{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T07:46:53Z","timestamp":1791704813808,"version":"4.3.4"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T00:00:00Z","timestamp":1789862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Translational Oncology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.tranon.2026.103051","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:31:54Z","timestamp":1790710314000},"page":"103051","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Distinct genomic landscape of non-small cell lung cancer in Bangladeshi patients: Implications for precision oncology in a resource-limited setting"],"prefix":"10.1016","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-8067-9883","authenticated-orcid":false,"given":"Md.","family":"Al Amin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manisha","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradip Kumar","family":"Nath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu Shadat Mohammod","family":"Noman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramendu","family":"Parial","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tranon.2026.103051_bib0001","article-title":"Global cancer statistics 2024: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","author":"Bray","year":"2025","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.tranon.2026.103051_bib0002","series-title":"GLOBOCAN 2022: Bangladesh Fact Sheet","year":"2024"},{"issue":"4","key":"10.1016\/j.tranon.2026.103051_bib0003","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.annonc.2022.12.009","article-title":"Oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up","volume":"34","author":"Hendriks","year":"2023","journal-title":"Ann. Oncol."},{"issue":"4","key":"10.1016\/j.tranon.2026.103051_bib0004","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.annonc.2022.12.013","article-title":"Non-oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up","volume":"34","author":"Hendriks","year":"2023","journal-title":"Ann. Oncol."},{"issue":"5","key":"10.1016\/j.tranon.2026.103051_bib0005","doi-asserted-by":"crossref","first-page":"497","DOI":"10.6004\/jnccn.2022.0025","article-title":"Non-small cell Lung Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology","volume":"20","author":"Ettinger","year":"2022","journal-title":"J. Natl. Compr. Canc. Netw."},{"issue":"2","key":"10.1016\/j.tranon.2026.103051_bib0006","first-page":"99","article-title":"EGFR mutation incidence in non-small-cell lung cancer of Asian and Western populations: a meta-analysis","volume":"20","author":"Midha","year":"2015","journal-title":"Biomarkers"},{"issue":"9","key":"10.1016\/j.tranon.2026.103051_bib0007","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/s41568-019-0179-8","article-title":"Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy","volume":"19","author":"Skoulidis","year":"2019","journal-title":"Nat. Rev. Cancer"},{"issue":"3","key":"10.1016\/j.tranon.2026.103051_bib0008","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.jtho.2017.12.001","volume":"13","author":"Lindeman","year":"2018","journal-title":"J. Thorac. Oncol."},{"issue":"10","key":"10.1016\/j.tranon.2026.103051_bib0009","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1016\/j.jtho.2021.06.017","article-title":"Liquid biopsy for advanced non-small cell lung cancer: a consensus statement from the International Association for the Study of Lung Cancer","volume":"16","author":"Rolfo","year":"2021","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.tranon.2026.103051_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.jlb.2023.100131","article-title":"Clinical application of liquid biopsy genomic profiling in NSCLC: Asian perspectives","volume":"3","author":"Li","year":"2024","journal-title":"J Liquid Biopsy"},{"issue":"13","key":"10.1016\/j.tranon.2026.103051_bib0011","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241310803","article-title":"Liquid biopsy in NSCLC: an investigation with multiple clinical implications","volume":"24","author":"Bertoli","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"7689","key":"10.1016\/j.tranon.2026.103051_bib0012","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/nature25183","article-title":"The biology and management of non-small cell lung cancer","volume":"553","author":"Herbst","year":"2018","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.tranon.2026.103051_bib0013","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.3390\/curroncol29030174","article-title":"Genomic landscape of non-small cell lung cancer (NSCLC) in East Asia using circulating tumor DNA (ctDNA) in clinical practice","volume":"29","author":"Cho","year":"2022","journal-title":"Curr. Oncol."},{"key":"10.1016\/j.tranon.2026.103051_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.tranon.2023.101869","article-title":"Clinical utility of next-generation sequencing of plasma cell-free DNA for the molecular profiling of patients with NSCLC at diagnosis and disease progression","volume":"41","author":"Del Re","year":"2024","journal-title":"Transl. Oncol."},{"issue":"1","key":"10.1016\/j.tranon.2026.103051_bib0015","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1186\/s13045-017-0536-6","article-title":"The emerging roles of NGS-based liquid biopsy in non-small cell lung cancer","volume":"10","author":"Zhang","year":"2017","journal-title":"J. Hematol. Oncol."},{"issue":"9","key":"10.1016\/j.tranon.2026.103051_bib0016","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1016\/j.jtho.2018.05.030","article-title":"Liquid biopsy for advanced non-small cell lung cancer (NSCLC): a statement paper from the IASLC","volume":"13","author":"Rolfo","year":"2018","journal-title":"J. Thorac. Oncol."},{"issue":"1","key":"10.1016\/j.tranon.2026.103051_bib0020","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.1038\/s41467-019-10879-6","article-title":"Untangling the evolutionary roots of lung cancer","volume":"10","author":"Devarakonda","year":"2019","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.tranon.2026.103051_bib0021","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1097\/JTO.0b013e3181d57f6e","article-title":"Pathologic diagnosis of advanced lung cancer based on small biopsies and cytology: a paradigm shift","volume":"5","author":"Travis","year":"2010","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.tranon.2026.103051_bib0022","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1200\/EDBK_237863","article-title":"Biomarker testing for patients with advanced non-small cell lung cancer: real-world issues and tough choices","volume":"39","author":"Pennell","year":"2019","journal-title":"Am. Soc. Clin. Oncol. Educ. Book."},{"issue":"7","key":"10.1016\/j.tranon.2026.103051_bib0023","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1093\/annonc\/mdv208","article-title":"Biomarker testing and time to treatment decision in patients with advanced nonsmall-cell lung cancer","volume":"26","author":"Lim","year":"2015","journal-title":"Ann. Oncol."},{"issue":"15","key":"10.1016\/j.tranon.2026.103051_bib0024","doi-asserted-by":"crossref","first-page":"4691","DOI":"10.1158\/1078-0432.CCR-19-0624","article-title":"Clinical utility of comprehensive cell-free DNA analysis to identify genomic biomarkers in patients with newly diagnosed metastatic non-small cell lung cancer","volume":"25","author":"Leighl","year":"2019","journal-title":"Clin. Cancer Res."},{"issue":"9","key":"10.1016\/j.tranon.2026.103051_bib0025","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1038\/d41587-019-00022-7","article-title":"Investors keep the faith in cancer liquid biopsies","volume":"37","author":"Sheridan","year":"2019","journal-title":"Nat. Biotechnol."},{"issue":"Suppl 1","key":"10.1016\/j.tranon.2026.103051_bib0026","doi-asserted-by":"crossref","first-page":"S113","DOI":"10.21037\/jtd.2018.12.18","article-title":"Circulating free tumor DNA in non-small cell lung cancer (NSCLC): clinical application and future perspectives","volume":"11","author":"Herbreteau","year":"2019","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.tranon.2026.103051_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.critrevonc.2021.103394","article-title":"Circulating tumor DNA in cancer: predictive molecular pathology meets mathematics","volume":"163","author":"Malapelle","year":"2021","journal-title":"Crit. Rev. Oncol. Hematol."},{"issue":"(3\u20134","key":"10.1016\/j.tranon.2026.103051_bib0028","first-page":"241","article-title":"[Nuclear Acids In Human Blood Plasma]","volume":"142","author":"Mandel","year":"1948","journal-title":"C. R. Seances Soc. Biol. Fil."},{"issue":"4","key":"10.1016\/j.tranon.2026.103051_bib0029","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/nrc.2017.7","article-title":"Liquid biopsies come of age: towards implementation of circulating tumour DNA","volume":"17","author":"Wan","year":"2017","journal-title":"Nat. Rev. Cancer"},{"issue":"2","key":"10.1016\/j.tranon.2026.103051_bib0030","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S1470-2045(10)70087-5","article-title":"New driver mutations in non-small-cell lung cancer","volume":"12","author":"Pao","year":"2011","journal-title":"Lancet Oncol."},{"issue":"3668","key":"10.1016\/j.tranon.2026.103051_bib0031","first-page":"374","article-title":"Circulating dna AS a possible factor in oncogenesis","volume":"148","author":"Bendich","year":"1965","journal-title":"Science (1979)"},{"issue":"11","key":"10.1016\/j.tranon.2026.103051_bib0032","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/j.annonc.2020.07.014","article-title":"Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group","volume":"31","author":"Mosele","year":"2020","journal-title":"Ann. Oncol."},{"issue":"7","key":"10.1016\/j.tranon.2026.103051_bib0033","doi-asserted-by":"crossref","first-page":"740","DOI":"10.6004\/jnccn.2010.0056","article-title":"Non\u2013Small cell lung cancer","volume":"8","author":"Ettinger","year":"2010","journal-title":"J. Natl. Compr. Canc. Netw."},{"issue":"1","key":"10.1016\/j.tranon.2026.103051_bib0034","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/s43018-019-0008-8","article-title":"Multimodal genomic features predict outcome of immune checkpoint blockade in non-small-cell lung cancer","volume":"1","author":"Anagnostou","year":"2020","journal-title":"Nat. Cancer"},{"issue":"6","key":"10.1016\/j.tranon.2026.103051_bib0017","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1038\/ng.3564","article-title":"Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas","volume":"48","author":"Campbell","year":"2016","journal-title":"Nat. Genet."},{"issue":"7511","key":"10.1016\/j.tranon.2026.103051_bib0018","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/nature13385","article-title":"Comprehensive molecular profiling of lung adenocarcinoma","volume":"511","year":"2014","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.tranon.2026.103051_bib0019","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/s41588-019-0569-6","article-title":"Genomic landscape of lung adenocarcinoma in East Asians","volume":"52","author":"Chen","year":"2020","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/j.tranon.2026.103051_bib0035","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1093\/jnci\/djy156","article-title":"A prospective study of circulating tumor DNA to guide matched targeted therapy in lung cancers","volume":"111","author":"Sabari","year":"2019","journal-title":"J. Natl. Cancer Inst."}],"container-title":["Translational Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936523326003876?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936523326003876?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T07:32:17Z","timestamp":1791703937000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936523326003876"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":35,"alternative-id":["S1936523326003876"],"URL":"https:\/\/doi.org\/10.1016\/j.tranon.2026.103051","relation":{},"ISSN":["1936-5233"],"issn-type":[{"value":"1936-5233","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Distinct genomic landscape of non-small cell lung cancer in Bangladeshi patients: Implications for precision oncology in a resource-limited setting","name":"articletitle","label":"Article Title"},{"value":"Translational Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tranon.2026.103051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"103051"}}