1246-7820","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical utility of LLM-assisted chart review for the detection of bleeding events","name":"articletitle","label":"Article Title"},{"value":"Transfusion Clinique et Biologique","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tracli.2026.07.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Masson SAS on behalf of Soci\u00e9t\u00e9 francophone de transfusion sanguine (SFTS).","name":"copyright","label":"Copyright"}]}}