{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T13:41:49Z","timestamp":1788615709025,"version":"build-2803163510"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,27]],"date-time":"2024-04-27T00:00:00Z","timestamp":1714176000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Translational Oncology"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.tranon.2024.101979","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T17:12:17Z","timestamp":1715274737000},"page":"101979","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Retinol-binding protein 4 as a promising serum biomarker for the diagnosis and prognosis of hepatocellular Carcinoma"],"prefix":"10.1016","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8878-8979","authenticated-orcid":false,"given":"Fengjie","family":"Wan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujia","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feixiang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuejing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongtao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lifang","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lirong","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.tranon.2024.101979_bib0001","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J. Clin."},{"issue":"Suppl 1","key":"10.1016\/j.tranon.2024.101979_bib0002","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/hep.31288","article-title":"El-Serag HB. epidemiology of hepatocellular carcinoma","volume":"73 Suppl 1","author":"McGlynn","year":"2021","journal-title":"Hepatology"},{"issue":"12","key":"10.1016\/j.tranon.2024.101979_bib0003","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1001\/jamaoncol.2017.3055","article-title":"The Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level: results From the Global Burden of Disease Study 2015","volume":"3","author":"Akinyemiju","year":"2017","journal-title":"JAMa Oncol."},{"issue":"10125","key":"10.1016\/j.tranon.2024.101979_bib0004","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0140-6736(17)33326-3","article-title":"Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries","volume":"391","author":"Allemani","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.tranon.2024.101979_bib0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/bs.acr.2020.10.001","article-title":"Hepatocellular carcinoma (HCC): epidemiology, etiology and molecular classification","volume":"149","author":"Chidambaranathan-Reghupaty","year":"2021","journal-title":"Adv. Cancer Res."},{"issue":"4","key":"10.1016\/j.tranon.2024.101979_bib0006","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1042\/BSR20210328","article-title":"Down-regulation of RBP4indicates a poor prognosis and correlates with immune cell infiltration in hepatocellular carcinoma","volume":"41","author":"Li","year":"2021","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.tranon.2024.101979_bib0007","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1471-2407-7-28","article-title":"The progressive elevation of alpha fetoprotein for the diagnosis of hepatocellular carcinoma in patients with liver cirrhosis","volume":"7","author":"Arrieta","year":"2007","journal-title":"BMC Cancer"},{"issue":"4","key":"10.1016\/j.tranon.2024.101979_bib0008","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s12072-015-9651-z","article-title":"Predicting clinical outcomes in patients with HBsAg-positive chronic hepatitis","volume":"9","author":"Tong","year":"2015","journal-title":"Hepatol. Int."},{"issue":"37","key":"10.1016\/j.tranon.2024.101979_bib0009","doi-asserted-by":"crossref","first-page":"10573","DOI":"10.3748\/wjg.v21.i37.10573","article-title":"Biomarkers for the early diagnosis of hepatocellular carcinoma","volume":"21","author":"Tsuchiya","year":"2015","journal-title":"World J. Gastroenterol."},{"issue":"1","key":"10.1016\/j.tranon.2024.101979_bib0010","doi-asserted-by":"crossref","first-page":"46","DOI":"10.7326\/0003-4819-139-1-200307010-00012","article-title":"Test characteristics of alpha-fetoprotein for detecting hepatocellular carcinoma in patients with hepatitis C. A systematic review and critical analysis","volume":"139","author":"Gupta","year":"2003","journal-title":"Ann. Intern. Med."},{"issue":"39","key":"10.1016\/j.tranon.2024.101979_bib0011","doi-asserted-by":"crossref","first-page":"6115","DOI":"10.3748\/wjg.v11.i39.6115","article-title":"Usefulness of serum des-gamma-carboxy prothrombin in detection of hepatocellular carcinoma","volume":"11","author":"Wang","year":"2005","journal-title":"World J. Gastroenterol."},{"issue":"1","key":"10.1016\/j.tranon.2024.101979_bib0012","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s12072-007-9038-x","article-title":"Diagnostic accuracy of tumor markers for hepatocellular carcinoma: a systematic review","volume":"2","author":"Tateishi","year":"2008","journal-title":"Hepatol. Int."},{"issue":"6","key":"10.1016\/j.tranon.2024.101979_bib0013","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/S0016-5085(84)80151-1","article-title":"Serum alpha-fetoprotein in the early stage of human hepatocellular carcinoma","volume":"86","author":"Chen","year":"1984","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.tranon.2024.101979_bib0014","doi-asserted-by":"crossref","first-page":"12870","DOI":"10.1038\/s41598-017-12834-1","article-title":"The prognostic correlation of AFP level at diagnosis with pathological grade, progression, and survival of patients with hepatocellular carcinoma","volume":"7","author":"Bai","year":"2017","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.tranon.2024.101979_bib0015","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1158\/1078-0432.CCR-07-0586","article-title":"Serum proteomics and biomarkers in hepatocellular carcinoma and chronic liver disease","volume":"14","author":"Zinkin","year":"2008","journal-title":"Clin. Cancer Res."},{"issue":"5 Suppl 1","key":"10.1016\/j.tranon.2024.101979_bib0016","doi-asserted-by":"crossref","first-page":"S120","DOI":"10.1053\/j.gastro.2004.09.025","article-title":"Proteomics for hepatocellular carcinoma marker discovery","volume":"127","author":"Chignard","year":"2004","journal-title":"Gastroenterology"},{"issue":"13","key":"10.1016\/j.tranon.2024.101979_bib0017","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1002\/pmic.201400364","article-title":"LC-MS\/MS-based serum proteomics for identification of candidate biomarkers for hepatocellular carcinoma","volume":"15","author":"Tsai","year":"2015","journal-title":"Proteomics"},{"issue":"4","key":"10.1016\/j.tranon.2024.101979_bib0018","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1021\/pr3011815","article-title":"Quantitative proteomic analysis identified paraoxonase 1 as a novel serum biomarker for microvascular invasion in hepatocellular carcinoma","volume":"12","author":"Huang","year":"2013","journal-title":"J. Proteome Res."},{"issue":"8","key":"10.1016\/j.tranon.2024.101979_bib0019","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/S1470-2045(12)70233-4","article-title":"Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study","volume":"13","author":"Shen","year":"2012","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.tranon.2024.101979_bib0020","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ebiom.2017.09.007","article-title":"Plasma heat shock protein 90alpha as a biomarker for the diagnosis of liver cancer: an official, large-scale, and multicenter clinical trial","volume":"24","author":"Fu","year":"2017","journal-title":"EBioMedicine"},{"key":"10.1016\/j.tranon.2024.101979_bib0021","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ebiom.2017.10.012","article-title":"Plasma HSP90alpha and liver cancer: a potential biomarker?","volume":"25","author":"Sourbier","year":"2017","journal-title":"EBioMedicine"},{"issue":"14","key":"10.1016\/j.tranon.2024.101979_bib0022","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1093\/jnci\/93.14.1054","article-title":"Phases of biomarker development for early detection of cancer","volume":"93","author":"Pepe","year":"2001","journal-title":"J. Natl. Cancer Inst."},{"issue":"9","key":"10.1016\/j.tranon.2024.101979_bib0023","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1111\/liv.12818","article-title":"Global patterns of hepatocellular carcinoma management from diagnosis to death: the BRIDGE study","volume":"35","author":"Park","year":"2015","journal-title":"Liver. Int."},{"issue":"1","key":"10.1016\/j.tranon.2024.101979_bib0024","doi-asserted-by":"crossref","first-page":"17","DOI":"10.4149\/neo_2014_001","article-title":"Screening differential expression of serum proteins in AFP-negative HBV-related hepatocellular carcinoma using iTRAQ -MALDI-MS\/MS","volume":"61","author":"He","year":"2014","journal-title":"Neoplasma"},{"issue":"8","key":"10.1016\/j.tranon.2024.101979_bib0025","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.neo.2017.05.002","article-title":"UALCAN: a portal for facilitating tumor subgroup gene expression and survival analyses","volume":"19","author":"Chandrashekar","year":"2017","journal-title":"Neoplasia"},{"key":"10.1016\/j.tranon.2024.101979_bib0026","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/7651_2017_112","article-title":"Multiple reaction monitoring using double isotopologue peptide standards for protein quantification","volume":"1788","author":"Eshghi","year":"2018","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.tranon.2024.101979_bib0027","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1479-5876-11-59","article-title":"Low expression of PTK6\/Brk predicts poor prognosis in patients with laryngeal squamous cell carcinoma","volume":"11","author":"Liu","year":"2013","journal-title":"J. Transl. Med."},{"issue":"2","key":"10.1016\/j.tranon.2024.101979_bib0028","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1586\/14789450.2014.877346","article-title":"MRM for the verification of cancer biomarker proteins: recent applications to human plasma and serum","volume":"11","author":"Chambers","year":"2014","journal-title":"Expert. Rev. Proteomics"},{"issue":"12","key":"10.1016\/j.tranon.2024.101979_bib0029","doi-asserted-by":"crossref","first-page":"2650","DOI":"10.1016\/j.jprot.2011.04.011","article-title":"Targeted mass spectrometry approaches for protein biomarker verification","volume":"74","author":"Meng","year":"2011","journal-title":"J. Proteomics"},{"issue":"7","key":"10.1016\/j.tranon.2024.101979_bib0030","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s00432-004-0552-0","article-title":"Randomized controlled trial of screening for hepatocellular carcinoma","volume":"130","author":"Zhang","year":"2004","journal-title":"J. Cancer Res. Clin. Oncol."},{"issue":"9","key":"10.1016\/j.tranon.2024.101979_bib0031","first-page":"1668","article-title":"Evaluation of diagnostic efficiency of alpha-fetoprotein in patients with liver cirrhosis and hepatocellular carcinoma: single-center experience. open access maced","volume":"6","author":"Mehinovic","year":"2018","journal-title":"J. Med. Sci."},{"issue":"2","key":"10.1016\/j.tranon.2024.101979_bib0032","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1053\/jhep.2002.34744","article-title":"Racial differences in effectiveness of alpha-fetoprotein for diagnosis of hepatocellular carcinoma in hepatitis C virus cirrhosis","volume":"36","author":"Nguyen","year":"2002","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.tranon.2024.101979_bib0033","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1111\/j.1572-0241.2006.00443.x","article-title":"Diagnostic and prognostic role of alpha-fetoprotein in hepatocellular carcinoma: both or neither?","volume":"101","author":"Farinati","year":"2006","journal-title":"Am. J. Gastroenterol."},{"issue":"3","key":"10.1016\/j.tranon.2024.101979_bib0034","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1210\/edrv-10-3-308","article-title":"Retinol-binding protein: the serum transport protein for vitamin A","volume":"10","author":"Blaner","year":"1989","journal-title":"Endocr. Rev."},{"issue":"7049","key":"10.1016\/j.tranon.2024.101979_bib0035","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/nature03711","article-title":"Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes","volume":"436","author":"Yang","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.tranon.2024.101979_bib0036","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s12986-018-0329-0","article-title":"Retinol binding protein 4 and risk of type 2 diabetes in Singapore Chinese men and women: a nested case-control study","volume":"16","author":"Wang","year":"2019","journal-title":"Nutr. Metab."},{"issue":"17\u201318","key":"10.1016\/j.tranon.2024.101979_bib0037","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1016\/j.clinbiochem.2011.08.1148","article-title":"Plasma visfatin and retinol binding protein-4 levels in patients with type 2 diabetes mellitus and their relationship to adiposity and fatty liver","volume":"44","author":"Shaker","year":"2011","journal-title":"Clin. Biochem."},{"issue":"6","key":"10.1016\/j.tranon.2024.101979_bib0038","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1002\/ijc.30818","article-title":"The association between individual metabolic syndrome components, primary liver cancer and cirrhosis: a study in the Swedish AMORIS cohort","volume":"141","author":"Nderitu","year":"2017","journal-title":"Int. J. Cancer"},{"issue":"5","key":"10.1016\/j.tranon.2024.101979_bib0039","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1530\/EJE-11-0431","article-title":"RBP4: a controversial adipokine","volume":"165","author":"Kotnik","year":"2011","journal-title":"Eur. J. Endocrinol."},{"issue":"2","key":"10.1016\/j.tranon.2024.101979_bib0040","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1007\/s00125-015-3807-1","article-title":"RBP4 functions as a hepatokine in the regulation of glucose metabolism by the circadian clock in mice","volume":"59","author":"Ma","year":"2016","journal-title":"Diabetologia"},{"issue":"9","key":"10.1016\/j.tranon.2024.101979_bib0041","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/j.exphem.2004.06.006","article-title":"The comparative analysis of serum proteomes for the discovery of biomarkers for acute myeloid leukemia","volume":"32","author":"Kwak","year":"2004","journal-title":"Exp. Hematol."},{"issue":"2","key":"10.1016\/j.tranon.2024.101979_bib0042","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1515\/hmbci-2015-0019","article-title":"Is retinol binding protein 4 a link between adiposity and cancer?","volume":"23","author":"Noy","year":"2015","journal-title":"Horm. Mol. Biol. Clin. Investig."},{"issue":"1","key":"10.1016\/j.tranon.2024.101979_bib0043","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s13048-018-0397-9","article-title":"Adipokine RBP4 drives ovarian cancer cell migration","volume":"11","author":"Wang","year":"2018","journal-title":"J. Ovarian. Res."},{"issue":"54","key":"10.1016\/j.tranon.2024.101979_bib0044","doi-asserted-by":"crossref","first-page":"92254","DOI":"10.18632\/oncotarget.21173","article-title":"RBP4 and THBS2 are serum biomarkers for diagnosis of colorectal cancer","volume":"8","author":"Fei","year":"2017","journal-title":"Oncotarget"},{"issue":"2","key":"10.1016\/j.tranon.2024.101979_bib0045","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.stemcr.2017.06.002","article-title":"RBP4-STRA6 pathway drives cancer stem cell maintenance and mediates high-fat diet-induced colon carcinogenesis","volume":"9","author":"Karunanithi","year":"2017","journal-title":"Stem Cell Rep."},{"issue":"12","key":"10.1016\/j.tranon.2024.101979_bib0046","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0167498","article-title":"Elevated serum levels of retinol-binding protein 4 are associated with breast cancer risk: a case-control study","volume":"11","author":"Jiao","year":"2016","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.tranon.2024.101979_bib0047","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1053\/jhep.2002.34851","article-title":"Underexpression of mRNA in human hepatocellular carcinoma focusing on eight loci","volume":"36","author":"Kinoshita","year":"2002","journal-title":"Hepatology"},{"issue":"13","key":"10.1016\/j.tranon.2024.101979_bib0048","doi-asserted-by":"crossref","first-page":"9694","DOI":"10.1074\/jbc.M111.301721","article-title":"Increased unbound retinol-binding protein 4 concentration induces apoptosis through receptor-mediated signaling","volume":"287","author":"Chen","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.tranon.2024.101979_bib0049","doi-asserted-by":"crossref","first-page":"741","DOI":"10.15252\/emmm.201607222","article-title":"Hepatic stellate cells limit hepatocellular carcinoma progression through the orphan receptor endosialin","volume":"9","author":"Mogler","year":"2017","journal-title":"EMBo Mol. Med."},{"issue":"11","key":"10.1016\/j.tranon.2024.101979_bib0050","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.2337\/db09-0216","article-title":"Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance","volume":"58","author":"Deng","year":"2009","journal-title":"Diabetes"},{"issue":"4","key":"10.1016\/j.tranon.2024.101979_bib0051","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20210328","article-title":"Down-regulation of RBP4 indicates a poor prognosis and correlates with immune cell infiltration in hepatocellular carcinoma","volume":"41","author":"Li","year":"2021","journal-title":"Biosci. Rep."},{"issue":"6","key":"10.1016\/j.tranon.2024.101979_bib0052","doi-asserted-by":"crossref","first-page":"401","DOI":"10.2188\/jea.JE20100190","article-title":"Hepatitis B and C virus infection and hepatocellular carcinoma in China: a review of epidemiology and control measures","volume":"21","author":"Tanaka","year":"2011","journal-title":"J. Epidemiol."},{"issue":"10","key":"10.1016\/j.tranon.2024.101979_bib0053","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/s41575-019-0186-y","article-title":"A global view of hepatocellular carcinoma: trends, risk, prevention and management","volume":"16","author":"Yang","year":"2019","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"Pt 8","key":"10.1016\/j.tranon.2024.101979_bib0054","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1099\/vir.0.062430-0","article-title":"Serum proteomics of hepatitis C virus infection reveals retinol-binding protein 4 as a novel regulator","volume":"95","author":"Gouthamchandra","year":"2014","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.tranon.2024.101979_bib0055","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s12876-016-0432-5","article-title":"Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer","volume":"16","author":"Kataria","year":"2016","journal-title":"BMC. Gastroenterol."},{"issue":"4","key":"10.1016\/j.tranon.2024.101979_bib0056","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1007\/s00432-010-0927-3","article-title":"Preoperative serum retinol-binding protein 4 is associated with the prognosis of patients with hepatocellular carcinoma after curative resection","volume":"137","author":"Wang","year":"2011","journal-title":"J. Cancer Res. Clin. Oncol."}],"container-title":["Translational Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936523324001062?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936523324001062?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T09:22:05Z","timestamp":1716369725000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936523324001062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":56,"alternative-id":["S1936523324001062"],"URL":"https:\/\/doi.org\/10.1016\/j.tranon.2024.101979","relation":{},"ISSN":["1936-5233"],"issn-type":[{"value":"1936-5233","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Retinol-binding protein 4 as a promising serum biomarker for the diagnosis and prognosis of hepatocellular Carcinoma","name":"articletitle","label":"Article Title"},{"value":"Translational Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tranon.2024.101979","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"101979"}}