{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:02:50Z","timestamp":1790740970104,"version":"4.1.0"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Translational Oncology"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.tranon.2026.102992","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T05:07:15Z","timestamp":1787375235000},"page":"102992","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Integrative single-cell sequencing and machine learning analyses identify chronic inflammation and cancer-associated fibroblast subsets as drivers of adverse outcomes in ovarian cancer"],"prefix":"10.1016","volume":"72","author":[{"given":"Mingqin","family":"Kuang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changmei","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunping","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuchun","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiheng","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baozhen","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0001","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/s41419-022-04510-8","article-title":"Extracellular vesicles in ovarian cancer chemoresistance, metastasis, and immune evasion","volume":"13","author":"Tian","year":"2022","journal-title":"Cell Death. Dis."},{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0002","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s12943-025-02295-w","article-title":"Lactate accumulation induces H4K12la to activate super-enhancer-driven RAD23A expression and promote niraparib resistance in ovarian cancer","volume":"24","author":"Lu","year":"2025","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.tranon.2026.102992_bib0003","doi-asserted-by":"crossref","DOI":"10.1016\/j.neo.2026.101315","article-title":"Molecular landscape and clinical translation of DNA damage response alterations in solid tumors: a pan-cancer perspective on precision oncology","volume":"77","author":"Zhu","year":"2026","journal-title":"Neoplasia"},{"issue":"2","key":"10.1016\/j.tranon.2026.102992_bib0004","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.it.2024.12.006","article-title":"Immune evasion in ovarian cancer: implications for immunotherapy and emerging treatments","volume":"46","author":"Gupta","year":"2025","journal-title":"Trends. Immunol."},{"issue":"5","key":"10.1016\/j.tranon.2026.102992_bib0005","first-page":"436","article-title":"Transforming treatment paradigms: focus on personalized medicine for high-grade serous ovarian cancer","volume":"75","author":"Kordowitzki","year":"2025","journal-title":"CA Cancer J. Clin."},{"issue":"10","key":"10.1016\/j.tranon.2026.102992_bib0006","doi-asserted-by":"crossref","first-page":"4611","DOI":"10.3390\/ijms26104611","article-title":"Ovarian cancer-epidemiology, classification, pathogenesis, treatment, and estrogen receptors' Molecular backgrounds","volume":"26","author":"Smolarz","year":"2025","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.tranon.2026.102992_bib0007","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S1470-2045(24)00674-0","article-title":"Rucaparib versus chemotherapy for treatment of relapsed ovarian cancer with deleterious BRCA1 or BRCA2 mutation (ARIEL4): final results of an international, open-label, randomised, phase 3 trial","volume":"26","author":"Oza","year":"2025","journal-title":"Lancet Oncol."},{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0008","doi-asserted-by":"crossref","DOI":"10.1093\/bjsopen\/zrae161","article-title":"Ovarian cancer risk reduction by salpingectomy during non-gynaecological surgery: scoping review","volume":"9","author":"Fisch","year":"2024","journal-title":"BJS. Open."},{"issue":"12","key":"10.1016\/j.tranon.2026.102992_bib0009","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1007\/s11912-022-01318-9","article-title":"Primary or interval debulking surgery in advanced ovarian cancer: a personalized decision-a literature review","volume":"24","author":"Hudry","year":"2022","journal-title":"Curr. Oncol. Rep."},{"issue":"7","key":"10.1016\/j.tranon.2026.102992_bib0010","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1200\/JCO-24-02589","article-title":"Neoadjuvant chemotherapy for newly diagnosed, advanced ovarian cancer: ASCO guideline update","volume":"43","author":"Gaillard","year":"2025","journal-title":"J. Clin. Oncol."},{"issue":"18","key":"10.1016\/j.tranon.2026.102992_bib0011","doi-asserted-by":"crossref","first-page":"4905","DOI":"10.1016\/j.cell.2024.06.013","article-title":"Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector treg cells for homologous-recombination-deficient tumors","volume":"187","author":"Luo","year":"2024","journal-title":"Cell"},{"issue":"7","key":"10.1016\/j.tranon.2026.102992_bib0012","article-title":"Neoadjuvant chemotherapy before surgery versus surgery followed by chemotherapy for initial treatment in advanced ovarian epithelial cancer","volume":"7","author":"Coleridge","year":"2021","journal-title":"Cochrane Database Syst. Rev."},{"issue":"11","key":"10.1016\/j.tranon.2026.102992_bib0013","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.46325","article-title":"Laparoscopic cytoreduction after neoadjuvant chemotherapy in high-grade epithelial ovarian cancer: a LANCE randomized clinical trial","volume":"7","author":"Rauh-Hain","year":"2024","journal-title":"JAMa Netw. Open."},{"issue":"3","key":"10.1016\/j.tranon.2026.102992_bib0014","doi-asserted-by":"crossref","first-page":"306","DOI":"10.5217\/ir.2022.00118","article-title":"Does caffeine have a double-edged sword role in inflammation and carcinogenesis in the colon?","volume":"21","author":"Mizoguchi","year":"2023","journal-title":"Intest. Res."},{"issue":"4","key":"10.1016\/j.tranon.2026.102992_bib0015","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24043941","article-title":"Emerging role of cancer-associated fibroblasts in progression and treatment of hepatocellular carcinoma","volume":"24","author":"Akk\u0131z","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.tranon.2026.102992_bib0016","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2021\/8840066","article-title":"Crosstalk between tumor-infiltrating immune cells and cancer-associated fibroblasts in tumor growth and immunosuppression of breast cancer","volume":"2021","author":"Soongsathitanon","year":"2021","journal-title":"J. Immunol. Res."},{"issue":"6","key":"10.1016\/j.tranon.2026.102992_bib0017","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1158\/2326-6066.CIR-22-0290","article-title":"Targeting the IL1\u03b2 pathway for cancer immunotherapy remodels the tumor microenvironment and enhances antitumor immune responses","volume":"11","author":"Diwanji","year":"2023","journal-title":"Cancer Immunol. Res."},{"issue":"12","key":"10.1016\/j.tranon.2026.102992_bib0018","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.157215","article-title":"CXCL13-producing CD4+ T cells accumulate in the early phase of tertiary lymphoid structures in ovarian cancer","volume":"7","author":"Ukita","year":"2022","journal-title":"JCI. Insight."},{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0019","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s13048-021-00787-z","article-title":"Comorbidities and inflammation associated with ovarian cancer and its influence on SARS-CoV-2 infection","volume":"14","author":"Chaudhari","year":"2021","journal-title":"J. Ovarian. Res."},{"issue":"2","key":"10.1016\/j.tranon.2026.102992_bib0020","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1158\/1055-9965.EPI-21-0977","article-title":"High prediagnosis inflammation-related risk score associated with decreased ovarian cancer survival","volume":"31","author":"Brieger","year":"2022","journal-title":"Cancer Epidemiol Biomark. Prev"},{"issue":"5","key":"10.1016\/j.tranon.2026.102992_bib0021","article-title":"Targeting PDGF signaling of cancer-associated fibroblasts blocks feedback activation of HIF-1\u03b1 and tumor progression of clear cell ovarian cancer","volume":"5","author":"Mori","year":"2024","journal-title":"Cell Rep. Med."},{"key":"10.1016\/j.tranon.2026.102992_bib0022","article-title":"Immunotherapy: reshape the tumor immune microenvironment","volume":"13","author":"Lv","year":"2022","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.tranon.2026.102992_bib0023","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1038\/s43018-025-00986-3","article-title":"The tumor microenvironment's role in the response to immune checkpoint blockade","volume":"6","author":"Aliazis","year":"2025","journal-title":"Nat. Cancer"},{"issue":"12","key":"10.1016\/j.tranon.2026.102992_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2025.114127","article-title":"CCL19-armed recombinant influenza virus inhibited colorectal cancer growth by remodeling tumor microenvironment","volume":"28","author":"Ou","year":"2025","journal-title":"iScience"},{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0025","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.immuni.2022.12.008","article-title":"Microenvironment-driven metabolic adaptations guiding CD8(+) T cell anti-tumor immunity","volume":"56","author":"Park","year":"2023","journal-title":"Immunity"},{"issue":"3","key":"10.1016\/j.tranon.2026.102992_bib0026","first-page":"540","article-title":"Multi-axis transformer based U-net with class balanced ensemble model for lung disease classification using X-ray images","volume":"33","author":"Maruthai","year":"2025","journal-title":"J. Xray. Sci. Technol."},{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0027","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1186\/s12943-021-01428-1","article-title":"Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives","volume":"20","author":"Mao","year":"2021","journal-title":"Mol. Cancer"},{"issue":"8","key":"10.1016\/j.tranon.2026.102992_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109165","article-title":"Characterizing the tumor microenvironment of metastatic ovarian cancer by single-cell transcriptomics","volume":"35","author":"Olalekan","year":"2021","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0029","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/s41392-024-01885-2","article-title":"Mechanism insights and therapeutic intervention of tumor metastasis: latest developments and perspectives","volume":"9","author":"Shi","year":"2024","journal-title":"Signal. Transduct. Target. Ther."},{"key":"10.1016\/j.tranon.2026.102992_bib0030","article-title":"Editorial: studying the immune microenvironment of liver cancer using artificial intelligence","volume":"16","author":"Zhang","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.tranon.2026.102992_bib0031","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.117714","article-title":"Decoding tumor microenvironment: EMT modulation in breast cancer metastasis and therapeutic resistance, and implications of novel immune checkpoint blockers","volume":"181","author":"Yuan","year":"2024","journal-title":"Biomed. PharmacOther"},{"key":"10.1016\/j.tranon.2026.102992_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.neo.2026.101288","article-title":"SMARCA4 deficiency in glioblastoma: mitochondrial transfer from MSCs and the clinical dilemma in targeting the tumor microenvironment","volume":"73","author":"Yang","year":"2026","journal-title":"Neoplasia"},{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0033","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/cac2.12392","article-title":"Signaling pathways in cancer-associated fibroblasts: recent advances and future perspectives","volume":"43","author":"Fang","year":"2023","journal-title":"Cancer Commun (L.)"},{"issue":"17","key":"10.1016\/j.tranon.2026.102992_bib0034","doi-asserted-by":"crossref","first-page":"8322","DOI":"10.7150\/thno.62378","article-title":"Metabolic reprogramming of cancer-associated fibroblasts and its effect on cancer cell reprogramming","volume":"11","author":"Li","year":"2021","journal-title":"Theranostics"},{"key":"10.1016\/j.tranon.2026.102992_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2024.216859","article-title":"Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma therapy: challenges and opportunities","volume":"591","author":"Qin","year":"2024","journal-title":"Cancer Lett."},{"issue":"5","key":"10.1016\/j.tranon.2026.102992_bib0036","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.ccell.2025.02.024","article-title":"PAI-1-driven SFRP2(high) cancer-associated fibroblasts hijack the abscopal effect of radioimmunotherapy","volume":"43","author":"Zhang","year":"2025","journal-title":"Cancer Cell."},{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0037","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1186\/s13046-024-03077-w","article-title":"Extracellular vesicles activated cancer-associated fibroblasts promote lung cancer metastasis through mitophagy and mtDNA transfer","volume":"43","author":"Zhou","year":"2024","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"3","key":"10.1016\/j.tranon.2026.102992_bib0038","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.ccell.2023.12.021","article-title":"Cancer-associated fibroblast phenotypes are associated with patient outcome in non-small cell lung cancer","volume":"42","author":"Cords","year":"2024","journal-title":"Cancer Cell."},{"issue":"4","key":"10.1016\/j.tranon.2026.102992_bib0039","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.3390\/ijms23042218","article-title":"GLIS1 in cancer-associated fibroblasts regulates the migration and invasion of ovarian cancer cells","volume":"23","author":"Kim","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0040","doi-asserted-by":"crossref","first-page":"112","DOI":"10.3390\/biomedicines11010112","article-title":"Patient-derived primary cancer-associated fibroblasts mediate resistance to anti-angiogenic drug in ovarian cancers","volume":"11","author":"Sulaiman","year":"2023","journal-title":"Biomedicines"},{"issue":"8","key":"10.1016\/j.tranon.2026.102992_bib0041","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1038\/s41419-022-05129-5","article-title":"CRMP2 derived from cancer associated fibroblasts facilitates progression of ovarian cancer via HIF-1\u03b1-glycolysis signaling pathway","volume":"13","author":"Jin","year":"2022","journal-title":"Cell Death. Dis."},{"issue":"7","key":"10.1016\/j.tranon.2026.102992_bib0042","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2024.119801","article-title":"Reprogramming of normal fibroblasts into ovarian cancer-associated fibroblasts via non-vesicular paracrine signaling induces an activated fibroblast phenotype","volume":"1871","author":"Axemaker","year":"2024","journal-title":"Biochim. Biophys. Acta Mol. Cell Res."},{"issue":"6","key":"10.1016\/j.tranon.2026.102992_bib0043","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1007\/s12094-022-03054-9","article-title":"Cancer-associated fibroblasts contribute to cancer metastasis and apoptosis resistance in human ovarian cancer via paracrine SDF-1\u03b1","volume":"25","author":"Dai","year":"2023","journal-title":"Clin. Transl. Oncol."},{"issue":"5","key":"10.1016\/j.tranon.2026.102992_bib0044","doi-asserted-by":"crossref","DOI":"10.1016\/j.ygeno.2023.110703","article-title":"Exosomes derived from ovarian cancer cells regulate proliferation and migration of cancer-associated fibroblasts","volume":"115","author":"Ding","year":"2023","journal-title":"Genomics"},{"issue":"2","key":"10.1016\/j.tranon.2026.102992_bib0045","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.ygyno.2022.09.003","article-title":"Cancer-associated fibroblasts-derived FMO2 as a biomarker of macrophage infiltration and prognosis in epithelial ovarian cancer","volume":"167","author":"Yu","year":"2022","journal-title":"Gynecol. Oncol."},{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0046","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-024-54295-x","article-title":"Immunotherapy that improves response to chemotherapy in high-grade serous ovarian cancer","volume":"15","author":"Elorbany","year":"2024","journal-title":"Nat. Commun."},{"issue":"10","key":"10.1016\/j.tranon.2026.102992_bib0047","doi-asserted-by":"crossref","first-page":"16951","DOI":"10.18632\/oncotarget.15208","article-title":"ELF3 is a negative regulator of epithelial-mesenchymal transition in ovarian cancer cells","volume":"8","author":"Yeung","year":"2017","journal-title":"Oncotarget"},{"issue":"4","key":"10.1016\/j.tranon.2026.102992_bib0048","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1002\/path.4649","article-title":"In vitro and in vivo correlates of physiological and neoplastic human Fallopian tube stem cells","volume":"238","author":"Yamamoto","year":"2016","journal-title":"J. Pathol."},{"key":"10.1016\/j.tranon.2026.102992_bib0049","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1186\/1471-2407-13-549","article-title":"Identification of the IGF1\/PI3K\/NF \u03bab\/ERK gene signalling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancer","volume":"13","author":"Koti","year":"2013","journal-title":"BMC. Cancer"},{"issue":"13","key":"10.1016\/j.tranon.2026.102992_bib0050","first-page":"26","article-title":"Mitochondrial fragmentation and long noncoding RNA MALAT1 in diabetic retinopathy","author":"Kowluru","year":"2025","journal-title":"Int. J. Mol. Sci."},{"issue":"Pt 6","key":"10.1016\/j.tranon.2026.102992_bib0051","article-title":"Identification of a lactylation-related gene signature as the novel biomarkers for early diagnosis of acute myocardial infarction","volume":"282","author":"Zhu","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0052","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/ijc.33408","article-title":"Tumor-associated macrophage-targeted therapeutics in ovarian cancer","volume":"149","author":"An","year":"2021","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.tranon.2026.102992_bib0053","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2022.174752","article-title":"Ovarian cancer and KiSS-1 gene expression: a consideration of the use of Kisspeptin plus Kisspeptin aptamers in diagnostics and therapy","volume":"917","author":"Singh","year":"2022","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.tranon.2026.102992_bib0054","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.ygyno.2021.07.030","article-title":"Risk of venous thromboembolism in ovarian cancer patients receiving neoadjuvant chemotherapy","volume":"163","author":"Basaran","year":"2021","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.tranon.2026.102992_bib0055","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ygyno.2023.06.001","article-title":"Trends in the use of neoadjuvant chemotherapy for low-grade serous ovarian cancer in the United States","volume":"175","author":"Silberman","year":"2023","journal-title":"Gynecol. Oncol."},{"issue":"4","key":"10.1016\/j.tranon.2026.102992_bib0056","doi-asserted-by":"crossref","first-page":"2617","DOI":"10.1245\/s10434-021-11087-7","article-title":"Cytoreductive surgery with or without HIPEC after neoadjuvant chemotherapy in ovarian cancer: a phase 3 clinical trial","volume":"29","author":"Antonio","year":"2022","journal-title":"Ann. Surg. Oncol."},{"issue":"23","key":"10.1016\/j.tranon.2026.102992_bib0057","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202502370RR","article-title":"The role of STING-mediated activation of the integrated stress response in inflammation-induced depletion of ovarian reserve","volume":"39","author":"Wang","year":"2025","journal-title":"FASEB J."}],"container-title":["Translational Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936523326003281?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936523326003281?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:42:22Z","timestamp":1790739742000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936523326003281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":57,"alternative-id":["S1936523326003281"],"URL":"https:\/\/doi.org\/10.1016\/j.tranon.2026.102992","relation":{},"ISSN":["1936-5233"],"issn-type":[{"value":"1936-5233","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Integrative single-cell sequencing and machine learning analyses identify chronic inflammation and cancer-associated fibroblast subsets as drivers of adverse outcomes in ovarian cancer","name":"articletitle","label":"Article Title"},{"value":"Translational Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tranon.2026.102992","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"102992"}}